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Dietary supplement

Coco Hemp Ingredients & Drug Interactions

by Swanson EFAs

Softgel Capsule Category: Fat/fatty Acid
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Coco Hemp is a dietary supplement by Swanson EFAs with 2 active ingredients. Its ingredients are commonly taken for plant-based protein source, heart health support, skin and hair health.Based on those ingredients, 1,018 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are organic Hemp seed Oil, organic Coconut Oil. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Coco Hemp by Swanson EFAs

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains 2 active ingredients: organic hemp seed oil and organic coconut oil. Hemp seed oil is a source of essential fatty acids derived from the seeds of the hemp plant.

Coconut oil is extracted from the meat of coconuts and is also rich in fatty acids. The softgel capsule itself is made from gelatin, glycerin, and purified water.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: Superior essential fatty acids.
  • We looked for evidence on: Hypercholesterolemia, Familial hypercholesterolemia, Hypertension, Joint pain, Osteoarthritis, Pain (chronic) — and 3 related terms.
  • The closest evidence on file: Coconut is rated "Insufficient Reliable Evidence To Rate" for Hypercholesterolemia (Natural Medicines).
  • Also on file: Hemp is rated "Insufficient Reliable Evidence To Rate" for Atopic dermatitis (eczema), Familial hypercholesterolemia, Hypertension, Osteoarthritis, and more.

The evidence we hold doesn't establish that either ingredient works for the conditions listed—constipation, eczema, high cholesterol, diabetes, obesity, and lichen planus all have insufficient reliable evidence to rate hemp or coconut. That doesn't mean they don't work; it means the data we have isn't strong enough to say one way or the other.

If you're considering this product for a specific health concern, that's a good conversation to have with your doctor or pharmacist.

The evidence, ingredient by ingredient Hemp Coconut

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Hemp seed oil and coconut oil are generally well tolerated in food amounts. When taken as concentrated supplements in larger amounts, though, the safety data is limited.

Allergic reactions are the main concern with both: hemp seed allergies are uncommon but can range from hives to anaphylaxis and facial swelling, and coconut allergies—which are treated like tree nut allergies in the US—can trigger similar reactions. Rare cases of liver problems and serious cardiac symptoms (long QT, abnormal heart rhythm) have been reported with hemp products, though these are very uncommon.

Because safety data on concentrated hemp and coconut supplements is limited compared to food amounts, proceed with caution and talk with your doctor if you have a history of allergies or liver problems.

Side effects, ingredient by ingredient Hemp Coconut

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 2 matched ingredients can interact with medications — Coconut, Hemp.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications.
  • For scale: 1,019 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your doctor or pharmacist before taking this product if you're on estrogen therapy or birth control pills (hemp may interfere with them—Moderate concern). Also flag any blood pressure medications, ACE inhibitors, blood thinners, antiplatelet drugs like aspirin, diabetes medications, or drugs metabolized by CYP1A2 or CYP3A4 enzymes—all Minor interactions, but worth confirming your specific medications won't be affected.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

This product might appeal to you if you're looking for an omega-3 and fatty-acid supplement from plant-based sources. If you take any medications—especially hormone therapy, blood pressure drugs, blood thinners, or diabetes medications—check your exact drugs with your pharmacist or doctor before starting.

Because the safety data on concentrated hemp and coconut supplements is limited, it's worth having that conversation too.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Sep 24, 2019.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Coco Hemp, straight from the product label.

