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Dietary supplement

Corn Silk 1,200 mg Ingredients & Drug Interactions

by Nature's Way

Corn Silk 1,200 mg label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Corn Silk 1,200 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Corn Silk 1,200 mg is a dietary supplement by Nature's Way with 1 active ingredient. Its ingredients are commonly taken for urinary tract and bladder problems, mild fluid retention (diuretic), kidney and prostate concerns.Based on those ingredients, 290 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Corn Silk. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Corn Silk 1,200 mg by Nature's Way

Ask about any prescription or over-the-counter medication and we check it for interactions with Corn Silk 1,200 mg by Nature's Way — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Corn Silk 1,200 mg by Nature's Way

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: corn silk (the stigma and styles from corn cobs), supplied at 1,200 mg per capsule. Corn silk has a long history in traditional medicine, particularly for urinary and cardiovascular concerns.

The capsule itself is made from hypromellose (a plant-based coating), with magnesium stearate added as a flow agent during manufacturing.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Corn Silk's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: Traditional support for urinary health.
  • We looked for evidence on: Nocturnal enuresis, Prostatitis, Urinary tract infections (UTIs), Urinary tract irritation, Bladder health, Kidney support — and 1 related terms.
  • The closest evidence on file: Corn Silk is rated "Insufficient Reliable Evidence To Rate" for Prostatitis (Natural Medicines).
  • Also on file: Corn Silk is rated "Insufficient Reliable Evidence To Rate" for Urinary tract infections (UTIs), Nocturnal enuresis.

The evidence we hold for corn silk does not establish that it works for any of its traditional uses — angina, heart disease, heart failure, depression, diabetes, or fatigue all carry a rating of insufficient reliable evidence. That means the research so far hasn't given us a clear answer either way.

If you're considering corn silk for any of these conditions, talk with your doctor about whether it makes sense for your situation.

The evidence, ingredient by ingredient Corn Silk

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Corn silk is generally well tolerated for short-term use, but human safety data are limited and a thorough safety evaluation has not been done. The most common concerns with oral use are low potassium (hypokalemia) and low sodium (hyponatremia), especially with prolonged use.

Adverse effects overall seem rare, though they haven't been exhaustively studied. During pregnancy, there isn't enough reliable safety data, so it's best avoided.

While breastfeeding, safety is unknown — only use it if a clinician approves. If applied to skin, corn silk can occasionally cause irritation (dermatitis) or hives (urticaria).

Side effects, ingredient by ingredient Corn Silk

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Corn Silk.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications.
  • For scale: 290 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you start, check your exact medications against these drug types: blood pressure medications (antihypertensive drugs), water pills (diuretics), diabetes drugs, corticosteroids, and warfarin. All carry Moderate interaction risks with corn silk.

Use the medication checker on this page to verify your prescriptions.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

Corn Silk by Nature's Way is generally well tolerated for short-term use, but it's not proven to work for any condition we have data on. If you take blood pressure pills, water pills, diabetes drugs, corticosteroids, or warfarin, this product isn't a simple add-on — you need to check with your pharmacist first.

Skip it in pregnancy, and get approval from your clinician before using it while breastfeeding.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Aug 22, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Corn Silk 1,200 mg, straight from the product label.

Brand Nature's Way
Barcode (UPC) 033674141526
Net contents 100 Vegan Capsule(s)
Market status On market
Date entered into DSLD Aug 22, 2025
DSLD ID 337246
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Corn Silk 1,200 mg by Nature's Way, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
3 Capsule(s)
Maximum serving Sizes:
3 Capsule(s)
Servings per container
33
UPC/BARCODE
033674141526
IngredientAmount% DV
Corn Silk1.2 Gram(s)--

Other ingredients: Hypromellose, Magnesium Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Traditional support for urinary health Botanicals are sourced where they grow best Made with the quality you trust Bottled and tested in the USA

Vegan V Gelatin free

Vegan V Gelatin free

Plant powered

Gluten free. No wheat, soy, dairy, gelatin, or artificial colors or flavors.

Formula

Corn Silk With 1,200 mg corn silk per 3-capsule serving

Corn Silk 1,200 mg per 3-capsule serving

General Statements

Explore more products at naturesway.com Bottles made from 50% post-consumer recycled plastic

Brand IP Statement(s)

Copyright 2025 Nature's Way Brands, LLC

Seals/Symbols

Vegan V Gelatin free

FDA Disclaimer Statement

These statements have not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Recommendation: Adults take 3 capsules daily with food or water.

Precautions

If you are pregnant, nursing, or taking any medications, consult a healthcare professional before use.

Keep out of reach of children.

Safety sealed with inner seal. Do not use if seal is broken or missing.

Storage

Keep tightly closed. Store at room temperature. Avoid excessive heat and direct sunlight.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Corn Silk 1,200 mg by Nature's Way label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Corn Silk 1,200 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Corn Silk 1,200 mg by Nature's Way

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size3 Capsule(s) Dosage formCapsule Servings per container33 Amounts shown are per serving.

