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Dietary supplement

Citrus Bergamot 500 mg Ingredients & Drug Interactions

by longlifenutri

Capsule Category: Botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Citrus Bergamot 500 mg is a dietary supplement by longlifenutri with 1 active ingredient. Its ingredients are commonly taken for high cholesterol, heart and metabolic health, anxiety and stress (aromatherapy).Based on those ingredients, 410 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Citrus Bergamont Fruit Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Citrus Bergamot 500 mg by longlifenutri

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: citrus bergamot fruit extract at 500 mg per capsule. Bergamot is a citrus fruit sometimes used for cholesterol and liver health.

The capsule also contains two inactive ingredients—cellulose and magnesium stearate—which are common binders and fillers.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: Supports blood glucose metabolism and healthy cholesterol levels.
  • We looked for evidence on: Hyperlipidemia, Impaired glucose tolerance (prediabetes), Metabolic syndrome, Nonalcoholic fatty liver disease (NAFLD), Obesity, Dyslipidemia — and 1 related terms.
  • The strongest evidence on file: Bergamot is rated "Possibly Effective" for Hyperlipidemia (Natural Medicines).
  • Also on file: Bergamot is rated "Insufficient Reliable Evidence To Rate" for Nonalcoholic fatty liver disease (NAFLD), Obesity, Impaired glucose tolerance (prediabetes), Metabolic syndrome.

The data shows bergamot is possibly effective for high cholesterol (hyperlipidemia). For mental alertness, the evidence suggests it's possibly ineffective.

For nonalcoholic fatty liver disease and autism spectrum disorder, there isn't enough reliable evidence in our data to say whether it works or doesn't.

The evidence, ingredient by ingredient Bergamot

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

The oral extract appears generally well tolerated in short-term use, though one person in clinical research reported heartburn. The essential oil, however, can be toxic if swallowed and causes sun-related skin reactions—so this product is the extract form, not the oil.

The safety data advises against bergamot during pregnancy and breastfeeding because there isn't enough information to know it's safe. Topically, bergamot can cause blisters, redness, skin lesions, and increased sensitivity to sunlight, especially in fair-skinned people.

Side effects, ingredient by ingredient Bergamot

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Bergamot.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 410 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your pharmacist if you take photosensitizing drugs (medications that increase sun sensitivity) or antidiabetes drugs (blood-sugar medications). Both have moderate interactions with bergamot, and both can cause real problems when combined.

No interactions are documented for any other drug types in our data, but the total medication count is large, so your pharmacist can search your full list here.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

If you're interested in bergamot for cholesterol support and have no photosensitizing medications or blood-sugar medications, this may be worth considering. But check your exact medications first—408 drugs interact with bergamot in some way, and pregnancy or breastfeeding are reasons to avoid it.

Talk to your pharmacist about whether it fits your situation.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jul 25, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Citrus Bergamot 500 mg, straight from the product label.

Brand longlifenutri
Barcode (UPC) X002RFCH4T
Net contents 120 Vegetarian Capsule(s)
Market status On market
Date entered into DSLD Jul 25, 2024
DSLD ID 316468
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Citrus Bergamot 500 mg by longlifenutri, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Vegetarian Capsule(s)
Maximum serving Sizes:
2 Vegetarian Capsule(s)
Servings per container
120
UPC/BARCODE
X002RFCH4T
IngredientAmount% DV
Citrus Bergamont Fruit Extract500 mg--

Other ingredients: Cellulose, Magnesium Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Supports blood glucose metabolism Supports healthy cholesterol levels Powerful antioxidant

Gluten free GMO free

No wheat, Gluten, Egg, Dairy, Soy, Shellfish, Tree nuts

Seals/Symbols

Made in USA

Suggested/Recommended/Usage/Directions

Suggested use: As a dietary supplement for adults, take one (1) or two (2) vegetarian capsules daily, preferably with a glass of water or as directed by your healthcare professional.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

FDA Statement of Identity

Premium Quality Dietary Supplement

Precautions

Keep out of reach of children.

Caution: Pregnant or nursing women, under the age of 18 or individuals with a known medical condition should consult a physician before using this or any dietary supplement.

Caution: Pregnant or nursing women, under the age of 18 or individuals with a known medical condition should consult a physician before using this or any dietary supplement.

Discontinue use if you experience any adverse reaction to this product.

Storage

Store in a cool, dry place.

See for yourself

Citrus Bergamot 500 mg by longlifenutri label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Citrus Bergamot 500 mg by longlifenutri

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Vegetarian Capsule(s) Dosage formCapsule Servings per container120 Amounts shown are per serving.

Citrus Bergamont Fruit Extract

Interacts with
410 drugs
500 mg per serving Form: Polyphenolic flavanones

Bergamot is a Mediterranean citrus fruit, and its standardized extract is most often used to support cholesterol and heart health, with some early but...

Citrus Bergamont Fruit Extract monograph & interactions

Other (inactive) ingredients: Cellulose, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Citrus Bergamot 500 mg by longlifenutri Drug Interactions

Want to check YOUR meds against Citrus Bergamot 500 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
410Drugs
410 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Citrus Bergamot 500 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Citrus Bergamont Fruit Extract2 drug types · 410 drugs

Antidiabetes Drugs

Theoretically, taking bergamot with antidiabetes drugs might increase the risk of hypoglycemia.
Animal research suggests that bergamot juice has hypoglycemic effects.

Likelihood Possible Evidence D
Photosensitizing Drugs

Theoretically, topical bergamot essential oil might increase the risk of side effects when used along with photosensitizing drugs.
Bergamot contains bergapten, which has photosensitizing effects.

