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Dietary supplement

Elderberry 500 mg Ingredients & Drug Interactions

by LuckyHerbs

Elderberry 500 mg label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Elderberry 500 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Elderberry 500 mg is a dietary supplement by LuckyHerbs with 1 active ingredient. Its ingredients are commonly taken for colds, flu (influenza), other respiratory infections.Based on those ingredients, 121 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Elderberry Concentrate. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Elderberry 500 mg by LuckyHerbs

Ask about any prescription or over-the-counter medication and we check it for interactions with Elderberry 500 mg by LuckyHerbs — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Elderberry 500 mg by LuckyHerbs

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 23, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: elderberry concentrate at 500 mg per capsule. Elderberry is a plant extract made from the ripe fruit of the elderberry shrub.

The capsule itself is made of hypromellose (a plant-based capsule material), with silicon dioxide and stearic acid added as inactive ingredients to help form and stabilize the capsule.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Elderberry product and its label doesn't state a use — see Elderberry's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence for elderberry's effectiveness isn't established in the data we hold. For conditions like hay fever, heart health, chronic fatigue, COPD, memory and thinking, and respiratory infections, the available studies don't provide reliable enough evidence to say whether it works.

The evidence, ingredient by ingredient Elderberry

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Properly cooked or prepared elderberry products are generally well tolerated. Raw or unripe elderberries, and the seeds, leaves, and bark of the elder plant, can be toxic — they contain compounds that cause nausea, vomiting, severe diarrhea, weakness, dizziness, and in serious cases, numbness and confusion.

Cooking eliminates this toxin, so as long as you're using a properly prepared supplement like this one, that risk doesn't apply. There isn't enough safety data to recommend elderberry during pregnancy or while breastfeeding.

Talk with your doctor or pharmacist about whether this product is right for you if you're pregnant, planning to become pregnant, or nursing. One case report linked elderberry use to autoimmune liver inflammation in a person with an underlying autoimmune condition, though this is rare.

Side effects, ingredient by ingredient Elderberry

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Elderberry.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: immunosuppressants / transplant drugs.
  • For scale: 121 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Double-check this product before taking it if you're on immunosuppressants (medications that intentionally weaken your immune system for transplants, autoimmune diseases, or severe inflammation) or pazopanib (a cancer medication). Both carry a Moderate-severity interaction risk.

Use the medication search tool on this page to check your exact medications, or ask your doctor or pharmacist.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Elderberry 500 mg may be worth considering if you're interested in supporting general wellness, but we don't have solid evidence it works for specific conditions. If you take any immunosuppressant medications or pazopanib, this isn't the product for you without checking with your doctor or pharmacist first.

Pregnant or breastfeeding? Talk it over with your healthcare provider before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Mar 22, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Elderberry 500 mg, straight from the product label.

Brand LuckyHerbs
Barcode (UPC) 810026421426
Net contents 120 Veg Capsule(s)
Market status On market
Date entered into DSLD Mar 22, 2023
DSLD ID 283175
Product type Botanical
Supplement form Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Elderberry 500 mg by LuckyHerbs, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Veg Capsule(s)
Maximum serving Sizes:
1 Veg Capsule(s)
Servings per container
120
UPC/BARCODE
810026421426
IngredientAmount% DV
Elderberry Concentrate500 mg--

Other ingredients: Hypromellose, Silicon Dioxide, Stearic Acid

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested Usage: Take 1 capsule 2 to 3 times daily.

Formula

Elderberry (Sambucus nigra) is a multipurpose fruit used widely throughout Europe. As a centuries-old tradition, it has been used by herbalists as a tonic to maintain health and well-being. More recently, elderberry has been recognized for its high nutritive value, especially for its potent free radical scavenging vitamins and anthocyanins. It is truly among nature's sweet and healthy surprises.

Elderberry 500 mg 10:1 Concentrate

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Precautions

Caution: For adults only.

Consult physician if pregnant/nursing, taking medication, or have a medical condition.

Keep out of reach of children.

Not manufactured with yeast, gluten, soy, corn, milk, egg, fish, shellfish or tree nut ingredients. Produced in a GMP facility that processes other ingredients containing these allergens.

General Statements

1 Year Happiness Guarantee

Formulation

Vegan

Free Radical Scavanger

Not manufactured with yeast, wheat, gluten, soy, milk, egg, fish, shellfish or tree nut ingredients.

Natural color variation may occur in this product.

Non-GMO

Seals/Symbols

Guaranteed Quality & Potency

Brand IP Statement(s)

Lucky Herbs Herbal Supplements by Lucky Vitamin

FDA Statement of Identity

Dietary Supplement

Storage

Store in a cool, dry place after opening.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Elderberry 500 mg by LuckyHerbs label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Elderberry 500 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Elderberry 500 mg by LuckyHerbs

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Veg Capsule(s) Dosage formCapsule Servings per container120 Amounts shown are per serving.

Elderberry Concentrate

Interacts with
121 drugs
500 mg per serving Form: Sambucus nigra

Elderberry is a popular herbal supplement, mainly taken to help with colds and flu. Some small studies suggest it may modestly shorten cold or flu sym...

Elderberry Concentrate monograph & interactions

Other (inactive) ingredients: Hypromellose, Silicon Dioxide, Stearic Acid. These complete the product’s ingredient list but are not active constituents.

