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Dietary supplement

D-Ribose with BioEnergy Ribose 850 mg Ingredients & Drug Interactions

by Doctor's Best

D-Ribose with BioEnergy Ribose 850 mg label
See full label image
Capsule Category: Fiber And Other Nutrients
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking D-Ribose with BioEnergy Ribose 850 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

D-Ribose with BioEnergy Ribose 850 mg is a dietary supplement by Doctor's Best with 1 active ingredient. Its ingredients are commonly taken for energy and fatigue, athletic performance and recovery, fibromyalgia symptoms.Based on those ingredients, 86 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Bioenergy Ribose. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against D-Ribose with BioEnergy Ribose 850 mg by Doctor's Best

Ask about any prescription or over-the-counter medication and we check it for interactions with D-Ribose with BioEnergy Ribose 850 mg by Doctor's Best — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of D-Ribose with BioEnergy Ribose 850 mg by Doctor's Best

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 23, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: Bioenergy Ribose, a five-carbon sugar your body uses to make energy in muscle and heart cells. The capsule also holds three inactive ingredients — hypromellose (a capsule binder), magnesium stearate (a lubricant), and silicon dioxide (an anti-caking agent).

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Ribose's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: enhance ATP energy production.
  • We looked for evidence on: Athletic performance, Chronic fatigue syndrome (CFS), Fibromyalgia, Congestive heart failure (CHF), Coronary artery bypass graft (CABG) surgery, Coronary heart disease (CHD) — and 4 related terms.
  • The closest evidence on file: Ribose is rated "Possibly Ineffective" for Athletic performance (Natural Medicines).
  • Also on file: Ribose is rated "Possibly Ineffective" for McArdle disease.
  • Also on file: Ribose is rated "Insufficient Reliable Evidence To Rate" for Coronary heart disease (CHD), Chronic fatigue syndrome (CFS), Congestive heart failure (CHF), Fibromyalgia, and more.

The evidence for ribose is mixed and often falls short. For athletic performance and McArdle disease (a rare muscle disorder), the data suggests it's probably not effective.

For restless legs syndrome, muscle soreness, heart failure, and recovery after bypass surgery, we don't have enough reliable evidence to say whether it works or not.

The evidence, ingredient by ingredient Ribose

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Ribose is generally well tolerated over about a month, but long-term safety hasn't been well studied. The most common side effects are diarrhea, stomach discomfort, headache, nausea, and — because it lowers blood sugar — low blood sugar itself.

A small number of people reported anxiety or anxious feelings, lightheadedness, and increased appetite; in one case, lowering the dose resolved the anxiety. You should not take ribose during pregnancy or while breastfeeding — there isn't enough safety information to know if it's safe for your baby.

Talk with your doctor or pharmacist before taking it if you're pregnant, planning to become pregnant, or nursing.

Side effects, ingredient by ingredient Ribose

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Ribose.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 86 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check your antidiabetes drugs and insulin before taking this product — both carry a Moderate risk of low blood sugar when combined with ribose. If you take either of these, your healthcare provider should know you're adding this supplement and may need to monitor your blood sugar more closely.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

D-Ribose may be worth considering if you're interested in energy support and have talked with your doctor about the limited evidence for its uses. Be cautious if you take any diabetes medication or insulin — this product can lower blood sugar, and you'll want to monitor levels closely and adjust doses if needed.

Stop by and talk it over with your doctor or pharmacist before you start, especially if you're on blood-sugar-lowering drugs.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Feb 22, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about D-Ribose with BioEnergy Ribose 850 mg, straight from the product label.

