Deflect B Ingredients & Drug Interactions
by D'Adamo Personalized Nutrition
What is this page for?
First and foremost: checking Deflect B against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Deflect B is a dietary supplement by D'Adamo Personalized Nutrition with 6 active ingredients. Its ingredients are commonly taken for thinning mucus in lung conditions, acetaminophen (tylenol) overdose treatment, antioxidant and glutathione support.Based on those ingredients, 2,213 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Gum Tragacanth, Flaxseed Meal, N-Acetyl Cysteine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Deflect B by D'Adamo Personalized Nutrition
Ask about any prescription or over-the-counter medication and we check it for interactions with Deflect B by D'Adamo Personalized Nutrition — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Deflect B by D'Adamo Personalized Nutrition
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
Deflect B contains six active ingredients. N-acetyl cysteine is a compound that supports the body's antioxidant defense and is used clinically for acetaminophen overdose, blocked airways (atelectasis), and lung congestion.
Gum tragacanth is a thickening fiber. Larch arabinogalactan is a prebiotic fiber from larch wood.
N-acetyl-D-glucosamine (a form of glucosamine) is a building block for joint cartilage and connective tissue. Pectin is a soluble fiber from fruit.
Flaxseed meal is ground flaxseed, a source of fiber and lignans. The product also contains inactive ingredients: cellulose, rice extract, and rice concentrate.
Does it work?
Couldn't assess
The evidence for this product's active ingredients varies widely. N-acetyl cysteine is effective for acetaminophen poisoning, blocked airways, and tracheostomy care, and possibly effective for bronchitis.
Glucosamine is likely effective for osteoarthritis. Pectin and flaxseed are both possibly effective for high cholesterol; flaxseed is also possibly effective for diabetes, breast pain (mastalgia), high blood pressure, and constipation.
For the other uses studied — larch arabinogalactan and gum tragacanth for colds and cholesterol, glucosamine for aging skin, back pain, and liver disease, and pectin for prediabetes — the evidence is insufficient to rate them.
How safe is it?
Well-documented data
N-acetyl cysteine is generally well tolerated at typical doses; the most common side effects from oral use are diarrhea, dry mouth, indigestion, heartburn, loss of appetite, nausea, and vomiting. Joint pain was reported in more than 15% of people in one trial.
Glucosamine is generally well tolerated orally; common side effects include bloating, constipation, cramps, diarrhea, heartburn, and nausea. Rare severe allergic reactions including anaphylaxis have been reported.
Flaxseed typically causes bloating, diarrhea, and other gastrointestinal complaints, especially at higher doses. Pectin is well tolerated; common side effects are diarrhea, gas, loose stools, and mild cramps.
Larch arabinogalactan can cause bloating and flatulence. There is not enough pregnancy and lactation safety data on file for N-acetyl cysteine, glucosamine, larch arabinogalactan, or flaxseed, so discuss with your doctor if you are pregnant or breastfeeding.
Gum tragacanth should be avoided in medicinal amounts during pregnancy and breastfeeding. Pectin is likely safe in food amounts and possibly safe in pregnancy at normal supplement doses, but concentrated supplements have not been well studied.
Meds to double-check
Major interaction found
Before taking Deflect B, double-check if you use nitroglycerin (Major severity), warfarin or other blood thinners, blood pressure medications, antidiabetes drugs, antibiotics, cholesterol-lowering drugs like lovastatin or digoxin, chemotherapy agents, estrogen-based medications, antimalarial drugs like chloroquine, or immunosuppressants. If you take any of these, run them through the medication checker below.
The bottom line
Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Major medication interactions have been identified, and safety information is well characterized.
If you take a heart medication, blood thinner, blood pressure drug, antidiabetes medication, antibiotic, or chemotherapy, check your exact prescriptions with the tool on this page before starting Deflect B. This product is not appropriate for everyone — especially if you're pregnant, breastfeeding, or managing a serious chronic condition.
Talk to your pharmacist about whether it's right for you.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 6 of 6 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jun 22, 2023.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Deflect B, straight from the product label.
| Brand | D'Adamo Personalized Nutrition |
|---|---|
| Net contents | 120 Vegetarian Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Jun 22, 2023 |
| DSLD ID | 287133 |
| Product type | Other Combinations |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Deflect B by D'Adamo Personalized Nutrition, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| N-Acetyl Cysteine | 200 mg | -- |
| Gum Tragacanth | 100 mg | -- |
| Larch Arabinogalactan | 500 mg | -- |
| N-Acetyl-D-Glucosamine | 200 mg | -- |
| Pectin | 400 mg | -- |
| Flaxseed Meal | 100 mg | -- |
Other ingredients: Cellulose, Rice extract, Rice Concentrate
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula
Right for your type B Lectin blocking formula designed for type B individuals
FDA Statement of Identity
Dietary Supplement
Formulation
Stearate free encapsulation
Dr. Peter D'Adamo has identified dietary lectins (proteins found in many common foods) as an important influence of the body's immune system and metabolism. As a result of this research, he has designed specific 'lectin blocking' formulas to help support the body's immune system and metabolism.
This product contains no sugar, salt, gluten, wheat, yeast, corn, soy, eggs or dairy, no preservatives, color or flavors, and no artificial ingredients.
FDA Disclaimer Statement
This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Suggested/Recommended/Usage/Directions
Directions: Two (2) capsules 2-3 daily with meals as a dietary supplement or as directed by a physician.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Deflect B by D'Adamo Personalized Nutrition label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Deflect B by D'Adamo Personalized Nutrition
These are the 6 active ingredients this product is made of. Select any to open its full monograph.
Serving size2 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
N-Acetyl Cysteine
Interacts with294 drugs
N-acetyl cysteine (NAC) is a supplement form of the amino acid cysteine and a building block for the antioxidant glutathione. It has well-established...
N-Acetyl Cysteine monograph & interactionsGum Tragacanth
Interacts with2,022 drugs
Tragacanth is a plant gum used mainly as a thickener and emulsifier in foods, cosmetics, and medicines, and traditionally to soothe the throat and gut...
Gum Tragacanth monograph & interactionsLarch Arabinogalactan
Interacts with121 drugs
Larch arabinogalactan is a soluble fiber from larch trees that is mainly used as a prebiotic and for immune support. Early research is interesting but...
Larch Arabinogalactan monograph & interactionsN-Acetyl-D-Glucosamine
Interacts with170 drugs
Glucosamine is a natural compound found in cartilage and joint fluid, and it is one of the most popular supplements for osteoarthritis, especially of...
N-Acetyl-D-Glucosamine monograph & interactionsPectin
Interacts with23 drugs
Pectin is a natural soluble fiber found in fruits like apples and citrus, and it is widely used in foods and as a fiber supplement. It may modestly he...
Pectin monograph & interactionsFlaxseed Meal
Interacts with597 drugs
Flaxseed is a nutritious food rich in fiber, omega-3 fats (ALA), and plant compounds called lignans. It is most reliably helpful for constipation and...
Flaxseed Meal monograph & interactionsOther (inactive) ingredients: Cellulose, Rice extract, Rice Concentrate. These complete the product’s ingredient list but are not active constituents.
Deflect B by D'Adamo Personalized Nutrition Drug Interactions
HelloPharmacist Interaction Report
Deflect B by D'Adamo Personalized Nutrition contains six active ingredients, and several of them interact with medications.
The most serious interaction involves N-acetyl cysteine with nitroglycerin (a heart medication), which is rated Major — concomitant use can cause severe low blood pressure (hypotension) and severe headaches.
Read the full breakdown — every affected drug type, severity by severity
N-acetyl cysteine also carries Moderate interactions with blood pressure medications (antihypertensives), blood thinners and antiplatelet drugs, chloroquine (an antimalarial), and activated charcoal. Glucosamine (N-acetyl-D-glucosamine) has a Major interaction with warfarin, a blood thinner — it may increase bleeding risk — and Moderate interactions with chemotherapy drugs (topoisomerase II inhibitors).
Pectin may reduce absorption of lovastatin (a cholesterol drug), tetracycline antibiotics, and digoxin (a heart medication), all rated Moderate. Flaxseed Meal carries Moderate interactions with blood pressure drugs, antibiotics, estrogen-based medications, blood thinners, and antidiabetes drugs.
Larch arabinogalactan may interfere with immunosuppressants (Moderate), and gum tragacanth may alter the absorption of oral medications (Moderate).
Altogether, these interactions span 2,191 individual medications. Use the medication checker on this page to verify your exact prescriptions before starting.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Deflect B?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Deflect B interact with 2,213 drugs. Click any drug to see the details.
6 of the 6 ingredients in Deflect B interact with drugs. Each result below shows which ingredient is responsible. Gum Tragacanth Flaxseed Meal N-Acetyl Cysteine N-Acetyl-D-Glucosamine Larch Arabinogalactan Pectin
"phentolamineOraVerse, Rogitine, Ryzumvi
How "phentolamine interacts with Deflect B — through 1 ingredient. Tap an ingredient for the detail:
Gum TragacanthOral Drugs Moderate
Interaction Summary
Theoretically, tragacanth might alter absorption of oral drugs.
Read the full Gum Tragacanth + "phentolamine interaction6-mercaptopurinePurinethol
How 6-mercaptopurine interacts with Deflect B — through 2 ingredients. Tap an ingredient for the detail:
Larch ArabinogalactanImmunosuppressants Moderate
Interaction Summary
Theoretically, larch arabinogalactan might interfere with immunosuppression therapy due to immunostimulant effects.
Read the full Larch Arabinogalactan + 6-mercaptopurine interactionGum TragacanthOral Drugs Moderate
Interaction Summary
Theoretically, tragacanth might alter absorption of oral drugs.
Read the full Gum Tragacanth + 6-mercaptopurine interactionAbacavirZiagen
How Abacavir interacts with Deflect B — through 1 ingredient. Tap an ingredient for the detail:
Gum TragacanthOral Drugs Moderate
Interaction Summary
Theoretically, tragacanth might alter absorption of oral drugs.
Read the full Gum Tragacanth + Abacavir interactionAbacavir Sulfate, Dolutegravir, LamivudineTriumeq
How Abacavir Sulfate, Dolutegravir, Lamivudine interacts with Deflect B — through 1 ingredient. Tap an ingredient for the detail:
Gum TragacanthOral Drugs Moderate
Interaction Summary
Theoretically, tragacanth might alter absorption of oral drugs.
Read the full Gum Tragacanth + Abacavir Sulfate, Dolutegravir, Lamivudine interactionAbacavir, LamivudineEpzicom
How Abacavir, Lamivudine interacts with Deflect B — through 1 ingredient. Tap an ingredient for the detail:
Gum TragacanthOral Drugs Moderate
Interaction Summary
Theoretically, tragacanth might alter absorption of oral drugs.
Read the full Gum Tragacanth + Abacavir, Lamivudine interactionAbciximabReoPro
How Abciximab interacts with Deflect B — through 3 ingredients. Tap an ingredient for the detail:
Gum TragacanthOral Drugs Moderate
Interaction Summary
Theoretically, tragacanth might alter absorption of oral drugs.
Read the full Gum Tragacanth + Abciximab interactionFlaxseed MealAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, using flaxseed in combination with anticoagulant or antiplatelet drugs might have additive effects and increase the risk of bleeding.
Read the full Flaxseed Meal + Abciximab interactionN-acetyl CysteineAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, N-acetyl cysteine might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full N-acetyl Cysteine + Abciximab interactionAbemaciclibVerzenio
How Abemaciclib interacts with Deflect B — through 1 ingredient. Tap an ingredient for the detail:
Gum TragacanthOral Drugs Moderate
Interaction Summary
Theoretically, tragacanth might alter absorption of oral drugs.
Read the full Gum Tragacanth + Abemaciclib interactionAbiraterone
How Abiraterone interacts with Deflect B — through 1 ingredient. Tap an ingredient for the detail:
Gum TragacanthOral Drugs Moderate
Interaction Summary
Theoretically, tragacanth might alter absorption of oral drugs.
Read the full Gum Tragacanth + Abiraterone interactionAbiraterone AcetateYonsa, Zytiga
How Abiraterone Acetate interacts with Deflect B — through 1 ingredient. Tap an ingredient for the detail:
Gum TragacanthOral Drugs Moderate
Interaction Summary
Theoretically, tragacanth might alter absorption of oral drugs.
Read the full Gum Tragacanth + Abiraterone Acetate interactionAbrocitinibCibinqo
How Abrocitinib interacts with Deflect B — through 4 ingredients. Tap an ingredient for the detail:
Gum TragacanthOral Drugs Moderate
Interaction Summary
Theoretically, tragacanth might alter absorption of oral drugs.
Read the full Gum Tragacanth + Abrocitinib interactionLarch ArabinogalactanImmunosuppressants Moderate
Interaction Summary
Theoretically, larch arabinogalactan might interfere with immunosuppression therapy due to immunostimulant effects.
Read the full Larch Arabinogalactan + Abrocitinib interactionFlaxseed MealAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, using flaxseed in combination with anticoagulant or antiplatelet drugs might have additive effects and increase the risk of bleeding.
Read the full Flaxseed Meal + Abrocitinib interactionN-acetyl CysteineAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, N-acetyl cysteine might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full N-acetyl Cysteine + Abrocitinib interactionAcalabrutinibCalquence
How Acalabrutinib interacts with Deflect B — through 1 ingredient. Tap an ingredient for the detail:
Gum TragacanthOral Drugs Moderate
Interaction Summary
Theoretically, tragacanth might alter absorption of oral drugs.