Interaction report

Elderberry 500 mg by LuckyHerbs Drug Interactions

Want to check YOUR meds against Elderberry 500 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
121Drugs
121 Moderate

Ingredients driving the most interactions

Elderberry Concentrate 121

Individual Drug Interactions

The ingredients in Elderberry 500 mg interact with 121 drugs. Click any drug to see the details.

1 of the 1 ingredient in Elderberry 500 mg interact with drugs. Each result below shows which ingredient is responsible. Elderberry Concentrate

Each ingredient & the kinds of drugs it affects

For each ingredient in Elderberry 500 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Elderberry Concentrate2 drug types · 121 drugs

Immunosuppressants

Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Elderberry has immunostimulant activity, increasing the production of cytokines, including interleukin and tumor necrosis factor.

Likelihood Possible Evidence B
Pazopanib (Votrient)

Theoretically, elderberry might interact with pazopanib, potentially increasing the risk of adverse effects.
In one case, a 65-year-old patient taking pazopanib for 4 weeks for soft-tissue sarcoma developed severe nausea, loose stools, and elevated alanine transaminase and aspartate transaminase levels and was diagnosed with grade 3 liver injury. The patient reported taking elderberry supplements for 2 years, dose unspecified, and was also taking a multivitamin and a calcium supplement. The patient's symptoms and liver enzyme levels improved upon discontinuation of pazopanib and all supplements. Pazopanib treatment was re-initiated, at a lower dose, with no further evidence of liver injury. It was unclear in this case report if the elderberry supplements were derived from the berry, the flower, or the combination.

Likelihood Possible Evidence D
Elderberry Concentrate full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Elderberry 500 mg, from the product label.

LuckyHerbs

See all LuckyHerbs products
Name
Lucky Health Group Inc.
City
Conshohocken
State
PA
ZipCode
19428
Phone Number
1-888-635-0474
Web Address
www.LuckyVitamin.com
Pharmacist Counseling Corner

Elderberry 500 mg by LuckyHerbs: Common Questions

Does Elderberry 500 mg by LuckyHerbs interact with any medications?
Yes. Based on its ingredients, Elderberry 500 mg has a known interaction with 121 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Elderberry 500 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is elderberry safe when I'm pregnant or breastfeeding?
There isn't enough safety information to say either way. The data advises against using elderberry supplements during pregnancy and while breastfeeding. Talk with your doctor or pharmacist about whether it's right for you in these situations.
What's the difference between this supplement and raw elderberries from the store?
This is a properly prepared extract from ripe fruit, which is safe. Raw or unripe elderberries, and parts like seeds and leaves, contain toxins that cooking destroys — so raw elderberries can cause nausea, vomiting, and severe diarrhea. This product sidesteps that risk.
Will elderberry help with cold symptoms or the flu?
Elderberry is often marketed for respiratory infections, but the reliable evidence we have doesn't support that claim. You'd be taking it more on theory than proven benefit.
Can I take this if I have an autoimmune disease?
One case report described autoimmune liver inflammation in someone with an existing autoimmune condition who took elderberry long-term. Even so, this is rare. Talk with your doctor or pharmacist to see if it's safe for your situation.
What are the main side effects?
Properly prepared elderberry is generally well tolerated, and side effects are uncommon. The risk comes from raw or unripe berries or other plant parts, which can cause nausea, vomiting, and diarrhea — but this product is made from ripe fruit, so that's not a concern with it.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Elderberry 500 mg label
Go deeper

The Full Monographs Behind Elderberry 500 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Elderberry

Interacts with 121 drugs

Elderberry is a popular herbal supplement, mainly taken to help with colds and flu. Some small studies suggest it may modestly shorten cold or flu symptoms, but the evidence is limited and n...

Read the full Elderberry monograph →
Sources

Sources & How We Checked

Elderberry 500 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 6 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Elderberry 6 references
  1. Barak V, Halperin T, Kalickman I. The effect of Sambucol, a black elderberry-based, natural product, on the production of human cytokines: I. Inflammatory cytokines. Eur Cytokine Netw 2001;12:290-6..
  2. Elderberry (Sambucus species). The Poison Plant Patch, Novia Scotia Museum, 2007. Available at: http://museum.gov.ns.ca/poison/?section=species&id=117 (Accessed 16 October 2009).
  3. European elder. Canadian Poisonous Plants Information System. Available at: http://www.cbif.gc.ca/pls/pp/ppack.jump?p_null=all&p_psn=121&p_type=all&p_sci=comm&p_x=px (Accessed 16 October 2009).
  4. Raus K, Pleschka S, Klein P, Schoop R, Fisher P. Effect of an echinacea-based hot drink versus oseltamivir in Influenza treatment: a randomized, double-blind, double-dummy, multicenter, noninferiority clinical trial. . Curr Ther Res Clin Exp. 2015;20;77:6 PubMed
  5. Ramachandran A, Antala D, Pudasainee P, Panginikkod S, Gupta H. A Plausible Association Between the Use of Elderberry and Autoimmune Hepatitis. Cureus 2022;14(4):e24250. PubMed
  6. Agarwal N, Mangla A. Elderberry interaction with pazopanib in a patient with soft-tissue sarcoma: A case report and literature review. Mol Clin Oncol 2024;20(5):36. PubMed

See these in context on the Elderberry monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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