Interactions on record — worth a quick check against your medications. Based on 1 of 2 ingredients. Check your meds →
Dietary supplement

CortSTAT Ingredients & Drug Interactions

by SAN

CortSTAT label
See full label image
Capsule Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking CortSTAT against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

CortSTAT is a dietary supplement by SAN with 2 active ingredients. Its ingredients are commonly taken for memory and cognitive support, age-related cognitive decline, attention and focus (adhd).Based on those ingredients, 219 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Phosphatidylserine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against CortSTAT by SAN

Ask about any prescription or over-the-counter medication and we check it for interactions with CortSTAT by SAN — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of CortSTAT by SAN

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 16, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

CortSTAT contains 2 active ingredients. Phosphatidylserine is a phospholipid — a fatty compound found naturally in cell membranes — that's been studied for brain health and cognitive support.

Alanyl-L-glutamine dipeptide is a combination of two amino acids (the building blocks of protein); we don't have detailed information on file about what role it plays in this formulation. The capsule itself contains several inactive ingredients: calcium carbonate, hydroxypropyl methyl cellulose, microcrystalline cellulose, silica, and magnesium stearate — these are standard binders and fillers that help hold the capsule together and aid absorption.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Phosphatidylserine's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: muscle tissue maintenance post-workout.
  • We looked for evidence on: Athletic performance, Exercise-induced muscle soreness, Muscle protein synthesis, Exercise recovery, Cortisol management, Muscle breakdown prevention.
  • The closest evidence on file: Phosphatidylserine is rated "Insufficient Reliable Evidence To Rate" for Athletic performance (Natural Medicines).
  • Also on file: Phosphatidylserine is rated "Insufficient Reliable Evidence To Rate" for Exercise-induced muscle soreness.

Phosphatidylserine is rated possibly effective for age-related cognitive decline and Alzheimer disease based on the evidence we hold. For other uses in this product — athletic performance, ADHD, general cognitive function, and dementia — the evidence is insufficient to rate whether it works.

We don't have effectiveness data on file for alanyl-L-glutamine dipeptide.

The evidence, ingredient by ingredient Phosphatidylserine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Phosphatidylserine is generally well tolerated in studies, though long-term safety hasn't been fully established. The most common side effects are flatulence, stomach upset, headache, insomnia, and nausea — insomnia is more likely at higher doses (600 mg or more), and stomach upset can occur at doses of 200–300 mg per day.

There isn't enough safety data to use phosphatidylserine during pregnancy, so it's best to avoid it if you're pregnant. Safety while breastfeeding is also unknown, so avoidance is recommended.

Talk with your doctor or pharmacist about whether this product is right for you if you're pregnant, planning to become pregnant, or breastfeeding.

Side effects, ingredient by ingredient Phosphatidylserine

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Phosphatidylserine.
  • The most serious interaction on file is rated Moderate.
  • For scale: 219 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take CortSTAT, double-check with your pharmacist or doctor if you're on anticholinergic drugs (such as oxybutynin, benztropine, or scopolamine) or cholinergic drugs (such as donepezil, physostigmine, or pilocarpine) — phosphatidylserine may theoretically reduce their effectiveness or cause additive effects. We couldn't check the other ingredient in this product for interactions, so a full medication review with your own healthcare provider is important.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

CortSTAT may be worth considering if you're interested in supporting cognitive health, particularly for age-related decline or Alzheimer disease. However, if you take anticholinergic or cholinergic medications, check with your doctor or pharmacist before starting — this product may interfere with how they work.

It's generally well tolerated, but watch for stomach upset or sleep problems. Talk it over with your own healthcare provider to make sure it fits your situation.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Apr 25, 2018.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about CortSTAT, straight from the product label.

