Interactions on record — worth a quick check against your medications. Based on 3 of 4 ingredients. Check your meds →
Dietary supplement

D-Mannose with Cranberry and Dandelion Extract Ingredients & Drug Interactions

by Purest Vantage

D-Mannose with Cranberry and Dandelion Extract label
See full label image
Capsule Category: Botanical With Nutrients
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking D-Mannose with Cranberry and Dandelion Extract against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

D-Mannose with Cranberry and Dandelion Extract is a dietary supplement by Purest Vantage with 4 active ingredients. Its ingredients are commonly taken for urinary tract infection prevention, bladder health, antioxidant support.Based on those ingredients, 979 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Cranberry juice powder, Dandelion extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against D-Mannose with Cranberry and Dandelion Extract by Purest Vantage

Ask about any prescription or over-the-counter medication and we check it for interactions with D-Mannose with Cranberry and Dandelion Extract by Purest Vantage — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of D-Mannose with Cranberry and Dandelion Extract by Purest Vantage

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 23, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 3 of its 3 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains 3 active ingredients. D-Mannose is a simple sugar your body normally produces; cranberry juice powder is made from the whole fruit; and dandelion extract comes from the plant root.

The capsule itself is made of methylcellulose, an inactive ingredient that holds everything together. D-Mannose is used mainly for a rare genetic condition.

Cranberry is taken by mouth to try to prevent urinary tract infections, though it may not work for that purpose. Dandelion has been studied for various uses, but the evidence for any of them isn't reliable enough to establish whether it actually works.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: urinary tract health and infection prevention.
  • We looked for evidence on: Urinary tract infections (UTIs), Overactive bladder, Radiation-induced cystitis, Catheter-related infections, Urinary odor, Cystitis — and 3 related terms.
  • The strongest evidence on file: Cranberry is rated "Possibly Effective" for Urinary tract infections (UTIs) (Natural Medicines).
  • Also on file: D-mannose is rated "Possibly Ineffective" for Urinary tract infections (UTIs).
  • Also on file: Dandelion is rated "Insufficient Reliable Evidence To Rate" for Urinary tract infections (UTIs).

For urinary tract infections (UTIs), cranberry is rated Possibly Effective—meaning there's some evidence it may help, but it's not certain. D-Mannose, however, is rated Possibly Ineffective for UTIs, so it's unlikely to prevent or treat them despite what some marketing suggests.

D-Mannose is Likely Effective for carbohydrate-deficient glycoprotein syndrome type 1b, a rare inherited metabolic disorder, but that's a specialized medical use. Dandelion's effectiveness for any condition—including joint pain, tonsillitis, or postoperative swelling and pain—is rated Insufficient Reliable Evidence To Rate, meaning we don't have solid data showing whether it works.

Cranberry also has insufficient evidence for cognitive decline, benign prostate enlargement, cancer, fatty liver disease, and chronic fatigue syndrome.

The evidence, ingredient by ingredient Cranberry D-mannose Dandelion

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

All three ingredients are generally well tolerated in food amounts. Cranberry is rated Likely Safe in pregnancy and lactation.

However, the safety data for concentrated supplement doses—especially long-term use—is limited for all three, so check with your provider before taking this product. Common side effects from cranberry are diarrhea and stomach upset; D-mannose may cause bloating, diarrhea, and nausea; dandelion can bring on diarrhea, heartburn, and stomach discomfort.

Dandelion can also cause skin rashes if it touches your skin, and allergic reactions (even rare anaphylaxis) have been reported in people sensitive to plants in the ragweed family. Pregnancy and lactation safety data for D-mannose and dandelion are not on file, so talk with your doctor or pharmacist for personalized advice if you're pregnant or breastfeeding.