Brand Doctor's Best
Barcode (UPC) 753950001930
Net contents 120 Veggie Cap(s)
Market status On market
Date entered into DSLD Feb 22, 2024
DSLD ID 302653
Product type Fiber And Other Nutrients
Supplement form Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for D-Ribose with BioEnergy Ribose 850 mg by Doctor's Best, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
5 Veggie Capsule(s)
Maximum serving Sizes:
5 Veggie Capsule(s)
Servings per container
24
UPC/BARCODE
753950001930
IngredientAmount% DV
Calories15 Calorie(s)--
Total Sugars4 Gram(s)--
Total Carbohydrates4 Gram(s)2%
Bioenergy Ribose4250 mg--

Other ingredients: Hypromellose, Magnesium Stearate, Silicon Dioxide

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Doctor's Best D-Ribose is a unique 5-carbon carbohydrate that is a fundamental building block of ATP (adenosine triphosphate), the source for all cellular energy. Ribose is the starting point and rate limiting compound in the synthesis of these fundamental cellular compounds. The availability of ribose determines the rate at which they can be made by our cells and tissues. Studies have shown that ribose supplementation can enhance cardiac energy levels and support cardiovascular metabolism. Further studies suggest that ribose plays a role in supporting muscle energy recovery after exercise. Exercise increases free radical production in muscle tissue. Ribose may strengthen and support the body's crucial antioxidant defenses.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Brand IP Statement(s)

Science-Based Nutrition

Use of BioEnergy Ribose is licensed by BioEnergy Life Science, Inc. under U.S. and foreign patents issued and pending.

FDA Statement of Identity

Dietary Supplement

Formulation

Helps enhance ATP energy production

Vegan

Non-GMO/Gluten free/Soy free/ Vegan

Non-GMO/Gluten free/Soy free/ Vegan

Helps support energy production in heart and muscle Helps promote muscle recovery following exercise Helps decrease free radical production during excercise

Suggested/Recommended/Usage/Directions

Suggested adult use: Take 5 capsules twice daily, preferably with food, or as recommended by a nutritionally informed physician.

Precautions

Warning: Diabetics, pregnant or lactating women, and those with chronic gout should consult their physician before using this product.

Storage

Store in a cool dry place.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

D-Ribose with BioEnergy Ribose 850 mg by Doctor's Best label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

D-Ribose with BioEnergy Ribose 850 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in D-Ribose with BioEnergy Ribose 850 mg by Doctor's Best

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size5 Veggie Capsule(s) Dosage formCapsule Servings per container24 Amounts shown are per serving.

Bioenergy Ribose

Interacts with
86 drugs
4250 mg per serving Form: D-Ribose

Ribose (D-ribose) is a simple sugar your body makes naturally and uses to build energy molecules like ATP. Some people take it for fatigue, fibromyalg...

Bioenergy Ribose monograph & interactions

Other (inactive) ingredients: Hypromellose, Magnesium Stearate, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.

Interaction report

D-Ribose with BioEnergy Ribose 850 mg by Doctor's Best Drug Interactions

Want to check YOUR meds against D-Ribose with BioEnergy Ribose 850 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
86Drugs
86 Moderate

Ingredients driving the most interactions

Bioenergy Ribose 86

Individual Drug Interactions

The ingredients in D-Ribose with BioEnergy Ribose 850 mg interact with 86 drugs. Click any drug to see the details.

1 of the 1 ingredient in D-Ribose with BioEnergy Ribose 850 mg interact with drugs. Each result below shows which ingredient is responsible. Bioenergy Ribose

Each ingredient & the kinds of drugs it affects

For each ingredient in D-Ribose with BioEnergy Ribose 850 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Bioenergy Ribose2 drug types · 86 drugs

Antidiabetes Drugs

Theoretically, taking ribose in combination with antidiabetes drugs might increase the risk of hypoglycemia.
In clinical research, ribose decreases serum glucose levels in a dose-dependent manner.

Likelihood Probable Evidence B
Insulin

Theoretically, taking ribose with insulin could increase the hypoglycemic effect of insulin.
In clinical pharmacokinetic studies, oral administration of ribose modestly increased serum insulin levels.

Likelihood Possible Evidence B
Bioenergy Ribose full monograph & interactions
The maker

Brand information

Manufacturer and brand details for D-Ribose with BioEnergy Ribose 850 mg, from the product label.

