Interactions on record — worth a quick check against your medications. Check your meds →
Dietary supplement

Digestive Advantage Daily Probiotic Gummies Ingredients & Drug Interactions

by Schiff

Digestive Advantage Daily Probiotic Gummies label
See full label image
Gummy Or Jelly Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Digestive Advantage Daily Probiotic Gummies against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Digestive Advantage Daily Probiotic Gummies is a dietary supplement by Schiff with 1 active ingredient. Its ingredients are commonly taken for constipation, irritable bowel syndrome (ibs), diarrhea.Based on those ingredients, 182 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are BC30 Bacillus coagulans GBI-30, 6086. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Digestive Advantage Daily Probiotic Gummies by Schiff

Ask about any prescription or over-the-counter medication and we check it for interactions with Digestive Advantage Daily Probiotic Gummies by Schiff — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
Prefer a human? Send your question to our licensed pharmacists — free, answered by email within 24 hours.

HelloPharmacist Scorecard of Digestive Advantage Daily Probiotic Gummies by Schiff

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 23, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 1 active ingredient.

Digestive Advantage Daily Probiotic Gummies contains one active ingredient: BC30 Bacillus coagulans GBI-30, 6086, a live probiotic (beneficial bacteria) intended to support digestive health. The gummies also contain inactive ingredients including corn syrup, sugar, gelatin, and natural flavors to make them taste good and hold their shape.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: digestive health and reduce abdominal discomfort.
  • We looked for evidence on: Constipation, Diarrhea, Dyspepsia, Flatulence, Irritable bowel syndrome (IBS), bloating — and 1 related terms.
  • The strongest evidence on file: Bacillus Coagulans is rated "Possibly Effective" for Constipation (Natural Medicines).
  • Also on file: Bacillus Coagulans is rated "Possibly Effective" for Irritable bowel syndrome (IBS).
  • Also on file: Bacillus Coagulans is rated "Insufficient Reliable Evidence To Rate" for Antibiotic-associated diarrhea, Dyspepsia, Flatulence, Rotaviral diarrhea, and more.

The evidence for Bacillus coagulans is mixed. It's rated possibly effective for constipation and for irritable bowel syndrome (IBS)—meaning there's some promising data, but it's not conclusive yet.

For antibiotic-associated diarrhea, athletic performance, cancer prevention, and fatty liver disease, we don't have enough reliable evidence to say whether it works. Talk with your doctor about whether a probiotic makes sense for your particular digestive concern.

The evidence, ingredient by ingredient Bacillus Coagulans

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Bacillus coagulans is generally well tolerated in healthy adults, but the evidence and quality of probiotic products vary considerably. The safety data overall isn't as robust as we'd like, so it's worth checking with your doctor or pharmacist before you start, especially if you have a weakened immune system, a central line or other indwelling catheter, or are severely ill—in those cases, live probiotics carry a small risk of infection.

There isn't enough data on file about use in pregnancy and breastfeeding, so talk with your doctor or pharmacist for personalized advice if you're pregnant, nursing, or planning to become pregnant.

Side effects, ingredient by ingredient Bacillus Coagulans

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Bacillus Coagulans.
  • The most serious interaction on file is rated Moderate.
  • For scale: 182 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check your antibiotic medications before taking this probiotic. Antibiotics can kill the live bacteria in the supplement and reduce its effectiveness, so separate them by several hours.

If you take any antibiotics, mention this product to your doctor or pharmacist so they can help you time them correctly.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

If you have occasional constipation or IBS and want to try a probiotic, this one has some evidence behind it for those uses. Just avoid taking it at the same time as antibiotics—space them several hours apart.

Before you start, especially if you have a compromised immune system or are very ill, check with your own doctor or pharmacist to make sure it's right for you.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Apr 25, 2019.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Digestive Advantage Daily Probiotic Gummies, straight from the product label.

