Curing Pills Ingredients & Drug Interactions
by Plum Flower
What is this page for?
First and foremost: checking Curing Pills against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Curing Pills is a dietary supplement by Plum Flower with 15 active ingredients. Its ingredients are commonly taken for fluid retention and swelling, digestive complaints, sleep and calming support.Based on those ingredients, 1,274 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Atractylodes lancea rhizome extract, Citrus reticulata exocarp extract, Pueraria lobata root extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Curing Pills by Plum Flower
Ask about any prescription or over-the-counter medication and we check it for interactions with Curing Pills by Plum Flower — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Curing Pills by Plum Flower
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
Curing Pills contains 15 ingredients total, including a proprietary extract blend and 14 individual botanical extracts. The active ingredients are Poria mushroom, Job's tears, Pogostemon cablin, Magnolia bark, Angelica dahurica root, Atractylodes rhizome, Costus root, Kudzu root, Setaria millet fruit, Trichosanthes root, Chrysanthemum flower, Tangerine peel, Gastrodia rhizome, and Japanese mint — traditional Chinese herbs used in formulas to support digestive function and overall wellness.
The product also contains three inactive ingredients: hydrated magnesium silicate, activated charcoal, and china wax, which serve as tablet binders and coating materials.
Does it work?
Moderate evidence
The evidence for most of Curing Pills' ingredients is not well established. Magnolia bark is possibly effective for gingivitis, but for the other conditions these herbs are used for — including low blood sugar (hypoglycemia), chronic fatigue, diarrhea, and common cold — the data we hold shows insufficient reliable evidence to rate their benefit.
Kudzu root is possibly effective for alcohol use disorder, but for hay fever, angina, and back pain, evidence is insufficient. No effectiveness ratings are available in our data for Poria mushroom, Costus, Chrysanthemum, Japanese mint, or several other ingredients.
How safe is it?
Well-documented data
Most of these herbs are generally well tolerated when used short-term in traditional preparations, but human safety data are limited for many of them. Magnolia bark may be okay for some adults in the short term, though concentrated extracts carry more uncertainty.
The main reported adverse effects are rare allergic reactions (including allergic rhinitis, asthma, and contact dermatitis), along with occasional reports of dry mouth, nausea, or in one trial, sexual dysfunction and numbness — though these were from combination products and it's unclear which ingredient was responsible. Japanese mint oil, if concentrated or inhaled, can trigger bronchial spasm or asthma-like symptoms, especially in children.
Regarding pregnancy and breastfeeding: Magnolia bark is unsafe in pregnancy, and Kudzu, Job's tears, Atractylodes, Costus, and Chrysanthemum are best avoided during pregnancy due to insufficient safety data or traditional concerns. Breastfeeding safety data are also limited or absent for most ingredients — Japanese mint oil should be kept away from the chest area while nursing.
Talk with your pharmacist or doctor before using this product if you're pregnant or nursing.
Meds to double-check
Moderate interaction found
Before taking Curing Pills, check if you're using any blood thinners or antiplatelet drugs (such as warfarin or clopidogrel), diabetes medications, sedatives (such as benzodiazepines), theophylline (a breathing medication), dextromethorphan (a cough suppressant), diltiazem or other blood pressure medications, methotrexate, tamoxifen, estrogen therapy, or caffeine supplements. We could not check six of the ingredients in this product — Massa fermenta, Pogostemon cablin, Angelica dahurica, Setaria italica, Trichosanthes kirilowii, and Gastrodia elata — so interactions with those may exist but are not documented in our data.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.
Curing Pills is a traditional herbal blend with limited human evidence for its claimed benefits and some meaningful interactions with prescription and over-the-counter medications. If you take blood thinners, diabetes drugs, sedatives, methotrexate, tamoxifen, estrogen therapy, caffeine supplements, or theophylline, check your exact medications using the tool on this page before starting.
Pregnant or nursing people should speak with their pharmacist or doctor first.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 11 of 15 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jul 23, 2020.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Curing Pills, straight from the product label.
| Brand | Plum Flower |
|---|---|
| Net contents | 10 Single Serve Packet(s); 0.42 Ounce(s); 11.85 Gram(s) |
| Market status | On market |
| Date entered into DSLD | Jul 23, 2020 |
| DSLD ID | 229555 |
| Product type | Botanical |
| Supplement form | Tablet Or Pill |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Curing Pills by Plum Flower, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Proprietary Extract Blend | 1185 mg | -- |
| Massa fermenta extract | 0 NP | -- |
| Poria cocos sclerotium extract | 0 NP | -- |
| Coix lacryma jobi extract | 0 NP | -- |
| Pogostemon cablin herb extract | 0 NP | -- |
| Magnolia officinalis bark extract | 0 NP | -- |
| Angelica dahurica root extract | 0 NP | -- |
| Atractylodes lancea rhizome extract | 0 NP | -- |
| Aucklandia lappa extract | 0 NP | -- |
| Pueraria lobata root extract | 0 NP | -- |
| Setaria italica fruit extract | 0 NP | -- |
| Trichosanthes kirilowii root extract | 0 NP | -- |
| Chrysanthemum morifolium flower extract | 0 NP | -- |
| Citrus reticulata exocarp extract | 0 NP | -- |
| Gastrodia elata rhizome extract | 0 NP | -- |
| Mentha haplocalyx herb extract | 0 NP | -- |
Other ingredients: hydrated Magnesium Silicate, activated Carbon, China Wax
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation
GMP Quality
Traditional herbal formula for healthy digestive system function
No Pharmaceuticals or dyes Unsulfured, preservative-free herbs when available
Scientifically authenticated herbs Microbial and heavy metal tested Produced at a good manufacturing practices (GMP) certified factory
General Statements
Loose pills (not encapsulated)
Used for decades by acupuncturists & herbalists around the world for settling the stomach
US owned & operated since 1969 Made in China
FDA Statement of Identity
Herbal Dietary Supplement
Seals/Symbols
cGMP Compliant Made in a cGMP certified facility
Suggested/Recommended/Usage/Directions
Take 1 packet 3 times daily or as directed by your health care practitioner
Precautions
Caution during pregnancy
Contains wheat and tree nuts
Keep out of reach of children
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Curing Pills by Plum Flower label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Curing Pills by Plum Flower
These are the 15 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Packet(s) Dosage formTablet Or Pill Servings per container10 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Proprietary Extract Blend
- › Massa fermenta extract
- › Poria cocos sclerotium extract
- › Coix lacryma jobi extract
- › Pogostemon cablin herb extract
- › Magnolia officinalis bark extract
- › Angelica dahurica root extract
- › Atractylodes lancea rhizome extract
- › Aucklandia lappa extract
- › Pueraria lobata root extract
- › Setaria italica fruit extract
- › Trichosanthes kirilowii root extract
- › Chrysanthemum morifolium flower extract
- › Citrus reticulata exocarp extract
- › Gastrodia elata rhizome extract
- › Mentha haplocalyx herb extract
Other (inactive) ingredients: Hydrated Magnesium Silicate, Activated Carbon, China Wax. These complete the product’s ingredient list but are not active constituents.
Curing Pills by Plum Flower Drug Interactions
HelloPharmacist Interaction Report
Curing Pills by Plum Flower contains 15 ingredients, of which 9 have been checked for drug interactions.
Altogether, these interactions span 1,253 individual medications. The product's most serious documented interaction is Moderate in severity, involving multiple ingredients and drug types.
Read the full breakdown — every affected drug type, severity by severity
Poria mushroom extract may enhance the effects of sedatives (CNS depressants) and theoretically alter how anticholinergic and cholinergic drugs work — these effects have been shown only in animals so far. Job's tears extract may enhance absorption of several medications, including theophylline (a breathing medication), dextromethorphan (a cough suppressant), chlorzoxazone (a muscle relaxant), and diltiazem (a blood pressure medication), potentially raising their levels in your blood.
Magnolia bark extract might add to the drowsy effects of sedatives and may increase bleeding risk if you're on blood thinners (anticoagulants) or antiplatelet drugs.
Atractylodes may increase bleeding risk with blood thinners or antiplatelet drugs, might affect aromatase inhibitors (used for certain cancers), and could theoretically change how your liver breaks down other medications — including some at Minor severity. Kudzu root extract carries Moderate interactions with blood thinners, cancer drugs like tamoxifen, methotrexate (an immunosuppressant), estrogen therapy, caffeine, and diabetes medications.
Tangerine extract may slightly affect how your body processes midazolam (a sedative), though human evidence is limited. We could not check Massa fermenta extract, Pogostemon cablin, Angelica dahurica, Setaria italica, Trichosanthes kirilowii, or Gastrodia elata — we hold no data for these ingredients.
Use the medication checker below with your exact drugs before starting this product.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Curing Pills?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Curing Pills interact with 1,274 drugs. Click any drug to see the details.
8 of the 15 ingredients in Curing Pills interact with drugs. Each result below shows which ingredient is responsible. Atractylodes lancea rhizome extract Citrus reticulata exocarp extract Pueraria lobata root extract Poria cocos sclerotium extract Magnolia officinalis bark extract Angelica dahurica root extract Coix lacryma jobi extract Trichosanthes kirilowii root extract
Acetaminophen, MeperidineDemerol APAP
How Acetaminophen, Meperidine interacts with Curing Pills — through 5 ingredients. Tap an ingredient for the detail:
Magnolia Officinalis Bark ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of large doses of magnolia bark and CNS depressants might have additive effects.
Read the full Magnolia Officinalis Bark Extract + Acetaminophen, Meperidine interactionPueraria Lobata Root ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive hepatotoxic effects.
Read the full Pueraria Lobata Root Extract + Acetaminophen, Meperidine interactionPoria Cocos Sclerotium ExtractCns Depressants Moderate
Interaction Summary
Theoretically, taking poria mushroom extract may enhance the therapeutic and adverse effects of sedatives.
Read the full Poria Cocos Sclerotium Extract + Acetaminophen, Meperidine interactionAngelica Dahurica Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
In vitro research shows that ashitaba extract inhibits cytochrome P450 (CYP) 1A2.
Read the full Angelica Dahurica Root Extract + Acetaminophen, Meperidine interactionAtractylodes Lancea Rhizome ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, atractylodes might decrease the levels of CYP1A2 substrates.
Read the full Atractylodes Lancea Rhizome Extract + Acetaminophen, Meperidine interactionAcetaminophen, MethocarbamolRobaxacet
How Acetaminophen, Methocarbamol interacts with Curing Pills — through 3 ingredients. Tap an ingredient for the detail:
Angelica Dahurica Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
In vitro research shows that ashitaba extract inhibits cytochrome P450 (CYP) 1A2.
Read the full Angelica Dahurica Root Extract + Acetaminophen, Methocarbamol interactionPueraria Lobata Root ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive hepatotoxic effects.
Read the full Pueraria Lobata Root Extract + Acetaminophen, Methocarbamol interactionAtractylodes Lancea Rhizome ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, atractylodes might decrease the levels of CYP1A2 substrates.
Read the full Atractylodes Lancea Rhizome Extract + Acetaminophen, Methocarbamol interactionAcetaminophen, OrphenadrineOrfenagesic
How Acetaminophen, Orphenadrine interacts with Curing Pills — through 3 ingredients. Tap an ingredient for the detail:
Pueraria Lobata Root ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive hepatotoxic effects.
Read the full Pueraria Lobata Root Extract + Acetaminophen, Orphenadrine interactionAngelica Dahurica Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
In vitro research shows that ashitaba extract inhibits cytochrome P450 (CYP) 1A2.
Read the full Angelica Dahurica Root Extract + Acetaminophen, Orphenadrine interactionAtractylodes Lancea Rhizome ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, atractylodes might decrease the levels of CYP1A2 substrates.
Read the full Atractylodes Lancea Rhizome Extract + Acetaminophen, Orphenadrine interactionAcetaminophen, OxycodonePercocet, Roxicet, Tylox, Xartemis XR
How Acetaminophen, Oxycodone interacts with Curing Pills — through 5 ingredients. Tap an ingredient for the detail:
Angelica Dahurica Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
In vitro research shows that ashitaba extract inhibits cytochrome P450 (CYP) 1A2.
Read the full Angelica Dahurica Root Extract + Acetaminophen, Oxycodone interactionPueraria Lobata Root ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive hepatotoxic effects.
Read the full Pueraria Lobata Root Extract + Acetaminophen, Oxycodone interactionPoria Cocos Sclerotium ExtractCns Depressants Moderate
Interaction Summary
Theoretically, taking poria mushroom extract may enhance the therapeutic and adverse effects of sedatives.
Read the full Poria Cocos Sclerotium Extract + Acetaminophen, Oxycodone interactionMagnolia Officinalis Bark ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of large doses of magnolia bark and CNS depressants might have additive effects.