Doctor's Best

See all Doctor's Best products
Name
Doctor's Best, Inc.
City
Tustin
State
California
ZipCode
92780
Phone Number
(800) 777-2474
Web Address
www.drbvitamins.com
Pharmacist Counseling Corner

D-Ribose with BioEnergy Ribose 850 mg by Doctor's Best: Common Questions

Does D-Ribose with BioEnergy Ribose 850 mg by Doctor's Best interact with any medications?
Yes. Based on its ingredients, D-Ribose with BioEnergy Ribose 850 mg has a known interaction with 86 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
D-Ribose with BioEnergy Ribose 850 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take D-Ribose if I have diabetes?
It's possible, but you'll need to be careful. Ribose lowers blood sugar, so if you take antidiabetes drugs or insulin, there's a Moderate risk of your blood sugar dropping too far. Talk with your doctor or pharmacist first — they may need to watch your levels more closely or adjust your medication doses.
Will D-Ribose help my athletic performance?
The evidence suggests it probably won't. Ribose is rated as possibly ineffective for athletic performance based on current research.
What are the most common side effects?
The most common ones are diarrhea, stomach discomfort, headache, nausea, and low blood sugar. A small number of people also reported anxiety, lightheadedness, or increased appetite. Lowering the dose resolved these issues in some cases.
Is it safe to take D-Ribose while pregnant or breastfeeding?
No — there isn't enough safety information, so it's best avoided during pregnancy and while breastfeeding. Talk with your doctor or pharmacist if you're pregnant, planning to become pregnant, or nursing.
How long can I safely take D-Ribose?
Ribose is generally well tolerated for about a month, but long-term safety hasn't been well studied. If you're thinking of taking it longer than that, check with your doctor or pharmacist.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if D-Ribose with BioEnergy Ribose 850 mg is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

D-Ribose with BioEnergy Ribose 850 mg label
Go deeper

The Full Monographs Behind D-Ribose with BioEnergy Ribose 850 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Ribose

Interacts with 86 drugs

Ribose (D-ribose) is a simple sugar your body makes naturally and uses to build energy molecules like ATP. Some people take it for fatigue, fibromyalgia, exercise recovery, or heart conditio...

Read the full Ribose monograph →
Sources

Sources & How We Checked

D-Ribose with BioEnergy Ribose 850 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 8 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Ribose 8 references
  1. Segal S, Foley J. The metabolism of D-ribose in man. J Clin Invest 1958;37:719-35. PubMed
  2. Perlmutter NS, Wilson RA, Angello DA, et al. Ribose facilitates thallium-201 redistribution in patients with coronary artery disease. J Nucl Med 1991;32:193-200.
  3. Hegewald MG, Palac RT, Angello DA, et al. Ribose infusion accelerates thallium redistribution with early imaging compared with late 24-hour imaging without ribose. J Am Coll Cardiol 1991;18:1671-81. PubMed
  4. Pliml W, von Arnim T, Stalein A, et al. Effects of ribose on excercise-induced ischaemia in stable coronary artery disease. Lancet 1992;340:507-10.
  5. Burke ER. D-Ribose What You Need To Know. Garden City Park, NY: Avery Publishing Group 1999;1-43.
  6. Gross M, Reiter S, Zollner N. Metabolism of D-ribose administered continuously to healthy persons and to patients with myoadenylate deaminase deficiency. Klin Wochenschr 1989;67:1205-13. PubMed
  7. Teitelbaum JE, Johnson C, St Cyr J. The use of D-ribose in chronic fatigue syndrome and fibromyalgia: a pilot study. J Altern Complement Med 2006;12:857-62. PubMed
  8. Thompson J, Neutel J, Homer K, Tempero K, Shah A, Khankari R. Evaluation of D-ribose pharmacokinetics, dose proportionality, food effect, and pharmacodynamics after oral solution administration in healthy male and female subjects. J Clin Pharmacol 2014;54 PubMed

See these in context on the Ribose monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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