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Dietary supplement

Coccinia Ingredients & Drug Interactions

by Herbal Terra

Coccinia label
See full label image
Liquid Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Coccinia against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Coccinia is a dietary supplement by Herbal Terra with 1 active ingredient. Its ingredients are commonly taken for blood sugar support, digestive complaints, skin conditions.Based on those ingredients, 86 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are certified organic Coccinia dried fruit liquid extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Coccinia by Herbal Terra

Ask about any prescription or over-the-counter medication and we check it for interactions with Coccinia by Herbal Terra — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Coccinia by Herbal Terra

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 16, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

Coccinia contains one active ingredient: certified organic Ivy Gourd dried fruit liquid extract. Ivy gourd is a plant used traditionally in folk medicine and appears in this product in a concentrated liquid form.

The product also includes Menstruum, an inactive ingredient used to prepare and preserve the extract.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Ivy Gourd's overall clinical evidence instead.

Moderate

Some clinical evidence supports Ivy Gourd for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Diabetes — rated "Possibly Effective" (Natural Medicines).

The evidence suggests Ivy Gourd is possibly effective for diabetes support. That's the rating we have in our data—meaning there's some evidence for a benefit, but more research is still needed to be fully confident.

This isn't a substitute for prescription diabetes medications; it's something you'd consider as an additional tool only under your doctor's guidance.

The evidence, ingredient by ingredient Ivy Gourd

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Ivy gourd leaf is generally well tolerated when taken by mouth. A small number of people report mild nausea, headache, or drowsiness.

Because the supplement doses used are less well studied than food amounts, there's a caution about blood-sugar effects—especially if you don't have diabetes. During pregnancy, there isn't enough safety information, so medicinal amounts are best avoided.

The same goes for breastfeeding—safety hasn't been established, so it's best to skip medicinal use while nursing. If you're pregnant or breastfeeding and interested in this product, talk with your doctor or pharmacist for personalized advice.

Side effects, ingredient by ingredient Ivy Gourd

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Ivy Gourd.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 86 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take any antidiabetes medication—insulin, metformin, sulfonylureas, or any other blood-sugar drug—you need to check the exact medication with your doctor or pharmacist before adding Coccinia. The risk is Moderate for low blood glucose when the effects combine.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

Coccinia may be worth a conversation if you're managing blood sugar and want an herbal option, but only with your doctor's approval—especially if you're already on diabetes medication. If you're pregnant, nursing, or taking any blood-sugar drugs, check with your doctor or pharmacist before starting.

This is a supplement, not a replacement for prescription treatment.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Coccinia, straight from the product label.

Brand Herbal Terra
Barcode (UPC) 7429523284217
Net contents 4 Fluid Ounce(s); 120 mL
Market status On market
Date entered into DSLD Sep 25, 2020
DSLD ID 234370
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Organic, Gluten Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Coccinia by Herbal Terra, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 mL
Maximum serving Sizes:
1 mL
Servings per container
120
UPC/BARCODE
7429523284217
IngredientAmount% DV
certified organic Coccinia dried fruit liquid extract970 mg--

Other ingredients: Menstruum

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Origin of plant material: Thailand.

Manufactured in the USA in an FDA registered facility

Sugar free

Dried herb/menstruum ratio: 1:3 Expertly extracted Laboratory tested 330 mg/1 mL Premium product Super concentrated liquid herbal extract

Non GMO

No artificial ingredients, GMO, gluten, color additives, fillers, preservatives or binders. Natural Gluten Free

Suggested/Recommended/Usage/Directions

Direction Shake well before use. Adults take up to 30 drops (1 mL, one full squeeze of the dropper bulb) in 3-4 fl. oz of juice or water up to 4 times a day. We recommend to seek expert medical advice before taking this or any other herbal supplements.

FDA Disclaimer Statement

Notice This product has not been evaluated by the FDA and is not intended to diagnose, treat, cure, or prevent any disease.

Precautions

Caution May have contraindications.

Do not use if you are allergic to any ingredients.

Consult a physician before using during pregnancy, if nursing, or if you are on any medications.

Keep out of the reach of children.

Storage

Store in a cool, dry, dark place.

Formula

Coccinia cordifolia

FDA Statement of Identity

Herbal Supplement

Seals/Symbols

Made in USA Made in an FDA registered facility Natural Gluten Free

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Coccinia by Herbal Terra label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Coccinia label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Coccinia by Herbal Terra

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 mL Dosage formLiquid Servings per container120 Amounts shown are per serving.

