Interactions on record — worth a quick check against your medications. Check your meds →
Dietary supplement

Digestive Advantage Kids Daily Probiotics Ingredients & Drug Interactions

by Schiff

Gummy Or Jelly Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Digestive Advantage Kids Daily Probiotics is a dietary supplement by Schiff with 1 active ingredient. Its ingredients are commonly taken for constipation, irritable bowel syndrome (ibs), diarrhea.Based on those ingredients, 182 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are BC30 Bacillus coagulans GBI-30, 6086. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Digestive Advantage Kids Daily Probiotics by Schiff

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: BC30 Bacillus coagulans GBI-30, 6086, a live probiotic strain. Probiotics are beneficial bacteria meant to support digestive health.

The gummy or jelly is rounded out with inactive ingredients like corn syrup, sugar, gelatin, citric acid, and pectin — the standard stuff that gives it flavor, texture, and shelf stability.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: supports overall digestive health and minor discomfort.
  • We looked for evidence on: Constipation, Diarrhea, Dyspepsia, Flatulence, Irritable bowel syndrome (IBS), bloating — and 2 related terms.
  • The strongest evidence on file: Bacillus Coagulans is rated "Possibly Effective" for Constipation (Natural Medicines).
  • Also on file: Bacillus Coagulans is rated "Possibly Effective" for Irritable bowel syndrome (IBS).
  • Also on file: Bacillus Coagulans is rated "Insufficient Reliable Evidence To Rate" for Antibiotic-associated diarrhea, Diarrhea, Dyspepsia, Flatulence, and more.

The evidence shows BC30 Bacillus coagulans is possibly effective for constipation and irritable bowel syndrome (IBS). For antibiotic-associated diarrhea, athletic performance, cancer, and nonalcoholic fatty liver disease, the evidence isn't established enough to rate.

If you're considering this for a specific condition, talk with your doctor or pharmacist about whether the evidence supports it for your situation.

The evidence, ingredient by ingredient Bacillus Coagulans

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

BC30 Bacillus coagulans is generally well tolerated in healthy adults, though the evidence and product quality can vary between brands and batches. The manufacturer advises you to talk with your doctor before using, since safety data in children isn't robust.

There is a theoretical concern that live probiotics could cause infection in patients with central lines, severe illness, weakened immune systems, or in very premature infants — but this risk is mainly in those specific high-risk groups, not in otherwise healthy kids. For pregnancy and breastfeeding, there isn't enough data on file to say either way; check with your doctor or pharmacist for personalized guidance.

Side effects, ingredient by ingredient Bacillus Coagulans

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Bacillus Coagulans.
  • The most serious interaction on file is rated Moderate.
  • For scale: 182 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Antibiotics are the main concern — don't take them at the same time as this probiotic. Antibiotics will kill the beneficial bacteria in the product, making it less effective.

Separate the doses by a few hours (check with your pharmacist for the best timing). If your child is taking any antibiotic, mention this product when you fill the prescription so your pharmacist can advise on spacing.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This probiotic may help with constipation or IBS symptoms in kids, but the evidence is modest. The main thing to watch for is spacing it apart from antibiotics — they'll interfere with each other.

If your child is premature, severely ill, or has a weakened immune system, talk with their doctor first. Run your child's exact medications through the checker on this page, and confirm the timing plan with your pharmacist or doctor.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jan 22, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Digestive Advantage Kids Daily Probiotics, straight from the product label.

Brand Schiff
Barcode (UPC) 020525901255
Net contents 80 Gummy(ies)
Market status On market
Date entered into DSLD Jan 22, 2021
DSLD ID 240956
Product type Non-nutrient/non-botanical
Supplement form Gummy Or Jelly
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Children 4 or More Years of Age, Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Digestive Advantage Kids Daily Probiotics by Schiff, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Gummy(ies)
Maximum serving Sizes:
4 Gummy(ies)
Servings per container
20
UPC/BARCODE
020525901255
IngredientAmount% DV
Calories40 Calorie(s), 20 Calorie(s)--
Total Carbohydrates10 Gram(s), 5 Gram(s)4%, 2%
Added Sugars7 Gram(s), 3 Gram(s)14%, 6%
Total Sugars7 Gram(s), 3 Gram(s)--
BC30 Bacillus coagulans GBI-30, 608613.32 mg, 6.66 mg--

Other ingredients: Corn Syrup, Sugar, Water, Gelatin, Citric Acid, Lactic Acid, Pectin, Natural flavors, Colors

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Happy tummies, happy kids #1 Probiotic gummy brand Infused with BC30 Great tasting probiotic gummies, easy to fit into your kid's routine.