Read the full Magnolia Officinalis Bark Extract + Acetaminophen, Oxycodone interactionAtractylodes Lancea Rhizome ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, atractylodes might decrease the levels of CYP1A2 substrates.
Read the full Atractylodes Lancea Rhizome Extract + Acetaminophen, Oxycodone interactionAcetaminophen, Pamabrom, PyrilamineMidol Max Strength PMS, Pamprin, Pamprin ES
How Acetaminophen, Pamabrom, Pyrilamine interacts with Curing Pills — through 4 ingredients. Tap an ingredient for the detail:
Pueraria Lobata Root ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive hepatotoxic effects.
Read the full Pueraria Lobata Root Extract + Acetaminophen, Pamabrom, Pyrilamine interactionPoria Cocos Sclerotium ExtractAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, poria mushroom might decrease the clinical effects of anticholinergic drugs.
Read the full Poria Cocos Sclerotium Extract + Acetaminophen, Pamabrom, Pyrilamine interactionAngelica Dahurica Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
In vitro research shows that ashitaba extract inhibits cytochrome P450 (CYP) 1A2.
Read the full Angelica Dahurica Root Extract + Acetaminophen, Pamabrom, Pyrilamine interactionAtractylodes Lancea Rhizome ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, atractylodes might decrease the levels of CYP1A2 substrates.
Read the full Atractylodes Lancea Rhizome Extract + Acetaminophen, Pamabrom, Pyrilamine interactionAcetaminophen, PentazocineTalacen
How Acetaminophen, Pentazocine interacts with Curing Pills — through 5 ingredients. Tap an ingredient for the detail:
Angelica Dahurica Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
In vitro research shows that ashitaba extract inhibits cytochrome P450 (CYP) 1A2.
Read the full Angelica Dahurica Root Extract + Acetaminophen, Pentazocine interactionPueraria Lobata Root ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive hepatotoxic effects.
Read the full Pueraria Lobata Root Extract + Acetaminophen, Pentazocine interactionMagnolia Officinalis Bark ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of large doses of magnolia bark and CNS depressants might have additive effects.
Read the full Magnolia Officinalis Bark Extract + Acetaminophen, Pentazocine interactionPoria Cocos Sclerotium ExtractCns Depressants Moderate
Interaction Summary
Theoretically, taking poria mushroom extract may enhance the therapeutic and adverse effects of sedatives.
Read the full Poria Cocos Sclerotium Extract + Acetaminophen, Pentazocine interactionAtractylodes Lancea Rhizome ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, atractylodes might decrease the levels of CYP1A2 substrates.
Read the full Atractylodes Lancea Rhizome Extract + Acetaminophen, Pentazocine interactionAcetaminophen, Phenylephrine, ChlorpheniramineSuper Cold Tabs
How Acetaminophen, Phenylephrine, Chlorpheniramine interacts with Curing Pills — through 5 ingredients. Tap an ingredient for the detail:
Pueraria Lobata Root ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive hepatotoxic effects.
Read the full Pueraria Lobata Root Extract + Acetaminophen, Phenylephrine, Chlorpheniramine interactionPoria Cocos Sclerotium ExtractAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, poria mushroom might decrease the clinical effects of anticholinergic drugs.
Read the full Poria Cocos Sclerotium Extract + Acetaminophen, Phenylephrine, Chlorpheniramine interactionAngelica Dahurica Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
In vitro research shows that ashitaba extract inhibits cytochrome P450 (CYP) 1A2.
Read the full Angelica Dahurica Root Extract + Acetaminophen, Phenylephrine, Chlorpheniramine interactionAtractylodes Lancea Rhizome ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, atractylodes might decrease the levels of CYP1A2 substrates.
Read the full Atractylodes Lancea Rhizome Extract + Acetaminophen, Phenylephrine, Chlorpheniramine interactionCitrus Reticulata Exocarp ExtractCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
In vitro, tangeretin, a constituent of tangerine, induces a 52% increase in the metabolism of midazolam by cytochrome P450 3A4 (CYP3A4).
Read the full Citrus Reticulata Exocarp Extract + Acetaminophen, Phenylephrine, Chlorpheniramine interactionAcetaminophen, PhenylpropanolamineTetra Caps
How Acetaminophen, Phenylpropanolamine interacts with Curing Pills — through 3 ingredients. Tap an ingredient for the detail:
Angelica Dahurica Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
In vitro research shows that ashitaba extract inhibits cytochrome P450 (CYP) 1A2.
Read the full Angelica Dahurica Root Extract + Acetaminophen, Phenylpropanolamine interactionPueraria Lobata Root ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive hepatotoxic effects.
Read the full Pueraria Lobata Root Extract + Acetaminophen, Phenylpropanolamine interactionAtractylodes Lancea Rhizome ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, atractylodes might decrease the levels of CYP1A2 substrates.
Read the full Atractylodes Lancea Rhizome Extract + Acetaminophen, Phenylpropanolamine interactionAcetaminophen, Phenylpropanolamine, PhenyltoloxamineSinubid
How Acetaminophen, Phenylpropanolamine, Phenyltoloxamine interacts with Curing Pills — through 3 ingredients. Tap an ingredient for the detail:
Pueraria Lobata Root ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive hepatotoxic effects.
Read the full Pueraria Lobata Root Extract + Acetaminophen, Phenylpropanolamine, Phenyltoloxamine interactionAngelica Dahurica Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
In vitro research shows that ashitaba extract inhibits cytochrome P450 (CYP) 1A2.
Read the full Angelica Dahurica Root Extract + Acetaminophen, Phenylpropanolamine, Phenyltoloxamine interactionAtractylodes Lancea Rhizome ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, atractylodes might decrease the levels of CYP1A2 substrates.
Read the full Atractylodes Lancea Rhizome Extract + Acetaminophen, Phenylpropanolamine, Phenyltoloxamine interactionAcetaminophen, PhenyltoloxaminePercogesic, Relagesic
How Acetaminophen, Phenyltoloxamine interacts with Curing Pills — through 3 ingredients. Tap an ingredient for the detail:
Angelica Dahurica Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
In vitro research shows that ashitaba extract inhibits cytochrome P450 (CYP) 1A2.
Read the full Angelica Dahurica Root Extract + Acetaminophen, Phenyltoloxamine interactionPueraria Lobata Root ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive hepatotoxic effects.
Read the full Pueraria Lobata Root Extract + Acetaminophen, Phenyltoloxamine interactionAtractylodes Lancea Rhizome ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, atractylodes might decrease the levels of CYP1A2 substrates.