Brand Schiff
Barcode (UPC) 020525183675
Net contents 60 Gummy(ies)
Market status On market
Date entered into DSLD Apr 25, 2019
DSLD ID 202244
Product type Non-nutrient/non-botanical
Supplement form Gummy Or Jelly
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Children 4 or More Years of Age, Adult (18 - 50 Years), Gluten Free, Children more than 1 but less than 4
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Digestive Advantage Daily Probiotic Gummies by Schiff, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Gummy(ies)
Maximum serving Sizes:
2 Gummy(ies)
Servings per container
30
UPC/BARCODE
020525183675
IngredientAmount% DV
Calories20 Calorie(s)--
Total Carbohydrates5 Gram(s)3%, 2%
Added Sugars3 Gram(s)12%, 6%
Total Sugars3 Gram(s)--
BC30 Bacillus coagulans GBI-30, 60860 NP--

Other ingredients: Corn Syrup, Sugar, Water, Gelatin, Citric Acid, Lactic Acid, Pectin, Natural flavors, Colors

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Probiotic Gummy #1 Brand Infused with BC30

Why does Digestive Advantage survive? Only Digestive Advantage uses BC30, a unique patented probiotic.

Contains soy.

General Statements

Why Daily Probiotic Gummies? Probiotics are good bacteria that promote digestive health and help reduce minor abdominal discomfort, and occasional bloating. With continued use, Digestive Advantage Daily Probiotic Gummies are ideal for long-term digestive support.

Why use Digestive Advantage? Many probiotics don't survive through the stomach's acid. Digestive Advantage does! It survives stomach acid 100x better; one serving a day delivers more live good bacteria to your digestive system than leading probiotics and yogurts to naturally support your digestive health.

Survives 100x Better vs. Leading Probiotics

A natural protein shell protects our probiotic allowing it to survive stomach acid so more live good bacteria can get to your digestive tract and reach the intestines, where you need them most. Probiotics in your intestines promote a healthy digestive and immune system.

Based on 52w Nielsen data through 9/23/17 Based on survivability testing vs. yogurts and leading probiotics including a high potency probiotic brand offering 50 billion live cultures.

Since 1936

Probiotic survives stomach acid 100x better

Protected with a natural protein shell so it can deliver more live good bacteria to your digestive tract For overall digestive & immune health Helps lessen minor abdominal discomfort & occasional bloating

Survives Better Than 50 Billion

Great tasting natural fruit flavors

vs. product offering 50 billion live cultures

rb Health Hygiene Home

Brand IP Statement(s)

Powered by Digestive & Immune Health Ganeden BC30 Probiotic

2018 RB

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Directions: Adults and children 3 years of age and older: Chew two (2) gummies once or twice a day. Not for children under 3 years of age due to the risk of choking. Chew thoroughly before swallowing.

Precautions

Not for children under 3 years of age due to the risk of choking.

Contains soy.

Note: If pregnant, breastfeeding, or on medication, consult your physician before using this product.

Keep out of reach of children. Always consult your pediatrician before giving your child dietary supplements.

Protected with a tamper evident seal. Do not use if seal under cap is broken or missing.

Storage

Store in a cool, dry place with lid tightly closed.

Formulation

Gluten free

Seals/Symbols

Gluten free

General

112917 3044111

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Digestive Advantage Daily Probiotic Gummies by Schiff label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Digestive Advantage Daily Probiotic Gummies label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Digestive Advantage Daily Probiotic Gummies by Schiff

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 Gummy(ies) Dosage formGummy Or Jelly Servings per container30 Amounts shown are per serving.

BC30 Bacillus coagulans GBI-30, 6086

Interacts with
182 drugs
0 NP per serving

Bacillus coagulans is a spore-forming probiotic that survives stomach acid well and may help with some digestive problems such as IBS, constipation, a...

BC30 Bacillus coagulans GBI-30, 6086 monograph & interactions

Other (inactive) ingredients: Corn Syrup, Sugar, Water, Gelatin, Citric Acid, Lactic Acid, Pectin, Natural flavors, Colors. These complete the product’s ingredient list but are not active constituents.

