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Dietary supplement

Dong Quai 1,000 mg Ingredients & Drug Interactions

by Nature's Answer

Dong Quai 1,000 mg label
See full label image
Capsule Category: Botanical
Most serious interaction: Major
Clinical methodology reviewed by · Updated Oct 7, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Dong Quai 1,000 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

Dong Quai 1,000 mg is a dietary supplement by Nature's Answer with 1 active ingredient. Its ingredients are commonly taken for menopause symptoms, menstrual cramps and irregular periods, premenstrual syndrome (pms).Based on those ingredients, 163 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Angelica sinensis. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Dong Quai 1,000 mg by Nature's Answer

Ask about any prescription or over-the-counter medication and we check it for interactions with Dong Quai 1,000 mg by Nature's Answer — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Dong Quai 1,000 mg by Nature's Answer

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 23, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: Angelica sinensis (dong quai) at 1,000 mg per capsule. The remaining ingredients are cellulose, rice flour, and calcium silicate — all inactive fillers and capsule materials.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Dong Quai's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: supports female hormonal balance.
  • We looked for evidence on: Menopausal symptoms, Premenstrual syndrome (PMS), Dysmenorrhea, irregular menstruation, hormonal health.
  • The closest evidence on file: Dong Quai is rated "Insufficient Reliable Evidence To Rate" for Menopausal symptoms (Natural Medicines).
  • Also on file: Dong Quai is rated "Insufficient Reliable Evidence To Rate" for Premenstrual syndrome (PMS), Dysmenorrhea.

The evidence we hold doesn't establish that dong quai works for the uses listed — iron deficiency anemia, osteoporosis, heart disease, migraine, or eczema. All carry a rating of insufficient reliable evidence, meaning the research either hasn't happened or is too weak or thin to draw firm conclusions.

The evidence, ingredient by ingredient Dong Quai

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Orally, dong quai is generally well-tolerated; the most common side effects are burping and flatulence. It may increase bleeding risk and cause skin sensitivity to sunlight, so use with care if you're in the sun often.

The safety data advises against using it during pregnancy because it may stimulate the uterus and affect bleeding. There isn't enough safety information to recommend it while breastfeeding — talk with your doctor or pharmacist about whether it's right for you during lactation.

Side effects, ingredient by ingredient Dong Quai

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Dong Quai.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 163 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, double-check with your doctor or pharmacist if you take warfarin or any other blood thinner (anticoagulants or antiplatelets) — dong quai may raise your bleeding risk, and warfarin interactions can be serious. If you take estrogen-based medications like hormone replacement therapy, confirm it's okay to combine with dong quai.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Major medication interactions have been identified, and safety information is well characterized.

Dong quai is worth considering if you're interested in traditional herbal support, but it's not a first choice if you take blood thinners or hormone medications — the interaction risk is real. If you're pregnant or breastfeeding, the safety data says to avoid it or at least discuss it with your own doctor or pharmacist first.

Check your exact medications before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Aug 23, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Dong Quai 1,000 mg, straight from the product label.

Brand Nature's Answer
Barcode (UPC) 083000161704
Net contents 90 Vegetarian Capsule(s)
Market status On market
Date entered into DSLD Aug 23, 2023
DSLD ID 295473
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Women (not pregnant or lactating), Adult Female (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Dong Quai 1,000 mg by Nature's Answer, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
45
UPC/BARCODE
083000161704
IngredientAmount% DV
Angelica sinensis1000 mg--

Other ingredients: Cellulose, Rice Flour, Calcium Silicate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)

Nature's Answer Discover Nature's Answer And trust the difference... The true nature of our standards goes way beyond the herb...

Nature's Answer Since 1972

Copyright 2020 Nature's Answer

Precautions

Prop, 65 Warning for California Residents Warning: Consuming this product can expose you to chemicals including lead, which is known to the State of California to cause cancer and birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov/food.

Supports Female Hormonal Balance

Warning: Keep out of reach of children.

Do not use if safety seal is damaged or missing.

Do not use if you are pregnant or nursing. If you are taking any medications, planning any medical procedure or have a medical condition, consult with your healthcare practitioner before use.

Storage

Store in a cool, dry place.

Formula

K Parve (Kosher)

Supports Female Hormonal Balance

Angelica sinensis 1,000 mg per serving

Seals/Symbols

K Parve (Kosher)

Formulation

Gluten Free

Vegan

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Suggested Use: As a dietary supplement, take two (2) capsules two (2) times a day with food or water.