Brand Swanson EFAs
Barcode (UPC) 087614170916
Net contents 60 Softgel(s)
Market status On market
Date entered into DSLD Sep 24, 2019
DSLD ID 203481
Product type Fat/fatty Acid
Supplement form Softgel Capsule
Dietary claims / uses Nutrient, All Other
Intended target group(s) Adult (18 - 50 Years), Organic
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Coco Hemp by Swanson EFAs, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Softgel(s)
Maximum serving Sizes:
1 Softgel(s)
UPC/BARCODE
087614170916
IngredientAmount% DV
Calories10 Calorie(s)--
Saturated Fat1 Gram(s)5%
Trans Fat0 Gram(s)--
Total Fat1 Gram(s)1%
organic Hemp seed Oil500 mg--
organic Coconut Oil500 mg--

Other ingredients: Gelatin, Glycerin, purified Water

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Superior essential fatty acids

Made in Canada To reorder, call toll free 1-800-437-4148 or visit our website at www.swansonvitamins.com

Formula

Made with organic Coco Hemp Coconut Oil + Hemp Seed Oil

Contains tree nuts (coconuts).

FDA Statement of Identity

Dietary Supplement

Seals/Symbols

Guaranteed purity & potency

Precautions

Do not use if seal is broken.

Keep out of reach of children.

Contains tree nuts (coconuts).

Storage

Store in a cool, dry place. Do not refrigerate.

Suggested/Recommended/Usage/Directions

Suggested use: As a dietary supplement, take one softgel one to three times per day with water.

Formulation

Certified Organic by Minnesota Crop Improvement Association (MCIA), St. Paul, MN 5510

General

SWE091 Rev 0 10 16 18

See for yourself

Coco Hemp by Swanson EFAs label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Coco Hemp by Swanson EFAs

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Softgel(s) Dosage formSoftgel Capsule Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Organic Hemp seed Oil

Interacts with
938 drugs
500 mg per serving

Hemp seeds and hemp seed oil are nutritious foods rich in protein, fiber, and healthy omega-3 and omega-6 fatty acids, and they are generally safe for...

Organic Hemp seed Oil monograph & interactions

Organic Coconut Oil

Interacts with
86 drugs
500 mg per serving

Coconut is a nutritious tropical food enjoyed as oil, water, milk, and flesh, and it is generally safe to eat in normal food amounts. While some uses...

Organic Coconut Oil monograph & interactions

Other (inactive) ingredients: Gelatin, Glycerin, Purified Water. These complete the product’s ingredient list but are not active constituents.

Interaction report

Coco Hemp by Swanson EFAs Drug Interactions

Want to check YOUR meds against Coco Hemp?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
1,018Drugs
41 Moderate 977 Minor

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Coco Hemp with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

organic Hemp seed Oil6 drug types · 938 drugs

Estrogens

Theoretically, hemp might interfere with hormone therapy due to its estrogenic effects.
In an ovariectomized animal model, a diet containing hemp seed 1%, 2%, or 10% resulted in normalized plasma levels of 17-beta-estradiol. The mechanism of action for this effect is unclear.

Likelihood Possible Evidence D
Ace Inhibitors (Aceis)

Theoretically, consuming hemp seed protein isolate with ACE inhibitors might have additive effects and increase the risk of hypotension.
Hemp seed protein hydrolysate has shown ACE inhibitor-like effects in a hypertensive animal model. However, hempseed oil consumption does not seem to reduce blood pressure in humans. Until more is known, monitor blood pressure and potassium levels.

Likelihood Unlikely Evidence D
Anticoagulant/Antiplatelet Drugs

Theoretically, hemp seed might increase the risk of bleeding when used concomitantly with anticoagulant/antiplatelet drugs.
In animal research, hemp seed at 5% of the diet inhibits platelet aggregation in vitro. However, in human research, taking hemp seed oil 2 grams daily for 12 weeks does not inhibit the aggregation of platelets in vitro.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, hemp seed protein may have additive effects with antihypertensive drugs.
In a hypertensive animal model, hemp seed protein hydrolysate reduced systolic blood pressure by a mechanism possibly involving the inhibition of renin and angiotensin converting enzyme (ACE) activities. However, there was no effect of hemp seed protein on blood pressure in normotensive animals. Furthermore, hempseed oil consumption does not seem to reduce blood pressure in humans.