Side effects, ingredient by ingredient Cranberry D-mannose Dandelion

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 3 matched ingredients can interact with medications — Dandelion, Cranberry.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications; lithium.
  • For scale: 980 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, have your doctor or pharmacist check for interactions if you take blood thinners (anticoagulants or antiplatelet drugs)—both cranberry and dandelion may increase bleeding risk. Next, watch for interactions with cholesterol medications, calcium channel blockers, blood sugar drugs, potassium-sparing water pills, fluoroquinolone antibiotics (like ciprofloxacin), or lithium.

Cranberry and dandelion together affect how your liver handles many common drugs, so even if you don't see your specific medication listed, ask your pharmacist to search it against both ingredients.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This product mixes an ingredient with no interactions (D-mannose) with two that interact with many common medications—especially blood thinners, cholesterol drugs, water pills, antibiotics, and diabetes medications. If you take any prescription drugs, blood pressure pills, or blood thinners, check your exact medications with the tool on this page and confirm with your doctor or pharmacist before starting.

Even if your interactions look minor, concentrated herbal supplements haven't been studied as thoroughly as prescription medications, so it's worth a quick conversation.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Oct 24, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about D-Mannose with Cranberry and Dandelion Extract, straight from the product label.

Brand Purest Vantage
Barcode (UPC) X001JIT2W5
Net contents 120 Vegetarian Capsule(s)
Market status On market
Date entered into DSLD Oct 24, 2022
DSLD ID 276276
Product type Botanical With Nutrients
Supplement form Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for D-Mannose with Cranberry and Dandelion Extract by Purest Vantage, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
120
UPC/BARCODE
X001JIT2W5
IngredientAmount% DV
Total Carbohydrates1 Gram(s)1%
Sugar1 Gram(s)--
Cranberry juice powder100 mg--
D-Mannose600 mg--
Dandelion extract50 mg--

Other ingredients: Methylcellulose Capsule

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Precautions

Caution: Pregnant or nursing mothers, children under the age of 18, and individuals with a known medical condition should consult a healthcare professional before using this or any dietary supplement.

Caution: Pregnant or nursing mothers, children under the age of 18, and individuals with a known medical condition should consult a healthcare professional before using this or any dietary supplement.

Allergen Warning: This product contains Dandelion Extract. Avoid use if you are allergic to ragweed or daisy-like flowers.

Keep out of reach of children.

Do not use if safety seal is damaged or missing.

Formulation

Does not contain: GMOs, fillers, binders, preservatives, stearates, artificial ingredients, silicone dioxide, or titanium dioxide.

Made in USA with global ingredients

Urinary tract formula

Storage

Store in a cool, dry place.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Seals/Symbols

GMP Good Manufacturing Practice

Formula

D-Mannose with cranberry and dandelion extract Potent 750 mg formula per capsule

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Suggested Use: Take 1 capsule twice daily, or as recommended by your healthcare practitioner.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

D-Mannose with Cranberry and Dandelion Extract by Purest Vantage label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

D-Mannose with Cranberry and Dandelion Extract label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in D-Mannose with Cranberry and Dandelion Extract by Purest Vantage

These are the 4 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container120 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Sugar

1 Gram(s) per serving

Cranberry juice powder

Interacts with
712 drugs
100 mg per serving

Cranberry is best known for helping to prevent repeated urinary tract infections (UTIs) in some people, and the evidence here is moderate but mixed. I...

Cranberry juice powder monograph & interactions

D-Mannose

No known
interactions
600 mg per serving

D-mannose is a natural sugar most often used to help prevent urinary tract infections, especially those caused by E. coli. Early research is promising...

D-Mannose monograph & interactions

Dandelion extract

Interacts with
457 drugs
50 mg per serving

Dandelion is a common plant used in food and traditional medicine, often promoted as a natural 'water pill' and digestive aid. Human evidence for thes...

Dandelion extract monograph & interactions

Other (inactive) ingredients: Methylcellulose Capsule. These complete the product’s ingredient list but are not active constituents.