Read the full Gum Tragacanth + Acalabrutinib interactionAcamprosateCampral
How Acamprosate interacts with Deflect B — through 1 ingredient. Tap an ingredient for the detail:
Gum TragacanthOral Drugs Moderate
Interaction Summary
Theoretically, tragacanth might alter absorption of oral drugs.
Read the full Gum Tragacanth + Acamprosate interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Deflect B — through 3 ingredients. Tap an ingredient for the detail:
Gum TragacanthOral Drugs Moderate
Interaction Summary
Theoretically, tragacanth might alter absorption of oral drugs.
Read the full Gum Tragacanth + Acarbose interactionFlaxseed MealAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, flaxseed might have additive effects when used with antidiabetes drugs and increase the risk for hypoglycemia.
Read the full Flaxseed Meal + Acarbose interactionN-acetyl-d-glucosamineAntidiabetes Drugs Minor
Interaction Summary
Despite initial concerns, it is unlikely that glucosamine will interfere with the effects of antidiabetes drugs.
Read the full N-acetyl-d-glucosamine + Acarbose interactionAcebutololRhotral, Sectral
How Acebutolol interacts with Deflect B — through 3 ingredients. Tap an ingredient for the detail:
N-acetyl CysteineAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, N-acetyl cysteine might increase the risk of hypotension when taken with antihypertensive drugs.
Read the full N-acetyl Cysteine + Acebutolol interactionGum TragacanthOral Drugs Moderate
Interaction Summary
Theoretically, tragacanth might alter absorption of oral drugs.
Read the full Gum Tragacanth + Acebutolol interactionFlaxseed MealAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, flaxseed might have additive effects when used with antihypertensive drugs and increase the risk of hypotension.
Read the full Flaxseed Meal + Acebutolol interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Deflect B — through 3 ingredients. Tap an ingredient for the detail:
Gum TragacanthOral Drugs Moderate
Interaction Summary
Theoretically, tragacanth might alter absorption of oral drugs.
Read the full Gum Tragacanth + Acenocoumarol interactionN-acetyl CysteineAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, N-acetyl cysteine might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full N-acetyl Cysteine + Acenocoumarol interactionFlaxseed MealAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, using flaxseed in combination with anticoagulant or antiplatelet drugs might have additive effects and increase the risk of bleeding.
Read the full Flaxseed Meal + Acenocoumarol interactionAcepromazineAtravet
How Acepromazine interacts with Deflect B — through 1 ingredient. Tap an ingredient for the detail:
Gum TragacanthOral Drugs Moderate
Interaction Summary
Theoretically, tragacanth might alter absorption of oral drugs.
Read the full Gum Tragacanth + Acepromazine interactionAcetaminophenChildren's Tylenol, Children's Tylenol Meltaways, Tylenol, Tylenol Ex Strength
How Acetaminophen interacts with Deflect B — through 2 ingredients. Tap an ingredient for the detail:
Gum TragacanthOral Drugs Moderate
Interaction Summary
Theoretically, tragacanth might alter absorption of oral drugs.
Read the full Gum Tragacanth + Acetaminophen interactionN-acetyl-d-glucosamineAcetaminophen (tylenol, Others) Minor
Interaction Summary
Acetaminophen might interfere with the activity of glucosamine sulfate by interacting with the sulfate portion.
Read the full N-acetyl-d-glucosamine + Acetaminophen interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Deflect B — through 4 ingredients. Tap an ingredient for the detail:
Gum TragacanthOral Drugs Moderate
Interaction Summary
Theoretically, tragacanth might alter absorption of oral drugs.
Read the full Gum Tragacanth + Acetaminophen, Aspirin interactionN-acetyl CysteineAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, N-acetyl cysteine might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full N-acetyl Cysteine + Acetaminophen, Aspirin interactionFlaxseed MealAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, using flaxseed in combination with anticoagulant or antiplatelet drugs might have additive effects and increase the risk of bleeding.
Read the full Flaxseed Meal + Acetaminophen, Aspirin interactionN-acetyl-d-glucosamineAcetaminophen (tylenol, Others) Minor
Interaction Summary
Acetaminophen might interfere with the activity of glucosamine sulfate by interacting with the sulfate portion.
Read the full N-acetyl-d-glucosamine + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Deflect B — through 4 ingredients. Tap an ingredient for the detail:
Flaxseed MealAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, using flaxseed in combination with anticoagulant or antiplatelet drugs might have additive effects and increase the risk of bleeding.
Read the full Flaxseed Meal + Acetaminophen, Aspirin, Caffeine interactionGum TragacanthOral Drugs Moderate
Interaction Summary
Theoretically, tragacanth might alter absorption of oral drugs.
Read the full Gum Tragacanth + Acetaminophen, Aspirin, Caffeine interactionN-acetyl CysteineAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, N-acetyl cysteine might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full N-acetyl Cysteine + Acetaminophen, Aspirin, Caffeine interactionN-acetyl-d-glucosamineAcetaminophen (tylenol, Others) Minor
Interaction Summary
Acetaminophen might interfere with the activity of glucosamine sulfate by interacting with the sulfate portion.
Read the full N-acetyl-d-glucosamine + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Brompheniramine, PhenylpropanolamineDimetapp Cold and Flu
How Acetaminophen, Brompheniramine, Phenylpropanolamine interacts with Deflect B — through 2 ingredients. Tap an ingredient for the detail:
Gum TragacanthOral Drugs Moderate
Interaction Summary
Theoretically, tragacanth might alter absorption of oral drugs.
Read the full Gum Tragacanth + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionN-acetyl-d-glucosamineAcetaminophen (tylenol, Others) Minor
Interaction Summary
Acetaminophen might interfere with the activity of glucosamine sulfate by interacting with the sulfate portion.
Read the full N-acetyl-d-glucosamine + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionAcetaminophen, ButalbitalAxocet, Bancap, Bucet, Butex Forte, Esgic CF, Orbivan CF +5 more
How Acetaminophen, Butalbital interacts with Deflect B — through 2 ingredients. Tap an ingredient for the detail:
Gum TragacanthOral Drugs Moderate
Interaction Summary
Theoretically, tragacanth might alter absorption of oral drugs.
Read the full Gum Tragacanth + Acetaminophen, Butalbital interactionN-acetyl-d-glucosamineAcetaminophen (tylenol, Others) Minor
Interaction Summary
Acetaminophen might interfere with the activity of glucosamine sulfate by interacting with the sulfate portion.
Read the full N-acetyl-d-glucosamine + Acetaminophen, Butalbital interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with Deflect B — through 2 ingredients. Tap an ingredient for the detail:
Gum TragacanthOral Drugs Moderate
Interaction Summary
Theoretically, tragacanth might alter absorption of oral drugs.
