Interactions on record — worth a quick check against your medications. Based on 2 of 4 ingredients. Check your meds →
Dietary supplement

Dopamite Ingredients & Drug Interactions

by MHP Maximum Human Performance

Dopamite label
See full label image
Tablet Or Pill Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Dopamite against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Dopamite is a dietary supplement by MHP Maximum Human Performance with 4 active ingredients. Its ingredients are commonly taken for treating or preventing b12 deficiency, pernicious anemia, low energy and fatigue.Based on those ingredients, 51 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Copper, Vitamin B12. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Dopamite by MHP Maximum Human Performance

Ask about any prescription or over-the-counter medication and we check it for interactions with Dopamite by MHP Maximum Human Performance — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Dopamite by MHP Maximum Human Performance

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 23, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 4 of its 4 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

Dopamite contains 4 active ingredients. Vitamin B12 supports nerve function and red blood cell formation.

Folate works alongside B12 for cell division and DNA synthesis. Copper is an essential mineral involved in energy production and collagen formation.

The product also contains DOPAMITE Dopaminergic Fat Burning Catalyst, a proprietary blend. The remaining ingredients are inactive — fillers, binders, and capsule materials like microcrystalline cellulose, stearic acid, and silica that help hold the tablet together.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Strong

Clinical evidence supports at least one of this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: weight management and dopamine support.
  • We looked for evidence on: Fatigue, Copper deficiency, Vitamin B12 deficiency, Metabolism, Food cravings, Dopamine regulation.
  • The strongest evidence on file: Vitamin B12 is rated "Effective" for Vitamin B12 deficiency (Natural Medicines).
  • Also on file: Copper is rated "Likely Effective" for Copper deficiency.
  • Also on file: Vitamin B12 is rated "Insufficient Reliable Evidence To Rate" for Fatigue.

Vitamin B12 is effective for treating B12 deficiency and certain rare genetic conditions like Imerslund-Grasbeck disease, and likely effective for cyanide poisoning. It's also possibly effective for canker sores and postherpetic neuralgia (nerve pain after shingles).

Copper is likely effective for copper deficiency, but possibly ineffective for Alzheimer's disease. For acne, chemotherapy-related anemia, and brain tumors, the evidence isn't reliable enough to rate.

The effectiveness of folate and the proprietary DOPAMITE ingredient is not detailed in our data.

The evidence, ingredient by ingredient Vitamin B12 Copper

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Vitamin B12 is generally very well tolerated — your body excretes excess B12 in urine, so there's no established upper limit. It's considered safe at normal recommended amounts during pregnancy and breastfeeding.

Allergic reactions like rash or hives are rare but possible, and may occur in people with cobalt sensitivity. A rare serious effect, hypokalemia (very low potassium levels), has been reported when B12 corrects severe anemia — symptoms would include severe weakness or irregular heartbeat.

Copper is safe in amounts found in food and standard supplements, but excess copper is toxic. It's needed in pregnancy at recommended amounts, though high-dose supplements should be avoided unless advised by your doctor.

No specific adverse effects are documented in our data for the doses typically found in supplements, though contact dermatitis from copper is rare.

Side effects, ingredient by ingredient Vitamin B12 Copper

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 2 matched ingredients can interact with medications — Copper, Vitamin B12.
  • The most serious interaction on file is rated Moderate.
  • For scale: 51 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take any medications, double-check before starting — especially penicillamine (Moderate severity), where you'd need to separate dosing by 2 hours; metformin (Minor); or oral contraceptives (Minor). We hold no interaction data for folate or the proprietary DOPAMITE ingredient, so those can't be ruled in or out from our records.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with clinical evidence supporting its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Dopamite may be worth considering if you're looking to support B12 and copper status or if you have a B12 deficiency. If you take metformin for diabetes, penicillamine for a joint or connective tissue condition, or birth control pills, talk with your doctor or pharmacist before starting — the interactions are documented and manageable with timing or monitoring.

Your healthcare provider or pharmacist can help you decide if this product fits your situation.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Mar 25, 2013.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Dopamite, straight from the product label.