Based on 52w Nielsen data through 03/02/19. Based on median survivability of Digestive Advantage probiotic vs. leading yogurts in a simulated gastric environment.

Schiff since 1963

Servings per container 40; 20

Formulation

Our probiotic supports overall digestive health, helps lessen minor abdominal discomfort and occasional bloating. 2=8 Two gummies survive as well as 8+ yogurts Schiff Quality Guarantee Purity Freshness Potency Labeled potency of live culture

Probiotic survives stomach acid 100x better Probiotic protected with a natural protein shell to deliver more live bacteria to your kid's digestive tract

Gluten free

Survives better than 50 billion

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Formula

Great tasting natural fruit flavors

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Directions: Adults and children 4 years of age and older. Chew two (2) gummies once a day for immune health benefits. Chew four (4) gummies once a day for immune health and digestive health benefits including minor abdominal discomfort and occasional bloating. Take at or near mealtime, chew thoroughly before swallowing.

Precautions

Not for children under 4 years of age due to risk of choking.

Contains soy.

If pregnant, breastfeeding, on medication, or are immunocompromised consult your physician before using this product.

Keep out of reach of children. Always consult your pediatrician before giving your child dietary supplements.

Protected with a tamper evident seal. Do not use if seal under cap is broken or missing.

Brand IP Statement(s)

2019 RB Health

rb Health Hygiene Home Patents: www. rb.com/patents

Storage

Store in a cool, dry place with lid tightly closed.

See for yourself

Digestive Advantage Kids Daily Probiotics by Schiff label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Digestive Advantage Kids Daily Probiotics by Schiff

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 Gummy(ies) Dosage formGummy Or Jelly Servings per container20 Amounts shown are per serving.

BC30 Bacillus coagulans GBI-30, 6086

Interacts with
182 drugs
13.32 mg per serving

Bacillus coagulans is a spore-forming probiotic that survives stomach acid well and may help with some digestive problems such as IBS, constipation, a...

BC30 Bacillus coagulans GBI-30, 6086 monograph & interactions

Other (inactive) ingredients: Corn Syrup, Sugar, Water, Gelatin, Citric Acid, Lactic Acid, Pectin, Natural flavors, Colors. These complete the product’s ingredient list but are not active constituents.

Interaction report

Digestive Advantage Kids Daily Probiotics by Schiff Drug Interactions

Want to check YOUR meds against Digestive Advantage Kids Daily Probiotics?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
182Drugs
182 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Digestive Advantage Kids Daily Probiotics with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

BC30 Bacillus coagulans GBI-30, 60861 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B. coagulans.
B. coagulans preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and B. coagulans preparations by at least two hours.

Likelihood Probable Evidence D
The maker

Brand information

Manufacturer and brand details for Digestive Advantage Kids Daily Probiotics, from the product label.

Schiff

See all Schiff products
Name
RB Health (US) LLC
City
Parsippany
State
NJ
ZipCode
07054-0224
Phone Number
1-800-526-6251
Web Address
www.digestiveadvantage.com
Pharmacist Counseling Corner

Digestive Advantage Kids Daily Probiotics by Schiff: Common Questions

Does Digestive Advantage Kids Daily Probiotics by Schiff interact with any medications?
Yes. Based on its ingredients, Digestive Advantage Kids Daily Probiotics has a known interaction with 182 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Digestive Advantage Kids Daily Probiotics contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this probiotic work if my child is on an antibiotic?
Not if you take them together. Antibiotics kill bacteria — including the good ones in this product. Ask your pharmacist to help you space the doses a few hours apart so the probiotic can do its job.
Is BC30 Bacillus coagulans the same as other probiotics?
It's one specific probiotic strain, so it's not the same as all other probiotics. The evidence supports it specifically for constipation and IBS, though the overall data is still modest. Different strains have different effects.
Can I give this to my very young child or premature infant?
There's a theoretical risk of infection in premature or severely ill infants, and safety data in young children is limited. Talk with your child's doctor before starting, especially if they were born early or have any health concerns.
What does BC30 Bacillus coagulans actually do?
It's a live beneficial bacterium meant to support digestive health. The evidence shows it may help with constipation and irritable bowel syndrome, though the data isn't strong for other claims like boosting athletic performance or treating liver disease.
Are there fillers or added stuff I should know about?
Yes — the gummy base includes corn syrup, sugar, gelatin, citric acid, and pectin for flavor and texture. If your child has allergies or sensitivities to any of these, check the label or ask your pharmacist.
Is this safe to use while breastfeeding?
The safety data for this product while breastfeeding isn't established in our records. Check with your doctor or pharmacist about whether it's right for you during that time.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Digestive Advantage Kids Daily Probiotics is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Digestive Advantage Kids Daily Probiotics label
Go deeper