Read the full Gum Tragacanth + Acetaminophen, Butalbital, Caffeine interactionN-acetyl-d-glucosamineAcetaminophen (tylenol, Others) Minor
Interaction Summary
Acetaminophen might interfere with the activity of glucosamine sulfate by interacting with the sulfate portion.
Read the full N-acetyl-d-glucosamine + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with Deflect B — through 2 ingredients. Tap an ingredient for the detail:
Gum TragacanthOral Drugs Moderate
Interaction Summary
Theoretically, tragacanth might alter absorption of oral drugs.
Read the full Gum Tragacanth + Acetaminophen, Butalbital, Caffeine, Codeine interactionN-acetyl-d-glucosamineAcetaminophen (tylenol, Others) Minor
Interaction Summary
Acetaminophen might interfere with the activity of glucosamine sulfate by interacting with the sulfate portion.
Read the full N-acetyl-d-glucosamine + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Butalbital, CodeineBancap w/ Codeine
How Acetaminophen, Butalbital, Codeine interacts with Deflect B — through 2 ingredients. Tap an ingredient for the detail:
Gum TragacanthOral Drugs Moderate
Interaction Summary
Theoretically, tragacanth might alter absorption of oral drugs.
Read the full Gum Tragacanth + Acetaminophen, Butalbital, Codeine interactionN-acetyl-d-glucosamineAcetaminophen (tylenol, Others) Minor
Interaction Summary
Acetaminophen might interfere with the activity of glucosamine sulfate by interacting with the sulfate portion.
Read the full N-acetyl-d-glucosamine + Acetaminophen, Butalbital, Codeine interactionAcetaminophen, Butalbital, Codeine PhosphatePhrenilin #3
How Acetaminophen, Butalbital, Codeine Phosphate interacts with Deflect B — through 2 ingredients. Tap an ingredient for the detail:
Gum TragacanthOral Drugs Moderate
Interaction Summary
Theoretically, tragacanth might alter absorption of oral drugs.
Read the full Gum Tragacanth + Acetaminophen, Butalbital, Codeine Phosphate interactionN-acetyl-d-glucosamineAcetaminophen (tylenol, Others) Minor
Interaction Summary
Acetaminophen might interfere with the activity of glucosamine sulfate by interacting with the sulfate portion.
Read the full N-acetyl-d-glucosamine + Acetaminophen, Butalbital, Codeine Phosphate interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with Deflect B — through 2 ingredients. Tap an ingredient for the detail:
Gum TragacanthOral Drugs Moderate
Interaction Summary
Theoretically, tragacanth might alter absorption of oral drugs.
Read the full Gum Tragacanth + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionN-acetyl-d-glucosamineAcetaminophen (tylenol, Others) Minor
Interaction Summary
Acetaminophen might interfere with the activity of glucosamine sulfate by interacting with the sulfate portion.
Read the full N-acetyl-d-glucosamine + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with Deflect B — through 2 ingredients. Tap an ingredient for the detail:
Gum TragacanthOral Drugs Moderate
Interaction Summary
Theoretically, tragacanth might alter absorption of oral drugs.
Read the full Gum Tragacanth + Acetaminophen, Caffeine, Codeine interactionN-acetyl-d-glucosamineAcetaminophen (tylenol, Others) Minor
Interaction Summary
Acetaminophen might interfere with the activity of glucosamine sulfate by interacting with the sulfate portion.
Read the full N-acetyl-d-glucosamine + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with Deflect B — through 2 ingredients. Tap an ingredient for the detail:
Gum TragacanthOral Drugs Moderate
Interaction Summary
Theoretically, tragacanth might alter absorption of oral drugs.
Read the full Gum Tragacanth + Acetaminophen, Caffeine, Codeine, Salicylamide interactionN-acetyl-d-glucosamineAcetaminophen (tylenol, Others) Minor
Interaction Summary
Acetaminophen might interfere with the activity of glucosamine sulfate by interacting with the sulfate portion.
Read the full N-acetyl-d-glucosamine + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with Deflect B — through 2 ingredients. Tap an ingredient for the detail:
Gum TragacanthOral Drugs Moderate
Interaction Summary
Theoretically, tragacanth might alter absorption of oral drugs.
Read the full Gum Tragacanth + Acetaminophen, Caffeine, Dihydrocodeine interactionN-acetyl-d-glucosamineAcetaminophen (tylenol, Others) Minor
Interaction Summary
Acetaminophen might interfere with the activity of glucosamine sulfate by interacting with the sulfate portion.
Read the full N-acetyl-d-glucosamine + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Caffeine, IsomethepteneMigralam
How Acetaminophen, Caffeine, Isometheptene interacts with Deflect B — through 2 ingredients. Tap an ingredient for the detail:
Gum TragacanthOral Drugs Moderate
Interaction Summary
Theoretically, tragacanth might alter absorption of oral drugs.
Read the full Gum Tragacanth + Acetaminophen, Caffeine, Isometheptene interactionN-acetyl-d-glucosamineAcetaminophen (tylenol, Others) Minor
Interaction Summary
Acetaminophen might interfere with the activity of glucosamine sulfate by interacting with the sulfate portion.
Read the full N-acetyl-d-glucosamine + Acetaminophen, Caffeine, Isometheptene interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Deflect B with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Gum Tragacanth
Oral Drugs
Theoretically, tragacanth might alter absorption of oral drugs.
Tragacanth contains hydrocolloidal fiber which can decrease, increase, or not affect oral drug absorption. To avoid changes in absorption, take tragacanth 30-60 minutes after oral medications.
Flaxseed Meal
Antibiotic Drugs
Theoretically, antibiotics might interfere with the metabolism of flaxseed constituents, which could potentially alter the effects of flaxseed.
Some potential benefits of flaxseed are thought to be due to its lignan content. Secoisolariciresinol diglucoside (SDG), a major lignan precursor, is found in high concentrations in flaxseed. SDG is converted by bacteria in the colon to the lignans enterolactone and enterodiol. Antibiotics alter the flora of the colon, which could theoretically alter the metabolism of flaxseed.
Anticoagulant/Antiplatelet Drugs
Theoretically, using flaxseed in combination with anticoagulant or antiplatelet drugs might have additive effects and increase the risk of bleeding.
Some clinical evidence suggests that the oil contained in flaxseed can decrease platelet aggregation.
Antidiabetes Drugs
Theoretically, flaxseed might have additive effects when used with antidiabetes drugs and increase the risk for hypoglycemia.
Some clinical research suggests that flaxseed can lower blood glucose levels.
Antihypertensive Drugs
Theoretically, flaxseed might have additive effects when used with antihypertensive drugs and increase the risk of hypotension.