Interaction report

Digestive Advantage Daily Probiotic Gummies by Schiff Drug Interactions

Want to check YOUR meds against Digestive Advantage Daily Probiotic Gummies?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
182Drugs
182 Moderate

Ingredients driving the most interactions

BC30 Bacillus coagulans GBI-30, 6086 182

Individual Drug Interactions

The ingredients in Digestive Advantage Daily Probiotic Gummies interact with 182 drugs. Click any drug to see the details.

1 of the 1 ingredient in Digestive Advantage Daily Probiotic Gummies interact with drugs. Each result below shows which ingredient is responsible. BC30 Bacillus coagulans GBI-30, 6086

Each ingredient & the kinds of drugs it affects

For each ingredient in Digestive Advantage Daily Probiotic Gummies with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

BC30 Bacillus coagulans GBI-30, 60861 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B. coagulans.
B. coagulans preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and B. coagulans preparations by at least two hours.

Likelihood Probable Evidence D
BC30 Bacillus coagulans GBI-30, 6086 full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Digestive Advantage Daily Probiotic Gummies, from the product label.

Schiff

See all Schiff products
Name
Reckitt Benckiser
City
Parsippany
State
NJ
ZipCode
07054-0224
Phone Number
1-800-526-6251
Web Address
www.digestiveadvantage.com
Pharmacist Counseling Corner

Digestive Advantage Daily Probiotic Gummies by Schiff: Common Questions

Does Digestive Advantage Daily Probiotic Gummies by Schiff interact with any medications?
Yes. Based on its ingredients, Digestive Advantage Daily Probiotic Gummies has a known interaction with 182 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Digestive Advantage Daily Probiotic Gummies contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this probiotic work if I'm also taking an antibiotic?
Not if you take them at the same time. Antibiotics kill the live bacteria in the probiotic, which defeats the purpose. Separate them by a few hours—for example, take your antibiotic in the morning and your probiotic in the evening. Your pharmacist can help you figure out the best schedule.
Is this probiotic safe for me if I have a weakened immune system?
Probably not without talking to your doctor first. Live probiotics carry a small risk of infection in people with very weak immune systems, central lines, or severe illness. If that's your situation, get personalized advice from your doctor or pharmacist before starting.
Can I take this while pregnant or breastfeeding?
There isn't enough safety data on file to say either way. Talk with your doctor or pharmacist for personalized advice—they can weigh the potential benefits against any risks based on your individual situation.
Will this actually help my IBS or constipation?
There's some promising evidence that Bacillus coagulans may help with both, but it's not a sure thing—the research isn't conclusive yet. Results vary from person to person, so it's worth trying if your doctor thinks it makes sense, but manage your expectations.
What exactly is BC30 Bacillus coagulans?
It's a strain of beneficial bacteria that lives in your gut and theoretically supports digestive health. Unlike some probiotics, it can form spores, which may make it more stable during storage and transit through your stomach acid.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Digestive Advantage Daily Probiotic Gummies is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Digestive Advantage Daily Probiotic Gummies label
Go deeper

The Full Monographs Behind Digestive Advantage Daily Probiotic Gummies’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Bacillus Coagulans

Interacts with 182 drugs

Bacillus coagulans is a spore-forming probiotic that survives stomach acid well and may help with some digestive problems such as IBS, constipation, and certain types of diarrhea. The eviden...

Read the full Bacillus Coagulans monograph →
Sources

Sources & How We Checked

Digestive Advantage Daily Probiotic Gummies's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 20 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Bacillus Coagulans 20 references
  1. Saxelin M, Chuang NH, Chassy B, et al. Lactobacilli and bacteremia in southern Finland 1989-1992. Clin Infect Dis 1996;22:564-6. PubMed
  2. Tynkkynen S, Singh KV, Varmanen P. Vancomycin resistance factor of Lactobacillus rhamnosus GG in relation to enterococcal vancomycin resistance (van) genes. Int J Food Microbiol 1998;41:195-204. PubMed
  3. Klein G, Zill E, Schindler R, et al. Peritonitis associated with vancomycin-resistant Lactobacillus rhamnosus in a continuous ambulatory peritoneal dialysis patient; organism identification, antibiotic therapy, and case report. J Clin Microbiol 1998;36:
  4. Kalima P, Masterton RG, Roddie PH, et al. Lactobacillus rhamnosus infection in a child following bone marrow transplant. J Infect 1996;32:165-7. PubMed
  5. Goldin BR. Health Benefits of probiotics. Br J Nutr 1998;80:S203-7. DOI
  6. Rautio M, Jousimies-Somer H, Kauma H, et al. Liver abscess due to Lactobacillus rhamnosus strain indistinguishable from L. rhamnosus strain GG. Clin Infect Dis 1999;28:1159-60.
  7. MacGregor G, Smith AJ, Thakker B, Kinsella J. Yoghurt biotherapy: contraindicated in immunosuppressed patients? Postgrad Med J 2002;78:366-7. PubMed
  8. Land MH, Rouster-Stevens K, Woods CR, et al. Lactobacillus sepsis associated with probiotic therapy. Pediatrics 2005;115:178-81.
  9. De Groote MA, Frank DN, Dowell E, et al. Lactobacillus rhamnosus GG bacteremia associated with probiotic use in a child with short gut syndrome. Pediatr Infect Dis J 2005;24:278-80. PubMed
  10. Vahabnezhad E, Mochon AB, Wozniak LJ, Ziring DA. Lactobacillus bacteremia associated with probiotic use in a pediatric patient with ulcerative colitis. J Clin Gastroenterol. 2013;47(5):437-9. PubMed
  11. Pruccoli G, Silvestro E, Pace Napoleone C, Aidala E, Garazzino S, Scolfaro C. Are probiotics safe? Bifidobacterium bacteremia in a child with severe heart failure. Infez Med. 2019;27(2):175-178.
  12. Sendil S, Shrimanker I, Mansoora Q, Goldman J, Nookala VK. Lactobacillus rhamnosus bacteremia in an immunocompromised renal transplant patient. Cureus. 2020;12(2):e6887. PubMed
  13. Albarillo FS, Shah U, Joyce C, Slade D. Lactobacillus rhamnosus Infection: A single-center 4-year descriptive analysis. J Glob Infect Dis. 2020;12(3):119-123. PubMed
  14. Pasala S, Singer L, Arshad T, Roach K. Lactobacillus endocarditis in a healthy patient with probiotic use. IDCases. 2020;22:e00915. PubMed
  15. Agrawal S, Tuchman ES, Bruce MJ, Theodorou ME. Fatal Lactobacillus endocarditis in a patient with transcatheter aortic valve replacement. BMJ Case Rep. 2020;13(11):e236835.
  16. Antoun M, Hattab Y, Akhrass FA, Hamilton LD. Uncommon pathogen, Lactobacillus, causing infective endocarditis: Case report and review. Case Rep Infect Dis. 2020;2020:8833948. PubMed
  17. Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
  18. Franko B, Vaillant M, Recule C, Vautrin E, et al. Lactobacillus paracasei endocarditis in a consumer of probiotics. Med Mal Infect. 2013;43(4):171-3. PubMed
  19. Campbell RE, Miller A, Afroze A. Native valve endocarditis secondary to Lactobacillus paracasei bacteremia. Consultant. 2020;60(9):27-8. DOI
  20. Kato K, Funabashi N, Takaoka H, et al. Lactobacillus paracasei endocarditis in a consumer of probiotics with advanced and severe bicuspid aortic valve stenosis complicated with diffuse left ventricular mid-layer fibrosis. Int J Cardiol. 2016;224:157-161. PubMed

See these in context on the Bacillus Coagulans monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring
Supplement interaction checker › Check any supplement or product against your medications Drug–drug interactions › Check two or more of your medications against each other Browse medications A–Z › Every drug we've checked against herbs & supplements NDC & pricing lookup › Find a drug’s NDCs, packaging and costs Ask a pharmacist › Free, personal answer from our licensed team