The Full Monographs Behind Digestive Advantage Kids Daily Probiotics’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Digestive Advantage Kids Daily Probiotics's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 20 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Bacillus Coagulans 20 references
  1. Saxelin M, Chuang NH, Chassy B, et al. Lactobacilli and bacteremia in southern Finland 1989-1992. Clin Infect Dis 1996;22:564-6. PubMed
  2. Tynkkynen S, Singh KV, Varmanen P. Vancomycin resistance factor of Lactobacillus rhamnosus GG in relation to enterococcal vancomycin resistance (van) genes. Int J Food Microbiol 1998;41:195-204. PubMed
  3. Klein G, Zill E, Schindler R, et al. Peritonitis associated with vancomycin-resistant Lactobacillus rhamnosus in a continuous ambulatory peritoneal dialysis patient; organism identification, antibiotic therapy, and case report. J Clin Microbiol 1998;36:
  4. Kalima P, Masterton RG, Roddie PH, et al. Lactobacillus rhamnosus infection in a child following bone marrow transplant. J Infect 1996;32:165-7. PubMed
  5. Goldin BR. Health Benefits of probiotics. Br J Nutr 1998;80:S203-7. DOI
  6. Rautio M, Jousimies-Somer H, Kauma H, et al. Liver abscess due to Lactobacillus rhamnosus strain indistinguishable from L. rhamnosus strain GG. Clin Infect Dis 1999;28:1159-60.
  7. MacGregor G, Smith AJ, Thakker B, Kinsella J. Yoghurt biotherapy: contraindicated in immunosuppressed patients? Postgrad Med J 2002;78:366-7. PubMed
  8. Land MH, Rouster-Stevens K, Woods CR, et al. Lactobacillus sepsis associated with probiotic therapy. Pediatrics 2005;115:178-81.
  9. De Groote MA, Frank DN, Dowell E, et al. Lactobacillus rhamnosus GG bacteremia associated with probiotic use in a child with short gut syndrome. Pediatr Infect Dis J 2005;24:278-80. PubMed
  10. Vahabnezhad E, Mochon AB, Wozniak LJ, Ziring DA. Lactobacillus bacteremia associated with probiotic use in a pediatric patient with ulcerative colitis. J Clin Gastroenterol. 2013;47(5):437-9. PubMed
  11. Pruccoli G, Silvestro E, Pace Napoleone C, Aidala E, Garazzino S, Scolfaro C. Are probiotics safe? Bifidobacterium bacteremia in a child with severe heart failure. Infez Med. 2019;27(2):175-178.
  12. Sendil S, Shrimanker I, Mansoora Q, Goldman J, Nookala VK. Lactobacillus rhamnosus bacteremia in an immunocompromised renal transplant patient. Cureus. 2020;12(2):e6887. PubMed
  13. Albarillo FS, Shah U, Joyce C, Slade D. Lactobacillus rhamnosus Infection: A single-center 4-year descriptive analysis. J Glob Infect Dis. 2020;12(3):119-123. PubMed
  14. Pasala S, Singer L, Arshad T, Roach K. Lactobacillus endocarditis in a healthy patient with probiotic use. IDCases. 2020;22:e00915. PubMed
  15. Agrawal S, Tuchman ES, Bruce MJ, Theodorou ME. Fatal Lactobacillus endocarditis in a patient with transcatheter aortic valve replacement. BMJ Case Rep. 2020;13(11):e236835.
  16. Antoun M, Hattab Y, Akhrass FA, Hamilton LD. Uncommon pathogen, Lactobacillus, causing infective endocarditis: Case report and review. Case Rep Infect Dis. 2020;2020:8833948. PubMed
  17. Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
  18. Franko B, Vaillant M, Recule C, Vautrin E, et al. Lactobacillus paracasei endocarditis in a consumer of probiotics. Med Mal Infect. 2013;43(4):171-3. PubMed
  19. Campbell RE, Miller A, Afroze A. Native valve endocarditis secondary to Lactobacillus paracasei bacteremia. Consultant. 2020;60(9):27-8. DOI
  20. Kato K, Funabashi N, Takaoka H, et al. Lactobacillus paracasei endocarditis in a consumer of probiotics with advanced and severe bicuspid aortic valve stenosis complicated with diffuse left ventricular mid-layer fibrosis. Int J Cardiol. 2016;224:157-161. PubMed

See these in context on the Bacillus Coagulans monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring