Interactions on record — worth a quick check against your medications. Based on 3 of 4 ingredients. Check your meds →
Dietary supplement

Colloidal Silver Plus Herbal Topical Spray Ingredients & Drug Interactions

by Village Vitality

Liquid Category: Botanical With Nutrients
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Colloidal Silver Plus Herbal Topical Spray is a dietary supplement by Village Vitality with 4 active ingredients. Its ingredients are commonly taken for digestive upset, respiratory and cold symptoms, antimicrobial support.Based on those ingredients, 208 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Oregano Oil. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Colloidal Silver Plus Herbal Topical Spray by Village Vitality

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 4 active ingredients.

This spray contains 4 active ingredients. Oregano oil and tea tree oil are essential oils traditionally used on skin.

Olive provides antioxidant compounds, and colloidal silver is a suspension of tiny silver particles. The product also includes inactive ingredients — deionized water, grain alcohol, peppermint spirits, and soy lecithin — which serve as solvents and stabilizers.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: Topical skin protection and herbal care.
  • We looked for evidence on: Acne, Dandruff, Furuncles (boils), Insect bite, Lice, Onychomycosis — and 4 related terms.
  • The strongest evidence on file: Tea Tree Oil is rated "Possibly Effective" for Acne (Natural Medicines).
  • Also on file: Tea Tree Oil is rated "Possibly Effective" for Onychomycosis.
  • Also on file: Tea Tree Oil is rated "Insufficient Reliable Evidence To Rate" for Lice, Scabies, Insect bite, Rosacea, and more.

The evidence for what this spray actually does is thin. Oregano oil, olive, and colloidal silver all lack reliable evidence for the conditions they're commonly promoted for — acne, bronchitis, asthma, and upper respiratory infections among them.

Tea tree oil is the exception: it's possibly effective for acne, athlete's foot (tinea pedis), and fungal nail infections (onychomycosis), and we have at least some clinical backing for those uses. The rest of the ingredients fall short of solid proof.

The evidence, ingredient by ingredient Oregano Olive Tea Tree Oil

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Oregano oil is well tolerated in food amounts, but concentrated oregano supplements are less studied. Topically, it can cause irritation or allergic contact dermatitis in sensitive skin, and concentrated oregano over 1% can irritate mucous membranes.

Rare systemic allergic reactions have been reported. Tea tree oil is generally well tolerated when diluted on the skin but is toxic if swallowed — never ingest it.

Topically, it may cause burning, stinging, dryness, redness, or allergic reactions. Olive is very safe as food, but concentrated olive supplements are less studied.

The safety of colloidal silver as a supplement is not on file with us.

Side effects, ingredient by ingredient Oregano Olive Tea Tree Oil

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 3 matched ingredients can interact with medications — Oregano.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications.
  • For scale: 208 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before using this spray, double-check with your pharmacist if you take blood thinners (anticoagulants) or antiplatelet drugs — oregano oil may increase bleeding risk (Moderate severity). Also check if you take diabetes medications, as oregano could theoretically lower your blood sugar (Moderate severity).

No interactions are documented for the olive or tea tree oil ingredients we could check.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

If you have acne, athlete's foot, or fungal nails, the tea tree oil in this spray has some evidence behind it. If you take blood thinners or diabetes medication, check with your pharmacist before using this product — oregano oil may interfere.

For other uses, the evidence is lacking. Talk to your pharmacist if you have sensitive skin or a history of allergies to oregano or tea tree.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Colloidal Silver Plus Herbal Topical Spray, straight from the product label.

Brand Village Vitality
Barcode (UPC) 788332089619
Net contents 1 Fluid Ounce(s); 30 Milliliter(s)
Market status On market
Date entered into DSLD Sep 25, 2024
DSLD ID 310190
Product type Botanical With Nutrients
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Colloidal Silver Plus Herbal Topical Spray by Village Vitality, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
0 Not Present
Maximum serving Sizes:
0 Not Present
UPC/BARCODE
788332089619
IngredientAmount% DV
Oregano Oil0 NP--
Olive0 NP--
Silver, Colloidal0 NP--
Tea Tree Oil0 NP--

Other ingredients: Water, Deionized, Grain Alcohol, Peppermint Spirits, Soy Lecithin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested use Spray enough to cover affected area. Repeat as needed. Shake well before using as separation is normal.

Precautions

For topical use only Warnings: A slight warming sensation is normal.

Keep out of the reach of children.

Formulation

Bio protectant

FDA Statement of Identity

Herbal topical spray

FDA Disclaimer Statement

These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.