Likelihood Unlikely Evidence D
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, hemp might decrease the levels and clinical effects of CYP1A2 substrates.
In vitro research shows that hemp induces CYP1A2 enzymes.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, hemp might decrease the levels and clinical effects of CYP3A4 substrates.
In vitro research shows that hemp induces CYP3A4 enzymes.

Likelihood Possible Evidence D

organic Coconut Oil1 drug type · 86 drugs

Antidiabetes Drugs

Theoretically, taking coconut with antidiabetes drugs might increase the risk of hypoglycemia.
Animal research suggests that coconut milk might increase insulin levels and/or decrease blood glucose levels.

Likelihood Unlikely Evidence D
The maker

Brand information

Manufacturer and brand details for Coco Hemp, from the product label.

Swanson EFAs

See all Swanson EFAs products
Name
Swanson Health Products
City
Fargo
State
ND
ZipCode
58104
Phone Number
1-800-437-4148
Web Address
www.swansonvitamins.com
Pharmacist Counseling Corner

Coco Hemp by Swanson EFAs: Common Questions

Does Coco Hemp by Swanson EFAs interact with any medications?
Yes. Based on its ingredients, Coco Hemp has a known interaction with 1,018 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Coco Hemp contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant or breastfeeding?
Coconut oil is rated likely safe in pregnancy and lactation. However, there isn't enough data on file for hemp seed oil in pregnancy and breastfeeding to say either way. Talk with your doctor or pharmacist for personalized advice before taking this product while pregnant or nursing.
What are the side effects?
Both hemp seed oil and coconut oil are generally well tolerated. The main adverse effects to watch for are allergic reactions—hives, facial swelling, shortness of breath, or in rare cases anaphylaxis—especially if you have a known allergy to tree nuts or hemp seed. Serious effects are very uncommon.
Does this help with cholesterol or blood sugar?
The evidence we hold shows insufficient reliable evidence to rate either hemp or coconut for high cholesterol or diabetes. That means the data isn't strong enough to say whether they work for those conditions.
Is this product tested for quality?
The product facts we have don't include testing or certification details, so I can't speak to that. You may want to check the label or contact the manufacturer directly for information on third-party testing or quality standards.
Can I take this in large amounts?
Hemp seed oil and coconut oil are generally well tolerated in food amounts and larger supplement doses of coconut oil seem okay too. However, concentrated hemp extracts and supplements are less studied, so caution is advised at higher doses. Your doctor or pharmacist can help you figure out what's right for you.
What's the difference between this and just eating hemp seeds or coconut?
Food amounts of hemp seeds and coconut are well tolerated and studied. This softgel delivers concentrated oils in supplement form, and concentrated hemp supplements in particular are less studied than the whole food, so the safety profile isn't quite as clear.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Coco Hemp is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Coco Hemp label
Sources

