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Dietary supplement

Coccinia Ingredients & Drug Interactions

by Hawaii Pharm

Coccinia label
See full label image
Liquid Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Coccinia against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Coccinia is a dietary supplement by Hawaii Pharm with 1 active ingredient. Its ingredients are commonly taken for blood sugar support, digestive complaints, skin conditions.Based on those ingredients, 86 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Coccinia Fruit Extract, Dry. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Coccinia by Hawaii Pharm

Ask about any prescription or over-the-counter medication and we check it for interactions with Coccinia by Hawaii Pharm — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Coccinia by Hawaii Pharm

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product has one active ingredient: Coccinia fruit extract, also called ivy gourd. Ivy gourd is a plant traditionally used for blood sugar support.

The liquid form also contains alcohol, water, and glycerin as inactive ingredients.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Ivy Gourd's overall clinical evidence instead.

Moderate

Some clinical evidence supports Ivy Gourd for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Diabetes — rated "Possibly Effective" (Natural Medicines).

Ivy gourd is rated possibly effective for diabetes support based on the evidence we hold. That means there's some promise, but more research is needed to be sure how well it works or who benefits most.

Talk with your doctor about whether it fits into your overall diabetes care plan.

The evidence, ingredient by ingredient Ivy Gourd

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Ivy gourd leaf is generally well tolerated when taken by mouth. A small number of people report mild nausea, headache, or drowsiness.

Because supplement doses haven't been as thoroughly studied as food amounts, caution is warranted—especially if you have blood sugar concerns. The safety data advises against using medicinal amounts during pregnancy, and it is best to avoid medicinal use while breastfeeding.

If you're pregnant or nursing, talk with your doctor or pharmacist before taking this product.

Side effects, ingredient by ingredient Ivy Gourd

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Ivy Gourd.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 86 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check any antidiabetes drugs you take before starting this product—the main concern is a Moderate risk of low blood sugar when combined with these medications.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

Coccinia may be worth considering if you're looking for traditional blood sugar support and have talked with your doctor about it. If you take any diabetes medication, this product needs a pharmacist or doctor check first because of the risk of low blood sugar.

Always monitor your blood glucose if you decide to use it alongside your medications.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 25, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Coccinia, straight from the product label.

Brand Hawaii Pharm
Barcode (UPC) 840253615374
Net contents 4 Fluid Ounce(s); 120 mL
Market status On market
Date entered into DSLD Jun 25, 2025
DSLD ID 331810
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Coccinia by Hawaii Pharm, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
0.7 mL
Maximum serving Sizes:
1 mL
Servings per container
120
UPC/BARCODE
840253615374
IngredientAmount% DV
Coccinia Fruit Extract, Dry983 mg--

Other ingredients: Alcohol, Water, Glycerin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)

Hawaii Pharm Herbal Extract Highest quality since 2008

Suggested/Recommended/Usage/Directions

Suggested use: Shake well before using. For adults add about 20-30 drops (0.7-1 ml, one full squeeze of the dropper bulb) to some juice or water, up to 4 times a day.

Precautions

Warning: We recommend to seek expert medical advice before taking.

Do not use if you are allergic to any ingredients.

Consult your physician before giving to children under 18, during pregnancy, if nursing or taking medications.

Consult your physician before giving to children under 18, during pregnancy, if nursing or taking medications. Keep out of the reach of children!

May affect the ability to drive and operate machinery. May have contraindications, can cause side effects and adverse reactions. Do not use if seal is broken or missing.

Storage

Store in a cool dry place.

Seals/Symbols

cGMP Made in compliance with cGMP 21 CFR 111 in an FDA registered and inspected facility.

USA Made in United States of America

FDA Disclaimer Statement

This product has not been evaluated by the FDA and is not intended to diagnose, treat, cure or prevent any disease.

General Statements

Scan this QR code to get 15% discount on your next purchase Limited time deal

Formula

Coccinia cordifolia

Organic Alcohol Based

Formulation

Only natural ingredients Purity is laboratory tested and verified Not tested on animals

All the raw materials are gluten-free by their nature No artificial colors, flavors, or preservatives

Organic Alcohol Based

Made in USA, Hawaii

FDA Statement of Identity

Herbal Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Coccinia by Hawaii Pharm label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Coccinia label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Coccinia by Hawaii Pharm

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size0.7 mL Dosage formLiquid Servings per container120 Amounts shown are per serving.

Coccinia Fruit Extract, Dry

Interacts with
86 drugs
983 mg per serving Form: Coccinia cordifolia Fruit Extract, Dry

Ivy gourd is a tropical vine widely eaten as a vegetable and used in traditional medicine, most often for blood sugar support. Early human research hi...

