Interactions on record — worth a quick check against your medications. Based on 2 of 3 ingredients. Check your meds →
Dietary supplement

Sugar Balance Ingredients & Drug Interactions

by Organic India

Sugar Balance label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Sugar Balance against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Sugar Balance is a dietary supplement by Organic India with 3 active ingredients. Its ingredients are commonly taken for blood sugar support, digestive complaints, skin conditions.Based on those ingredients, 87 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Madagascar Periwinkle, Ivy Gourd Leaf Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Sugar Balance by Organic India

Ask about any prescription or over-the-counter medication and we check it for interactions with Sugar Balance by Organic India — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Sugar Balance by Organic India

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 3 of its 3 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains 3 active ingredients. Ivy gourd leaf extract and Madagascar periwinkle are both traditional plants used to support blood sugar management.

Great Bougainvillea rounds out the blend. The capsule shell is made from pullulan, an inactive ingredient.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: maintain healthy blood sugar and glucose metabolism.
  • We looked for evidence on: Diabetes, Blood sugar control, Glucose metabolism, Insulin sensitivity.
  • The strongest evidence on file: Ivy Gourd is rated "Possibly Effective" for Diabetes (Natural Medicines).

Ivy gourd leaf extract is rated possibly effective for diabetes support based on available evidence. Madagascar periwinkle and Great Bougainvillea don't have effectiveness ratings in our data, so we can't speak to how well they work for their intended purpose.

The evidence, ingredient by ingredient Ivy Gourd Madagascar Periwinkle

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Ivy gourd leaf is generally well tolerated as a food, though supplement doses haven't been as thoroughly studied. It may cause mild nausea, headache, or drowsiness in some people.

Madagascar periwinkle, however, is a concern: the raw plant contains toxic alkaloids and is not considered safe as a self-care supplement. It can trigger serious side effects including hallucinations, seizures, stomach upset, hair loss, dizziness, hearing problems, and blood cell changes.

Exposure to its airborne pollen can trigger allergic respiratory reactions in people with respiratory allergies. For pregnancy: there isn't enough safety data on ivy gourd in medicinal amounts, so it's best avoided.

Madagascar periwinkle is rated likely unsafe in pregnancy due to its toxic alkaloids. For breastfeeding: safety data on ivy gourd is insufficient, so avoid medicinal use; Madagascar periwinkle is rated likely unsafe and should be avoided.

Side effects, ingredient by ingredient Ivy Gourd Madagascar Periwinkle

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 2 matched ingredients can interact with medications — Madagascar Periwinkle, Ivy Gourd.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications; lithium.
  • For scale: 87 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take Sugar Balance, check with your pharmacist if you're on any antidiabetes drugs — insulin, metformin, sulfonylureas, and others all carry a Moderate risk of low blood sugar when combined with this product. If you take lithium for mood disorders, that's also Moderate risk; lithium levels may climb.

These aren't deal-breakers, but they do need monitoring and possibly a dose adjustment.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This product combines plants traditionally used for blood sugar support, but it's not for everyone. If you take diabetes medication or lithium, you need to talk with your pharmacist or doctor before starting — the blood sugar and lithium interactions are real risks.

Pregnant or breastfeeding women should avoid it. The Madagascar periwinkle component carries serious safety flags that make this product worth a careful conversation with your healthcare provider.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Nov 22, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Sugar Balance, straight from the product label.

Brand Organic India
Barcode (UPC) 851469000748
Net contents 90 Veg Cap(s)
Market status On market
Date entered into DSLD Nov 22, 2023
DSLD ID 300147
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Kosher, Organic, Halal
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Sugar Balance by Organic India, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
45
UPC/BARCODE
851469000748
IngredientAmount% DV
Ivy Gourd Leaf Extract400 mg--
Great Bougainvillea600 mg--
Madagascar Periwinkle40 mg--

Other ingredients: Pullulan

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

At the heart of Organic India is our commitment to be a living embodiment of love an consciousness in action. Whole herb solutions grown sustainably by small family farmers using regenerative organic agriculture. Healthy Conscious Living

Mfg. Lic. No. A-2755

Formula

Sugar Balance is a clinically studied proprietary formula of Ayurvedic herbs, that helps maintain blood sugar levels already in a healthy range and supports glucose metabolism for heart health, hormone and weight balance, and healthy circulation.

