Major interaction on record — check this product against your medications before combining. Check your meds →
Dietary supplement

Ergonine Flavorless Ingredients & Drug Interactions

by PEScience

Ergonine Flavorless label
See full label image
Powder Category: Other Combinations
Most serious interaction: Major
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Ergonine Flavorless against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

Ergonine Flavorless is a dietary supplement by PEScience with 7 active ingredients. Its ingredients are commonly taken for high homocysteine levels, liver health (fatty liver), exercise performance and strength.Based on those ingredients, 455 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Calcium, L-Carnitine-L-Tartrate. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Ergonine Flavorless by PEScience

Ask about any prescription or over-the-counter medication and we check it for interactions with Ergonine Flavorless by PEScience — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
Prefer a human? Send your question to our licensed pharmacists — free, answered by email within 24 hours.

HelloPharmacist Scorecard of Ergonine Flavorless by PEScience

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 23, 2026

What’s inside

Partial disclosure
Ingredient Transparency · database check
Partial

Most active ingredients list an amount, but at least one is hidden in a blend or missing.

Why this rating?
  • The label discloses an exact amount for 6 of its 11 active ingredients.
  • “Betaine Anhydrous” is listed as a grouped ingredient — the label gives one combined amount (2,500 mg) without saying how much of each component you get.

Ergonine Flavorless is a powder with 11 ingredients, of which several are active amino acids and nutrients: L-glutamine and L-alanine (amino acids), choline bitartrate and betaine anhydrous (compounds supporting cellular function), L-carnitine-L-tartrate (a form of carnitine), calcium, and creatine anhydrous, plus herbal and proprietary blends including asafoetida root extract and glycerol. The product also contains silicon dioxide as an inactive ingredient.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: athletic performance and muscle strength support.
  • We looked for evidence on: Athletic performance, muscle recovery, exercise endurance, strength training.
  • The strongest evidence on file: Glycerol is rated "Possibly Effective" for Athletic performance (Natural Medicines).
  • Also on file: Creatine is rated "Possibly Effective" for Athletic performance.
  • Also on file: Choline is rated "Possibly Ineffective" for Athletic performance.

The evidence for effectiveness varies widely by ingredient and purpose. L-glutamine is effective for sickle cell disease and possibly effective for HIV/AIDS-related wasting, postoperative recovery, and critical illness.

L-carnitine is effective for carnitine deficiency and possibly effective for high cholesterol and heart failure. Calcium is effective for kidney failure, low blood calcium (hypocalcemia), and high potassium (hyperkalemia), and likely effective for osteoporosis.

Creatine is possibly effective for muscle strength and athletic performance. For L-alanine, choline, glycerol, and asafoetida, the evidence in our data is either insufficient or not established for most claimed uses.

The evidence, ingredient by ingredient Betaine Anhydrous Glutamine Alpha-alanine Choline Glycerol Asafoetida L-carnitine Calcium

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 7 of the 8 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 8 of 8.
  • General safety write-ups exist for 8 of 8.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Most ingredients in this product are generally well tolerated at typical doses. L-glutamine, L-alanine, choline, L-carnitine, creatine, and glycerol can all cause mild gastrointestinal side effects—bloating, diarrhea, nausea, and gas—at higher doses.

L-carnitine and creatine may also cause a fishy body odor and water retention respectively. Rare serious side effects (seizures with L-carnitine, kidney issues with creatine) have been reported.

Asafoetida in large amounts has caused headache, flatulence, and in infants a serious blood condition called methemoglobinemia. For pregnancy and lactation: L-glutamine, L-alanine, choline, and calcium are rated likely safe; L-carnitine is possibly safe during lactation but pregnancy safety data are not on file; creatine should be avoided during both pregnancy and breastfeeding; asafoetida is rated likely unsafe during pregnancy and unsafe during lactation.

Safety data for TruGlutamine Blend, Hydroxy-Isocaproic Acid, and PerfomaLean Blend during pregnancy and breastfeeding are not on file.

Side effects, ingredient by ingredient Betaine Anhydrous Glutamine Alpha-alanine Choline Glycerol Asafoetida L-carnitine Calcium

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 5 of the 8 matched ingredients can interact with medications — Asafoetida, Choline, Calcium, Glutamine, L-carnitine.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; seizure medications; heart-rhythm medications; lithium.
  • For scale: 455 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, check with your doctor or pharmacist if you take any of the following: HIV integrase inhibitors (dolutegravir or elvitegravir)—calcium can reduce their levels significantly; the antibiotic ceftriaxone given by IV—intravenous calcium can cause dangerous precipitation; blood thinners or antiplatelet drugs (warfarin, acenocoumarol, aspirin, ibuprofen, clopidogrel)—L-carnitine and asafoetida may increase bleeding risk; thyroid hormone replacement (levothyroxine)—calcium and L-carnitine can reduce its effectiveness; anticonvulsants—L-glutamine may theoretically work against seizure control; or blood pressure medications—asafoetida may add to their effects.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glancePartially disclosed formula with some supporting evidence for its stated purpose. Major medication interactions have been identified, and safety information is well characterized.

Ergonine Flavorless may be worth considering if you're looking to support muscle recovery, athletic performance, or general amino acid intake, and you don't take blood thinners, thyroid medication, certain HIV integrase inhibitors, anticonvulsants, or blood pressure medications. Because calcium in this product can significantly reduce the effectiveness of several common drugs, it's essential to check your exact medications with your doctor or pharmacist before starting.

If you're pregnant, planning pregnancy, or breastfeeding, talk with your healthcare provider—some ingredients should be avoided.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 8 of 11 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Mar 24, 2016.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Ergonine Flavorless, straight from the product label.

