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Dietary supplement

DNZ-2 250 mg Ingredients & Drug Interactions

by Bio-Tech Pharmacal

Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Minor
The interaction bottom line Most serious interaction: Minor

DNZ-2 250 mg is a dietary supplement by Bio-Tech Pharmacal with 1 active ingredient. Its ingredients are commonly taken for memory and focus, mood and mental clarity, adhd-type symptoms.Based on those ingredients, 219 medications have a known interaction with it, the most serious rated minor. The ingredients most likely to interact are Deanol p-Acetamidobenzoate. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of DNZ-2 250 mg by Bio-Tech Pharmacal

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • “Deanol p-Acetamidobenzoate” is listed as a grouped ingredient — the label gives one combined amount (250 mg) without saying how much of each component you get.

DNZ-2 contains one active ingredient: DMAE (dimethylaminoethanol), also known as deanol, at 250 mg per capsule. Deanol is a compound thought to increase acetylcholine, a brain chemical involved in memory and nerve function.

The capsule itself is made from gelatin.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Deanol's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: Memory, focus, and mental clarity.
  • We looked for evidence on: Attention deficit-hyperactivity disorder (ADHD), Cognitive function, Tardive dyskinesia, Brain health, Mental focus, ADHD symptoms.
  • The closest evidence on file: Deanol is rated "Likely Ineffective" for Tardive dyskinesia (Natural Medicines).
  • Also on file: Deanol is rated "Insufficient Reliable Evidence To Rate" for Attention deficit-hyperactivity disorder (ADHD), Cognitive function.

The evidence for deanol is limited. It's rated likely ineffective for Alzheimer's disease and tardive dyskinesia (a movement disorder).

For aging skin, ADHD, and athletic performance, there isn't enough reliable evidence to know whether it works. If you're considering this for one of those uses, talk with your doctor about whether the evidence supports it for your situation.

The evidence, ingredient by ingredient Deanol

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Deanol is generally well tolerated by some adults, but side effects have been reported — most commonly abdominal cramps, pain, diarrhea, drowsiness, nausea, and vomiting. At higher doses (above 1000 mg daily), it's been linked to mood changes including depression and hypomania, and in people with schizophrenia, it may worsen symptoms.

The product should be avoided during pregnancy because there isn't enough safety data, and should not be used while breastfeeding.

Side effects, ingredient by ingredient Deanol

Meds to double-check

Minor interactions only
Known Interaction Concern · database check
Minor only

Only Minor-severity interactions are documented for these ingredients.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Deanol.
  • The most serious interaction on file is rated Minor.
  • For scale: 219 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, check with your doctor or pharmacist if you're on anticholinergic drugs (such as medications for overactive bladder or certain Parkinson's symptoms) or cholinergic drugs (such as some treatments for myasthenia gravis or glaucoma). These are the medication types with documented interactions in our data.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Only minor medication interactions are documented, and safety information is well characterized.

DNZ-2 is a single-ingredient supplement with limited evidence for its claimed uses and interactions with common medications. If you take anticholinergic or cholinergic drugs, or have a history of mood disorders or schizophrenia, check with your doctor or pharmacist before starting it.

Even if you don't take those drugs, discuss it with your own healthcare provider to decide whether it's right for you.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Apr 23, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about DNZ-2 250 mg, straight from the product label.

Brand Bio-Tech Pharmacal
Barcode (UPC) 705105101903
Net contents 100 Capsule(s)
Market status On market
Date entered into DSLD Apr 23, 2020
DSLD ID 217554
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years), Halal, Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for DNZ-2 250 mg by Bio-Tech Pharmacal, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
UPC/BARCODE
705105101903
IngredientAmount% DV
DMAE83 mg--
Deanol p-Acetamidobenzoate250 mg--

Other ingredients: Gelatin Capsule

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Precautions

Keep out of the reach of children.

Safety sealed for your protection.

Storage

Store tightly closed in a cool, dry place.

Suggested/Recommended/Usage/Directions

Suggested Use: One capsule per day or as directed by a healthcare professional.

Formulation

Contains No: Dairy, egg, fish, shellfish, nuts, wheat, gluten, soy, sugar, yeast, artificial preservatives or colors.

Gluten free Non GMO

cGMP Current Good Manufacturing Practice

Formula

Halal certified.

General Statements

Energy = Health

PNR Over 100 Partners in Research

FDA Statement of Identity

Dietary Supplement

Seals/Symbols

cGMP Current Good Manufacturing Practice

ISWA Halal

Made in the USA

See for yourself

DNZ-2 250 mg by Bio-Tech Pharmacal label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in DNZ-2 250 mg by Bio-Tech Pharmacal

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Amounts shown are per serving.

Deanol p-Acetamidobenzoate

Interacts with
219 drugs
250 mg per serving

Deanol (DMAE) is a compound related to choline that is marketed for memory, focus, and mood, but solid human evidence for most of these uses is limite...

Deanol p-Acetamidobenzoate monograph & interactions

Other (inactive) ingredients: Gelatin Capsule. These complete the product’s ingredient list but are not active constituents.

Interaction report

DNZ-2 250 mg by Bio-Tech Pharmacal Drug Interactions

Want to check YOUR meds against DNZ-2 250 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
219Drugs
219 Minor

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in DNZ-2 250 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Deanol p-Acetamidobenzoate2 drug types · 219 drugs

Anticholinergic Drugs

Theoretically, deanol might decrease the effectiveness of anticholinergic drugs.
Deanol is thought to increase acetylcholine levels.