Certified organic Coccinia dried fruit liquid extract

Interacts with
86 drugs
970 mg per serving

Ivy gourd is a tropical vine widely eaten as a vegetable and used in traditional medicine, most often for blood sugar support. Early human research hi...

Certified organic Coccinia dried fruit liquid extract monograph & interactions

Other (inactive) ingredients: Menstruum. These complete the product’s ingredient list but are not active constituents.

Interaction report

Coccinia by Herbal Terra Drug Interactions

Want to check YOUR meds against Coccinia?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
86Drugs
86 Moderate

Ingredients driving the most interactions

certified organic Coccinia dried fruit liquid extract 86

Individual Drug Interactions

The ingredients in Coccinia interact with 86 drugs. Click any drug to see the details.

1 of the 1 ingredient in Coccinia interact with drugs. Each result below shows which ingredient is responsible. certified organic Coccinia dried fruit liquid extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Coccinia with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

certified organic Coccinia dried fruit liquid extract1 drug type · 86 drugs

Antidiabetes Drugs

Ivy gourd may lower blood glucose levels and might have additive effects when used with antidiabetes drugs. This might increase the risk of hypoglycemia in some patients. Monitor blood glucose levels closely.

Likelihood Probable Evidence A
certified organic Coccinia dried fruit liquid extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Coccinia, from the product label.

Herbal Terra

See all Herbal Terra products
Name
Herbal Terra
Pharmacist Counseling Corner

Coccinia by Herbal Terra: Common Questions

Does Coccinia by Herbal Terra interact with any medications?
Yes. Based on its ingredients, Coccinia has a known interaction with 86 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Coccinia contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will Coccinia lower my blood sugar if I don't have diabetes?
Ivy gourd can lower blood glucose levels, so yes, it may affect your blood sugar even if you don't take diabetes medication. Because supplement doses are less studied than food amounts, there's a caution about this effect in people without diabetes. Talk with your pharmacist or doctor before taking it.
What side effects might I notice?
Ivy gourd leaf is generally well tolerated, but some people report mild nausea, headache, or drowsiness. These are not common, but if you notice them, let your pharmacist know.
Can I take this while pregnant or breastfeeding?
No. There isn't enough safety data during pregnancy, so medicinal amounts are best avoided. Safety hasn't been established for breastfeeding either. Talk with your doctor or pharmacist if you're pregnant or nursing and interested in this product.
Does Coccinia actually work for diabetes?
The evidence suggests ivy gourd is possibly effective for diabetes, meaning there's some research support but we'd like to see more. It's not a replacement for prescription medications—think of it as something to discuss with your doctor as part of a broader approach.
What is ivy gourd?
Ivy gourd is a plant used traditionally in folk medicine, and this product delivers it as a concentrated liquid extract made from the dried fruit.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Coccinia is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Coccinia label
Go deeper

The Full Monographs Behind Coccinia’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Ivy Gourd

Interacts with 86 drugs

Ivy gourd is a tropical vine widely eaten as a vegetable and used in traditional medicine, most often for blood sugar support. Early human research hints it may modestly lower blood sugar, b...

Read the full Ivy Gourd monograph →
Sources

Sources & How We Checked

Coccinia's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 5 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Ivy Gourd 5 references
  1. Khan AK, AKhtar S, Mahtab H. Treatment of diabetes mellitus with Coccinia indica. Br Med J 1980;280:1044. PubMed
  2. Munasinghe MAAK, Abeysena C, Yaddehige IS, et al. Blood sugar lowering effect of Coccinia grandis (L.) J. Voight: path for a new drug for diabetes mellitus. Exp Diabetes Res 2011; doi: 10.1155/2011/978762.
  3. Venkateswaran, S. and Pari, L. Effect of Coccinia indica leaf extract on plasma antioxidants in streptozotocin- induced experimental diabetes in rats. Phytother.Res 2003;17(6):605-608.
  4. Kuriyan, R., Rajendran, R., Bantwal, G., and Kurpad, A. V. Effect of supplementation of Coccinia cordifolia extract on newly detected diabetic patients. Diabetes Care 2008;31(2):216-220.
  5. Wasana KGP, Attanayake AP, Weerarathna TP, Jayatilaka KAPW. Efficacy and safety of a herbal drug of Coccinia grandis (Linn.) Voigt in patients with type 2 diabetes mellitus: A double blind randomized placebo controlled clinical trial. Phytomedicine. 2021 PubMed

See these in context on the Ivy Gourd monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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