Interaction report

D-Mannose with Cranberry and Dandelion Extract by Purest Vantage Drug Interactions

Want to check YOUR meds against D-Mannose with Cranberry and Dandelion Extract?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
979Drugs
942 Moderate 37 Minor

Ingredients driving the most interactions

Cranberry juice powder 712
Dandelion extract 457

Individual Drug Interactions

The ingredients in D-Mannose with Cranberry and Dandelion Extract interact with 979 drugs. Click any drug to see the details.

2 of the 4 ingredients in D-Mannose with Cranberry and Dandelion Extract interact with drugs. Each result below shows which ingredient is responsible. Cranberry juice powder Dandelion extract

Each ingredient & the kinds of drugs it affects

For each ingredient in D-Mannose with Cranberry and Dandelion Extract with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Cranberry juice powder6 drug types · 712 drugs

Atorvastatin (Lipitor)

Theoretically, cranberry might increase levels and adverse effects of atorvastatin.
In one case report, a patient taking atorvastatin experienced upper back pain, rhabdomyolysis, and abnormal liver function after drinking cranberry juice 16 ounces daily for 2 weeks. Theoretically, this may have been caused by inhibition of cytochrome P450 3A4 (CYP3A4) enzymes by cranberry juice, as atorvastatin is a CYP3A4 substrate. Creatinine kinase and liver enzymes normalized within 2 weeks of stopping cranberry juice. Patients taking atorvastatin should avoid large quantities of cranberry juice.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, cranberry might increase the levels and adverse effects of CYP3A4 substrates.
A case of upper back pain, rhabdomyolysis, and abnormal liver function has been reported for a patient taking atorvastatin, a CYP3A4 substrate, in combination with cranberry juice 16 ounces daily for 2 weeks. Creatinine kinase and liver enzymes normalized within 2 weeks of stopping cranberry juice. Also, animal research suggests that cranberry juice, administered intraduodenally 30 minutes prior to nifedipine, a CYP3A4 substrate, inhibits nifedipine metabolism and increases the area under the concentration-time curve by 1.6-fold compared to control.

Likelihood Possible Evidence D
Nifedipine (Procardia)

Theoretically, cranberry might increase the levels and adverse effects of nifedipine.
Animal research suggests that cranberry juice, administered intraduodenally 30 minutes prior to nifedipine treatment, inhibits nifedipine metabolism and increases the area under the concentration-time curve by 1.6-fold compared to control. This interaction has not been reported in humans.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Theoretically, cranberry might increase the levels and adverse effects of warfarin. However, research is conflicting.
There is contradictory evidence about the effect of cranberry juice on warfarin. Case reports have linked cranberry juice consumption to increases in the international normalized ratio (INR) in patients taking warfarin, resulting in severe spontaneous bleeding and excessive postoperative bleeding. Daily consumption of cranberry sauce for one week has also been linked to an increase in INR in one case report. In a small study in healthy young males, taking a high dose of 3 grams of cranberry juice concentrate capsules, equivalent to 57 grams of fruit daily, for 2 weeks produced a 30% increase in the area under the INR-time curve after a single 25-mg dose of warfarin. However, 3 very small clinical studies in patients stabilized on warfarin reported that cranberry juice 250 mL once or twice daily for 7 days (27% cranberry juice or pure cranberry juice) or 240 mL once daily for 14 days does not significantly increase INR or affect plasma warfarin levels. The reasons for these discrepant findings are unclear. It is possible that the form and dose of cranberry may play a role, as cranberry extracts and juices contain different constituents. Additionally, an in vitro study evaluating 5 different cranberry juices found varying effects, with only a cranberry concentrate, and not diluted cranberry juices, inhibiting CYP2C9. However, this concentrate did not inhibit CYP2C9 activity in humans.