See for yourself

Colloidal Silver Plus Herbal Topical Spray by Village Vitality label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Colloidal Silver Plus Herbal Topical Spray by Village Vitality

These are the 4 active ingredients this product is made of. Select any to open its full monograph.

Serving size0 Not Present Dosage formLiquid Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Oregano Oil

Interacts with
208 drugs
0 NP per serving Form: Carvacrol

Oregano is a common Mediterranean cooking herb that is also sold as a concentrated oil or supplement, often standardized for a compound called carvacr...

Oregano Oil monograph & interactions

Olive

No known
interactions
0 NP per serving

Olive comes from the same tree that gives us olives and olive oil, and its leaf and fruit contain antioxidant compounds like oleuropein and hydroxytyr...

Olive monograph & interactions

Silver, Colloidal

0 NP per serving

Tea Tree Oil

No known
interactions
0 NP per serving

Tea tree oil is an essential oil used on the skin for acne, fungal infections, and other skin problems, with some supportive but limited evidence. It...

Tea Tree Oil monograph & interactions

Other (inactive) ingredients: Water, Deionized, Grain Alcohol, Peppermint Spirits, Soy Lecithin. These complete the product’s ingredient list but are not active constituents.

Interaction report

Colloidal Silver Plus Herbal Topical Spray by Village Vitality Drug Interactions

Want to check YOUR meds against Colloidal Silver Plus Herbal Topical Spray?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
208Drugs
208 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Colloidal Silver Plus Herbal Topical Spray with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Oregano Oil2 drug types · 208 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, oregano might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
In vitro research shows that aristolochic acid isolated from oregano leaves has antithrombin activity. It has also been reported that oregano oil inhibits arachidonic acid-induced, and ADP-induced, platelet aggregation.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, oregano might increase the risk for hypoglycemia when taken with antidiabetes drugs.
In vitro and animal research shows that oregano extracts might lower blood glucose levels.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Colloidal Silver Plus Herbal Topical Spray, from the product label.

Village Vitality

See all Village Vitality products
Name
Village Vitality LLC
Street Address
79 Tinker St, Floor 2
City
Woodstock
State
NY
ZipCode
12498
Pharmacist Counseling Corner

Colloidal Silver Plus Herbal Topical Spray by Village Vitality: Common Questions

Does Colloidal Silver Plus Herbal Topical Spray by Village Vitality interact with any medications?
Yes. Based on its ingredients, Colloidal Silver Plus Herbal Topical Spray has a known interaction with 208 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Colloidal Silver Plus Herbal Topical Spray contains 4 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I use this if I take warfarin or other blood thinners?
Not without checking with your pharmacist first. The oregano oil in this spray may increase your bleeding risk when combined with blood thinners — that's a real concern. Talk to your pharmacist about your specific medications before you start.
Will this spray help my acne?
Tea tree oil in the spray is possibly effective for acne, so there's some evidence to back that use. Oregano oil and olive lack reliable evidence for acne, though. Individual results vary, so give it time and talk to your skin doctor if you're not seeing improvement.
Is it safe to use this while pregnant?
The oregano oil should be avoided in medicinal or supplement amounts during pregnancy; food amounts are likely fine. Tea tree oil is rated as possibly safe in pregnancy but with limited data — we'd recommend checking with your doctor before using it. Safety data for olive and colloidal silver during pregnancy isn't on file with us either.
What if I accidentally swallow some of this spray?
Tea tree oil is toxic if swallowed — even small amounts like 2.5 mL can cause a rash and other problems. If someone swallows this spray, don't wait; contact poison control or seek medical attention right away.
Can I use this on sensitive skin?
Be careful. Both oregano oil and tea tree oil can cause irritation, burning, stinging, or allergic contact dermatitis, especially in people with sensitive skin. Do a patch test on a small area first, and stop if you see redness or itching.
Is this spray safe to use while breastfeeding?
There isn't enough data to know either way. Oregano oil and tea tree oil both have limited safety information for breastfeeding, and the same goes for olive and colloidal silver. Talk with your doctor or pharmacist before using it while nursing.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Colloidal Silver Plus Herbal Topical Spray is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Colloidal Silver Plus Herbal Topical Spray label
Sources