Brand SAN
Barcode (UPC) 672898520030
Net contents 60 Capsule(s)
Market status On market
Date entered into DSLD Apr 25, 2018
DSLD ID 175284
Product type Other Combinations
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for CortSTAT by SAN, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
30
UPC/BARCODE
672898520030
IngredientAmount% DV
Alanyl-L-Glutamine Dipeptide800 mg--
Phosphatidylserine200 mg--

Other ingredients: Calcium Carbonate, Hydroxypropyl Methyl Cellulose, Microcrystalline Cellulose, Silica, Magnesium Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Recommended Use: Take 2 capsules on workout days. During intense dieting, take 1 capsule on non-workout days before bedtime. Consume CortSTAT with at least 6-8 ounces of water.

As a dietary supplement, use CortSTAT as a key substrate to thwart exercise induced stress muscle tissue cannibalization.

Storage

Storage Instructions: Protect from heat and freezing. Keep away from local space heat sources such as space heaters and radiators. Do not expose to direct sunlight or leave in vehicle exposed to sunlight. Do not allow exposure to high humidity (above 65%). Keep container tightly closed when not in use.

Precautions

Keep away from local space heat sources such as space heaters and radiators. Do not expose to direct sunlight or leave in vehicle exposed to sunlight. Do not allow exposure to high humidity (above 65%).

Manufactured in a facility that also processes egg, shellfish, fish, soy, peanuts, tree nuts and milk ingredients.

General Statements

Description: Elevated cortisol levels in the athlete are known to break down muscle tissue via inhibiting muscle protein synthesis. CortSTAT by San is a bona fide new formula that supports the maintenance of muscle tissue post-workout. Very recent research has shown that lowered levels of cortisol enable greater amino acid utilization for enhanced nitrogen retention, glycogen synthesis and protein synthesis.

SAN products are manufactured under GMP (Good Manufacturing Practices) standards with stringent quality control guidelines. Additionally, each lot produced by SAN is independently tested for purity and potency by HPLC analysis to ensure only the highest quality ingredients in our innovative formulas.

Live a vibrant life! Veggie caps Post-workout modulator

30 full dosage servings

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Formula

800 mg GlutaDiPEP Alanyl-L-Glutamine Dipeptide 200 mg SerinAid Phospatidylserine

Seals/Symbols

GMP Certified GMP Manufactured GMP Certified Facility

FDA Manufacture in an FDA Registered facility

HPLC & FTIR Tested Quality Approved

Made in the U.S.A.

FDA Statement of Identity

Dietary Supplement

General

Ver 1

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

CortSTAT by SAN label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

CortSTAT label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in CortSTAT by SAN

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Alanyl-L-Glutamine Dipeptide

800 mg per serving

Phosphatidylserine

Interacts with
219 drugs
200 mg per serving

Phosphatidylserine is a natural fat-like compound found in cell membranes, especially in the brain, and it is sold mainly to support memory and thinki...

Phosphatidylserine monograph & interactions

Other (inactive) ingredients: Calcium Carbonate, Hydroxypropyl Methyl Cellulose, Microcrystalline Cellulose, Silica, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

CortSTAT by SAN Drug Interactions

Want to check YOUR meds against CortSTAT?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
219Drugs
219 Moderate

Ingredients driving the most interactions

Phosphatidylserine 219

Individual Drug Interactions

The ingredients in CortSTAT interact with 219 drugs. Click any drug to see the details.

1 of the 2 ingredients in CortSTAT interact with drugs. Each result below shows which ingredient is responsible. Phosphatidylserine

Each ingredient & the kinds of drugs it affects

For each ingredient in CortSTAT with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Phosphatidylserine2 drug types · 219 drugs

Anticholinergic Drugs

Theoretically, phosphatidylserine might decrease the effectiveness anticholinergic drugs.
Phosphatidylserine is thought to increase acetylcholine levels, which could theoretically interfere with the activity of anticholinergic agents.

Likelihood Possible Evidence B
Cholinergic Drugs

Theoretically, phosphatidylserine might have additive effects with cholinergic drugs.
Phosphatidylserine is thought to increase acetylcholine levels, which could theoretically lead to additive cholinergic effects when used with cholinergic drugs.

Likelihood Possible Evidence B
Phosphatidylserine full monograph & interactions
The maker

Brand information

Manufacturer and brand details for CortSTAT, from the product label.

SAN

See all SAN products
Name
SAN Corporation
Street Address
716 N. Ventura Road #431
City
Oxnard
State
CA
ZipCode
93030
Phone Number
(888) 519-9300
Web Address
Vibrantlife.net
Pharmacist Counseling Corner

CortSTAT by SAN: Common Questions

Does CortSTAT by SAN interact with any medications?
Yes. Based on its ingredients, CortSTAT has a known interaction with 219 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
CortSTAT contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is phosphatidylserine, and what's it supposed to do?
Phosphatidylserine is a fatty compound that naturally occurs in cell membranes. It's been studied for supporting brain health and cognitive function, particularly for age-related memory decline and Alzheimer disease — that's where the evidence is strongest.
Can I take this if I'm pregnant or breastfeeding?
No — there isn't enough safety information for pregnancy, so it's best to avoid it. Safety while breastfeeding is also unknown, so avoidance is recommended. Talk with your doctor about what's right for you.
What side effects should I watch for?
The most common are stomach upset (including gas and nausea), headache, and insomnia. Insomnia is more likely if the dose is high (600 mg or more), and stomach upset can happen at lower doses (200–300 mg per day). Stop and check with your pharmacist if side effects bother you.
Does CortSTAT actually work for memory and thinking?
Phosphatidylserine is rated possibly effective for age-related cognitive decline and Alzheimer disease. For other uses — like ADHD, athletic performance, or general brain function — the evidence isn't strong enough to say whether it works. We don't have effectiveness data on the other ingredient.
How do I know if this interacts with my medications?
Use the search tool on this page to check your specific drugs. The main concern is with anticholinergic and cholinergic medications — this product may reduce how well they work or boost their effects. Your pharmacist or doctor can review your full list.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

CortSTAT label
Go deeper

The Full Monographs Behind CortSTAT’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Phosphatidylserine

Interacts with 219 drugs

Phosphatidylserine is a natural fat-like compound found in cell membranes, especially in the brain, and it is sold mainly to support memory and thinking. Some research suggests possible bene...

Read the full Phosphatidylserine monograph →
Sources

Sources & How We Checked

CortSTAT's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 9 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Phosphatidylserine 9 references
  1. Crook T, Petrie W, Wells C, Massari DC. Effects of phosphatidylserine in Alzheimer's disease. Psychopharmacol Bull 1992;28:61-6.
  2. Pepping J. Phosphatidylserine. Am J Health-Syst Pharm 1999;56:2038,2043-4.
  3. Kidd PM. Phosphatidylserine; Membrane nutrient for memory. A clinical and mechanistic assessment. Altern Med Rev 1996;1:70-84.
  4. Kim HY, Akbar M, Lau A, et al. Inhibition of neuronal apoptosis by docosahexaenoic acid (22:6n-3). Role of phosphatidylserine in antiapoptotic effect. J Biol Chem 2000;275:35215-23.. PubMed
  5. Zanotti A, Valzelli L, Toffano G. Chronic phosphatidylserine treatment improves spatial memory and passive avoidance in aged rats. Psychopharmacology (Berl) 1989;99:316-21.. PubMed
  6. Schreiber S, Kampf-Sherf O, Gorfine M, et al. An open trial of plant-source derived phosphatydilserine for treatment of age-related cognitive decline. Isr J Psychiatry Relat Sci 2000;37:302-7.
  7. Pepping, J. Phosphatidylserine. Am J Health Syst.Pharm. 10-15-1999;56(20):2038, 2043-2038, 2044.
  8. Monteverde, A., Gnemmi, P., Rossi, F., Monteverde, A., and Finali, G. C. Selegiline in the treatment of mild to moderate Alzheimer-type dementia. Clin.Ther 1990;12(4):315-322.
  9. Vakhapova V, Cohen T, Richter Y, Herzog Y, Kam Y, Korczyn AD. Phosphatidylserine containing omega-3 Fatty acids may improve memory abilities in nondemented elderly individuals with memory complaints: results from an open-label extension study. Dement Geri PubMed

See these in context on the Phosphatidylserine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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