Likelihood Possible Evidence B
Cytochrome P450 2C9 (Cyp2C9) Substrates

Theoretically, cranberry might increase the levels and adverse effects of CYP2C9 substrates. However, research is conflicting.
There is contradictory evidence about the effect of cranberry on CYP2C9 enzymes. In vitro evidence suggests that flavonoids in cranberry inhibit CYP2C9 enzymes. However, clinical research shows that cranberry juice does not significantly affect the levels, metabolism, or elimination of the CYP2C9 substrates flurbiprofen or diclofenac. Also, in patients stabilized on warfarin, drinking cranberry juice 250 mL daily for 7 days does not significantly increase the anticoagulant activity of warfarin, a CYP2C9 substrate. Additional pharmacokinetic research shows that cranberry juice does not increase peak plasma concentrations or area under the concentration-time curve of warfarin.

Likelihood Unlikely Evidence B
Diclofenac (Voltaren, Others)

Theoretically, cranberry might modestly increase the levels and adverse effects of diclofenac.
In vitro evidence suggests that cranberry juice inhibits diclofenac metabolism by human liver microsomes. However, drinking cranberry juice does not seem to affect diclofenac metabolism in humans.

Likelihood Unlikely Evidence B
Cranberry juice powder full monograph & interactions

Dandelion extract7 drug types · 457 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, taking dandelion root along with anticoagulant or antiplatelet drugs might increase the risk of bruising and bleeding.
In vitro research suggests that dandelion root inhibits platelet aggregation.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, dandelion might increase the risk for hypoglycemia when used with antidiabetes drugs.
Laboratory research suggests that dandelion extract may have moderate alpha-glucosidase inhibitor activity and might also increase insulin secretion. Also, in a case report, a 58-year-old woman with type 2 diabetes who was being treated with insulin developed hypoglycemia 2 weeks after beginning to eat salads containing dandelion.

Likelihood Possible Evidence D
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, dandelion might increase levels of drugs metabolized by CYP1A2.
Laboratory research suggests that dandelion might inhibit CYP1A2. So far, this interaction has not been reported in humans. However, until more is known, watch for an increase in the levels of drugs metabolized by CYP1A2 in patients taking dandelion.

Likelihood Possible Evidence D
Glucuronidated Drugs

Theoretically, dandelion might increase the clearance of drugs that are UDP-glucuronosyltransferase substrates.
There is some preliminary evidence that dandelion might induce UDP-glucuronosyltransferase, a phase II enzyme.

Likelihood Possible Evidence D
Lithium

Theoretically, through diuretic effects, dandelion might reduce excretion and increase levels of lithium.
Animal research suggests that dandelion has diuretic properties. As diuretics can increase serum lithium levels, the dose of lithium might need to be decreased when taken with dandelion.

Likelihood Probable Evidence D
Potassium-Sparing Diuretics

Theoretically, dandelion might increase the risk of hyperkalemia when taken with potassium-sparing diuretics.
Dandelion contains significant amounts of potassium.

Likelihood Possible Evidence D
Quinolone Antibiotics

Theoretically, dandelion might lower fluoroquinolone levels.
Animal research shows that dandelion reduces absorption of ciprofloxacin and can lower levels by 73%. However, this effect has not been reported in humans.

Likelihood Possible Evidence D
Dandelion extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for D-Mannose with Cranberry and Dandelion Extract, from the product label.

Purest Vantage

See all Purest Vantage products
Name
Purest Vantage
Street Address
390 North Orange Avenue, Suite 2300-C
City
Orlando
State
FL
ZipCode
32801
Web Address
www.purestvantage.com
Pharmacist Counseling Corner

D-Mannose with Cranberry and Dandelion Extract by Purest Vantage: Common Questions