Brand MHP Maximum Human Performance
Barcode (UPC) 666222091679
Net contents 72 Tablet(s)
Market status On market
Date entered into DSLD Mar 25, 2013
DSLD ID 19295
Product type Other Combinations
Supplement form Tablet Or Pill
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Dopamite by MHP Maximum Human Performance, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Tablet(s)
Maximum serving Sizes:
2 Tablet(s)
Servings per container
72
UPC/BARCODE
666222091679
IngredientAmount% DV
Vitamin B12100 mcg1667%
Folate125 mcg31%
Copper1 mg50%
DOPAMITE Dopaminergic Fat Burning Catalyst540 mg--

Other ingredients: Calcium Carbonate, Microcrystalline Cellulose, Stearic Acid, Croscarmellose Sodium, Crospovidone, Sodium Starch Glycolate, Hypromellose, Magnesium Stearate, Silica, Hydroxypropyl Cellulose, Titanium Dioxide, Polyethylene Glycol, Propylene Glycol, Yellow 5 Lake, Yellow 6 Lake

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Precautions

WARNING: Consult a physician before use. Do not use if you have high blood pressure, heart problems or are contemplating becoming pregnant.

- Keep out of reach of children.

- Do not purchase if seal is broken.

General Statements

DOPAMINERGIC FAT BURNING CATALYST* DOPAMITE belongs to a new class of weight management aids known as dopaminergics. Frequent cravings, low energy and a sluggish metabolism may all be associated with low levels of dopamine. Dopamine is a potent neurotransmitter and the driving force of your brain's reward, pleasure and motivation system, also known as "the fat burning control center."* DOPAMITE helps catalyze fat burning by supporting maximum healthy levels of dopamine and dopamine-dependent (dopaminergic) functions, as well as the functions of the supporting neurotransmitters serotonin, epinephrine (adrenaline) and norepinephrine. All 4 play powerful roles in regulating energy, motivation, satiety (a reduction in hunger after eating) and well-being.* DOPAMITE's powerful effects are driven by a scientifically engineered blend of actives including highly standardized botanical extracts that have been carefully assessed for potency and efficacy. DOPAMITE should only be used by healthy adults who are seeking to achieve significant weight loss.*

Activates Fat Burning Control Center* EXPLOTECH FAST RELEASE TECHONOLOGY

BONUS SIZE 20% MORE FREE!

GSN####

General

MHP000-06/12

Storage

- Store at 15(0)-30(0)C (59(0)-86(0)F). - Protect from heat, light and moisture.

FDA Statement of Identity

Dietary Supplement

FDA Disclaimer Statement

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Suggested/Recommended/Usage/Directions

Directions: Please read entire label and directions before taking. DOPAMITE is a powerful dopaminergic and dose should be based upon your individual tolerance. Begin by taking one tablet daily to assess tolerance. If one tablet dose is well tolerated, you may increase the dose to two tablets once daily. Preferably take in the morning or early afternoon. Do not exceed two tablets daily.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Dopamite by MHP Maximum Human Performance label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Dopamite label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Dopamite by MHP Maximum Human Performance

These are the 4 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Tablet(s) Dosage formTablet Or Pill Servings per container72 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Vitamin B12

Interacts with
20 drugs
100 mcg per serving Form: Cyanocobalamin

Vitamin B12 (cobalamin) is an essential nutrient your body needs to make red blood cells, keep nerves healthy, and support DNA. Supplements are very h...

Vitamin B12 monograph & interactions

Folate

125 mcg per serving Form: Folic Acid

Copper

Interacts with
31 drugs
1 mg per serving Form: Copper Gluconate

Copper is an essential trace mineral your body needs in small amounts for making red blood cells, supporting nerves and bones, and helping enzymes wor...

Copper monograph & interactions

DOPAMITE Dopaminergic Fat Burning Catalyst

540 mg per serving Form: 5-HTP, Caffeine, DL-Phenylalanine, Ilex paraguariensis leaf extract, Mucuna pruriens seed extract, N-Acetyl L-Tyrosine, Theobromine, Vinpocetine

Other (inactive) ingredients: Calcium Carbonate, Microcrystalline Cellulose, Stearic Acid, Croscarmellose Sodium, Crospovidone, Sodium Starch Glycolate, Hypromellose, Magnesium Stearate, Silica, Hydroxypropyl Cellulose, Titanium Dioxide, Polyethylene Glycol, Propylene Glycol, Yellow 5 Lake, Yellow 6 Lake. These complete the product’s ingredient list but are not active constituents.