Read the full Atractylodes Lancea Rhizome Extract + Acetaminophen, Phenyltoloxamine interactionAcetaminophen, Phenyltoloxamine, SalicylamideLobac
How Acetaminophen, Phenyltoloxamine, Salicylamide interacts with Curing Pills — through 3 ingredients. Tap an ingredient for the detail:
Pueraria Lobata Root ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive hepatotoxic effects.
Read the full Pueraria Lobata Root Extract + Acetaminophen, Phenyltoloxamine, Salicylamide interactionAngelica Dahurica Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
In vitro research shows that ashitaba extract inhibits cytochrome P450 (CYP) 1A2.
Read the full Angelica Dahurica Root Extract + Acetaminophen, Phenyltoloxamine, Salicylamide interactionAtractylodes Lancea Rhizome ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, atractylodes might decrease the levels of CYP1A2 substrates.
Read the full Atractylodes Lancea Rhizome Extract + Acetaminophen, Phenyltoloxamine, Salicylamide interactionAcetaminophen, PropoxypheneDarvocet-N 100, Darvocet-N 50, E-Lor, Wygesic
How Acetaminophen, Propoxyphene interacts with Curing Pills — through 5 ingredients. Tap an ingredient for the detail:
Angelica Dahurica Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
In vitro research shows that ashitaba extract inhibits cytochrome P450 (CYP) 1A2.
Read the full Angelica Dahurica Root Extract + Acetaminophen, Propoxyphene interactionPueraria Lobata Root ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive hepatotoxic effects.
Read the full Pueraria Lobata Root Extract + Acetaminophen, Propoxyphene interactionMagnolia Officinalis Bark ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of large doses of magnolia bark and CNS depressants might have additive effects.
Read the full Magnolia Officinalis Bark Extract + Acetaminophen, Propoxyphene interactionPoria Cocos Sclerotium ExtractCns Depressants Moderate
Interaction Summary
Theoretically, taking poria mushroom extract may enhance the therapeutic and adverse effects of sedatives.
Read the full Poria Cocos Sclerotium Extract + Acetaminophen, Propoxyphene interactionAtractylodes Lancea Rhizome ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, atractylodes might decrease the levels of CYP1A2 substrates.
Read the full Atractylodes Lancea Rhizome Extract + Acetaminophen, Propoxyphene interactionAcetaminophen, PseudoephedrineChildren's Tylenol Sinus, Dristan N.D., Non-Aspirin Sinus, Ornex, Ornex-Max, Sinutab +5 more
How Acetaminophen, Pseudoephedrine interacts with Curing Pills — through 3 ingredients. Tap an ingredient for the detail:
Pueraria Lobata Root ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive hepatotoxic effects.
Read the full Pueraria Lobata Root Extract + Acetaminophen, Pseudoephedrine interactionAngelica Dahurica Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
In vitro research shows that ashitaba extract inhibits cytochrome P450 (CYP) 1A2.
Read the full Angelica Dahurica Root Extract + Acetaminophen, Pseudoephedrine interactionAtractylodes Lancea Rhizome ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, atractylodes might decrease the levels of CYP1A2 substrates.
Read the full Atractylodes Lancea Rhizome Extract + Acetaminophen, Pseudoephedrine interactionAcetaminophen, Pseudoephedrine, TriprolidineActifed Plus ES
How Acetaminophen, Pseudoephedrine, Triprolidine interacts with Curing Pills — through 3 ingredients. Tap an ingredient for the detail:
Angelica Dahurica Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
In vitro research shows that ashitaba extract inhibits cytochrome P450 (CYP) 1A2.
Read the full Angelica Dahurica Root Extract + Acetaminophen, Pseudoephedrine, Triprolidine interactionPueraria Lobata Root ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive hepatotoxic effects.
Read the full Pueraria Lobata Root Extract + Acetaminophen, Pseudoephedrine, Triprolidine interactionAtractylodes Lancea Rhizome ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, atractylodes might decrease the levels of CYP1A2 substrates.
Read the full Atractylodes Lancea Rhizome Extract + Acetaminophen, Pseudoephedrine, Triprolidine interactionAcetazolamideAk-Zol, Diamox
How Acetazolamide interacts with Curing Pills — through 2 ingredients. Tap an ingredient for the detail:
Poria Cocos Sclerotium ExtractCns Depressants Moderate
Interaction Summary
Theoretically, taking poria mushroom extract may enhance the therapeutic and adverse effects of sedatives.
Read the full Poria Cocos Sclerotium Extract + Acetazolamide interactionMagnolia Officinalis Bark ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of large doses of magnolia bark and CNS depressants might have additive effects.
Read the full Magnolia Officinalis Bark Extract + Acetazolamide interactionAcetohexamideDymelor
How Acetohexamide interacts with Curing Pills — through 3 ingredients. Tap an ingredient for the detail:
Trichosanthes Kirilowii Root ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, concomitant use of Chinese cucumber with antidiabetic drugs may have additive effects and adverse effects.
Read the full Trichosanthes Kirilowii Root Extract + Acetohexamide interactionPueraria Lobata Root ExtractHepatotoxic Drugs, Antidiabetes Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive hepatotoxic effects.
Read the full Pueraria Lobata Root Extract + Acetohexamide interactionCoix Lacryma Jobi ExtractAntidiabetes Drugs Moderate
Interaction Summary
Preliminary evidence shows that constituents of Job's tears might have hypoglycemic effects.
Read the full Coix Lacryma Jobi Extract + Acetohexamide interactionAcetylcholineMiochol-E
How Acetylcholine interacts with Curing Pills — through 1 ingredient. Tap an ingredient for the detail:
Poria Cocos Sclerotium ExtractCholinergic Drugs Moderate
Interaction Summary
Theoretically, poria mushroom might have additive effects when used with cholinergic drugs.
Read the full Poria Cocos Sclerotium Extract + Acetylcholine interactionAcetylsalicylic AcidEntrophen
How Acetylsalicylic Acid interacts with Curing Pills — through 3 ingredients. Tap an ingredient for the detail:
Atractylodes Lancea Rhizome ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, atractylodes might increase the risk of bleeding when used concomitantly with anticoagulant and antiplatelet drugs.
Read the full Atractylodes Lancea Rhizome Extract + Acetylsalicylic Acid interactionMagnolia Officinalis Bark ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, magnolia might have additive effects and increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Read the full Magnolia Officinalis Bark Extract + Acetylsalicylic Acid interactionPueraria Lobata Root ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, kudzu may increase the risk of bleeding if used with antiplatelet or anticoagulant drugs.