Sources & How We Checked

Coco Hemp's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 22 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Hemp 12 references
  1. Kaul N, Kreml R, Austria JA, et al. A comparison of fish oil, flaxseed oil and hempseed oil supplementation on selected parameters of cardiovascular health in healthy volunteers. J Am Coll Nutr 2008;27:51-8. PubMed
  2. Saberivand A, Karimi I, Becker LA, et al. The effects of Cannabis sativa L. seed (hempseed) in the ovariectomized rat model of menopause. Methods Find Exp Clin Pharmacol. 2010;32(7):467-73. PubMed
  3. Girgih AT, Alashi A, He R, Malomo S, Aluko RE. Preventive and treatment effects of a hemp seed (Cannabis sativa L.) meal protein hydrolysate against high blood pressure in spontaneously hypertensive rats. Eur J Nutr. 2014;53(5):1237-46. PubMed
  4. Richard MN, Ganguly R, Steigerwald SN, Al-Khalifa A, Pierce GN. Dietary hempseed reduces platelet aggregation. J Thromb Haemost. 2007;5(2):424-5. PubMed
  5. Stadtmauer G, Beyer K, Bardina L, Sicherer SH. Anaphylaxis to ingestion of hempseed (Cannabis sativa). J Allergy Clin Immunol. 2003;112(1):216-7. PubMed
  6. Del Bo' C, Deon V, Abello F, et al. Eight-week hempseed oil intervention improves the fatty acid composition of erythrocyte phospholipids and the omega-3 index, but does not affect the lipid profile in children and adolescents with primary hyperlipidemia. PubMed
  7. Alkhammash S, Tsui H, Thomson DMP. Cannabis and hemp seed allergy. J Allergy Clin Immunol Pract. 2019;7(7):2429-2430.e1. PubMed
  8. Stokes JR, Hartel R, Ford LB, Casale TB. Cannabis (hemp) positive skin tests and respiratory symptoms. Ann Allergy Asthma Immunol. 2000;85(3):238-40. PubMed
  9. Déléaval M, Burri H, Bakelants E. Harmless herbs? A case report of acquired long QT syndrome and torsades de pointes in a patient taking herbal supplements. HeartRhythm Case Rep 2022;8(5):309-12. PubMed
  10. Singh M, Sehgal M, Yacoub M, et al. Severe liver dysfunction in a toddler receiving nonprescription phytocannabinoid. J Am Pharm Assoc (2003) 2022;62(4):1438-1440. PubMed
  11. Clark E, Nilsson U, Samaran Q, Raison-Peyron N. Allergic contact dermatitis from Cannabis sativa (hemp) seed oil. Contact Dermatitis 2022;87(3):292-293.
  12. Haron MH, Dale O, Martin K, et al. Evaluation of the Herb-Drug Interaction Potential of Commonly Used Botanicals on the US Market with Regard to PXR- and AhR-Mediated Influences on CYP3A4 and CYP1A2. J Diet Suppl 2022. PubMed

See these in context on the Hemp monograph →

Coconut 10 references
  1. Teuber SS, Peterson WR. Systemic allergic reaction to coconut (Cocos nucifera) in 2 subjects with hypersensitivity to tree nut and demonstration of cross-reactivity to legumin-like seed storage proteins: new coconut and walnut food allergens. J Allergy Cl PubMed
  2. Rosado A, Fernandez-Rivas M, Gonzalez-Mancebo E, et al. Anaphylaxis to coconut. Allergy 2002;57(2):182-3. PubMed
  3. Karmakar PR, Das A, Chatterjee BP. Placebo-controlled immunotherapy with Cocos nucifera pollen extract. Int Arch Allergy Immunol 1994;103(2):194-201. PubMed
  4. Anagnostou K. Coconut Allergy Revisited. Children (Basel). 2017;4(10). pii: E85. PubMed
  5. Cifuentes L, Mistrello G, Amato S, et al. Identification of cross-reactivity between buckwheat and coconut. Ann Allergy Asthma Immunol. 2015;115(6):530-2. PubMed
  6. Michavila Gomez A, Amat Bou M, Gonzalez Cortés MV, Segura Navas L, Moreno Palanques MA, Bartolomé B. Coconut anaphylaxis: Case report and review. Allergol Immunopathol (Madr). 2015;43(2):219-20. PubMed
  7. 21CFR170.3. U.S. Food and Drug Administration Department of Health and Human Services. Updated April 1, 2017. https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=170.3
  8. Alatawi KA, Alshubaily FA. Coconut products alleviate hyperglycaemic, hyperlipidimic and nephropathy indices in streptozotocin-induced diabetic wistar rats. Saudi J Biol Sci. 2021;28(8):4224-4231. PubMed
  9. Kruse L, Lor J, Yousif R, Pongracic JA, Fishbein AB. Coconut allergy: Characteristics of reactions and diagnostic predictors in a pediatric tertiary care center. Ann Allergy Asthma Immunol 2021;126(5):562-568.
  10. Pathmanandavel K, Kaur N, Joshi P, Ford LS. Anaphylaxis and allergy to coconut: An Australian pediatric case series. J Allergy Clin Immunol Pract 2020;8(10):3657-3659. PubMed

See these in context on the Coconut monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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