Corn Silk

Interacts with
290 drugs
1.2 Gram(s) per serving

Corn silk is a traditional herbal remedy taken as a tea or extract, mostly for urinary and mild fluid-related complaints. High-quality human evidence...

Corn Silk monograph & interactions

Other (inactive) ingredients: Hypromellose, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Corn Silk 1,200 mg by Nature's Way Drug Interactions

Want to check YOUR meds against Corn Silk 1,200 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
290Drugs
290 Moderate

Ingredients driving the most interactions

Corn Silk 290

Individual Drug Interactions

The ingredients in Corn Silk 1,200 mg interact with 290 drugs. Click any drug to see the details.

1 of the 1 ingredient in Corn Silk 1,200 mg interact with drugs. Each result below shows which ingredient is responsible. Corn Silk

Each ingredient & the kinds of drugs it affects

For each ingredient in Corn Silk 1,200 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Corn Silk5 drug types · 290 drugs

Antidiabetes Drugs

Theoretically, taking corn silk with antidiabetes drugs might increase the risk of hypoglycemia.
Animal research in diabetic mice shows that taking corn silk extract lowers fasting blood glucose levels.

Likelihood Possible Evidence D
Antihypertensive Drugs

Taking corn silk extract with antihypertensive drugs might increase the risk of hypotension.
Clinical research in both hypertensive and normotensive adults shows that taking corn silk extract lowers systolic and diastolic blood pressure.

Likelihood Possible Evidence D
Corticosteroids

Taking corn silk with corticosteroids might increase the risk of hypokalemia.
Clinical research shows that taking corn silk extract increases the urinary excretion of potassium.

Likelihood Possible Evidence D
Diuretic Drugs

Taking corn silk with diuretic drugs might increase the risk of adverse effects such as hyponatremia and hypokalemia.
Clinical research shows that taking corn silk extract increases urine volume and promotes the urinary excretion of sodium and potassium. Some patients may require electrolyte supplementation.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Theoretically, suddenly stopping, starting, or changing corn silk treatment may alter the effects of warfarin.
Corn silk contains vitamin K. Individuals taking warfarin should consume a consistent daily amount of corn silk to maintain consistent anticoagulation.

Likelihood Likely Evidence D
Corn Silk full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Corn Silk 1,200 mg, from the product label.

Nature's Way

See all Nature's Way products
Name
Nature's Way Brands, LLC
City
Green Bay
State
WI
ZipCode
54311
Phone Number
1-800-962-8873
Web Address
naturesway.com
Pharmacist Counseling Corner

Corn Silk 1,200 mg by Nature's Way: Common Questions

Does Corn Silk 1,200 mg by Nature's Way interact with any medications?
Yes. Based on its ingredients, Corn Silk 1,200 mg has a known interaction with 290 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Corn Silk 1,200 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take corn silk if I'm on a blood pressure medication?
Not without checking first. Corn silk lowers blood pressure on its own, so combining it with blood pressure drugs could drop your pressure too low. Talk to your pharmacist — they can look at your specific medication and dose to figure out if it's safe for you.
Does corn silk really help with diabetes or heart disease?
The evidence we have isn't strong enough to say. Animal studies suggest corn silk might lower blood sugar, but we don't have reliable human evidence yet for diabetes — or for heart disease, angina, heart failure, depression, or fatigue. Don't rely on it as a treatment without your doctor's input.
What are the most common side effects?
Low potassium and low sodium are the main concerns, especially with long-term use. Adverse effects seem to be rare overall, but the full safety picture hasn't been thoroughly studied. If you feel weak, have muscle cramps, or feel dizzy, mention it to your pharmacist or doctor.
Is corn silk safe during pregnancy?
No — there isn't enough reliable safety data, so it's best avoided when you're pregnant. Talk with your doctor about what's safe for you during pregnancy.
Can I use it while breastfeeding?
Safety while breastfeeding is unknown. Only use it if a clinician approves and is monitoring you. Check with your doctor or pharmacist first.
I take warfarin — can I use this?
Corn silk contains vitamin K, which warfarin is sensitive to. You can use it, but only if you keep the amount you take consistent every day — sudden changes could throw off how well your blood thinner works. Talk to your pharmacist about the right approach for you.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Corn Silk 1,200 mg is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Corn Silk 1,200 mg label
Go deeper

The Full Monographs Behind Corn Silk 1,200 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Corn Silk

Interacts with 290 drugs

Corn silk is a traditional herbal remedy taken as a tea or extract, mostly for urinary and mild fluid-related complaints. High-quality human evidence for these uses is limited, so it should...

Read the full Corn Silk monograph →
Sources

Sources & How We Checked

Corn Silk 1,200 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Corn Silk 4 references
  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  2. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  3. George GO, Idu FK. Corn silk aqueous extracts and intraocular pressure of systemic and non-systemic hypertensive subjects. Clin Exp Optom. 2015 Mar;98(2):138-49. PubMed
  4. Sheng L, Chen Q, Di L, Li N. Evaluation of anti-diabetic potential of corn silk in high-fat diet/streptozotocin- induced type 2 diabetes mice model. Endocr Metab Immune Disord Drug Targets. 2020. PubMed

See these in context on the Corn Silk monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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