Interaction report

Dopamite by MHP Maximum Human Performance Drug Interactions

Want to check YOUR meds against Dopamite?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
51Drugs
1 Moderate 50 Minor

Ingredients driving the most interactions

Copper 31
Vitamin B12 20

Individual Drug Interactions

The ingredients in Dopamite interact with 51 drugs. Click any drug to see the details.

2 of the 4 ingredients in Dopamite interact with drugs. Each result below shows which ingredient is responsible. Copper Vitamin B12

Each ingredient & the kinds of drugs it affects

For each ingredient in Dopamite with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Copper2 drug types · 31 drugs

Penicillamine (Cuprimine, Depen)

Theoretically, taking copper with penicillamine might decrease the absorption of penicillamine; separate dosing by at least 2 hours.
Copper chelates penicillamine, which decreases its absorption and may reduce its clinical effects.

Likelihood Probable Evidence D
Contraceptive Drugs

Theoretically, taking copper with contraceptive drugs might increase the levels and toxic effects of copper.
A meta-analysis of clinical studies suggests that chronic use of oral contraceptives increases serum copper levels by a mean of 57 mcg/dL. In most people, this resulted in levels above the normal reference range for copper.

Likelihood Possible Evidence D
Copper full monograph & interactions

Vitamin B121 drug type · 20 drugs

Metformin (Glucophage)

Metformin, a common medication used to manage type 2 diabetes, has been associated with lower vitamin B12 levels in some individuals. Prolonged use of metformin can interfere with the absorption of B12 in the digestive system, potentially leading to a deficiency in this essential vitamin.

Likelihood Possible Evidence A
Vitamin B12 full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Dopamite, from the product label.

MHP Maximum Human Performance

See all MHP Maximum Human Performance products
Name
Maximum Human Performance, LLC
Street Address
21 Dwight Place
City
Fairfield
State
NJ
ZipCode
07004
Phone Number
1.888.783.8844
Web Address
www.MHPSTRONG.com
Pharmacist Counseling Corner

Dopamite by MHP Maximum Human Performance: Common Questions

Does Dopamite by MHP Maximum Human Performance interact with any medications?
Yes. Based on its ingredients, Dopamite has a known interaction with 51 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Dopamite contains 4 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is B12 safe during pregnancy and breastfeeding?
Yes. Vitamin B12 is considered likely safe at normal recommended amounts during both pregnancy and breastfeeding, and it's actually needed at these times. Follow your provider's dosing advice.
Can I take this if I'm on birth control?
The copper in this product may raise copper levels slightly if you're on oral contraceptives — some studies show levels can go higher than normal. Talk with your doctor or pharmacist before adding it to see if monitoring is needed.
What are the side effects of B12 in this product?
Taken orally, B12 is generally well tolerated. Allergic reactions like rash or itching are rare but possible, especially if you're sensitive to cobalt. Serious side effects are very uncommon.
Is copper safe in this supplement?
Yes, in the amounts found in standard supplements. Copper is essential for your body, but excess copper can be toxic — stick to recommended doses and avoid very high-dose supplements unless your doctor advises it.
What is DOPAMITE?
It's listed as the product's proprietary dopaminergic fat-burning catalyst, but the specific ingredients and amounts in that blend aren't detailed in the information we hold.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Dopamite is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Dopamite label
Go deeper

The Full Monographs Behind Dopamite’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Vitamin B12

Interacts with 20 drugs

Vitamin B12 (cobalamin) is an essential nutrient your body needs to make red blood cells, keep nerves healthy, and support DNA. Supplements are very helpful for people who are deficient — su...

Read the full Vitamin B12 monograph → Herb & supplement monograph

Copper

Interacts with 31 drugs

Copper is an essential trace mineral your body needs in small amounts for making red blood cells, supporting nerves and bones, and helping enzymes work. Most people get enough copper from fo...

