Cramp Bark Ingredients & Drug Interactions
by Herb Pharm
What is this page for?
First and foremost: checking Cramp Bark against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Cramp Bark is a dietary supplement by Herb Pharm with 1 active ingredient. Its ingredients are commonly taken for menstrual cramps, muscle spasms, general cramping pain.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.
HelloPharmacist Scorecard of Cramp Bark by Herb Pharm
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: Cramp Bark Bark Extract, a liquid extract made from the bark of the cramp bark plant. The extract is prepared using cane alcohol, distilled water, and glycerin as inactive ingredients (solvents and preservatives that help deliver the active component).
Does it work?
Insufficient evidence
The evidence for Cramp Bark isn't established in the data we hold. The product is traditionally used for muscle cramps, dysmenorrhea (period pain), pregnancy-related leg cramps, kidney stones, and diabetes, but we don't have reliable research to rate how well it works for any of those uses.
If you're considering it for a specific condition, talk with your pharmacist or doctor about what the science actually supports.
How safe is it?
Some data gaps
Cramp Bark is generally used in traditional medicine, but human safety data are limited — we simply don't know a lot about how it behaves in people long-term. The safety data advises against it during pregnancy and breastfeeding, so if you're pregnant, nursing, or planning to be, skip this one and talk with your doctor about other options.
Meds to double-check
No known interactions
No interactions are documented for Cramp Bark in our data. Still, run your exact medications through the search tool on this page or ask us before you start, just to be thorough.
The bottom line
Scorecard at a glanceFully disclosed formula with insufficient evidence for its stated purpose. No medication interactions are currently documented, and some safety-information gaps remain.
Cramp Bark has a long history in herbal medicine, but the evidence for how well it works isn't solid. It's not recommended during pregnancy or breastfeeding.
If you're considering it, chat with your pharmacist first — especially if you have a specific health concern or take other medications regularly.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jul 24, 2025.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Cramp Bark, straight from the product label.
| Brand | Herb Pharm |
|---|---|
| Barcode (UPC) | 090700001414 |
| Net contents | 4 Fluid Ounce(s); 120 mL |
| Market status | On market |
| Date entered into DSLD | Jul 24, 2025 |
| DSLD ID | 334516 |
| Product type | Botanical |
| Supplement form | Liquid |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Cramp Bark by Herb Pharm, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Cramp Bark Bark Extract | 657 mg | -- |
Other ingredients: Cane Alcohol, Water, Distilled, Glycerin
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Suggested use Shake well before using Adults: Add 1 squeeze of the dropper bulb to 2 oz. of water or juice, 2 to 5 times per day. Best taken between meals.
Precautions
Keep out of the reach of children
Storage
Store away from heat & light
Formula
Viburnum opulus
Cramp bark liquid extract
Formulation
System restoration Musculoskeletal
Gluten-free
We prepare our Cramp Bark Extract from the bark of Viburnum opulus trees which are responsibly wildcrafted in their natural habitat.
FDA Statement of Identity
Herbal Supplement
FDA Disclaimer Statement
This statement has not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Cramp Bark by Herb Pharm label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Cramp Bark by Herb Pharm
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size0.7 mL Dosage formLiquid Servings per container168 Amounts shown are per serving.
Cramp Bark Bark Extract
No knowninteractions
Cramp Bark is the dried bark of Viburnum opulus, traditionally used to ease muscle and menstrual cramps. Modern, high-quality human studies are very l...
Cramp Bark Bark Extract monograph & interactionsOther (inactive) ingredients: Cane Alcohol, Water, Distilled, Glycerin. These complete the product’s ingredient list but are not active constituents.
Cramp Bark by Herb Pharm Drug Interactions
We don’t currently list any known drug interactions for the mapped ingredients in Cramp Bark. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.
Brand information
Manufacturer and brand details for Cramp Bark, from the product label.
Herb Pharm
See all Herb Pharm products- Name
- Herb Pharm
- City
- Williams
- State
- OR
- ZipCode
- 97544
- Phone Number
- 800-348-4372
- Web Address
- www.herb-pharm.com
Cramp Bark by Herb Pharm: Common Questions
Does Cramp Bark by Herb Pharm interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Is Cramp Bark safe to take while I'm pregnant?
Can I take Cramp Bark while breastfeeding?
Does Cramp Bark actually work for muscle cramps?
What are the side effects?
Is this product a single ingredient or a blend?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Cramp Bark is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Cramp Bark’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Cramp Bark's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC