Major interaction on record — check this product against your medications before combining. Based on 5 of 12 ingredients. Check your meds →
Dietary supplement

Creamean Watermelon Rush Ingredients & Drug Interactions

by Chaotic-Labz

Creamean Watermelon Rush label
See full label image
Powder Category: Other Combinations
Most serious interaction: Major
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Creamean Watermelon Rush against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

Creamean Watermelon Rush is a dietary supplement by Chaotic-Labz with 12 active ingredients. Its ingredients are commonly taken for athletic performance and endurance, high-intensity exercise capacity, reducing muscle fatigue.Based on those ingredients, 229 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are L-Taurine, Adenosine 5'-Triphosphate, Inosine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Creamean Watermelon Rush by Chaotic-Labz

Ask about any prescription or over-the-counter medication and we check it for interactions with Creamean Watermelon Rush by Chaotic-Labz — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Creamean Watermelon Rush by Chaotic-Labz

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 16, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 12 active ingredients.
  • “Proprietary Blend” is a proprietary blend — the label gives one combined amount (9,994 mg) without saying how much of each component you get.

Creamean Watermelon Rush contains 12 ingredients, most of them variations on creatine (Creatine Ethyl Ester HCl, Creatine Monohydrate, Creatine Glycerol Phosphate, Disodium Creatine Phosphate, and Creatine α-Ketoglutarate). You're also getting Beta-Alanine for muscular endurance, L-Taurine for cardiovascular support, Inosine, and Adenosine 5'-Triphosphate.

The inactive ingredients include citric acid, acesulfame-K, sucralose, natural and artificial flavors, and silica.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: muscle strength and athletic exercise performance.
  • We looked for evidence on: Athletic performance, Exercise-induced muscle breakdown, Exercise-induced muscle soreness, Muscle strength, Physical performance, muscular endurance — and 2 related terms.
  • The strongest evidence on file: Creatine is rated "Possibly Effective" for Athletic performance (Natural Medicines).
  • Also on file: Creatine is rated "Possibly Effective" for Muscle strength.
  • Also on file: Beta-alanine is rated "Possibly Effective" for Athletic performance, Physical performance.

The creatine forms in this product are rated Possibly Effective for muscle strength and athletic performance, and Possibly Effective for sarcopenia (age-related muscle loss). Beta-Alanine is Possibly Effective for athletic and physical performance.

The evidence for L-Taurine shows it's Possibly Effective for congestive heart failure and hepatitis, though it's rated Possibly Ineffective for weight loss. Inosine and Adenosine 5'-Triphosphate lack reliable evidence for most conditions listed — the data we hold doesn't establish whether they work for the uses often claimed.

The evidence, ingredient by ingredient Beta-alanine Taurine Inosine Creatine Adenosine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 5 of the 5 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 5 of 5.
  • General safety write-ups exist for 5 of 5.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Creatine is generally well tolerated in healthy adults, but common side effects include dehydration, diarrhea, muscle cramps, and water retention. Those with kidney problems should be cautious.

Beta-Alanine commonly causes a harmless tingling sensation in the skin, starting on the scalp within 20 minutes and lasting about an hour — this is dose-dependent and mild at lower amounts. L-Taurine can cause constipation, diarrhea, or indigestion, and in rare cases hypersensitivity reactions in people sensitive to sulfites or sulfur-containing compounds.

Inosine raises uric acid levels and may cause kidney stones, especially at doses of 1–2 grams daily, and is riskier in people with gout or kidney disease. None of these ingredients should be used during pregnancy or breastfeeding — the safety data either advises against use or is too limited to know either way.

Side effects, ingredient by ingredient Beta-alanine Taurine Inosine Creatine Adenosine

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 3 of the 5 matched ingredients can interact with medications — Inosine, Taurine, Adenosine.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: lithium.
  • For scale: 229 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your doctor or pharmacist before starting this product if you take dipyridamole (Persantine) — it carries a Major interaction risk with the adenosine in this formula. Also double-check if you're on blood pressure medication, lithium, gout medication, carbamazepine (Tegretol), or regular caffeine supplements (Moderate to Minor interactions).

If you don't take any of these, use the search tool on this page to verify your exact medications.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Major medication interactions have been identified, and safety information is well characterized.

This is designed for athletes looking to boost muscle performance and endurance. If you take blood pressure medication, lithium, gout medication, dipyridamole, carbamazepine, or caffeine-containing products, check with your doctor or pharmacist before starting — several ingredients interact with these drugs.

People with kidney disease or gout should talk it over with their provider before using it. Generally it's well tolerated, but tingling and water retention are common.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 9 of 12 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jan 23, 2015.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Creamean Watermelon Rush, straight from the product label.

Brand Chaotic-Labz
Barcode (UPC) 283333505408
Net contents 308 Gram(s)
Market status On market
Date entered into DSLD Jan 23, 2015
DSLD ID 41143
Product type Other Combinations
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Creamean Watermelon Rush by Chaotic-Labz, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
11 Gram(s)
Maximum serving Sizes:
11 Gram(s)
Servings per container
28
UPC/BARCODE
283333505408
IngredientAmount% DV
Beta-Alanine0 NP--
L-Taurine0 NP--
Inosine0 NP--
Creatine Ethyl Ester HCl0 NP--
Proprietary Blend9994 mg--
Creatine Monohydrate0 NP--
Creatine Glycerol Phosphate0 NP--
Creatine-O-Phosphate0 NP--
Di Creatine Malate0 NP--
Disodium Creatine Phosphate0 NP--
Creatine {Alpha}-Ketoglutarate0 NP--
Guanido-Propionic Acid0 NP--
Adenosine 5'-Triphosphate0 NP--

Other ingredients: Citric Acid, Acesulfame-K, Sucralose, Natural and Artificial flavors, Silica

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

SUGGESTED USE: FOR THIS VICIOUS CREATINE BLEND TRAINING DAYS: As a dietary supplement consume 1 heaping scoop with 18 ounces of water 30 minutes prior to working out. Continue consuming generous amounts of water throughout your workout. FOR XTREME RESULTS: Take another heaping Scoop with 18 ounces of water immediately after your training session. NON-TRAINING DAYS: As a dietary supplement consume 1 scoop with 18 ounces of water first thing in the morning.

Precautions

ATTENTION: CREAMEAN(TM) USERS ARE REQUIRED TO CONSUME A MINIMUM OF 128 OUNCES OF WATER PER DAY WHILE USING THIS PRODUCT. YES THAT MEANS DRINK A WHOLE M'F'n GALLON OF WATER EVERY DAY!!

WARNING *WARNING *WARNING *WARNING *WARNING Do not use if you are pregnant or lactating.

Please consult your physician before starting any exercise or nutritional program.

KEEP OUT OF REACH OF CHILDREN.

Brand IP Statement(s)

CREAMEAN(TM) THE MOST BAD ASS CREATINE ON THE PLANET !

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to prevent, treat, diagnose, or cure any disease.

General Statements

SCAN ME {QRC}

BUY IT - TAKE IT- LOVE IT

MADE IN THE U.S.A.

KILL THE COMPETITION

THE FUTURE OF CREATINE IS NOW

- INCREASES STRENGTH - INCREASES RECOVERY - INCREASES EXPLOSIVENESS - XTREME ABSORPTION & BIO-AVAILABILITY - NO STOMACH DISCOMFORT - EXCEPTIONAL FLAVORING SYSTEM - INCREASES RAW POWER - INCREASES ENDURANCE - INCREASES MUSCULAR ENERGY - TOTALLY WATER SOLUBLE - NO FAT STORAGE OR BLOATING - ATP IN DA HOUSE (COME GET SOME)

Storage

Keep this bottle tightly closed in a cool, dry place, away from moisture.

FDA Statement of Identity

DIETARY SUPPLEMENT

Seals/Symbols

{Pinterest}

{Instagram}

{YouTube}

{twitter}

{facebook}

KILL THE COMPETITION CHAOTIC LABZ XTREME SPORTS NUTRITION

CHAOTIC LABS

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Creamean Watermelon Rush by Chaotic-Labz label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Creamean Watermelon Rush label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Creamean Watermelon Rush by Chaotic-Labz

These are the 12 active ingredients this product is made of. Select any to open its full monograph.

Serving size11 Gram(s) Dosage formPowder Servings per container28 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Proprietary Blend

9994 mg per serving

Other (inactive) ingredients: Citric Acid, Acesulfame-K, Sucralose, Natural and Artificial flavors, Silica. These complete the product’s ingredient list but are not active constituents.

Interaction report

Creamean Watermelon Rush by Chaotic-Labz Drug Interactions

Want to check YOUR meds against Creamean Watermelon Rush?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
229Drugs
2 Major 183 Moderate 44 Minor

Ingredients driving the most interactions

L-Taurine 173
Adenosine 5'-Triphosphate 47
Inosine 9

Individual Drug Interactions

The ingredients in Creamean Watermelon Rush interact with 229 drugs. Click any drug to see the details.

3 of the 12 ingredients in Creamean Watermelon Rush interact with drugs. Each result below shows which ingredient is responsible. L-Taurine Adenosine 5'-Triphosphate Inosine

Each ingredient & the kinds of drugs it affects

For each ingredient in Creamean Watermelon Rush with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

L-Taurine2 drug types · 173 drugs

Antihypertensive Drugs

Theoretically, taurine might increase the risk of hypotension when taken with antihypertensive drugs.
Some clinical evidence suggests that taurine can reduce both systolic and diastolic blood pressure.

Likelihood Probable Evidence D
Lithium

Theoretically, taurine might reduce excretion and increase plasma levels of lithium.
Taurine is thought to have diuretic properties, which might reduce the excretion of lithium.

Likelihood Probable Evidence D
L-Taurine full monograph & interactions

Adenosine 5'-Triphosphate3 drug types · 47 drugs

Dipyridamole (Persantine)

Dipyridamole can increase the therapeutic and toxic effects of adenosine.
Dipyridamole decreases the metabolism of adenosine. Intravenous infusion of adenosine in patients who are taking dipyridamole can cause dizziness, bradycardia, and syncope. Dipyridamole should be discontinued for several days prior to a cardiac stress test using adenosine.

Likelihood Likely Evidence D
Carbamazepine (Tegretol)

Carbamazepine might increase the risk of heart block when used concomitantly with adenosine.
Carbamazepine and adenosine can both cause heart block. Giving them concurrently might produce an additive effect.

Likelihood Possible Evidence D
Methylxanthines

Methylxanthines are competitive antagonists of adenosine and can block its pharmacologic effects.
The methylxanthines, aminophylline, caffeine, and theophylline, can block the effects of adenosine by acting as competitive antagonists at adenosine cell surface receptors. It is recommended that methylxanthines be avoided for 24 hours prior to cardiac stress tests.

Likelihood Possible Evidence D
Adenosine 5'-Triphosphate full monograph & interactions

Inosine1 drug type · 9 drugs

Antigout Drugs

Inosine might reduce the effects of antigout medications.
Inosine increases uric acid levels in the serum and urine, potentially resulting in hyperuricemia and reducing the effects of medications used for the prevention and treatment of gout.

Likelihood Possible Evidence D
Inosine full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Creamean Watermelon Rush, from the product label.

Chaotic-Labz

See all Chaotic-Labz products
Web Address
www.chaoticlabz.com
Pharmacist Counseling Corner

Creamean Watermelon Rush by Chaotic-Labz: Common Questions

Does Creamean Watermelon Rush by Chaotic-Labz interact with any medications?
Yes. Based on its ingredients, Creamean Watermelon Rush has a known interaction with 229 medications, including 2 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Creamean Watermelon Rush contains 12 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this make my skin tingle?
Yes, likely — Beta-Alanine commonly causes a harmless pins-and-needles feeling, usually on the scalp, starting within 20 minutes of taking it and lasting roughly an hour. It's dose-dependent, so lower amounts cause milder tingling; at the smallest doses, fewer than one in four people experience it.
Can I take this if I'm pregnant or breastfeeding?
No. The ingredients either have insufficient safety data or advise against use during pregnancy and breastfeeding. Talk with your doctor or pharmacist about whether this product is right for you if you're pregnant, trying to conceive, or nursing.
Does creatine cause water retention?
Yes, creatine commonly causes mild water retention. In one trial of patients with Lou Gehrig's disease taking a high dose, about one in four reported noticeable swelling after two months, though this lessened over time.
Is this safe for my kidneys?
Creatine is generally well tolerated in healthy adults, but it should be used carefully if you have kidney disease. Inosine in this formula also raises uric acid and has caused kidney stones in some people, especially at higher doses. If you have any kidney concerns, talk to your doctor or pharmacist first.
What does Beta-Alanine do?
Beta-Alanine is rated Possibly Effective for athletic and physical performance — it may help with muscle endurance during exercise. The tingling you might feel has no effect on how it works.
Will this help me build muscle?
The creatine in this product is Possibly Effective for muscle strength and athletic performance. It's not a shortcut — you still need training — but the evidence suggests it can help support your efforts.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Creamean Watermelon Rush is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Creamean Watermelon Rush label
Go deeper

The Full Monographs Behind Creamean Watermelon Rush’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Beta-alanine

Beta-alanine is an amino acid taken mostly by athletes to raise muscle carnosine, which may help buffer acid and reduce fatigue during short, high-intensity exercise. The evidence is moderat...

Read the full Beta-alanine monograph → Herb & supplement monograph

Taurine

Interacts with 173 drugs

Taurine is an amino acid your body makes naturally and that you also get from animal foods. It is widely used in energy drinks and sports supplements, and short-term use appears generally sa...

Read the full Taurine monograph → Herb & supplement monograph

Inosine

Interacts with 9 drugs

Inosine is a nucleoside (a building block of DNA and RNA) that the body makes on its own and is also sold as a supplement, mostly marketed for athletic performance. Solid evidence that it bo...

Read the full Inosine monograph → Herb & supplement monograph

Creatine

Creatine is one of the most studied sports supplements, with solid evidence that it can boost strength and performance during short, high-intensity activities like weightlifting and sprintin...

Read the full Creatine monograph → Herb & supplement monograph

Adenosine

Interacts with 47 drugs

Adenosine is a natural building block your body uses for energy and cell signaling, and a prescription injectable version is used by doctors to treat certain fast heart rhythms. As an over-t...

Read the full Adenosine monograph →
Sources

Sources & How We Checked

Creamean Watermelon Rush's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 137 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Beta-alanine 13 references
  1. Harris RC, Tallon MJ, Dunnett M, et al. The absorption of orally supplied beta-alanine and its effect on muscle carnosine synthesis in human vastus lateralis. Amino Acids 2006;30:279-89.
  2. Hill CA, Harris RC, Kim HJ, et al. Influence of beta-alanine supplementation on skeletal muscle carnosine concentrations and high intensity cycling capacity. Amino Acids 2007;32:225-33.
  3. Bellinger PM, Minahan CL. The effect of ß-alanine supplementation on cycling time trials of different length. Eur J Sport Sci 2016;16(7):829-36.
  4. Chung W, Shaw G, Anderson ME, et al. Effect of 10 week beta-alanine supplementation on competition and training performance in elite swimmers. Nutrients 2012;4(10):1441-53. PubMed
  5. Glenn JM, Gray M, Stewart R, et al. Incremental effects of 28 days of beta-alanine supplementation on high-intensity cycling performance and blood lactate in masters female cyclists. Amino Acids 2015;47(12):2593-600. PubMed
  6. Gross M, Bieri K, Hoppeler H, Norman B, Vogt M. Beta-alanine supplementation improves jumping power and affects severe-intensity performance in professional alpine skiers. Int J Sport Nutr Exerc Metab 2014;24(6):665-73. PubMed
  7. Howe ST, Bellinger PM, Driller MW, Shing CM, Fell JW. The effect of beta-alanine supplementation on isokinetic force and cycling performance in highly trained cyclists. Int J Sport Nutr Exerc Metab 2013;23(6):562-70. PubMed
  8. Sweeney KM, Wright GA, Glenn Brice A, Doberstein ST. The effect of beta-alanine supplementation on power performance during repeated sprint activity. J Strength Cond Res 2010;24(1):79-87.
  9. Décombaz J, Beaumont M, Vuichoud J, Bouisset F, Stellingwerff T. Effect of slow-release ß-alanine tablets on absorption kinetics and paresthesia. Amino Acids 2012;43(1):67-76. Erratum in: Amino Acids 2013;45(4):1015.
  10. Stellingwerff T, Anwander H, Egger A, et al. Effect of two ß-alanine dosing protocols on muscle carnosine synthesis and washout. Amino Acids 2012;42(6):2461-72. PubMed
  11. da Silva RP, de Oliveira LF, Saunders B, et al. Effects of ß-alanine and sodium bicarbonate supplementation on the estimated energy system contribution during high-intensity intermittent exercise. Amino Acids. 2019;51(1):83-96. PubMed
  12. Varanoske AN, Hoffman JR, Church DD, et al. Comparison of sustained-release and rapid-release ß-alanine formulations on changes in skeletal muscle carnosine and histidine content and isometric performance following a muscle-damaging protocol. Amino Acids. PubMed
  13. Perim P, Gobbi N, Duarte B, et al. Beta-alanine did not improve high-intensity performance throughout simulated road cycling. Eur J Sport Sci 2021. PubMed

See these in context on the Beta-alanine monograph →

Taurine 21 references
  1. Ahmad S, Robertson HT, Golper TA, et al. Multicenter trial of L-carnitine in maintenance hemodialysis patients. II. Clinical and biochemical effects. Kidney Int 1990;38:912-8. PubMed
  2. Machado-Vieira R, Viale CI, Kapczinski F. Mania associated with an energy drink: the possible role of caffeine, taurine, and inositol. Can J Psychiatry 2001;46:454-5. PubMed
  3. Obermann M, Schorn CF, Mummel P, et al. Taurine induced toxic encephalopathy? Clin Neurol Neurosurg 2006;108:812-3. PubMed
  4. Bichler, A., Swenson, A., and Harris, M. A. A combination of caffeine and taurine has no effect on short term memory but induces changes in heart rate and mean arterial blood pressure. Amino Acids 2006;31(4):471-476. PubMed
  5. Iyadurai, S. J. and Chung, S. S. New-onset seizures in adults: possible association with consumption of popular energy drinks. Epilepsy Behav 2007;10(3):504-508. PubMed
  6. Berger, A. J. and Alford, K. Cardiac arrest in a young man following excess consumption of caffeinated "energy drinks". Med J Aust. 1-5-2009;190(1):41-43. PubMed
  7. Worthley, M. I., Prabhu, A., De, Sciscio P., Schultz, C., Sanders, P., and Willoughby, S. R. Detrimental effects of energy drink consumption on platelet and endothelial function. Am J Med 2010;123(2):184-187. PubMed
  8. Morchon, Simon D. and Perez Castrillon, J. L. [Hypoglycemia by intake of taurine]. Rev.Clin Esp. 2010;210(1):49.
  9. Livshits, Z., Hoffman, R. S., Hymes, K. B., and Nelson, L. S. If vitamins could kill: massive hemolysis following naturopathic vitamin infusion. J Med Toxicol. 2011;7(3):224-226. PubMed
  10. Schoffl, I., Kothmann, J. F., Schoffl, V., Rupprecht, H. D., and Rupprecht, T. "Vodka energy": too much for the adolescent nephron? Pediatrics 2011;128(1):e227-e231. PubMed
  11. Calabro, R. S., Italiano, D., Gervasi, G., and Bramanti, P. Single tonic-clonic seizure after energy drink abuse. Epilepsy Behav 2012;23(3):384-385. PubMed
  12. Fujita, T., Ando, K., Noda, H., Ito, Y., and Sato, Y. Effects of increased adrenomedullary activity and taurine in young patients with borderline hypertension. Circulation 1987;75(3):525-532. PubMed
  13. Darling, P. B., Lepage, G., Leroy, C., Masson, P., and Roy, C. C. Effect of taurine supplements on fat absorption in cystic fibrosis. Pediatr Res 1985;19(6):578-582. PubMed
  14. Fukuyama, Y. and Ochiai, Y. Therapeutic trial by taurine for intractable childhood epilepsies. Brain Dev. 1982;4(1):63-69. PubMed
  15. Franconi, F., Bennardini, F., Mattana, A., Miceli, M., Ciuti, M., Mian, M., Gironi, A., Anichini, R., and Seghieri, G. Plasma and platelet taurine are reduced in subjects with insulin-dependent diabetes mellitus: effects of taurine supplementation. Am.J. DOI
  16. Stohs SJ, Miller M. A case study involving allergic reactions to sulfur-containing compounds including, sulfite, taurine, acesulfame potassium and sulfonamides. Food Chem Toxicol. 2014 Jan;63:240-3. PubMed
  17. Sun Q, Wang B, Li Y, Sun F, et al. Taurine supplementation lowers blood pressure and improves vascular function in prehypertension: randomized, double-blind, placebo-controlled study. Hypertension 2016 Mar;67(3):541-9. PubMed
  18. Jang ES, Hwang SH, Kim JW, Jeong SH. Effectiveness of 4-week oral taurine treatment for muscle cramps in patients with liver cirrhosis: a single-arm pilot study. Yonsei Med J 2021;62(1):21-8. PubMed
  19. Guan L, Miao P. The effects of taurine supplementation on obesity, blood pressure and lipid profile: A meta-analysis of randomized controlled trials. Eur J Pharmacol 2020;885:173533. PubMed
  20. Higgins JP, Liras GN, Liras IN, et al. Energy Drink Effects on Hemodynamics and Endothelial Function in Young Adults. Cardiology. 2021;146(2):258-262. PubMed
  21. Pallangyo P, Bhalia SV, Komba M, et al. Acute Myocardial Infarction Following the Consumption of Energy Drink in a 28-Year-Old Male: A Case Report. J Investig Med High Impact Case Rep. 2023 Jan-Dec;11:23247096231168811. PubMed

See these in context on the Taurine monograph →

Inosine 7 references
  1. Parkinson Study Group SURE-PD Investigators. Inosine to increase serum and cerebrospinal fluid urate in Parkinson disease: a randomized clinical trial. JAMA Neurol. 2014;71(2):141-50.
  2. Muñoz García D, Midaglia L, Martinez Vilela J, et al. Associated inosine to interferon: results of a clinical trial in multiple sclerosis. Acta Neurol Scand. 2015;131(6):405-10. PubMed
  3. Gonsette RE, Sindic C, D'hooghe MB, et al. Boosting endogenous neuroprotection in multiple sclerosis: The association of inosine and interferon beta in relapsing-remitting Multiple Sclerosis (ASIIMS) trial. Mult Scler. 2010;16(4):455-62.
  4. Markowitz CE, Spitsin S, Zimmerman V, et al. The treatment of multiple sclerosis with inosine. J Altern Complement Med. 2009;15(6):619-25. PubMed
  5. Watanabe H, Hattori T, Kume A, et al. Improved Parkinsons disease motor score in a single-arm open-label trial of febuxostat and inosine. Medicine (Baltimore) 2020;99(35):e21576. PubMed
  6. Parkinson Study Group SURE-PD3 Investigators, Schwarzschild MA, Ascherio A, et al. Effect of Urate-Elevating Inosine on Early Parkinson Disease Progression: The SURE-PD3 Randomized Clinical Trial. JAMA 2021;326(10):926-939.
  7. Walk D, Nicholson K, Locatelli E, et al. Randomized trial of inosine for urate elevation in amyotrophic lateral sclerosis. Muscle Nerve 2023;67(5):378-386. PubMed

See these in context on the Inosine monograph →

Creatine 86 references
  1. Koshy KM, Griswold E, Schneeberger EE. Interstitial nephritis in a patient taking creatine. N Engl J Med 1999;340:814-5. PubMed
  2. Vahedi K, Domingo V, Amarenco P, Bousser MG. Ischemic stroke in a sportsman who consumed MaHuang extract and creatine monohydrate for bodybuilding. J Neurol Neurosurg Psychiatr 2000;68:112-3.
  3. Greenhaff P. Renal dysfunction accompanying oral creatine supplements. Lancet 1998;352:233-4. PubMed
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