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Dong Quai 1,000 mg by Nature's Answer label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Dong Quai 1,000 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Dong Quai 1,000 mg by Nature's Answer

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container45 Amounts shown are per serving.

Angelica sinensis

Interacts with
163 drugs
1000 mg per serving

Dong Quai is a traditional Chinese herb often called "female ginseng" and is mostly used for menstrual and menopausal complaints. High-quality scienti...

Angelica sinensis monograph & interactions

Other (inactive) ingredients: Cellulose, Rice Flour, Calcium Silicate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Dong Quai 1,000 mg by Nature's Answer Drug Interactions

Want to check YOUR meds against Dong Quai 1,000 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
163Drugs
2 Major 161 Moderate

Ingredients driving the most interactions

Angelica sinensis 163

Individual Drug Interactions

The ingredients in Dong Quai 1,000 mg interact with 163 drugs. Click any drug to see the details.

1 of the 1 ingredient in Dong Quai 1,000 mg interact with drugs. Each result below shows which ingredient is responsible. Angelica sinensis

Each ingredient & the kinds of drugs it affects

For each ingredient in Dong Quai 1,000 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Angelica sinensis3 drug types · 163 drugs

Warfarin (Coumadin)

Dong quai may increase the risk of bleeding when used with warfarin.
Case reports suggest that concomitant use of dong quai with warfarin can increase the anticoagulant effects of warfarin and increase the risk of bleeding. In one case, after 4 weeks of taking dong quai 565 mg once or twice daily, the international normalized ratio (INR) increased to 4.9. The INR normalized 4 weeks after discontinuation of dong quai.

Likelihood Probable Evidence D
Anticoagulant/Antiplatelet Drugs

Theoretically, dong quai may increase the risk of bleeding when used with anticoagulant or antiplatelet drugs; however, research is conflicting.
Animal studies suggest that dong quai has antithrombin activity and inhibits platelet aggregation due to its coumarin components. Additionally, some case reports in humans suggest that dong quai can increase the anticoagulant effects of warfarin. However, clinical research in healthy adults shows that taking 1 gram of dong quai root daily for 3 weeks does not significantly inhibit platelet aggregation or cause bleeding. Until more is known, use dong quai with caution in patients taking antiplatelet/anticoagulant drugs.

Likelihood Possible Evidence D
Estrogens

Theoretically, dong quai may reduce the effects of estrogens.
Dong quai has estrogenic effects. Theoretically, concomitant use of large amounts of dong quai might interfere with hormone replacement therapy due to competition for estrogen receptors.

Likelihood Possible Evidence D
Angelica sinensis full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Dong Quai 1,000 mg, from the product label.

Nature's Answer

See all Nature's Answer products
Name
Nature's Answer
Street Address
85 Commerce Drive
City
Hauppauge
State
NY
ZipCode
11788
Phone Number
(800) 439-2324
Web Address
www.naturesanswer.com
Pharmacist Counseling Corner

Dong Quai 1,000 mg by Nature's Answer: Common Questions

Does Dong Quai 1,000 mg by Nature's Answer interact with any medications?
Yes. Based on its ingredients, Dong Quai 1,000 mg has a known interaction with 163 medications, including 2 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Dong Quai 1,000 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take dong quai if I'm on warfarin or another blood thinner?
No — not without checking with your doctor first. Dong quai may increase bleeding risk with warfarin and other blood thinners. Case reports show this can happen within a few weeks of starting it. Your doctor or pharmacist needs to know before you add it.
What are the most common side effects?
The most common ones are burping and flatulence. Dong quai can also make your skin more sensitive to sunlight, so be careful if you're outside a lot. Rarely, occupational exposure has triggered allergic asthma and rhinitis in some people.
Is dong quai safe during pregnancy?
No. The safety data rates it as possibly unsafe during pregnancy because it may stimulate the uterus and affect bleeding. Avoid it if you're pregnant.
Is it safe while breastfeeding?
There isn't enough safety information to know. The data advises against it while breastfeeding — talk with your doctor or pharmacist for personalized advice.
Does dong quai actually work for anemia, arthritis, or hot flashes?
The evidence we hold doesn't establish that it does. All the uses listed — anemia, osteoporosis, heart disease, migraine, and eczema — are rated as having insufficient reliable evidence, meaning the research is either missing or too weak to say for certain.
Can dong quai interfere with hormone replacement therapy?
Possibly. Dong quai has estrogenic activity, which means theoretically it could interfere with estrogen-based medications by competing for the same receptors. If you take HRT, check with your doctor or pharmacist before adding this.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Dong Quai 1,000 mg is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Dong Quai 1,000 mg label
Go deeper

The Full Monographs Behind Dong Quai 1,000 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Dong Quai

Interacts with 163 drugs

Dong Quai is a traditional Chinese herb often called "female ginseng" and is mostly used for menstrual and menopausal complaints. High-quality scientific evidence that it works for these use...

Read the full Dong Quai monograph →
Sources

Sources & How We Checked

Dong Quai 1,000 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 19 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Dong Quai 19 references
  1. Hirata JD, Swiersz LM, Zell B, et al. Does dong quai have estrogenic effects in postmenopausal women? A double-blind, placebo-controlled trial. Fertil Steril 1997;68:981-6. PubMed
  2. Page RL II, Lawrence JD. Potentiation of warfarin by dong quai. Pharmacotherapy 1999;19:870-6. PubMed
  3. Heck AM, DeWitt BA, Lukes AL. Potential interactions between alternative therapies and warfarin. Am J Health Syst Pharm 2000;57:1221-7. DOI
  4. Eagon PK, Elm MS, Hunter DS, et al. Medicinal herbs: modulation of estrogen action. Era of Hope Mtg, Dept Defense; Breast Cancer Res Prog, Atlanta, GA 2000;Jun 8-11.
  5. Dr. Duke's Phytochemical and Ethnobotanical Databases. Available at: http://www.ars-grin.gov/duke/.
  6. Amato P, Christophe S, Mellon PL. Estrogenic activity of herbs commonly used as remedies for menopausal symptoms. Menopause 2002;9:145-50. PubMed
  7. Shi M, Chang L, He G. [Stimulating action of Carthamus tinctorius L., Angelica sinensis (Oliv.) Diels and Leonurus sibiricus L. on the uterus]. Zhongguo Zhong Yao Za Zhi 1995;20:173-5, 192.
  8. Hoult JR, Paya M. Pharmacological and biochemical actions of simple coumarins: natural products with therapeutic potential. Gen Pharmacol 1996;27:713-22.. PubMed
  9. Cheong JL, Bucknall R. Retinal vein thrombosis associated with a herbal phytoestrogen preparation in a susceptible patient. Postgrad Med J 2005;81:266-7.. PubMed
  10. Chang CJ, Chiu JH, Tseng LM, et al. Modulation of HER2 expression by ferulic acid on human breast cancer MCF7 cells. Eur J Clin Invest 2006;36:588-96. PubMed
  11. Chuang CH, Doyle P, Wang JD, et al. Herbal medicines used during the first trimester and major congenital malformations: an analysis of data from a pregnancy cohort study. Drug Saf 2006;29:537-48. PubMed
  12. Lau CBS, Ho TCY, Chan TWL, Kim SCF. Use of dong quai (Angelica sinensis) to treat peri- and postmenopausal symptoms in women with breast cancer: is it appropriate? Menopause 2005;12:734-40.
  13. Ellis GR, Stephens MR. Untitled (photograph and a brief case report). BMJ 1999;319:650.
  14. Nambiar, S., Schwartz, R. H., and Constantino, A. Hypertension in mother and baby linked to ingestion of Chinese herbal medicine. West J Med 1999;171(3):152.
  15. Lee, S. K., Cho, H. K., Cho, S. H., Kim, S. S., Nahm, D. H., and Park, H. S. Occupational asthma and rhinitis caused by multiple herbal agents in a pharmacist. Ann.Allergy Asthma Immunol. 2001;86(4):469-474. PubMed
  16. Xu, J. and Li, G. [Observation on short-term effects of Angelica injection on chronic obstructive pulmonary disease patients with pulmonary hypertension]. Zhongguo Zhong Xi Yi Jie He Za Zhi 2000;20(3):187-189.
  17. Scott, G. N. and Elmer, G. W. Update on natural product--drug interactions. Am J Health Syst.Pharm 2-15-2002;59(4):339-347. PubMed
  18. Circosta, C., Pasquale, R. D., Palumbo, D. R., Samperi, S., and Occhiuto, F. Estrogenic activity of standardized extract of Angelica sinensis. Phytother.Res. 2006;20(8):665-669.
  19. Fung FY, Wong WH, Ang SK, et al. A randomized, double-blind, placebo- controlled study on the anti-haemostatic effects of Curcuma longa, Angelica sinensis and Panax ginseng. Phytomedicine. 2017;32:88-96. PubMed

See these in context on the Dong Quai monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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