Jaimat Ulama Halal Foundation Mumbai India 0854

OU (Kosher)

Suggested/Recommended/Usage/Directions

Suggested Use: 2 capsules twice daily with food and water.

Precautions

Talk to your healthcare professional before using, especially if you have a health condition, take medication, are pregnant, or are nursing.

Warning: Reproductive Harm - www.P65Warnings.ca.gov

Formulation

Vegan Vegetarian

Gluten free

Healthy Glucose Metabolism

USDA Organic

Non GMO Project Verified nongmoproject.org

Certified Organic by Control Union-CU 801983. Product produced and processed according to NPOP standard of India & USDA-NOP www.controlunion.com

Product of India for export to USA only

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Seals/Symbols

Clinically Tested

USDA Organic Non GMO Project Verified nongmoproject.org Certified B Corporations Control Union Certified NPOP/NAB/0010

Jaimat Ulama Halal Foundation Mumbai India 0854 OU (Kosher)

FDA Statement of Identity

Herbal Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Sugar Balance by Organic India label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Sugar Balance label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Sugar Balance by Organic India

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container45 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Ivy Gourd Leaf Extract

Interacts with
86 drugs
400 mg per serving

Ivy gourd is a tropical vine widely eaten as a vegetable and used in traditional medicine, most often for blood sugar support. Early human research hi...

Ivy Gourd Leaf Extract monograph & interactions

Great Bougainvillea

600 mg per serving

Madagascar Periwinkle

Interacts with
87 drugs
40 mg per serving

Madagascar periwinkle is a flowering plant famous as the natural source of important chemotherapy drugs (vincristine and vinblastine), but the raw pla...

Madagascar Periwinkle monograph & interactions

Other (inactive) ingredients: Pullulan. These complete the product’s ingredient list but are not active constituents.

Interaction report

Sugar Balance by Organic India Drug Interactions

Want to check YOUR meds against Sugar Balance?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
87Drugs
87 Moderate

Ingredients driving the most interactions

Madagascar Periwinkle 87
Ivy Gourd Leaf Extract 86

Individual Drug Interactions

The ingredients in Sugar Balance interact with 87 drugs. Click any drug to see the details.

2 of the 3 ingredients in Sugar Balance interact with drugs. Each result below shows which ingredient is responsible. Madagascar Periwinkle Ivy Gourd Leaf Extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Sugar Balance with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Madagascar Periwinkle2 drug types · 87 drugs

Antidiabetes Drugs

Animal research shows that Madagascar periwinkle lowers blood glucose levels in diabetic rats. Theoretically, using Madagascar periwinkle in combination with antidiabetes drugs might increase the risk of hypoglycemia; monitor blood glucose closely.

Likelihood Possible Evidence D
Lithium

Madagascar periwinkle is thought to have diuretic properties. Theoretically, due to these potential diuretic effects, Madagascar periwinkle might reduce excretion and increase levels of lithium. The dose of lithium might need to be decreased.

Likelihood Possible Evidence D
Madagascar Periwinkle full monograph & interactions

Ivy Gourd Leaf Extract1 drug type · 86 drugs

Antidiabetes Drugs

Ivy gourd may lower blood glucose levels and might have additive effects when used with antidiabetes drugs. This might increase the risk of hypoglycemia in some patients. Monitor blood glucose levels closely.

Likelihood Probable Evidence A
Ivy Gourd Leaf Extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Sugar Balance, from the product label.

Organic India

See all Organic India products
Name
Organic India USA
City
Boulder
State
CO
ZipCode
80302
Phone Number
1-888-550-8332
Web Address
organicindiaUSA.com
Pharmacist Counseling Corner

Sugar Balance by Organic India: Common Questions

Does Sugar Balance by Organic India interact with any medications?
Yes. Based on its ingredients, Sugar Balance has a known interaction with 87 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Sugar Balance contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm on insulin or metformin?
Not without checking with your pharmacist or doctor first. Both ivy gourd and Madagascar periwinkle can lower blood glucose, and combining them with diabetes medication raises the risk of dangerously low blood sugar. You'd need to monitor your glucose closely and possibly adjust your insulin or metformin dose.
What side effects might I notice?
Ivy gourd leaf may cause mild nausea, headache, or drowsiness. Madagascar periwinkle is a bigger concern — it can cause serious effects like hallucinations, seizures, stomach upset, hair loss, and blood cell changes. Some people also react to its airborne pollen with respiratory symptoms.
Is it safe to take while pregnant?
No. Madagascar periwinkle is rated likely unsafe in pregnancy because of its toxic alkaloids. Ivy gourd doesn't have enough safety data in medicinal amounts, so it's best avoided too. Talk with your doctor about alternatives.
Is it safe while breastfeeding?
No. Madagascar periwinkle is rated likely unsafe while breastfeeding. Ivy gourd's safety isn't well established in nursing either, so it's best to avoid it. Your doctor or pharmacist can suggest other options.
Does ivy gourd actually work for blood sugar?
Ivy gourd leaf is rated possibly effective for diabetes support based on the evidence we have. That means there's some backing, but it's not a proven cure — it works best alongside your regular diabetes care and close glucose monitoring.
What are the inactive ingredients?
The capsule is made from pullulan, a film-forming polymer. That's the only inactive ingredient listed.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Sugar Balance label
Go deeper

The Full Monographs Behind Sugar Balance’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Ivy Gourd

Interacts with 86 drugs

Ivy gourd is a tropical vine widely eaten as a vegetable and used in traditional medicine, most often for blood sugar support. Early human research hints it may modestly lower blood sugar, b...

Read the full Ivy Gourd monograph → Herb & supplement monograph

Madagascar Periwinkle

Interacts with 87 drugs

Madagascar periwinkle is a flowering plant famous as the natural source of important chemotherapy drugs (vincristine and vinblastine), but the raw plant itself is toxic and not safe to use a...

Read the full Madagascar Periwinkle monograph →
Sources

Sources & How We Checked

Sugar Balance's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 11 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Ivy Gourd 5 references
  1. Khan AK, AKhtar S, Mahtab H. Treatment of diabetes mellitus with Coccinia indica. Br Med J 1980;280:1044. PubMed
  2. Munasinghe MAAK, Abeysena C, Yaddehige IS, et al. Blood sugar lowering effect of Coccinia grandis (L.) J. Voight: path for a new drug for diabetes mellitus. Exp Diabetes Res 2011; doi: 10.1155/2011/978762.
  3. Venkateswaran, S. and Pari, L. Effect of Coccinia indica leaf extract on plasma antioxidants in streptozotocin- induced experimental diabetes in rats. Phytother.Res 2003;17(6):605-608.
  4. Kuriyan, R., Rajendran, R., Bantwal, G., and Kurpad, A. V. Effect of supplementation of Coccinia cordifolia extract on newly detected diabetic patients. Diabetes Care 2008;31(2):216-220.
  5. Wasana KGP, Attanayake AP, Weerarathna TP, Jayatilaka KAPW. Efficacy and safety of a herbal drug of Coccinia grandis (Linn.) Voigt in patients with type 2 diabetes mellitus: A double blind randomized placebo controlled clinical trial. Phytomedicine. 2021 PubMed

See these in context on the Ivy Gourd monograph →

Madagascar Periwinkle 6 references
  1. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
  2. McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
  3. Ellenhorn MJ, et al. Ellenhorn's Medical Toxicology: Diagnoses and Treatment of Human Poisoning. 2nd ed. Baltimore, MD: Williams & Wilkins, 1997.
  4. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  5. Ghosh D, Roy I, Chanda S, Gupta-Bhattacharya S. Allergy to periwinkle pollen (Catharanthus roseus G. Don.). Ann Agric Environ Med. 2007;14(1):39-43.
  6. Oguntibeju OO, Aboua Y, Goboza M. Vindoline-A natural product from catharanthus roseus reduces hyperlipidemia and renal pathophysiology in experimental type 2 diabetes. Biomedicines. 2019 Aug 13;7(3):59. PubMed

See these in context on the Madagascar Periwinkle monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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