Coccinia Fruit Extract, Dry monograph & interactions

Other (inactive) ingredients: Alcohol, Water, Glycerin. These complete the product’s ingredient list but are not active constituents.

Interaction report

Coccinia by Hawaii Pharm Drug Interactions

Want to check YOUR meds against Coccinia?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
86Drugs
86 Moderate

Ingredients driving the most interactions

Coccinia Fruit Extract, Dry 86

Individual Drug Interactions

The ingredients in Coccinia interact with 86 drugs. Click any drug to see the details.

1 of the 1 ingredient in Coccinia interact with drugs. Each result below shows which ingredient is responsible. Coccinia Fruit Extract, Dry

Each ingredient & the kinds of drugs it affects

For each ingredient in Coccinia with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Coccinia Fruit Extract, Dry1 drug type · 86 drugs

Antidiabetes Drugs

Ivy gourd may lower blood glucose levels and might have additive effects when used with antidiabetes drugs. This might increase the risk of hypoglycemia in some patients. Monitor blood glucose levels closely.

Likelihood Probable Evidence A
Coccinia Fruit Extract, Dry full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Coccinia, from the product label.

Hawaii Pharm

See all Hawaii Pharm products
Name
Hawaii Pharm LLC
Street Address
510 Sumner St STE 613
City
Honolulu
State
HI
ZipCode
96817
Phone Number
888-542-9244
Web Address
Hawaiipharm.com
Pharmacist Counseling Corner

Coccinia by Hawaii Pharm: Common Questions

Does Coccinia by Hawaii Pharm interact with any medications?
Yes. Based on its ingredients, Coccinia has a known interaction with 86 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Coccinia contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take Coccinia if I'm pregnant or breastfeeding?
The safety data advises against medicinal amounts of ivy gourd during pregnancy because there isn't enough information. During breastfeeding, it's best to avoid medicinal use. Talk with your doctor or pharmacist for personalized advice if you're thinking about using this product in either situation.
What side effects might I notice from ivy gourd?
Ivy gourd leaf is generally well tolerated. A small number of people report mild nausea, headache, or drowsiness. If any of these bother you, let your pharmacist know.
Does this product actually work for blood sugar?
Ivy gourd is rated possibly effective for diabetes based on the evidence we have, which means there's some promise but more research is needed. It shouldn't replace your prescribed diabetes care—use it as a complement, and always talk with your doctor about how it fits into your plan.
Why is this a liquid rather than a capsule or tablet?
The product facts don't explain the reason for the liquid form, but the liquid contains alcohol, water, and glycerin as inactive ingredients to carry the extract.
What is ivy gourd and why is it in this supplement?
Ivy gourd is a plant traditionally used for blood sugar support. It's the active ingredient in this Coccinia product because of its possibly effective rating for diabetes.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Coccinia is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Coccinia label
Go deeper

The Full Monographs Behind Coccinia’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Ivy Gourd

Interacts with 86 drugs

Ivy gourd is a tropical vine widely eaten as a vegetable and used in traditional medicine, most often for blood sugar support. Early human research hints it may modestly lower blood sugar, b...

Read the full Ivy Gourd monograph →
Sources

Sources & How We Checked

Coccinia's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 5 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Ivy Gourd 5 references
  1. Khan AK, AKhtar S, Mahtab H. Treatment of diabetes mellitus with Coccinia indica. Br Med J 1980;280:1044. PubMed
  2. Munasinghe MAAK, Abeysena C, Yaddehige IS, et al. Blood sugar lowering effect of Coccinia grandis (L.) J. Voight: path for a new drug for diabetes mellitus. Exp Diabetes Res 2011; doi: 10.1155/2011/978762.
  3. Venkateswaran, S. and Pari, L. Effect of Coccinia indica leaf extract on plasma antioxidants in streptozotocin- induced experimental diabetes in rats. Phytother.Res 2003;17(6):605-608.
  4. Kuriyan, R., Rajendran, R., Bantwal, G., and Kurpad, A. V. Effect of supplementation of Coccinia cordifolia extract on newly detected diabetic patients. Diabetes Care 2008;31(2):216-220.
  5. Wasana KGP, Attanayake AP, Weerarathna TP, Jayatilaka KAPW. Efficacy and safety of a herbal drug of Coccinia grandis (Linn.) Voigt in patients with type 2 diabetes mellitus: A double blind randomized placebo controlled clinical trial. Phytomedicine. 2021 PubMed

See these in context on the Ivy Gourd monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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