Likelihood Probable Evidence D
The maker

Brand information

Manufacturer and brand details for Citrus Bergamot 500 mg, from the product label.

longlifenutri

See all longlifenutri products
Name
LongLifeNutri
City
Wilmington
State
DE
ZipCode
19801
Web Address
www.longlifenutri.com
Pharmacist Counseling Corner

Citrus Bergamot 500 mg by longlifenutri: Common Questions

Does Citrus Bergamot 500 mg by longlifenutri interact with any medications?
Yes. Based on its ingredients, Citrus Bergamot 500 mg has a known interaction with 410 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Citrus Bergamot 500 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant or breastfeeding?
The safety data advises against bergamot during pregnancy and breastfeeding. There isn't enough information to know it's safe in either situation. Talk with your doctor or pharmacist about your options.
Will this lower my blood sugar?
Animal research suggests bergamot juice can lower blood sugar. If you take antidiabetes medications, combining them with this supplement theoretically increases the risk of low blood sugar (hypoglycemia). Check with your pharmacist before starting.
Can I use this if I'm taking a medication that makes my skin sun-sensitive?
No. Bergamot contains a photosensitizing compound, and using it with drugs that also increase sun sensitivity theoretically raises your risk of sun-related skin side effects. Ask your pharmacist which of your medications fall into this category.
What are the side effects of taking bergamot orally?
The oral extract is generally well tolerated short-term. One person in clinical research reported heartburn. Topical bergamot is riskier and can cause blisters, redness, skin lesions, and photosensitivity—but this product is taken by mouth, not applied to skin.
Does bergamot work for high cholesterol?
Yes—the evidence shows it's possibly effective for lowering cholesterol (hyperlipidemia). For mental alertness, it appears ineffective. For liver health and autism, there isn't enough reliable evidence yet.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Citrus Bergamot 500 mg is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Citrus Bergamot 500 mg label
Go deeper

The Full Monographs Behind Citrus Bergamot 500 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Citrus Bergamot 500 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 17 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Bergamot 17 references
  1. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
  2. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  3. Naganuma M, Hirose S, Nakayama Y, et al. A study of the phototoxicity of lemon oil. Arch Dermatol Res 1985;278:31-6. . PubMed
  4. Kaddu, S., Kerl, H., and Wolf, P. Accidental bullous phototoxic reactions to bergamot aromatherapy oil. J.Am.Acad.Dermatol. 2001;45(3):458-461. PubMed
  5. Finsterer, J. Earl Grey tea intoxication. Lancet 4-27-2002;359(9316):1484. PubMed
  6. Gruson, L. M. and Chang, M. W. Berloque dermatitis mimicking child abuse. Arch.Pediatr.Adolesc.Med. 2002;156(11):1091-1093. PubMed
  7. Weisenseel, P. and Woitalla, S. [Toxic mustard plaster dematitis and phototoxic dematitis after application of bergamot oil]. MMW.Fortschr.Med. 12-15-2005;147(51-52):53, 55.
  8. Placzek, M., Fromel, W., Eberlein, B., Gilbertz, K. P., and Przybilla, B. Evaluation of phototoxic properties of fragrances. Acta Derm.Venereol. 2007;87(4):312-316. PubMed
  9. Mollace, V., Sacco, I., Janda, E., Malara, C., Ventrice, D., Colica, C., Visalli, V., Muscoli, S., Ragusa, S., Muscoli, C., Rotiroti, D., and Romeo, F. Hypolipemic and hypoglycaemic activity of bergamot polyphenols: from animal models to human studies. F PubMed
  10. Morliere, P., Huppe, G., Averbeck, D., Young, A. R., Santus, R., and Dubertret, L. In vitro photostability and photosensitizing properties of bergamot oil. Effects of a cinnamate sunscreen. J.Photochem.Photobiol.B 1990;7(2-4):199-208. PubMed
  11. Young, A. R., Walker, S. L., Kinley, J. S., Plastow, S. R., Averbeck, D., Morliere, P., and Dubertret, L. Phototumorigenesis studies of 5-methoxypsoralen in bergamot oil: evaluation and modification of risk of human use in an albino mouse skin model. J.P PubMed
  12. Girard, J., Unkovic, J., Delahayes, J., and Lafille, C. [Phototoxicity of Bergamot oil. Comparison between humans and guinea pigs]. Dermatologica 1979;158(4):229-243.
  13. Zaynoun, S. T., Johnson, B. E., and Frain-Bell, W. A study of oil of bergamot and its importance as a phototoxic agent. II. Factors which affect the phototoxic reaction induced by bergamot oil and psoralen derivatives. Contact Dermatitis 1977;3(5):225-23 PubMed
  14. Zacher, K. D. and Ippen, H. [Contact dermatitis caused by bergamot oil]. Derm.Beruf.Umwelt. 1984;32(3):95-97.
  15. Yasui, Y. and Hirone, T. Action spectrum for bergamot-oil phototoxicity measured by sunburn cell counting. J.Dermatol. 1994;21(5):319-322. PubMed
  16. Zaynoun, S. T., Johnson, B. E., and Frain-Bell, W. A study of oil of bergamot and its importance as a phototoxic agent. I. Characterization and quantification of the photoactive component. Br.J.Dermatol. 1977;96(5):475-482. PubMed
  17. Bruno A, Pandolfo G, Crucitti M, Cedro C, Zoccali RA, Muscatello MRA. Bergamot Polyphenolic Fraction Supplementation Improves Cognitive Functioning in Schizophrenia: Data From an 8-Week, Open-Label Pilot Study. J Clin Psychopharmacol 2017;37(4):468-71. PubMed

See these in context on the Bergamot monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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