Read the full Pueraria Lobata Root Extract + Acetylsalicylic Acid interactionAclidinium BromideTudorza Pressair
How Aclidinium Bromide interacts with Curing Pills — through 1 ingredient. Tap an ingredient for the detail:
Poria Cocos Sclerotium ExtractAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, poria mushroom might decrease the clinical effects of anticholinergic drugs.
Read the full Poria Cocos Sclerotium Extract + Aclidinium Bromide interactionAclidinium Bromide, Formoterol Fumarate DihydrateDuaklir Pressair
How Aclidinium Bromide, Formoterol Fumarate Dihydrate interacts with Curing Pills — through 1 ingredient. Tap an ingredient for the detail:
Poria Cocos Sclerotium ExtractAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, poria mushroom might decrease the clinical effects of anticholinergic drugs.
Read the full Poria Cocos Sclerotium Extract + Aclidinium Bromide, Formoterol Fumarate Dihydrate interactionAdagrasibKrazati
How Adagrasib interacts with Curing Pills — through 3 ingredients. Tap an ingredient for the detail:
Pueraria Lobata Root ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive hepatotoxic effects.
Read the full Pueraria Lobata Root Extract + Adagrasib interactionCitrus Reticulata Exocarp ExtractCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
In vitro, tangeretin, a constituent of tangerine, induces a 52% increase in the metabolism of midazolam by cytochrome P450 3A4 (CYP3A4).
Read the full Citrus Reticulata Exocarp Extract + Adagrasib interactionAtractylodes Lancea Rhizome ExtractCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, atractylodes might increase the levels of CYP3A4 substrates.
Read the full Atractylodes Lancea Rhizome Extract + Adagrasib interactionAerosphere Budesonide, Formoterol Fumarate, GlycopyrrolateBreztri
How Aerosphere Budesonide, Formoterol Fumarate, Glycopyrrolate interacts with Curing Pills — through 1 ingredient. Tap an ingredient for the detail:
Poria Cocos Sclerotium ExtractAnticholinergic Drugs Moderate
Interaction Summary
Theoretically, poria mushroom might decrease the clinical effects of anticholinergic drugs.
Read the full Poria Cocos Sclerotium Extract + Aerosphere Budesonide, Formoterol Fumarate, Glycopyrrolate interactionAgomelatineValdoxan
How Agomelatine interacts with Curing Pills — through 2 ingredients. Tap an ingredient for the detail:
Angelica Dahurica Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
In vitro research shows that ashitaba extract inhibits cytochrome P450 (CYP) 1A2.
Read the full Angelica Dahurica Root Extract + Agomelatine interactionAtractylodes Lancea Rhizome ExtractCytochrome P450 1a2 (cyp1a2) Substrates Minor
Interaction Summary
Theoretically, atractylodes might decrease the levels of CYP1A2 substrates.
Read the full Atractylodes Lancea Rhizome Extract + Agomelatine interactionAlbiglutideTanzeum
How Albiglutide interacts with Curing Pills — through 3 ingredients. Tap an ingredient for the detail:
Coix Lacryma Jobi ExtractAntidiabetes Drugs Moderate
Interaction Summary
Preliminary evidence shows that constituents of Job's tears might have hypoglycemic effects.
Read the full Coix Lacryma Jobi Extract + Albiglutide interactionTrichosanthes Kirilowii Root ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, concomitant use of Chinese cucumber with antidiabetic drugs may have additive effects and adverse effects.
Read the full Trichosanthes Kirilowii Root Extract + Albiglutide interactionPueraria Lobata Root ExtractAntidiabetes Drugs Minor
Interaction Summary
Theoretically, taking kudzu with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Pueraria Lobata Root Extract + Albiglutide interactionAldesleukinProleukin
How Aldesleukin interacts with Curing Pills — through 1 ingredient. Tap an ingredient for the detail:
Pueraria Lobata Root ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive hepatotoxic effects.
Read the full Pueraria Lobata Root Extract + Aldesleukin interactionAlectinib HydrochlorideAlecensa
How Alectinib Hydrochloride interacts with Curing Pills — through 1 ingredient. Tap an ingredient for the detail:
Pueraria Lobata Root ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive hepatotoxic effects.
Read the full Pueraria Lobata Root Extract + Alectinib Hydrochloride interactionAlfentanilAlfenta
How Alfentanil interacts with Curing Pills — through 4 ingredients. Tap an ingredient for the detail:
Poria Cocos Sclerotium ExtractCns Depressants Moderate
Interaction Summary
Theoretically, taking poria mushroom extract may enhance the therapeutic and adverse effects of sedatives.
Read the full Poria Cocos Sclerotium Extract + Alfentanil interactionMagnolia Officinalis Bark ExtractCns Depressants Moderate
Interaction Summary
Theoretically, concomitant use of large doses of magnolia bark and CNS depressants might have additive effects.
Read the full Magnolia Officinalis Bark Extract + Alfentanil interactionCitrus Reticulata Exocarp ExtractCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
In vitro, tangeretin, a constituent of tangerine, induces a 52% increase in the metabolism of midazolam by cytochrome P450 3A4 (CYP3A4).
Read the full Citrus Reticulata Exocarp Extract + Alfentanil interactionAtractylodes Lancea Rhizome ExtractCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, atractylodes might increase the levels of CYP3A4 substrates.
Read the full Atractylodes Lancea Rhizome Extract + Alfentanil interactionAllopurinolCaplenal, Cosuric, Rimapurinol, Zyloprim, Zyloric
How Allopurinol interacts with Curing Pills — through 1 ingredient. Tap an ingredient for the detail:
Pueraria Lobata Root ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive hepatotoxic effects.
Read the full Pueraria Lobata Root Extract + Allopurinol interactionAlogliptinNesina
How Alogliptin interacts with Curing Pills — through 5 ingredients. Tap an ingredient for the detail:
Coix Lacryma Jobi ExtractAntidiabetes Drugs Moderate
Interaction Summary
Preliminary evidence shows that constituents of Job's tears might have hypoglycemic effects.
Read the full Coix Lacryma Jobi Extract + Alogliptin interactionPueraria Lobata Root ExtractHepatotoxic Drugs, Antidiabetes Drugs Moderate
Interaction Summary
Theoretically, concomitant use might have additive hepatotoxic effects.
Read the full Pueraria Lobata Root Extract + Alogliptin interactionTrichosanthes Kirilowii Root ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, concomitant use of Chinese cucumber with antidiabetic drugs may have additive effects and adverse effects.
Read the full Trichosanthes Kirilowii Root Extract + Alogliptin interactionAtractylodes Lancea Rhizome ExtractCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
Theoretically, atractylodes might increase the levels of CYP3A4 substrates.
Read the full Atractylodes Lancea Rhizome Extract + Alogliptin interactionCitrus Reticulata Exocarp ExtractCytochrome P450 3a4 (cyp3a4) Substrates Minor
Interaction Summary
In vitro, tangeretin, a constituent of tangerine, induces a 52% increase in the metabolism of midazolam by cytochrome P450 3A4 (CYP3A4).
Read the full Citrus Reticulata Exocarp Extract + Alogliptin interactionAlogliptin, MetforminKazano
How Alogliptin, Metformin interacts with Curing Pills — through 3 ingredients. Tap an ingredient for the detail:
Trichosanthes Kirilowii Root ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, concomitant use of Chinese cucumber with antidiabetic drugs may have additive effects and adverse effects.
Read the full Trichosanthes Kirilowii Root Extract + Alogliptin, Metformin interactionCoix Lacryma Jobi ExtractAntidiabetes Drugs Moderate
Interaction Summary
Preliminary evidence shows that constituents of Job's tears might have hypoglycemic effects.
Read the full Coix Lacryma Jobi Extract + Alogliptin, Metformin interactionPueraria Lobata Root ExtractAntidiabetes Drugs Minor
Interaction Summary
Theoretically, taking kudzu with antidiabetes drugs might increase the risk of hypoglycemia.
Read the full Pueraria Lobata Root Extract + Alogliptin, Metformin interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Curing Pills with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Atractylodes lancea rhizome extract
Anticoagulant/Antiplatelet Drugs
Theoretically, atractylodes might increase the risk of bleeding when used concomitantly with anticoagulant and antiplatelet drugs.
Laboratory research suggests that atractylenolides II and III, constituents of atractylodes, reduce platelet activation. So far, this has not been shown in humans.
Aromatase Inhibitors
Theoretically, atractylodes may have an additive effect when used with other aromatase inhibitors.
Laboratory research suggests that atractylodes and its constituents exhibit aromatase inhibitor effects.
Hexobarbital
Theoretically, taking atractylodes may prolong the therapeutic and adverse effects of hexobarbital.
In animals, atractylodes has been shown to prolong the effects of hexobarbital. These effects have not been shown in humans.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, atractylodes might decrease the levels of CYP1A2 substrates.
In animals, atractylodes administered at high doses has been shown to induce CYP1A2 activity. This effect has not been shown in humans.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, atractylodes might increase the levels of CYP3A4 substrates.
In animals, atractylodes administered at high doses has been shown to inhibit CYP3A1 activity, which is a homolog to the human CYP3A4 enzyme. This effect has not been shown in humans.
Citrus reticulata exocarp extract
Cytochrome P450 3A4 (Cyp3A4) Substrates
In vitro, tangeretin, a constituent of tangerine, induces a 52% increase in the metabolism of midazolam by cytochrome P450 3A4 (CYP3A4). This suggests that tangeretin may stimulate CYP3A4 activity. However, in humans, drinking tangerine juice 200 mL slightly delayed the absorption, but did not affect the metabolism, of midazolam, a CYP3A4 substrate. Theoretically, tangerine juice might increase CYP3A4 activity and decrease levels of drugs metabolized by this enzyme. However, this effect is unlikely.
Some drugs metabolized by CYP3A4 include amitriptyline (Elavil), amiodarone (Cordarone), citalopram (Celexa), felodipine (Plendil), lansoprazole (Prevacid), ondansetron (Zofran), prednisone (Deltasone, Orasone), sertraline (Zoloft), sibutramine (Meridia), and many others.
Midazolam (Versed)
In vitro, tangeretin, a constituent of tangerine, appears to increase the metabolism of midazolam in human liver microsomes by up to 52%. However, in humans, drinking tangerine juice 200 mL slightly delayed the absorption, but did not affect the metabolism, of midazolam. Theoretically, tangerine juice might increase the metabolism and reduce the effects of midazolam. However, this effect is unlikely.
Pueraria lobata root extract
Anticoagulant/Antiplatelet Drugs
Theoretically, kudzu may increase the risk of bleeding if used with antiplatelet or anticoagulant drugs.
Kudzu isoflavones are reported to have antiplatelet activity.
Caffeine
Theoretically, taking kudzu with caffeine might increase levels of caffeine.
In healthy males injected with the kudzu constituent puerarin, caffeine clearance and metabolism is inhibited. This effect has been attributed to inhibition of cytochrome P450 1A2 (CYP1A2) enzyme, which is involved in caffeine metabolism. It is unclear if taking kudzu orally would have this same effect.
Estrogens
Theoretically, kudzu might alter the effects of estrogen therapy.
Some research suggests that kudzu has estrogenic effects. This may enhance or inhibit the effects of estrogen therapy.
Hepatotoxic Drugs
Theoretically, concomitant use might have additive hepatotoxic effects.
There is some concern that kudzu can adversely affect the liver.
Methotrexate (Trexall, Others)
Theoretically, taking kudzu with methotrexate might increase the risk of methotrexate toxicity.
Preclinical research suggests that kudzu extract greatly reduces the elimination and increases the toxicity of methotrexate. Kudzu might inhibit organic anion transporters (OATs) that are responsible for hepatobiliary and renal excretion of anions, similar to the interaction between methotrexate and non-steroidal anti-inflammatory drugs (NSAIDs).
Tamoxifen (Nolvadex)
Theoretically, kudzu might interfere with tamoxifen activity.
Some research suggests that kudzu may have estrogenic effects.
Antidiabetes Drugs
Theoretically, taking kudzu with antidiabetes drugs might increase the risk of hypoglycemia.
Kudzu might lower blood glucose levels and have additive effects in patients treated with antidiabetic agents. The dose of diabetes medications might need to be adjusted.
Poria cocos sclerotium extract
Anticholinergic Drugs
Theoretically, poria mushroom might decrease the clinical effects of anticholinergic drugs.
In animal research, poria mushroom essential oil reduces acetylcholinesterase activity. This interaction has not been shown in humans.
Cholinergic Drugs
Theoretically, poria mushroom might have additive effects when used with cholinergic drugs.
In animal research, poria mushroom essential oil reduces acetylcholinesterase activity. This interaction has not been shown in humans.
Cns Depressants
Theoretically, taking poria mushroom extract may enhance the therapeutic and adverse effects of sedatives.
Animal research shows that poria mushroom extract has sedative properties. This interaction has not been shown in humans.
Magnolia officinalis bark extract
Anticoagulant/Antiplatelet Drugs
Theoretically, magnolia might have additive effects and increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
In vitro research shows that the chemicals magnolol and honokiol, isolated from magnolia bark, inhibit platelet aggregation that is experimentally induced by collagen and arachidonic acid. However, they do not inhibit platelet aggregation that is induced by adenosine diphosphate, platelet-activating factor, or thrombin. This interaction has not been reported in humans.
Cns Depressants
Theoretically, concomitant use of large doses of magnolia bark and CNS depressants might have additive effects.
In vitro and animal research shows that constituents extracted from magnolia bark, especially honokiol and magnolol, have sedative effects. These effects may be due to the inhibition of catecholamine release and modulation of gamma-aminobutyric acid-A (GABA-A) receptors.
Angelica dahurica root extract
Cytochrome P450 1A2 (Cyp1A2) Substrates
In vitro research shows that ashitaba extract inhibits cytochrome P450 (CYP) 1A2. Theoretically, concomitant use of ashitaba with CYP1A2 substrates might decrease the clearance of these substrates and increase the risk for adverse effects. However, this interaction has yet to be reported in humans. Until more is known, use with caution.
Coix lacryma jobi extract
Antidiabetes Drugs
Preliminary evidence shows that constituents of Job's tears might have hypoglycemic effects. Theoretically, concomitant use with drugs that decrease blood glucose levels might increase the risk of hypoglycemia. Some antidiabetes drugs include glimepiride (Amaryl), glyburide (DiaBeta, Glynase PresTab, Micronase), insulin, pioglitazone (Actos), rosiglitazone (Avandia), chlorpropamide (Diabinese), glipizide (Glucotrol), tolbutamide (Orinase), and others.
Chlorzoxazone (Parafon Forte, Paraflex)
Animal research suggests that Job's tears might enhance absorption of chlorzoxazone in the small intestine. Single dose and short-term oral administration of Job's tears bran ethanolic extract along with oral administration of a five-drug cocktail containing chlorzoxazone increases chlorzoxazone peak plasma concentration and area under the plasma concentration-time curve (AUC) without altering major cytochrome P450 activities in the liver. This effect has not been reported in humans.
Dextromethorphan (Robitussin Dm, Others)
Animal research suggests that Job's tears might enhance absorption of dextromethorphan in the small intestine. Single dose oral administration of Job's tears bran ethanolic extract along with oral administration of a five-drug cocktail containing dextromethorphan increases dextromethorphan area under the plasma concentration-time curve (AUC) without altering major cytochrome P450 activities in the liver. This effect has not been reported in humans.
Diltiazem (Cardizem, Others)
Animal research suggests that Job's tears might enhance absorption of diltiazem in the small intestine. Single dose oral administration of Job's tears bran ethanolic extract along with oral administration of a five-drug cocktail containing diltiazem increases diltiazem peak plasma concentration and area under the plasma concentration-time curve (AUC) without altering major cytochrome P450 activities in the liver. This effect has not been reported in humans.
Theophylline
Animal research suggests that Job's tears might enhance absorption of theophylline in the small intestine. Single dose and short-term oral administration of Job's tears bran ethanolic extract along with oral administration of a five-drug cocktail containing theophylline increases theophylline peak plasma concentration and area under the plasma concentration-time curve (AUC) without altering major cytochrome P450 activities in the liver. This effect has not been reported in humans.
Trichosanthes kirilowii root extract
Antidiabetes Drugs
Theoretically, concomitant use of Chinese cucumber with antidiabetic drugs may have additive effects and adverse effects. Monitor blood glucose levels closely, dose adjustment may be needed.
Brand information
Manufacturer and brand details for Curing Pills, from the product label.
Plum Flower
- Name
- Mayway Corp.
- City
- Oakland
- State
- CA
- ZipCode
- 94607
- Phone Number
- 1-800-262-9929
- Web Address
- www.plumflowerherbs.com
Curing Pills by Plum Flower: Common Questions
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Does Kudzu in this product actually help with alcohol cravings?
Are there any fillers or artificial ingredients in Curing Pills?
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Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Curing Pills’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Poria Mushroom
Interacts with 417 drugsPoria mushroom (Fu Ling) is a fungus long used in Traditional Chinese Medicine, mainly as a mild diuretic and digestive and calming aid. Modern scientific evidence in humans is very limited,...
Read the full Poria Mushroom monograph → Herb & supplement monographJob's Tears
Interacts with 128 drugsJob's Tears is a grain-like seed long used as a food and in traditional medicine, especially in East Asia. While it is generally safe as a food and is being studied for possible effects on m...
Read the full Job's Tears monograph → Herb & supplement monographMagnolia
Interacts with 351 drugsMagnolia bark and flower buds have a long history in traditional Chinese and Japanese medicine, often for stress, sleep, and digestion. Modern human research is still limited, so we can't be...
Read the full Magnolia monograph → Herb & supplement monographAshitaba
Interacts with 186 drugsAshitaba is a leafy plant from Japan that is eaten as a vegetable and taken as a supplement for general health, antioxidant, and heart benefits. Most of the supporting research comes from la...
Read the full Ashitaba monograph → Herb & supplement monographAtractylodes
Interacts with 801 drugsAtractylodes is a root used for centuries in traditional Chinese, Japanese, and Thai medicine, mostly for digestive complaints and fatigue, often as part of multi-herb formulas. Modern resea...
Read the full Atractylodes monograph → Herb & supplement monographCostus
Costus (Saussurea costus) is a root used in Ayurvedic, Unani, and traditional Chinese medicine, mostly for digestive and respiratory complaints. High-quality human evidence is very limited,...
Read the full Costus monograph → Herb & supplement monographKudzu
Interacts with 584 drugsKudzu is a fast-growing vine whose root has long been used in traditional Chinese medicine and is now studied mostly for reducing alcohol intake. Early research is promising for cutting back...
Read the full Kudzu monograph → Herb & supplement monographChinese Cucumber
Interacts with 86 drugsChinese cucumber (Trichosanthes kirilowii) is a plant used in traditional Chinese medicine, and a protein from its root called trichosanthin (Compound Q) has been studied as an injectable dr...
Read the full Chinese Cucumber monograph → Herb & supplement monographChrysanthemum
Chrysanthemum flowers are most often used as a soothing tea in traditional Chinese medicine and as a folk remedy for eye irritation, colds, and minor inflammation. Solid human evidence for t...
Read the full Chrysanthemum monograph → Herb & supplement monographTangerine
Interacts with 643 drugsTangerine is a sweet citrus fruit that is a good source of vitamin C and other nutrients, and is widely enjoyed as food. While the peel and essential oil are used in traditional medicine and...
Read the full Tangerine monograph → Herb & supplement monographJapanese Mint
Japanese mint is a menthol-rich plant used mainly for its essential oil in topical rubs, inhalants, and digestive remedies. There is some support for menthol's soothing and cooling effects,...
Read the full Japanese Mint monograph →Sources & How We Checked
Curing Pills's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 84 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Poria Mushroom 3 references
- McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
- Kim H, Park I, Park K, Park S, Kim YI, Park BG. The positive effects of Poria cocos extract on quality of sleep in insomnia rat models. Int J Environ Res Public Health 2022;19(11):6629. PubMed
- Lv Q, Di X, Bian B, Li K, Guo J. Neuroprotective effects of Poria cocos (Agaricomycetes) essential oil on Aß1-40-induced learning and memory deficit in rats. Int J Med Mushrooms 2022;24(10):73-82.
Job's Tears 3 references
- Chiang W, Cheng C, Chiang M, Chung KT. Effects of dehulled adlay on the culture count of some microbiota and their metabolism in the gastrointestinal tract of rats. J Agric Food Chem 2000;48:829-32. PubMed
- Yu YM, Chang WC, Liu CS, Tsai CM. Effect of young barley leaf extract and adlay on plasma lipids and LDL oxidation in hyperlipidemic smokers. Biol Pharm Bull 2004;27:802-5. PubMed
- Yao HT, Lin JH, Liu YT, Li ML, Chiang W. Food-Drug Interaction between the Adlay Bran Oil and Drugs in Rats. Nutrients 2019;11(10):2473. PubMed
Magnolia 9 references
- Kuribara H, Kishi E, Hattori N, et al. The anxiolytic effect of two oriental herbal drugs in Japan attributed to honokiol from magnolia bark. J Pharm Pharmacol 2000;52:1425-9. PubMed
- Tachikawa E, Takahashi M, Kashimoto T. Effects of extract and ingredients isolated from Magnolia obovata thunberg on catecholamine secretion from bovine adrenal chromaffin cells. Biochem Pharmacol 2000;60:433-40. PubMed
- Jung KY, Kim DS, Oh SR, et al. Magnone A and B, novel anti-PAF tetrahydrofuran lignans from the flower buds of Magnolia fargesii. J Nat Prod 1998;61:808-11.
- Garrison R, Chambliss WG. Effect of a proprietary Magnolia and Phellodendron extract on weight management: a pilot, double-blind, placebo-controlled clinical trial. Altern Ther Health Med 2006;12:50-4.
- Teng CM, Chen CC, Ko FN, et al. Two antiplatelet agents from Magnolia officinalis. Thromb Res 1988;50:757-65. PubMed
- Ghys K, De Palma A, Vandevenne A, Werbrouck J, Goossens A. Magnolia officinalis bark extract, a recently identified contact allergen in 'anti-ageing' cosmetics. Contact Dermatitis. 2015 Aug;73(2):130-2.
- Raison-Peyron N, Césaire A, Du-Thanh A, Dereure O. Allergic contact dermatitis caused by Magnolia officinalis bark extract in a facial anti-ageing cream. Contact Dermatitis. 2015 Jun;72(6):416-7.
- Nilausen TD, Johansen JD, Thyssen JP. Allergic contact dermatitis of the face caused by Magnolia officinalis bark extract. Contact Dermatitis. 2016;75(6):385-87.
- Amat-Samaranch V, López-Sánchez C, Tubau C, Puig L, Serra-Baldrich E. Vulvar allergic contact dermatitis caused by Magnolia officinalis bark extract. Contact Dermatitis 2022;87(1):96-97.
Ashitaba 2 references
- Kwon D, Yoon S, Carter O, Bailey GS, Dashwood RH. Antioxidant and antigenotoxic activities of Angelica keiskei, Oenanthe javanica and Brassica oleracea in the Salmonella mutagenicity assay and in HCT116 human colon cancer cells. Biofactors. 2006;26(4):231
- Noh HM, Ahn EM, Yun JM, Cho BL, Paek YJ. Angelica keiskei Koidzumi extracts improve some markers of liver function in habitual alcohol drinkers: a randomized double-blind clinical trial. J Med Food. 2015;18(2):166-72.
Atractylodes 6 references
- Liu Y, Jia Z, Dong L, et al. A randomized pilot study of atractylenolide I on gastric cancer cachexia patients. Evid Based Complement Alternat Med 2008;5:337-44. PubMed
- Chen Y, Yang W, Guo L, Wu X, Zhang T, Liu J, Zhang J. Atractylodes lactone compounds inhibit platelet activation. Platelets. 2017 Mar;28(2):194-202. PubMed
- Jiang H, Shi J, Li Y. Screening for compounds with aromatase inhibiting activities from Atractylodes macrocephala Koidz. Molecules. 2011 Apr 14;16(4):3146-51. PubMed
- Koonrungsesomboon N, Na-Bangchang K, Karbwang J. Therapeutic potential and pharmacological activities of Atractylodes lancea (Thunb.) DC. Asian Pac J Trop Med. 2014 Jun;7(6):421-8. PubMed
- Li L, Tang LY, Man GC, Yeung BH, Lau CB, Leung PC, Wang CC. Potential reproductive toxicity of Largehead Atractylodes Rhizome, the most commonly used Chinese medicine for threatened miscarriage. Hum Reprod. 2011 Dec;26(12):3280-8. PubMed
- Muhamad N, Plengsuriyakarn T, Na-Bangchang K. Atractylodes lancea for cholangiocarcinoma: Modulatory effects on CYP1A2 and CYP3A1 and pharmacokinetics in rats and biodistribution in mice. PLoS One 2022;17(11):e0277614. PubMed
Costus 6 references
- Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
- Marzulli, F. N. and Maibach, H. I. Effects of vehicles and elicitation concentration in contact dermatitis testing. I. Experimental contact sensitization in humans. Contact Dermatitis 1976;2(6):325-329. PubMed
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