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Dietary supplement

Colloidal Silver Plus Ingredients & Drug Interactions

by Village Vitality

Colloidal Silver Plus label
See full label image
Liquid Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Colloidal Silver Plus against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Colloidal Silver Plus is a dietary supplement by Village Vitality with 3 active ingredients. Its ingredients are commonly taken for heart health, high blood pressure, high cholesterol.Based on those ingredients, 208 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Wild Oregano Oil. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Colloidal Silver Plus by Village Vitality

Ask about any prescription or over-the-counter medication and we check it for interactions with Colloidal Silver Plus by Village Vitality — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Colloidal Silver Plus by Village Vitality

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 12, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 3 active ingredients.
  • “Proprietary Blend” is a proprietary blend — the label doesn't break down how much of each component you get.

Colloidal Silver Plus contains 3 active ingredients. Wild Oregano Oil is included as an herbal extract.

Olive and Colloidal Silver round out the formula. The product also contains inactive ingredients: deionized water, grain alcohol, and soy lecithin as excipients.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: Bio protectant.
  • We looked for evidence on: Wound healing, Antimicrobial support, Skin health, Immune support.
  • The closest evidence on file: Oregano is rated "Insufficient Reliable Evidence To Rate" for Wound healing (Natural Medicines).
  • Also on file: Colloidal Silver is rated "Insufficient Reliable Evidence To Rate" for Wound healing.

The evidence supporting these ingredients is limited. Olive shows insufficient reliable evidence for osteoporosis, heartburn (dyspepsia), exercise-induced respiratory infections, shingles, influenza, and osteoarthritis.

Colloidal Silver is rated possibly ineffective for sinus infections (rhinosinusitis) and has insufficient evidence for hay fever, cancer, and COPD. Wild Oregano Oil similarly has insufficient evidence for acne, bronchitis, asthma, headache, and upper respiratory infections.

None of these uses have established proof in the data we hold.

The evidence, ingredient by ingredient Olive Colloidal Silver Oregano

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Olive and olive oil are safe as foods, but concentrated supplements are less well studied — stick with food amounts or talk to your doctor before using concentrated supplements. Wild Oregano Oil is well tolerated in typical food amounts; at larger medicinal doses, gastrointestinal upset is most common, and rare systemic allergic reactions including anaphylaxis have been reported in sensitive people.

Colloidal Silver carries serious safety warnings. Health authorities discourage oral use because it can cause lasting harm — cases include severe anemia, seizures, and bone marrow damage from long-term intake.

It must be avoided during pregnancy and while breastfeeding, as silver can accumulate in the body and harm the developing baby or nursing infant.

Side effects, ingredient by ingredient Olive Colloidal Silver Oregano

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 3 matched ingredients can interact with medications — Oregano.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications.
  • For scale: 208 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check your medications against this product if you take blood thinners (Moderate interaction with oregano) or diabetes drugs (Moderate interaction with oregano). No other medication interactions are documented for the ingredients we could check.

Your pharmacist can search your exact drugs on this page.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

This product combines three ingredients with limited evidence of effectiveness. If you take blood thinners, antiplatelet drugs, or diabetes medications, check with your pharmacist first — Wild Oregano Oil may affect them.

The bigger concern here is Colloidal Silver: health authorities discourage its oral use due to serious potential harm, and it's unsafe in pregnancy and while breastfeeding. Talk to your pharmacist about whether this product makes sense for you.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Mar 24, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Colloidal Silver Plus, straight from the product label.

Brand Village Vitality
Barcode (UPC) 788332089510
Net contents 1 Fluid Ounce(s); 30 mL
Market status On market
Date entered into DSLD Mar 24, 2020
DSLD ID 215507
Product type Other Combinations
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Colloidal Silver Plus by Village Vitality, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 mL
Maximum serving Sizes:
2 mL
Servings per container
15
UPC/BARCODE
788332089510
IngredientAmount% DV
Olive0 NP--
Proprietary Blend0 NP--
Colloidal Silver0 NP--
Wild Oregano Oil0 NP--

Other ingredients: deionized Water, Grain Alcohol, Soy Lecithin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested Use: 60 drops, 1-2 times per day in water. Repeat as needed, or as directed by your health care professional. Shake well before using as separation is normal.

Precautions

Warning: A slight warming sensation is normal. Excessive amounts of silver taken over time can cause argyria, discoloration of the skin.

Keep out of the reach of children.

Formulation

Bio protectant

FDA Statement of Identity

Dietary Supplement

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Colloidal Silver Plus by Village Vitality label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Colloidal Silver Plus label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Colloidal Silver Plus by Village Vitality

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 mL Dosage formLiquid Servings per container15 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Proprietary Blend

0 NP per serving

Other (inactive) ingredients: Deionized Water, Grain Alcohol, Soy Lecithin. These complete the product’s ingredient list but are not active constituents.

Interaction report

Colloidal Silver Plus by Village Vitality Drug Interactions

Want to check YOUR meds against Colloidal Silver Plus?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
208Drugs
208 Moderate

Ingredients driving the most interactions

Wild Oregano Oil 208

Individual Drug Interactions

The ingredients in Colloidal Silver Plus interact with 208 drugs. Click any drug to see the details.

1 of the 3 ingredients in Colloidal Silver Plus interact with drugs. Each result below shows which ingredient is responsible. Wild Oregano Oil

Each ingredient & the kinds of drugs it affects

For each ingredient in Colloidal Silver Plus with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Wild Oregano Oil2 drug types · 208 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, oregano might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
In vitro research shows that aristolochic acid isolated from oregano leaves has antithrombin activity. It has also been reported that oregano oil inhibits arachidonic acid-induced, and ADP-induced, platelet aggregation.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, oregano might increase the risk for hypoglycemia when taken with antidiabetes drugs.
In vitro and animal research shows that oregano extracts might lower blood glucose levels.

Likelihood Possible Evidence D
Wild Oregano Oil full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Colloidal Silver Plus, from the product label.

Village Vitality

See all Village Vitality products
Name
Village Vitality LLC
Street Address
79 Tinker St. Floor 2
City
Woodstock
State
NY
ZipCode
12498
Pharmacist Counseling Corner

Colloidal Silver Plus by Village Vitality: Common Questions

Does Colloidal Silver Plus by Village Vitality interact with any medications?
Yes. Based on its ingredients, Colloidal Silver Plus has a known interaction with 208 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Colloidal Silver Plus contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is Colloidal Silver Plus safe to take while I'm pregnant or breastfeeding?
No. Colloidal Silver, one of the active ingredients, is rated unsafe in pregnancy because silver can build up in your body and harm the baby. It should also be avoided while breastfeeding since silver may pass to your infant and safety hasn't been established. Wild Oregano Oil is advised against in medicinal amounts during pregnancy, though food amounts are likely fine. Avoid this product and talk with your doctor about safer alternatives.
What's the most common side effect I might experience?
If you tolerate the other ingredients, gastrointestinal upset (stomach discomfort) from Wild Oregano Oil is most commonly reported when used in larger amounts. Olive may cause headache or stomach discomfort. Most people taking food-like amounts tolerate these ingredients well.
Can this product actually help with infections or respiratory issues?
The evidence for these uses is weak. Colloidal Silver is rated possibly ineffective for sinus infections, and the other ingredients have insufficient evidence for bronchitis, asthma, upper respiratory infections, or similar conditions in our data. Health authorities also discourage colloidal silver's oral use due to safety concerns.
Why does the label mention Colloidal Silver if it's discouraged?
Colloidal Silver is still sold in supplements, but health authorities and our safety data flag serious risks: cases of severe anemia, seizures, and bone marrow damage have been reported with long-term use. It's a red-flag ingredient you should discuss with your pharmacist before using.
Is there anything else in this product besides the active ingredients?
Yes — the product contains deionized water, grain alcohol, and soy lecithin as inactive ingredients (excipients that help deliver the actives). If you have a soy allergy, note the soy lecithin.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Colloidal Silver Plus label
Go deeper

The Full Monographs Behind Colloidal Silver Plus’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Olive

Olive comes from the same tree that gives us olives and olive oil, and its leaf and fruit contain antioxidant compounds like oleuropein and hydroxytyrosol. Olive oil as part of a Mediterrane...

Read the full Olive monograph → Herb & supplement monograph

Colloidal Silver

Colloidal silver is a liquid product containing tiny silver particles that is marketed for infections and immune support, but there is no reliable scientific evidence that it is safe or effe...

Read the full Colloidal Silver monograph → Herb & supplement monograph

Oregano

Interacts with 208 drugs

Oregano is a common Mediterranean cooking herb that is also sold as a concentrated oil or supplement, often standardized for a compound called carvacrol. While lab studies suggest it may hav...

Read the full Oregano monograph →
Sources

Sources & How We Checked

Colloidal Silver Plus's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 32 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Olive 2 references
  1. Liccardi G, D'Amato M, D'Amato G. Oleaceae pollinosis: a review. Int Arch Allergy Immunol 1996;111:210-7. PubMed
  2. Somerville V, Moore R, Braakhuis A. The effect of olive leaf extract on upper respiratory illness in high school athletes: A randomised control trial. Nutrients. 2019;11(2). pii: E358. PubMed

See these in context on the Olive monograph →

Colloidal Silver 18 references
  1. Fung MC, Bowen DL. Silver products for medical indications: risk-benefit assessment. J Toxicol Clin Toxicol 1996;34:119-26. PubMed
  2. Fung MC, Weintraub M, Bowen DL. Colloidal silver proteins marketed as health supplements. JAMA 1995;274:1196-7. PubMed
  3. Fung MC, Weintraub M, Bowen DL. Colloidal silver proteins marketed as health supplements. JAMA 1995;274:1196-7. PubMed
  4. Gulbranson SH, Hud JA, Hansen RC. Argyria following the use of dietary supplements containing colloidal silver protein. Cutis 2000;66:373-4.
  5. Hori K, Martin TG, Rainey P, Robertson WO. Believe it or not--silver still poisons! Vet Hum Toxicol 2002;44:291-2..
  6. McKenna JK, Hull CM, Zone JJ. Argyria associated with colloidal silver supplementation. Int J Dermatol 2003;42:549.. PubMed
  7. Cohen LE, Spurlock R, Salem A, Mercado E. Argyria in the silver state. Federal Practitioner 2004;April:9-17.
  8. Mirsattari, S. M., Hammond, R. R., Sharpe, M. D., Leung, F. Y., and Young, G. B. Myoclonic status epilepticus following repeated oral ingestion of colloidal silver. Neurology 4-27-2004;62(8):1408-1410. PubMed
  9. Stepien, K. M., Morris, R., Brown, S., Taylor, A., and Morgan, L. Unintentional silver intoxication following self-medication: an unusual case of corticobasal degeneration. Ann Clin Biochem. 2009;46(Pt 6):520-522. PubMed
  10. Griffith RD, Simmons BJ, Yazdani Abyaneh MA, Bray FN, Falto-Aizpurua LA, Nouri K. Colloidal Silver: Dangerous and Readily Available. JAMA Dermatol. 2015;151(6):667-8.
  11. Park SW, Shin HT, Lee KT, Lee DY. Medical concern for colloidal silver supplementation: agyria of the nail and face. Ann Dermatol. 2013;25(1):111-2.
  12. Butzmann CM, K Technau-Hafsi, Bross F. "Silver man" argyria of the skin after ingestion of a colloidal silver solution. J Dtsch Dermatol Ges. 2015;13(10):1030-2. PubMed
  13. Hadrup N, Lam HR. Oral toxicity of silver ions, silver nanoparticles and colloidal silver-- a review. Regul Toxicol Pharmacol. 2014;68(1):1-7. PubMed
  14. Natelson EA, Baker KR, Pyatt DW. Anemia and leukopenia following intravenous colloidal silver infusions-Clinical and hematological features, unique peripheral blood film appearance and effective therapy with supplemental oral copper and apheresis. Clin Ca PubMed
  15. Tobarran N, Hieger MA. Acute silver toxicity from colloidal silver overdose. Am J Ther. 2019. PubMed
  16. Keung YK, Wang T, Hong-Lung Hu E. Acute myeloid leukemia with complex cytogenetic abnormalities associated with long-term use of oral colloidal silver as nutritional supplement - Case report and review of literature. J Oncol Pharm Pract. 2020;26(1):212-21 PubMed
  17. Hu D, Yuen C. Seizures Following Self-Medication With Colloidal Silver: A Case Report. Hosp Pharm 2023;58(4):350-352. PubMed
  18. Stjernbrandt A. Colloidal silver ingestion and severe anemia - A case report. Toxicol Rep 2023;11:270-272. PubMed

See these in context on the Colloidal Silver monograph →

Oregano 12 references
  1. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  2. Benito M, Jorro G, Morales C, et al. Labiatae allergy: systemic reactions due to ingestion of oregano and thyme. Ann Allergy Asthma Immunol 1996;76:416-8. PubMed
  3. Chevallier A. Encyclopedia of Herbal Medicine. 2nd ed. New York, NY: DK Publ, Inc., 2000.
  4. Ciganda C, and Laborde A. Herbal infusions used for induced abortion. J Toxicol.Clin Toxicol. 2003;41:235-239. PubMed
  5. Futrell, J. M. and Rietschel, R. L. Spice allergy evaluated by results of patch tests. Cutis 1993;52(5):288-290.
  6. Tognolini, M., Barocelli, E., Ballabeni, V., Bruni, R., Bianchi, A., Chiavarini, M., and Impicciatore, M. Comparative screening of plant essential oils: phenylpropanoid moiety as basic core for antiplatelet activity. Life Sci. 2-23-2006;78(13):1419-1432. PubMed
  7. Goun, E., Cunningham, G., Solodnikov, S., Krasnykch, O., and Miles, H. Antithrombin activity of some constituents from Origanum vulgare. Fitoterapia 2002;73(7-8):692-694. PubMed
  8. Lemhadri, A., Zeggwagh, N. A., Maghrani, M., Jouad, H., and Eddouks, M. Anti-hyperglycaemic activity of the aqueous extract of Origanum vulgare growing wild in Tafilalet region. J Ethnopharmacol. 2004;92(2-3):251-256. PubMed
  9. McCue, P., Vattem, D., and Shetty, K. Inhibitory effect of clonal oregano extracts against porcine pancreatic amylase in vitro. Asia Pac.J Clin.Nutr. 2004;13(4):401-408.
  10. Ragi, J., Pappert, A., Rao, B., Havkin-Frenkel, D., and Milgraum, S. Oregano extract ointment for wound healing: a randomized, double-blind, petrolatum-controlled study evaluating efficacy. J.Drugs Dermatol. 2011;10(10):1168-1172.
  11. Singletary K. Oregano: overview of the literature on health benefits. Nutrition Today 2010;45(3):129-38.
  12. Silva MLAE, Lucarini R, Dos Santos FF, et al. Hypoglycemic effect of rosmarinic acid-rich infusion (RosCE) from Origanum vulgare in alloxan-induced diabetic rats. Nat Prod Res 2022;36(17):4525-4531.

See these in context on the Oregano monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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