Read the full Copper monograph →
Sources

Sources & How We Checked

Dopamite's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 41 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Vitamin B12 30 references
  1. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline (2000). Washington, DC: National Academy Press, 2000. Available at: http://b
  2. Hartman TJ, Woodson K, Stolzenberg-Solomon R, et al. Association of the B-vitamins pyridoxal 5'-phosphate (B6), B12, and folate with lung cancer risk in older men. Am J Epidemiol 2001;153:688-94.. DOI
  3. Jansen T, Romiti R, Kreuter A, Altmeyer P. Rosacea fulminans triggered by high-dose vitamins B6 and B12. J Eur Acad Dermatol Venereol 2001;15:484-5..
  4. Lange H, Suryapranata H, De Luca G, et al. Folate therapy and in-stent restenosis after coronary stenting. N Engl J Med 2004;350:2673-81. PubMed
  5. Collin, S. M., Metcalfe, C., Refsum, H., Lewis, S. J., Zuccolo, L., Smith, G. D., Chen, L., Harris, R., Davis, M., Marsden, G., Johnston, C., Lane, J. A., Ebbing, M., Bonaa, K. H., Nygard, O., Ueland, P. M., Grau, M. V., Baron, J. A., Donovan, J. L., Nea
  6. Geissbuhler, P., Mermillod, B., and Rapin, C. H. Elevated serum vitamin B12 levels associated with CRP as a predictive factor of mortality in palliative care cancer patients: a prospective study over five years. J.Pain Symptom.Manage. 2000;20(2):93-103. PubMed
  7. Salles, N., Herrmann, F., Sakbani, K., Rapin, C. H., and Sieber, C. High vitamin B12 level: a strong predictor of mortality in elderly inpatients. J Am Geriatr.Soc 2005;53(5):917-918.
  8. Looker, H. C., Fagot-Campagna, A., Gunter, E. W., Pfeiffer, C. M., Sievers, M. L., Bennett, P. H., Nelson, R. G., Hanson, R. L., and Knowler, W. C. Homocysteine and vitamin B(12) concentrations and mortality rates in type 2 diabetes. Diabetes Metab Res R
  9. Uhl, W., Nolting, A., Golor, G., Rost, K. L., and Kovar, A. Safety of hydroxocobalamin in healthy volunteers in a randomized, placebo-controlled study. Clin Toxicol (Phila) 2006;44 Suppl 1:17-28. PubMed
  10. Borron, S. W., Baud, F. J., Barriot, P., Imbert, M., and Bismuth, C. Prospective study of hydroxocobalamin for acute cyanide poisoning in smoke inhalation. Ann Emerg.Med 2007;49(6):794-801, 801. PubMed
  11. Borron, S. W., Baud, F. J., Megarbane, B., and Bismuth, C. Hydroxocobalamin for severe acute cyanide poisoning by ingestion or inhalation. Am J Emerg.Med 2007;25(5):551-558. PubMed
  12. Lewis, J. G. Gout, Steatorrhoea, and Megaloblastic Anaemia. Ann Rheum.Dis 1962;21(3):284-286. PubMed
  13. Tal, S., Shavit, Y., Stern, F., and Malnick, S. Association between vitamin B12 levels and mortality in hospitalized older adults. J Am Geriatr.Soc 2010;58(3):523-526. PubMed
  14. Baztan, J. J., Gavidia, J. J., Gomez-Pavon, J., Esteve, A., and Ruiperez, I. High vitamin B12 levels and in-hospital mortality. J Am Geriatr.Soc 2010;58(11):2237-2238. PubMed
  15. Omboni, E., Checchini, M., and Longoni, F. [Hypopotassemia and megaloblastic anemia. Presentation of a case]. Minerva Med 8-31-1987;78(16):1255-1257.
  16. Aalfs As, Scholvinck LH, Horvath B. Acneiform eruption in a 5-year old due to vitamin B12 supplementation. Eur J Dermatol 2013;23(5):726-7. PubMed
  17. Balta I, Ozuguz P. Vitamin B12-induced acneiform eruption. Cutan Ocul Toxicol 2014;33(2):94-5. PubMed
  18. Carman KB, Belgemen T, Yis U. Involuntary movements misdiagnosed as seizure during vitamin B12 treatment. Pediatr Emerg Care 2013;29(11):1223-4. PubMed
  19. Djuric V, Bogic M, Popadic AP, et al. Anaphylactic reaction to hydroxycobalamin with tolerance to cyanocobalamin. Ann Allergy Asthma Immunol 2012;108(3):207-8. PubMed
  20. Kartel O, Gulec M, Demirel F, et al. Vitamin B12 allergy and successful desensitization with cyanocobalamin: A case report. Allergol Immunopath (Madr) 2012;40(5):324-5.
  21. Patiroglu T, Unal E, Yildirim S. Infantile tremor syndrome associated with cobalamin therapy: A case report. Clin Neurol Neurosurg 2013;115(9):1903-5. PubMed
  22. Schulte S, Barkema LW, Kardaun SH. Long-lasting atypical acneiform eruption with prominent comedones induced by hydroxocobalamin (vitamin B12). J Dtsch Dermatol Ges 2014;12(6):502-3.
  23. Zanus C, Alberini E, Costa P, et al. Involuntary movements after correction of vitamin B12 deficiency: A video-case report. Epileptic Disord 2012;14(2):174-80. PubMed
  24. Fanidi A, Carreras-Torres R, Larose TL, et al. Is high vitamin B12 status a cause of lung cancer? Int J Cancer. 2019 Sep 15;145(6):1499-1503. PubMed
  25. Fujita Y, Mizukami T, Maya Y, et al. Vitamin B12 allergy manifesting as lymphomatoid contact dermatitis. Eur J Dermatol. 2020;30(3):304-305. PubMed
  26. Dépret F, Hoffmann C, Daoud L, et al. Association between hydroxocobalamin administration and acute kidney injury after smoke inhalation: a multicenter retrospective study. Crit Care. 2019;23(1):421. PubMed
  27. Khairan P, Sobue T, Eshak ES, et al. Association of dietary intakes of vitamin B12, vitamin B6, folate, and methionine with the risk of esophageal cancer: the Japan Public Health Center-based (JPHC) prospective study. BMC Cancer 2021;21(1):982. PubMed
  28. Evans J, Pandya A, Ding Y, Qunibi WY. Hydroxocobalamin-Induced Oxalate Nephropathy in a Patient With Smoke Inhalation. Kidney Int Rep 2021;6(8):2228-2231. PubMed
  29. Lacombe V, Chabrun F, Lacout C, et al. Persistent elevation of plasma vitamin B12 is strongly associated with solid cancer. Sci Rep 2021;11(1):13361. PubMed
  30. Pegalajar-García MD, Cebolla-Verdugo M, Prados-Carmona Á, Llamas-Segura C, Navarro-Triviño FJ. Systemic allergic dermatitis to cobalt present in cyanocobalamin supplementation. Contact Dermatitis 2023;89(3):203-205. PubMed