Likelihood Unlikely Evidence D
Cholinergic Drugs

Theoretically, deanol might increase the effects and adverse effects of cholinergic drugs.
Deanol is thought to increase acetylcholine levels.

Likelihood Unlikely Evidence D
The maker

Brand information

Manufacturer and brand details for DNZ-2 250 mg, from the product label.

Bio-Tech Pharmacal

See all Bio-Tech Pharmacal products
Name
Bio-Tech
City
Fayetteville
State
AR
ZipCode
72704
Phone Number
1-800-345-1199
Web Address
www.BioTechPharmacal.com
Pharmacist Counseling Corner

DNZ-2 250 mg by Bio-Tech Pharmacal: Common Questions

Does DNZ-2 250 mg by Bio-Tech Pharmacal interact with any medications?
Yes. Based on its ingredients, DNZ-2 250 mg has a known interaction with 219 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
DNZ-2 250 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take DNZ-2 if I'm pregnant or breastfeeding?
No — safety data isn't available. The facts advise against use during pregnancy and breastfeeding. Talk with your doctor or pharmacist before taking it if you're pregnant, planning to become pregnant, or nursing.
What are the most common side effects I should watch for?
The most common ones are abdominal cramps and pain, diarrhea, drowsiness, nausea, and vomiting. Deanol has also been reported to cause constipation, headache, insomnia, and mood changes in some people.
Does DNZ-2 actually work for Alzheimer's disease?
No — it's rated likely ineffective for Alzheimer's. If you're considering it for cognitive health, there are other options worth discussing with your doctor.
Is there enough evidence that deanol helps with ADHD or athletic performance?
Not in the data we hold. For both ADHD and athletic performance, the evidence is insufficient to know whether it works, so talk with your doctor about treatments with stronger evidence.
What is deanol and why is it in this supplement?
Deanol (DMAE) is a compound thought to increase acetylcholine, a brain chemical involved in memory and nerve function. It's included in supplements marketed for cognitive and skin health, though the evidence for most of those uses is limited.
Can deanol affect my mental health or mood?
Yes — at higher doses (above 1000 mg daily), it's been reported to cause mood changes including depression and hypomania. If you have a history of mood disorders or schizophrenia, deanol may worsen your symptoms, so check with your doctor first.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if DNZ-2 250 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

DNZ-2 250 mg label
Sources

Sources & How We Checked

DNZ-2 250 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 15 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Deanol 15 references
  1. Davies C, Maidment S, Hanley P, et al. Dimethylaminoethanol (DMAE). HSE. Risk assessment document; EH72/2;1997. (TOXLINE).
  2. Re O. 2-Dimethylaminoethanol (deanol): a brief review of its clinical efficacy and postulated mechanism of action. Curr Ther Res Clin Exp 1974;16:1238-42.
  3. Pieralisi G, Ripari P, Vecchiet L. Effects of a standardized ginseng extract combined with dimethylaminoethanol bitartrate, vitamins, minerals, and trace elements on physical performance during exercise. Clin Ther 1991;13:373-82.
  4. George J, Pridmore S, Aldous D. Double blind controlled trial of deanol in tardive dyskinesia. Aust N Z J Psychiatry 1981;15:68-71. PubMed
  5. Penovich P, Morgan JP, Kerzner B, et al. Double-blind evaluation of deanol in tardive dyskinesia. JAMA 1978;239:1997-8. DOI
  6. de Montigny C, Chouinard G, Annable L. Ineffectiveness of deanol in tardive dyskinesia: a placebo controlled study. Psychopharmacology (Berl) 1979;65:219-23. PubMed
  7. Lindeboom SF, Lakke JP. Deanol and physostigmine in the treatment of L-dopa-induced dyskinesias. Acta Neurol Scand 1978;58:134-8. PubMed
  8. Jus A, Villeneuve A, Gautier J, et al. Deanol, lithium and placebo in the treatment of tardive dyskinesia. A double-blind crossover study. Neuropsychobiology 1978;4:140-9. PubMed
  9. Lewis JA, Young R. Deanol and methylphenidate in minimal brain dysfunction. Clin Pharmacol Ther 1975;17:534-40. PubMed
  10. Fisman M, Mersky H, Helmes E. Double-blind trial of 2-dimethylaminoethanol in Alzheimer's disease. Am J Psychiatry 1981;138:970-2. PubMed
  11. Ferris SH, Sathananthan G, Gershon S, et al. Senile dementia: treatment with deanol. J Am Geriatr Soc 1977;25:241-4. PubMed
  12. Haug BA, Holzgraefe M. Orofacial and respiratory tardive dyskinesia: potential side effects of 2-dimethylaminoethanol (deanol)? Eur Neurol 1991;31:423-5. PubMed
  13. Casey DE. Mood alterations during deanol therapy. Psychopharmacology (Berl) 1979;62:187-91. PubMed
  14. Sergio W. Use of DMAE (2-dimethylaminoethanol) in the induction of lucid dreams. Med Hypotheses 1988;26:255-7. PubMed
  15. Osol A, Hoover JE, eds. Remington's Pharmaceutical Science, 15th ed. Easton, PA: Mack Publishing Company, 1975.

See these in context on the Deanol monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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