Clinical research shows that daily flaxseed consumption, especially for longer than 12 weeks, modestly reduces blood pressure.
Estrogens
Theoretically, taking flaxseed might decrease the effects of estrogens.
Flaxseed contains lignans with mild estrogenic and possible antiestrogenic effects. The lignans seem to compete with circulating endogenous estrogen and might reduce estrogen binding to estrogen receptors, resulting in an anti-estrogen effect. It is unclear if this effect transfers to exogenously administered estrogens.
N-Acetyl Cysteine
Nitroglycerin
N-acetyl cysteine can increase the risk for hypotension and headaches when taken with intravenous or transdermal nitroglycerin.
Clinical research shows that concomitant administration of N-acetyl cysteine and intravenous or transdermal nitroglycerin can cause severe hypotension and intolerable headaches. Furthermore, in vitro research suggests that N-acetyl cysteine increases the anticoagulant activity of nitroglycerin.
Activated Charcoal
N-acetyl cysteine might reduce the effects of activated charcoal, while activated charcoal might reduce the absorption of N-acetyl cysteine.
N-acetyl cysteine appears to reduce the capacity of activated charcoal to adsorb acetaminophen and salicylic acid. Conversely, although clinical research suggests that although activated charcoal can reduce the absorption of N-acetyl cysteine by up to 40%, it does not seem to reduce its clinical effects. Other clinical evidence suggests that activated charcoal does not affect the absorption of N-acetyl cysteine.
Anticoagulant/Antiplatelet Drugs
Theoretically, N-acetyl cysteine might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Clinical research suggests that intravenous N-acetyl cysteine decreases prothrombin time, prolongs coagulation time, decreases platelet aggregation, and increases blood loss in surgical patients. Furthermore, in vitro research suggests that N-acetyl cysteine increases the anticoagulant activity of nitroglycerin.
Antihypertensive Drugs
Theoretically, N-acetyl cysteine might increase the risk of hypotension when taken with antihypertensive drugs.
Animal research suggests that N-acetyl cysteine potentiates the hypotensive effects of the angiotensin-converting enzyme inhibitors (ACEIs) captopril and enalaprilat. Theoretically, combining N-acetyl cysteine with other antihypertensive drugs might increase the risk of hypotension.
Chloroquine (Aralen)
Theoretically, N-acetyl cysteine might interfere with the antimalarial effects of chloroquine.
Animal research suggests that N-acetyl cysteine might reduce the antimalarial effects of chloroquine by increasing cellular levels of glutathione.
N-Acetyl-D-Glucosamine
Warfarin (Coumadin)
Glucosamine might increase the anticoagulant effects of warfarin and increase the risk of bruising and bleeding.
In two individual case reports, glucosamine/chondroitin combinations were associated with a significant increase in international normalized ratio (INR) in patients previously stabilized on warfarin. In one case, the increase in INR occurred only after tripling the dose of a glucosamine/chondroitin supplement from 500 mg/400 mg daily to 1500/1200 mg daily. Additionally, 20 voluntary case reports to the U.S. Food & Drug Administration (FDA) have linked glucosamine plus chondroitin with increased INR, bruising, and bleeding in patients who were also taking warfarin. There have also been 20 additional case reports to the World Health Organization (WHO) that link glucosamine alone to increased INR in patients taking warfarin. The mechanism of this interaction is unclear. Glucosamine is a small component of heparin, but is not thought to have anticoagulant activity; however, animal research suggests that it might have antiplatelet activity.
Topoisomerase Ii Inhibitors
Theoretically glucosamine may induce resistance to topoisomerase II inhibitors.
In vitro research suggests that glucosamine might induce resistance to etoposide (VP16, VePesid) and doxorubicin (Adriamycin) by reducing inhibition of topoisomerase II, an enzyme required for DNA replication in tumor cells. This effect has not been reported in humans.
Acetaminophen (Tylenol, Others)
Acetaminophen might interfere with the activity of glucosamine sulfate by interacting with the sulfate portion.
Anecdotal reports suggest that adding glucosamine to an acetaminophen regimen might decrease pain control in patients with osteoarthritis. Some research suggests that the sulfate portion of glucosamine sulfate might contribute to its effect in osteoarthritis. Since acetaminophen metabolism requires sulfur and reduces serum sulfate concentrations, acetaminophen could theoretically interfere with the action of glucosamine sulfate. Conversely, the administration of sulfate could theoretically decrease the effectiveness of acetaminophen in sulfate-deficient people by increasing its clearance.
Antidiabetes Drugs
Despite initial concerns, it is unlikely that glucosamine will interfere with the effects of antidiabetes drugs.
In vitro and animal research has suggested that glucosamine might increase insulin resistance or decrease insulin production. This has raised concerns that taking glucosamine might worsen diabetes and decrease the effectiveness of diabetes drugs. However, clinical research suggests that glucosamine does not have adverse effects on blood glucose or glycated hemoglobin (HbA1C) in healthy, obese, or type 2 diabetes patients.
Larch Arabinogalactan
Immunosuppressants
Theoretically, larch arabinogalactan might interfere with immunosuppression therapy due to immunostimulant effects. Immunosuppressant drugs include azathioprine (Imuran), basiliximab (Simulect), cyclosporine (Neoral, Sandimmune), daclizumab (Zenapax), muromonab-CD3 (OKT3, Orthoclone OKT3), mycophenolate (CellCept), tacrolimus (FK506, Prograf), sirolimus (Rapamune), prednisone (Deltasone, Orasone), corticosteroids (glucocorticoids), and other drugs.
Pectin
Digoxin (Lanoxin)
Theoretically, pectin might reduce the absorption of digoxin, potentially decreasing its effectiveness.
A small clinical study shows that taking digoxin with a kaolin-pectin suspension reduces the absorption of digoxin by about 62%. It is unclear if these effects are due to pectin, kaolin, or the combination.
Lovastatin (Mevacor)
Theoretically, pectin might reduce the absorption of lovastatin, potentially decreasing its effectiveness.
Case reports suggest that concomitant use of pectin and lovastatin might reduce the cholesterol-lowering effect of lovastatin, possibly due to reduced intestinal absorption of lovastatin.
Tetracycline Antibiotics
Theoretically, pectin might reduce the absorption of tetracycline antibiotics, potentially decreasing their effectiveness.
A small clinical study shows that taking tetracycline with bismuth subsalicylate in a kaolin-pectin suspension reduces the absorption of tetracycline by about 34%. It is unclear if these effects are due to pectin, kaolin, bismuth subsalicylate, or the combination.
Brand information
Manufacturer and brand details for Deflect B, from the product label.
D'Adamo Personalized Nutrition
See all D'Adamo Personalized Nutrition products- Name
- North American Pharmacal, Inc.
- Street Address
- 213 Danbury Road
- City
- Wilton
- State
- CT
- ZipCode
- 06897
- Phone Number
- 1-877-226-8973
- Web Address
- www.4yourtype.com
Deflect B by D'Adamo Personalized Nutrition: Common Questions
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Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Deflect B’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
N-acetyl Cysteine (nac)
Interacts with 294 drugsN-acetyl cysteine (NAC) is a supplement form of the amino acid cysteine and a building block for the antioxidant glutathione. It has well-established prescription uses for acetaminophen over...
Read the full N-acetyl Cysteine (nac) monograph → Herb & supplement monographTragacanth
Interacts with 2,022 drugsTragacanth is a plant gum used mainly as a thickener and emulsifier in foods, cosmetics, and medicines, and traditionally to soothe the throat and gut. There is very little solid human resea...
Read the full Tragacanth monograph → Herb & supplement monographLarch Arabinogalactan
Interacts with 121 drugsLarch arabinogalactan is a soluble fiber from larch trees that is mainly used as a prebiotic and for immune support. Early research is interesting but limited, and most claims are not yet fi...
Read the full Larch Arabinogalactan monograph → Herb & supplement monographGlucosamine
Interacts with 170 drugsGlucosamine is a natural compound found in cartilage and joint fluid, and it is one of the most popular supplements for osteoarthritis, especially of the knee. The evidence is mixed, with so...
Read the full Glucosamine monograph → Herb & supplement monographPectin
Interacts with 23 drugsPectin is a natural soluble fiber found in fruits like apples and citrus, and it is widely used in foods and as a fiber supplement. It may modestly help with cholesterol, blood sugar, and di...
Read the full Pectin monograph → Herb & supplement monographFlaxseed
Interacts with 597 drugsFlaxseed is a nutritious food rich in fiber, omega-3 fats (ALA), and plant compounds called lignans. It is most reliably helpful for constipation and may modestly lower cholesterol, but evid...
Read the full Flaxseed monograph →Sources & How We Checked
Deflect B's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 202 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
N-acetyl Cysteine (nac) 86 references
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- Jepsen S, Hansen AB. The influence of N-acetylcysteine on the measurement of prothrombin time and activated partial thromboplastin time in healthy subjects. Scand J Clin Lab Invest 1994;54:543-7. PubMed
- van Zandwijk N, Dalesio O, Pastorino U, et al. EUROSCAN, a randomized trial of vitamin A and N-acetylcysteine in patients with head and neck cancer or lung cancer. For the European Organization for Research and Treatment of Cancer Head and Neck and Lung C DOI
- Horowitz RS, Dart RC, Jarvie DR, et al. Placental transfer of N-acetylcysteine following human maternal acetaminophen toxicity. J Toxicol Clin Toxicol 1997;35:447-51.
- Bailey B, McGuigan MA. Management of anaphylactoid reactions to intravenous N-acetylcysteine. Ann Emerg Med 1998;31:710-5. PubMed
- Spiller HA, Krenzelok EP, Grande GA, et al. A prospective evaluation of the effect of activated charcoal before oral N-acetylcysteine in acetaminophen overdose. Ann Emerg Med 1994;23:519-23. PubMed
- Ardissino D, Merlini PA, Savonitto S, et al. Effect of transdermal nitroglycerin or N-acetylcysteine, or both, in the long-term treatment of unstable angina pectoris. J Am Coll Cardiol 1997;29:941-7. PubMed
- Horowitz JD, Henry CA, Syrjanen ML, et al. Nitroglycerine/N-acetylcysteine in the management of unstable angina pectoris. Eur Heart J 1988;9:95-100. PubMed
- Louwerse ES, Weverling GJ, Bossuyt PM, et al. Randomized, double-blind, controlled trial of acetylcysteine in amyotrophic lateral sclerosis. Arch Neurol 1995;52:559-64. PubMed
- Wiklund O, Fager G, Andersson A, et al. N-acetylcysteine treatment lowers plasma homocysteine but not serum lipoprotein(a) levels. Atherosclerosis 1996;119:99-106. PubMed
- De Flora S, Grassi C, Carati L. Attenuation of influenza-like symptomatology and improvement of cell-mediated immunity with long-term N-acetylcysteine treatment. Eur Respir J 1997;10:1535-41. PubMed
- Iversen HK. N-acetylcysteine enhances nitroglycerin-induced headache and cranial arterial responses. Clin Pharmacol Ther 1992;52:125-33. PubMed
- Behr J, Maier K, Degenkolb B, et al. Antioxidative and clinical effects of high-dose N-acetylcysteine in fibrosing alveolitis. Adjunctive therapy to maintenance immunosuppression. Am J Respir Crit Care Med 1997;156:1897-901.
- Tenenbein PK, Sitar DS, Tenenbein M. Interaction between N-acetylcysteine and activated charcoal: implications for the treatment of acetaminophen poisoning. Pharmacotherapy 2001;21:1331-6.
- Arstall MA, Yang J, Stafford I, et al. N-acetylcysteine in combination with nitroglycerin and streptokinase for the treatment of evolving acute myocardial infarction. Safety and biochemical effects. Circulation 1995;92:2855-62.
- Estensen RD, Levy M, Klopp SJ, et al. N-acetylcysteine suppression of the proliferative index in the colon of patients with previous adenomatous colonic polyps. Cancer Lett 1999;147:109-14. PubMed
- Pela R, Calcagni AM, Subiaco S, et al. N-acetylcysteine reduces the exacerbation rate in patients with moderate to severe COPD. Respiration 1999;66:495-500.. PubMed
- Oldemeyer JB, Biddle WP, Wurdeman RL, et al. Acetylcysteine in the prevention of contrast-induced nephropathy after coronary angiography. Am Heart J 2003;146:E23. . PubMed
- Ekins BR, Ford DC, Thompson MI, et al. The effect of activated charcoal on N-acetylcysteine absorption in normal subjects. Am J Emerg Med. 1987;5(6):483-7. PubMed
- Chamberlain JM, Gorman RL, Oderda GM, Klein-Schwartz W, Klein BL. Use of activated charcoal in a simulated poisoning with acetaminophen: a new loading dose for N-acetylcysteine? Ann Emerg Med. 1993;22(9):1398-402. PubMed
- Renzi FP, Donovan JW, Martin TG, Morgan L, Harrison EF. Concomitant use of activated charcoal and N-acetylcysteine. Ann Emerg Med. 1985;14(6):568-72. DOI
- North DS, Peterson RG, Krenzelok EP. Effect of activated charcoal administration on acetylcysteine serum levels in humans. Am J Hosp Pharm. 1981;38(7):1022-4. DOI
- Loscalzo J. N-Acetylcysteine potentiates inhibition of platelet aggregation by nitroglycerin. J Clin Invest. 1985;76(2):703-8. PubMed
- Ruiz FJ, Salom MG, Inglés AC, et al. N-acetyl-L-cysteine potentiates depressor response to captopril and enalaprilat in SHRs. Am J Physiol. 1994;267(3 Pt 2):R767-72. PubMed
- Deharo E, Barkan D, Krugliak M, Golenser J, Ginsburg H. Potentiation of the antimalarial action of chloroquine in rodent malaria by drugs known to reduce cellular glutathione levels. Biochem Pharmacol. 2003;66(5):809-17. PubMed
- Buckley, N. A., Whyte, I. M., O'Connell, D. L., and Dawson, A. H. Oral or intravenous N-acetylcysteine: which is the treatment of choice for acetaminophen (paracetamol) poisoning? J Toxicol.Clin Toxicol. 1999;37(6):759-767.
- Sunman, W., Hughes, A. D., and Sever, P. S. Anaphylactoid response to intravenous acetylcysteine. Lancet 5-16-1992;339(8803):1231-1232. PubMed
- Reynard, K., Riley, A., and Walker, B. E. Respiratory arrest after N-acetylcysteine for paracetamol overdose. Lancet 9-12-1992;340(8820):675. PubMed
- BERNSTEIN, I. L. and AUSDENMOORE, R. W. IATROGENIC BRONCHOSPASM OCCURRING DURING CLINICAL TRIALS OF A NEW MUCOLYTIC AGENT, ACETYLCYSTEINE. Dis.Chest 1964;46:469-473. PubMed
- REAS, H. W. THE USE OF N-ACETYLCYSTEINE IN THE TREATMENT OF CYSTIC FIBROSIS. J Pediatr 1964;65:542-557. PubMed
- Bibi, H., Seifert, B., Oullette, M., and Belik, J. Intratracheal N-acetylcysteine use in infants with chronic lung disease. Acta Paediatr. 1992;81(4):335-339. PubMed
- Jepsen, S., Herlevsen, P., Knudsen, P., Bud, M. I., and Klausen, N. O. Antioxidant treatment with N-acetylcysteine during adult respiratory distress syndrome: a prospective, randomized, placebo-controlled study. Crit Care Med 1992;20(7):918-923. PubMed
- Roes, E. M., Raijmakers, M. T., Boo, T. M., Zusterzeel, P. L., Merkus, H. M., Peters, W. H., and Steegers, E. A. Oral N-acetylcysteine administration does not stabilise the process of established severe preeclampsia. Eur.J Obstet.Gynecol.Reprod.Biol 2006
- Spiller, H. A., Winter, M. L., Klein-Schwartz, W., and Bangh, S. A. Efficacy of activated charcoal administered more than four hours after acetaminophen overdose. J Emerg.Med 2006;30(1):1-5. PubMed
- Tirouvanziam, R., Conrad, C. K., Bottiglieri, T., Herzenberg, L. A., Moss, R. B., and Herzenberg, L. A. High-dose oral N-acetylcysteine, a glutathione prodrug, modulates inflammation in cystic fibrosis. Proc Natl.Acad.Sci U.S.A 3-21-2006;103(12):4628-463
- Niemi, T. T., Munsterhjelm, E., Poyhia, R., Hynninen, M. S., and Salmenpera, M. T. The effect of N-acetylcysteine on blood coagulation and platelet function in patients undergoing open repair of abdominal aortic aneurysm. Blood Coagul.Fibrinolysis 2006;1 PubMed
- Komisarof, J. A., Gilkey, G. M., Peters, D. M., Koudelka, C. W., Meyer, M. M., and Smith, S. M. N-acetylcysteine for patients with prolonged hypotension as prophylaxis for acute renal failure (NEPHRON). Crit Care Med 2007;35(2):435-441. PubMed
- Grimble, G. K. Adverse gastrointestinal effects of arginine and related amino acids. J Nutr 2007;137(6 Suppl 2):1693S-1701S. PubMed
- Berk, M., Copolov, D. L., Dean, O., Lu, K., Jeavons, S., Schapkaitz, I., Anderson-Hunt, M., and Bush, A. I. N-acetyl cysteine for depressive symptoms in bipolar disorder--a double-blind randomized placebo-controlled trial. Biol Psychiatry 9-15-2008;64(6) PubMed
- Shahin, A. Y., Hassanin, I. M., Ismail, A. M., Kruessel, J. S., and Hirchenhain, J. Effect of oral N-acetyl cysteine on recurrent preterm labor following treatment for bacterial vaginosis. Int J Gynaecol.Obstet. 2009;104(1):44-48. PubMed
- Nigwekar, S. U. and Kandula, P. N-acetylcysteine in cardiovascular-surgery-associated renal failure: a meta-analysis. Ann Thorac.Surg 2009;87(1):139-147. PubMed
- Sandilands, E. A. and Bateman, D. N. Adverse reactions associated with acetylcysteine. Clin Toxicol.(Phila) 2009;47(2):81-88. PubMed
- Wijeysundera, D. N., Karkouti, K., Rao, V., Granton, J. T., Chan, C. T., Raban, R., Carroll, J., Poonawala, H., and Beattie, W. S. N-acetylcysteine is associated with increased blood loss and blood product utilization during cardiac surgery. Crit Care Me PubMed
- Holdiness, M. R. Clinical pharmacokinetics of N-acetylcysteine. Clin Pharmacokinet. 1991;20(2):123-134. PubMed
- Dawson, A. H., Henry, D. A., and McEwen, J. Adverse reactions to N-acetylcysteine during treatment for paracetamol poisoning. Med J Aust. 3-20-1989;150(6):329-331.
- Rasmussen, J. B. and Glennow, C. Reduction in days of illness after long-term treatment with N-acetylcysteine controlled-release tablets in patients with chronic bronchitis. Eur.Respir.J 1988;1(4):351-355. DOI
- Walters, M. T., Rubin, C. E., Keightley, S. J., Ward, C. D., and Cawley, M. I. A double-blind, cross-over, study of oral N-acetylcysteine in Sjogren's syndrome. Scand J Rheumatol.Suppl 1986;61:253-258.
- Cato, A., Goldstein, I., and Millman, M. A double-blind parallel study of acetylcysteine-isoproterenol and saline-isoproterenol in patients with chronic obstructive lung disease. J Int Med Res 1977;5(3):175-183. PubMed
- Parr, G. D. and Huitson, A. Oral Fabrol (oral N-acetyl-cysteine) in chronic bronchitis. Br.J.Dis.Chest 1987;81(4):341-348.
- Dano, G. Bronchospasm caused by acetylcysteine in children with bronchial asthma. Acta Allergol. 1971;26(3):181-190. DOI
- Howatt, W. F. and DeMuth, G. R. A double-blind study of the use of acetylcysteine in patients with cystic fibrosis. Univ Mich.Med Cent.J 1966;32(2):82-85.
- Millman, M. and Grundon, W. Use of acetylcysteine in bronchial asthma and emphysema. J Asthma Res 1969;6(4):199-209. PubMed
- Vale, J. A. and Wheeler, D. C. Anaphylactoid reaction to acetylcysteine. Lancet 10-30-1982;2(8305):988.
- Mant, T. G., Tempowski, J. H., Volans, G. N., and Talbot, J. C. Adverse reactions to acetylcysteine and effects of overdose. Br Med J (Clin Res Ed) 7-28-1984;289(6439):217-219. PubMed
- Myers, C., Bonow, R., Palmeri, S., Jenkins, J., Corden, B., Locker, G., Doroshow, J., and Epstein, S. A randomized controlled trial assessing the prevention of doxorubicin cardiomyopathy by N-acetylcysteine. Semin.Oncol 1983;10(1 Suppl 1):53-55.
- Miller, L. F. and Rumack, B. H. Clinical safety of high oral doses of acetylcysteine. Semin.Oncol 1983;10(1 Suppl 1):76-85.
- Boman, G., Backer, U., Larsson, S., Melander, B., and Wahlander, L. Oral acetylcysteine reduces exacerbation rate in chronic bronchitis: report of a trial organized by the Swedish Society for Pulmonary Diseases. Eur J Respir.Dis 1983;64(6):405-415.
- Tattersall, A. B., Bridgman, K. M., and Huitson, A. Irish general practice study of acetylcysteine (Fabrol) in chronic bronchitis. J Int Med Res 1984;12(2):96-101. PubMed
- Jackson, I. M., Barnes, J., and Cooksey, P. Efficacy and tolerability of oral acetylcysteine (Fabrol) in chronic bronchitis: a double-blind placebo controlled study. J Int Med Res 1984;12(3):198-206. PubMed
- Ho, S. W. and Beilin, L. J. Asthma associated with N-acetylcysteine infusion and paracetamol poisoning: report of two cases. Br Med J (Clin Res Ed) 9-24-1983;287(6396):876-877. PubMed
- Vale, J. A. and Buckley, B. M. Asthma associated with N-acetylcysteine infusion and paracetamol poisoning. Br Med J (Clin Res Ed) 10-22-1983;287(6400):1223. PubMed
- Bateman, D. N., Woodhouse, K. W., and Rawlins, M. D. Adverse reactions to N-acetylcysteine. Hum Toxicol. 1984;3(5):393-398. PubMed
- Gervais, S., Lussier-Labelle, F., and Beaudet, G. Anaphylactoid reaction to acetylcysteine. Clin Pharm 1984;3(6):586-587.
- Tattersall, A. B., Bridgman, K. M., and Huitson, A. Acetylcysteine (Fabrol) in chronic bronchitis--a study in general practice. J Int Med Res 1983;11(5):279-284. PubMed
- Casola, G. and vanSonnenberg, E. Skin damage from acetylcysteine leak during percutaneous abscess drainage. Radiology 1984;152(1):233. PubMed
- Aylward, M., Maddock, J., and Dewland, P. Clinical evaluation of acetylcysteine in the treatment of patients with chronic obstructive bronchitis: a balanced double-blind trial with placebo control. Eur.J Respir.Dis.Suppl 1980;111:81-89.
- Long-term oral acetylcysteine in chronic bronchitis. a double-blind controlled study. Eur.J Respir.Dis.Suppl 1980;111:93-108.
- Chan, T. Y. and Critchley, J. A. Adverse reactions to intravenous N-acetylcysteine in Chinese patients with paracetamol (acetaminophen) poisoning. Hum Exp.Toxicol. 1994;13(8):542-544. PubMed
- Hansen, N. C., Skriver, A., Brorsen-Riis, L., Balslov, S., Evald, T., Maltbaek, N., Gunnersen, G., Garsdal, P., Sander, P., Pedersen, J. Z., and . Orally administered N-acetylcysteine may improve general well-being in patients with mild chronic bronchiti
- Reid, M. B., Stokic, D. S., Koch, S. M., Khawli, F. A., and Leis, A. A. N-acetylcysteine inhibits muscle fatigue in humans. J Clin Invest 1994;94(6):2468-2474. PubMed
- Chirkov, Y. Y. and Horowitz, J. D. N-Acetylcysteine potentiates nitroglycerin-induced reversal of platelet aggregation. J Cardiovasc.Pharmacol 1996;28(3):375-380. PubMed
- Hershkovitz, E., Shorer, Z., Levitas, A., and Tal, A. Status epilepticus following intravenous N-acetylcysteine therapy. Isr.J Med Sci 1996;32(11):1102-1104.
- Stavem, K. [Anaphylactic reaction to N-acetylcysteine after poisoning with paracetamol]. Tidsskr.Nor Laegeforen. 5-30-1997;117(14):2038-2039.
- Walton, N. G., Mann, T. A., and Shaw, K. M. Anaphylactoid reaction to N-acetylcysteine. Lancet 12-15-1979;2(8155):1298. PubMed
- Perry, H. E. and Shannon, M. W. Efficacy of oral versus intravenous N-acetylcysteine in acetaminophen overdose: results of an open-label, clinical trial. J Pediatr 1998;132(1):149-152. PubMed
- Kory, R. C., Hirsch, S. R., and Giraldo, J. Nebulization of N-acetylcysteine combined with a bronchodilator in patients with chronic bronchitis. A controlled study. Chest 1968;54(6):504-509. PubMed
- Nahir, A. M., Scharf, J. M., and Szargel, R. Effects of oral N-acetylcysteine on both ocular and oral manifestations of Sjogren's Syndrome. Curr Ther Res 1989;46:187-192.
- Charley, G., Dean, B. S., and Krenzelok, E. P. Oral N-acetylcysteine-induced urticaria: a case report. Vet.Hum Toxicol. 1987;29:477.
- Jenkins DD, Wiest DB, Mulvihill DM, et al. Fetal and neonatal effects of N-acetylcysteine when used for neuroprotection in maternal chorioamnionitis. J Pediatr. 2016 Jan;168:67-76.e6. PubMed
- Costa DLC, Diniz JB, Requena G, et al. Randomized double-blind, placebo-controlled trial of N-acetylcysteine augmentation for treatment-resistant obsessive-compulsive disorder. J Clin Psychiatry. 2017 Jul;78(7):e799-e773.
- Kranzer K, Elamin WF, Cox H, Seddon JA, Ford N, Drobniewski F. A systematic review and meta-analysis of the efficacy and safety of N-acetylcysteine in preventing aminoglycoside-induced ototoxicity: implications for the treatment of multidrug-resistant TB.
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See these in context on the N-acetyl Cysteine (nac) monograph →
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