Sources & How We Checked

Colloidal Silver Plus Herbal Topical Spray's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 45 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Oregano 12 references
  1. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  2. Benito M, Jorro G, Morales C, et al. Labiatae allergy: systemic reactions due to ingestion of oregano and thyme. Ann Allergy Asthma Immunol 1996;76:416-8. PubMed
  3. Chevallier A. Encyclopedia of Herbal Medicine. 2nd ed. New York, NY: DK Publ, Inc., 2000.
  4. Ciganda C, and Laborde A. Herbal infusions used for induced abortion. J Toxicol.Clin Toxicol. 2003;41:235-239. PubMed
  5. Futrell, J. M. and Rietschel, R. L. Spice allergy evaluated by results of patch tests. Cutis 1993;52(5):288-290.
  6. Tognolini, M., Barocelli, E., Ballabeni, V., Bruni, R., Bianchi, A., Chiavarini, M., and Impicciatore, M. Comparative screening of plant essential oils: phenylpropanoid moiety as basic core for antiplatelet activity. Life Sci. 2-23-2006;78(13):1419-1432. PubMed
  7. Goun, E., Cunningham, G., Solodnikov, S., Krasnykch, O., and Miles, H. Antithrombin activity of some constituents from Origanum vulgare. Fitoterapia 2002;73(7-8):692-694. PubMed
  8. Lemhadri, A., Zeggwagh, N. A., Maghrani, M., Jouad, H., and Eddouks, M. Anti-hyperglycaemic activity of the aqueous extract of Origanum vulgare growing wild in Tafilalet region. J Ethnopharmacol. 2004;92(2-3):251-256. PubMed
  9. McCue, P., Vattem, D., and Shetty, K. Inhibitory effect of clonal oregano extracts against porcine pancreatic amylase in vitro. Asia Pac.J Clin.Nutr. 2004;13(4):401-408.
  10. Ragi, J., Pappert, A., Rao, B., Havkin-Frenkel, D., and Milgraum, S. Oregano extract ointment for wound healing: a randomized, double-blind, petrolatum-controlled study evaluating efficacy. J.Drugs Dermatol. 2011;10(10):1168-1172.
  11. Singletary K. Oregano: overview of the literature on health benefits. Nutrition Today 2010;45(3):129-38.
  12. Silva MLAE, Lucarini R, Dos Santos FF, et al. Hypoglycemic effect of rosmarinic acid-rich infusion (RosCE) from Origanum vulgare in alloxan-induced diabetic rats. Nat Prod Res 2022;36(17):4525-4531.

See these in context on the Oregano monograph →

Olive 2 references
  1. Liccardi G, D'Amato M, D'Amato G. Oleaceae pollinosis: a review. Int Arch Allergy Immunol 1996;111:210-7. PubMed
  2. Somerville V, Moore R, Braakhuis A. The effect of olive leaf extract on upper respiratory illness in high school athletes: A randomised control trial. Nutrients. 2019;11(2). pii: E358. PubMed