Does D-Mannose with Cranberry and Dandelion Extract by Purest Vantage interact with any medications?
Yes. Based on its ingredients, D-Mannose with Cranberry and Dandelion Extract has a known interaction with 979 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
D-Mannose with Cranberry and Dandelion Extract contains 4 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm on a blood thinner like warfarin?
No—not without checking first with your doctor or pharmacist. Cranberry may unpredictably raise warfarin levels, and dandelion root may increase bleeding and bruising risk. Both ingredients interact with blood thinners, so you need personalized advice before combining them.
Does D-mannose actually prevent urinary tract infections?
The evidence says it probably doesn't work for that—it's rated Possibly Ineffective for UTIs. Cranberry in this product is rated Possibly Effective for UTIs, meaning there's some evidence but it's not certain. Talk to your doctor about proven options if you get UTIs often.
What are the most common side effects?
Diarrhea, nausea, bloating, and stomach upset are the main ones reported across all three ingredients. Very high doses of cranberry (like 3–4 liters of juice daily) can cause stronger gastrointestinal problems, especially in children. Most people tolerate normal doses, but if you have a sensitive stomach, start low.
Is it safe to take while breastfeeding?
Cranberry is rated Likely Safe while breastfeeding. However, we don't have enough safety data on D-mannose or dandelion while breastfeeding, so talk with your doctor or pharmacist for personalized advice before taking this product.
Can I take this long-term?
Long-term safety data for concentrated supplement doses of all three ingredients are limited, so it's best to check with your provider first rather than assume it's fine indefinitely. Food amounts of cranberry and dandelion are likely okay, but supplement strength is less studied.
What if I'm allergic to ragweed or daisies?
Dandelion can trigger allergic reactions in people sensitive to plants in the ragweed family (which includes daisies, chrysanthemums, and marigolds). If you have those allergies, avoid this product or talk with your doctor first—serious reactions like anaphylaxis are rare but possible.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if D-Mannose with Cranberry and Dandelion Extract is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

D-Mannose with Cranberry and Dandelion Extract label
Go deeper

The Full Monographs Behind D-Mannose with Cranberry and Dandelion Extract’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Cranberry

Interacts with 712 drugs

Cranberry is best known for helping to prevent repeated urinary tract infections (UTIs) in some people, and the evidence here is moderate but mixed. It is not a reliable treatment for an act...

Read the full Cranberry monograph → Herb & supplement monograph

D-mannose

D-mannose is a natural sugar most often used to help prevent urinary tract infections, especially those caused by E. coli. Early research is promising for prevention, but the evidence is sti...

Read the full D-mannose monograph → Herb & supplement monograph

Dandelion

Interacts with 457 drugs

Dandelion is a common plant used in food and traditional medicine, often promoted as a natural 'water pill' and digestive aid. Human evidence for these uses is very limited, so its benefits...