See these in context on the Vitamin B12 monograph →

Copper 11 references
  1. Murry JJ, Healy MD. Drug-mineral interactions: a new responsibility for the hospital dietician. J Am Diet Assoc 1991;91:66-73.
  2. Campbell IA, Elmes PC. Ethambutol and the eye: zinc and copper (letter). Lancet 1975;2:711. DOI
  3. Segal S, Kaminski S. Drug-nutrient interactions. American Druggist 1996 Jul;42-8.
  4. Kozak SF, Inderlied CB, Hsu HY, et al. The role of copper on ethambutol's antimicrobial action and implications for ethambutol-induced optic neuropathy. Diag Microbiol Infect Dis 1998;30:83-7. PubMed
  5. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, DC: National Academy Press, 2002.
  6. Cantilena LR, Klaassen CD. The effect of chelating agents on the excretion of endogenous metals. Toxicol Appl Pharmacol 1982;63:344-50.
  7. Babic Z, Tariba B, Kovacic J, Pizent A, Varnai VM, Macan J. Relevance of serum copper elevation induced by oral contraceptives: a meta-analysis. Contraception. 2013 Jun;87(6):790-800. PubMed
  8. Qui Q, Zhang F, Zhu W, Wu J, Liang M. Copper in diabetes mellitus: a meta-analysis and systematic review of plasma and serum studies. Biol Trace Elem Res 2017;177(1):53-63.
  9. Walker-Smith PK, Keith DJ, Kennedy CT, Sansom JE. Allergic contact dermatitis caused by copper. Contact Dermatitis 2016;75(3):186-7. PubMed
  10. Gallentine A. Third-degree burn on the neuropathic lower extremity in a patient with diabetes while wearing a copper-containing compression sock: a case report. Wound Manag Prev 2021;67(12):26-29. DOI
  11. Chung KJ, Chin YM, Wong MS, Sanmugam A, Singaravel S, Nah SA. Effectiveness of table salt versus copper sulphate in treating umbilical granuloma: A pilot randomized controlled trial. J Pediatr Surg 2022;57(2):261-265. PubMed

See these in context on the Copper monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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