See these in context on the Olive monograph →

Tea Tree Oil 31 references
  1. Robbers JE, Tyler VE. Tyler's Herbs of Choice: The Therapeutic Use of Phytomedicinals. New York, NY: The Haworth Herbal Press, 1999.
  2. Foster S, Tyler VE. Tyler's Honest Herbal, 4th ed., Binghamton, NY: Haworth Herbal Press, 1999. DOI
  3. De Groot AC. Airborn allergic contact dermatitis from tea tree oil. Contact Dermatitis 1996;35:304-5.
  4. Rubel DM, Freeman S, Southwell IA. Tea tree oil allergy: what is the offending agent? Report of three cases of tea tree oil allergy and review of the literature. Australas J Dermatol 1998;39:244-7. PubMed
  5. Carson CF, Riley TV, Cookson BD. Efficacy and safety of tea tree oil as a topical antimicrobial agent. J Hosp Infect 1998;40:175-8. PubMed
  6. Bhushan M, Beck MH. Allergic contact dermatitis from tea tree oil in a wart paint. Contact Dermatitis 1997;36:117-8. PubMed
  7. Del Beccaro MA. Melaleuca oil poisoning in a 17-month-old. Vet Hum Toxicol 1995;37:557-8.
  8. Jandourek A, Vaishampayan JK, Vazquez JA. Efficacy of melaleuca oral solution for the treatment of fluconazole refractory oral candidiasis in AIDS patients. AIDS 1998;12:1033-7. DOI
  9. Zhang SY, Robertson D. A study of tea tree oil ototoxicity. Audiol Neurootol 2000;5:64-8. PubMed
  10. Bassett IB, Pannowitz DL, Barnetson RS. A comparative study of tea-tree oil versus benzoylperoxide in the treatment of acne. Med J Aust 1990;153:455-8. PubMed
  11. Jacobs MR, Hornfeldt CS. Melaleuca oil poisoning. J Toxicol Clin Toxicol 1994;32:461-4.. PubMed
  12. Elliott C. Tea tree oil poisoning. Med J Aust 1993;159:830-1. PubMed
  13. Knight TE, Hausen BM. Melaleuca oil (tea tree oil) dermatitis. J Am Acad Dermatol 1994;30:423-7.. PubMed
  14. Bruynzeel DP. Contact dermatitis due to tea tree oil. Trop Med Int Health 1999;4:630.
  15. Greig JE, Thoo SL, Carson CF, Riley TV. Allergic contact dermatitis following use of a tea tree oil hand-wash not due to tea tree oil. Contact Dermatitis 1999;41:354-5. PubMed
  16. Varma S, Blackford S, Statham BN, Blackwell A. Combined contact allergy to tea tree oil and lavender oil complicating chronic vulvovaginitis. Contact Dermatitis 2000;42:309-10.
  17. Khanna M, Qasem K, Sasseville D. Allergic contact dermatitis to tea tree oil with erythema multiforme-like id reaction. Am J Contact Dermat 2000;11:238-42..
  18. Satchell AC, Saurajen A, Bell C, Barnetson RS. Treatment of interdigital tinea pedis with 25% and 50% tea tree oil solution: a randomized, placebo-controlled, blinded study. Australas J Dermatol 2002;43:175-8.. PubMed
  19. Morris MC, Donoghue A, Markowitz JA, Osterhoudt KC. Ingestion of tea tree oil (Melaleuca oil) by a 4-year-old boy. Pediatr Emerg Care 2003;19:169-71. PubMed
  20. Martin KW, Ernst E. Herbal medicines for treatment of fungal infections: a systematic review of controlled clinical trials. Mycoses 2004;47:87-92. PubMed
  21. De Groot A. C. and Weyland J. W. Systemic contact dermatitis from tea tree oil. Contact Dermatitis 1992;27(4):279-280. PubMed
  22. Enshaieh S, Jooya A, Siadat AH, and Iraji F. The efficacy of 5% topical tea tree oil gel in mild to moderate acne vulgaris: a randomized, double-blind placebo-controlled study. Indian J Dermatol Venereol Leprol 2007;73(1):22-25. PubMed
  23. Christoffers WA, Blömeke B, Coenraads PJ, Schuttelaar ML. Co-sensitization to ascaridole and tea tree oil. Contact Dermatitis. 2013 Sep;69(3):187-9. PubMed
  24. Corazza M, Borghi A, Gallo R, Schena D, Pigatto P, Lauriola MM, Guarneri F, Stingeni L, Vincenzi C, Foti C, Virgili A. Topical botanically derived products: use, skin reactions, and usefulness of patch tests. A multicentre Italian study. Contact Dermatiti
  25. Kwon HH, Yoon JY, Park SY, Min S, Suh DH. Comparison of clinical and histological effects between lactobacillus-fermented Chamaecyparis obtusa and tea tree oil for the treatment of acne: an eight-week double-blind randomized controlled split-face study. D PubMed
  26. Martínez Campayo N, Goday Buján JJ, Fonseca Capdevila E. Allergic contact dermatitis due to tea tree oil. Actas Dermosifiliogr (Engl Ed). 2020;111(9):787-788. DOI
  27. Lauriola MM, Sena P, De Bitonto A, Corazza M. Allergic contact dermatitis due to "therapeutic uses" of tea tree oil on the lips and toenails. Dermatitis. 2021;32(3):e40-e41. PubMed
  28. Navarro-Triviño FJ, Prados-Carmona Á, Ruiz-Villaverde R. Systemic allergic contact dermatitis caused by tea tree oil in a cream for treatment of molluscum contagiosum. Contact Dermatitis 2022;87(3):285-287. PubMed
  29. Bekhof AMW, van Hunsel FPAM, van de Koppel S, Woerdenbag HJ. Safety assessment and adverse drug reaction reporting of tea tree oil (Melaleuca aetheroleum). Phytother Res 2022.
  30. Ambrogio F, Foti C, Cazzato G, et al. Spreading Allergic Contact Dermatitis to Tea Tree Oil in an Over-the-Counter Product Applied on a Wart. Medicina (Kaunas) 2022;58(5):561. PubMed
  31. Samaran Q, Litovsky J, Girod M, Dereure O, Raison-Peyron N. Allergic Contact Dermatitis to Tea Tree Oil With No Sensitization to Fragrance Markers. Dermatitis 2023. PubMed

See these in context on the Tea Tree Oil monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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