Read the full Dandelion monograph →
Sources

Sources & How We Checked

D-Mannose with Cranberry and Dandelion Extract's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 66 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Cranberry 33 references
  1. Anon. Possible interaction between warfarin and cranberry juice. Current Problems in Pharmacovigilance 2003;29:8. PubMed
  2. Greenblatt DJ, von Moltke LL, Perloff ES, et al. Interaction of flurbiprofen with cranberry juice, grape juice, tea, and fluconazole: in vitro and clinical studies. Clin Pharmacol Ther 2006;79:125-33. PubMed
  3. Hodek P, Trefil P, Stiborova M. Flavonoids-potent and versatile biologically active compounds interacting with cytochromes P450. Chem Biol Interact 2002;139:1-21.. PubMed
  4. Grant P. Warfarin and cranberry juice: An interaction? J Heart Valve Dis 2004;13:25-6.
  5. Suvarna R, Pirmohamed M, Henderson L. Possible interaction between warfarin and cranberry juice. BMJ 2003;327:1454. PubMed
  6. Li Z, Seeram NP, Carpenter CL, et al. Cranberry does not affect prothrombin time in male subjects on warfarin. J Am Diet Assoc 2006;106:2057-61. PubMed
  7. Lilja JJ, Backman JT, Neuvonen PJ. Effects of daily ingestion of cranberry juice on the pharmacokinetics of warfarin, tizanidine, and midazolam - probes of CYP2C9, CYP1A2 and CYP3A4. Clin Pharmacol The 2007:81:833-9. PubMed
  8. Wing DA, Rumney PJ, Preslicka CW, Chung JH. Daily cranberry juice for the prevention of asymptomatic bacteriuria in pregnancy: a randomized, controlled pilot study. J Urol 2008;180:1367-72. PubMed
  9. Mohammed Abdul MI, Jiang X, Williams KM, et al. Pharmacodynamic interaction of warfarin with cranberry but not with garlic in healthy subjects. Br J Pharmacol 2008;154:1691-700. PubMed
  10. McMurdo MET, Argo I, Phillips G, et al. Cranberry or trimethoprim for the prevention of recurrently urinary tract infections? A randomized controlled trial in older women. J Antimicrob Chemother 2009;63:389-95.
  11. Mergenhagen KA, Sherman O. Elevated International Normalized Ratio after concurrent ingestion of cranberry sauce and warfarin. Am J Health-Syst Pharm 2008;65:2113-6. PubMed
  12. Ansell J, McDonough M, Zhao Y, et al. The absence of an interaction between warfarin and cranberry juice: a randomized, double-blind trial. J Clin Pharmacol 2009;49:824-30. PubMed
  13. Haber SL, Cauthon KA, Raney EC. Cranberry and warfarin interaction: a case report and review of the literature. Consult Pharm 2012;27:58-65. PubMed
  14. Hamann GL, Campbell JD, George CM. Warfarin-cranberry juice interaction. Ann Pharmacother 2011;45:e17. PubMed
  15. Roberts D, Flanagan P. Case report: Cranberry juice and warfarin. Home Healthc Nurse 2011;29:92-7.
  16. Garcia-Calatayud, S., Larreina Cordoba, J. J., and Lozano De La Torre MJ. [Severe cranberry juice poisoning]. An.Esp.Pediatr. 2002;56(1):72-73.
  17. Patel, D. A., Gillespie, B., Sobel, J. D., Leaman, D., Nyirjesy, P., Weitz, M. V., and Foxman, B. Risk factors for recurrent vulvovaginal candidiasis in women receiving maintenance antifungal therapy: results of a prospective cohort study. Am J Obstet.Gy PubMed
  18. Isele, H. [Fatal bleeding under warfarin plus cranberry juice. Is it due to salicylic acid?]. MMW.Fortschr.Med 3-11-2004;146(11):13.
  19. Linsenmeyer, T. A., Harrison, B., Oakley, A., Kirshblum, S., Stock, J. A., and Millis, S. R. Evaluation of cranberry supplement for reduction of urinary tract infections in individuals with neurogenic bladders secondary to spinal cord injury. A prospecti
  20. McMurdo, M. E., Bissett, L. Y., Price, R. J., Phillips, G., and Crombie, I. K. Does ingestion of cranberry juice reduce symptomatic urinary tract infections in older people in hospital? A double-blind, placebo-controlled trial. Age Ageing 2005;34(3):256- PubMed
  21. Sylvan, L. and Justice, N. P. Possible interaction between warfarin and cranberry juice. Am Fam.Physician 9-15-2005;72(6):1000.
  22. Niklasson, A. and Andren, L. [Interaction between Waran and cranberry juice]. Lakartidningen 3-15-2006;103(11):853-854.
  23. Rindone, J. P. and Murphy, T. W. Warfarin-cranberry juice interaction resulting in profound hypoprothrombinemia and bleeding. Am J Ther 2006;13(3):283-284. PubMed
  24. Uesawa, Y. and Mohri, K. Effects of cranberry juice on nifedipine pharmacokinetics in rats. J Pharm Pharmacol 2006;58(8):1067-1072. PubMed
  25. Valentova, K., Stejskal, D., Bednar, P., Vostalova, J., Cihalik, C., Vecerova, R., Koukalova, D., Kolar, M., Reichenbach, R., Sknouril, L., Ulrichova, J., and Simanek, V. Biosafety, antioxidant status, and metabolites in urine after consumption of dried
  26. Royer, D. J., George, J. N., and Terrell, D. R. Thrombocytopenia as an adverse effect of complementary and alternative medicines, herbal remedies, nutritional supplements, foods, and beverages. Eur J Haematol 2010;84(5):421-429. PubMed
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

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