Brand PEScience
Barcode (UPC) 040232199448
Net contents 14 oz.; 396 Gram(s)
Market status On market
Date entered into DSLD Mar 24, 2016
DSLD ID 57482
Product type Other Combinations
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Ergonine Flavorless by PEScience, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
13.2 Gram(s)
Maximum serving Sizes:
13.2 Gram(s)
Servings per container
30
UPC/BARCODE
040232199448
IngredientAmount% DV
L-Glutamine0 NP--
L-Alanine0 NP--
Choline Bitartrate0 NP--
Betaine Anhydrous2500 mg--
L-Carnitine-L-Tartrate2000 mg--
Calcium220 mg22%
Creatine Anhydrous3000 mg--
TruGlutamine Blend2500 mg--
Hydroxy-Isocaproic Acid1500 mg--
PerfomaLean Blend1100 mg--
Glycerol0 NP--
Ferula asafoetida (root) extract0 NP--

Other ingredients: Silicon Dioxide

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Ergonine is a scientifically formulated blend of powerful ingredients designed to bring every athlete, bodybuilder, and physique enthusiast to the next level. Ergonine offers high amounts of quality ingredients, along with new blends and research to the sports industry. This formula is not based on theory or hype... it is based on existing research. Why has a product like this never made it to the market before? For starters, because no other company formulates for the consumer and to the level of PEScience. Additionally, this product is impossible for the mass-marketers of the industry to produce at a cost that is reasonable to the consumer. But PEScience puts their money into quality and formula, not marketing and gimmicks. Enjoy the science.

Claims based on ingredient studied in healthy adults when combined with exercise

30 Servings 9 Powerful Ingredients 1 All-Inclusive Formula

All-In-One-Staple Formulated from science ~ Supports lean body mass ~ Supports recovery

Suggested/Recommended/Usage/Directions

Directions: Drink 1 scoop daily mixed with 10-12 oz water. On training days, take 30- 60 minutes prior to training. On non-training days, take in the morning. Product can be taken with or without food. Shake well with water before drinking.

Shake tub before each use.

Precautions

WARNING: Do not use if pregnant or nursing.

This product is only intended for healthy adults,18 years of age or older.

Before using this product consult with your physician if you are using any prescription or over the counter medication or if you have or suspect you have any pre-existing medical condition including but not limited to: high or low blood pressure, cardiac arrhythmia, stroke, heart, liver kidney or thyroid disease, enlargement or if you are taking a MAOI (Monoamine Oxidase Inhibitor) or any other medication.

Discontinue use and consult your health care professional if you experience any adverse reaction to this product.

Do not take if pregnant or nursing.

Discontinue use 2 weeks prior to surgery. Do not use if safety seal is broken or missing

Keep out of reach of children.

Storage

Store in a cool dry place.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Formula

~ With TruCreatine, Betaine, TruGlutamin, HICA & more!

FDA Statement of Identity

Dietary Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Ergonine Flavorless by PEScience label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Ergonine Flavorless label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Ergonine Flavorless by PEScience

These are the 7 active ingredients this product is made of. Select any to open its full monograph.

Serving size13.2 Gram(s) Dosage formPowder Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Betaine Anhydrous

No known
interactions
2500 mg per serving

Betaine anhydrous (also called trimethylglycine) is a compound found in foods like beets, spinach, and whole grains, and is sold as a supplement and a...

Betaine Anhydrous monograph & interactions

L-Carnitine-L-Tartrate

Interacts with
19 drugs
2000 mg per serving

L-carnitine is a compound your body makes naturally and also gets from foods like meat. It helps cells turn fat into energy, and supplements are most...

L-Carnitine-L-Tartrate monograph & interactions

Calcium

Interacts with
168 drugs
220 mg per serving Form: {Alpha}-Hydroxyisocaproate Calcium Salt

Calcium is an essential mineral your body needs for strong bones, nerve signaling, and muscle function, and supplements can help fill gaps when diet f...

Calcium monograph & interactions

Creatine Anhydrous

No known
interactions
3000 mg per serving

Creatine is one of the most studied sports supplements, with solid evidence that it can boost strength and performance during short, high-intensity ac...

Creatine Anhydrous monograph & interactions

TruGlutamine Blend

2500 mg per serving

Hydroxy-Isocaproic Acid

1500 mg per serving Form: {Alpha}-Hydroxyisocaproate Calcium Salt

PerfomaLean Blend

1100 mg per serving

Other (inactive) ingredients: Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.

Interaction report

Ergonine Flavorless by PEScience Drug Interactions

Want to check YOUR meds against Ergonine Flavorless?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
455Drugs
7 Major 430 Moderate 18 Minor

Ingredients driving the most interactions

Calcium 168
L-Carnitine-L-Tartrate 19

Individual Drug Interactions

The ingredients in Ergonine Flavorless interact with 455 drugs. Click any drug to see the details.

2 of the 7 ingredients in Ergonine Flavorless interact with drugs. Each result below shows which ingredient is responsible. Calcium L-Carnitine-L-Tartrate

Each ingredient & the kinds of drugs it affects

For each ingredient in Ergonine Flavorless with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Calcium18 drug types · 168 drugs

Ceftriaxone (Rocephin)

Co-administration of intravenous calcium and ceftriaxone can result in precipitation of a ceftriaxone-calcium salt in the lungs and kidneys.
Avoid administering intravenous calcium in any form, such as parenteral nutrition or Lactated Ringers, within 48 hours of intravenous ceftriaxone. Case reports in neonates show that administering intravenous ceftriaxone and calcium can result in precipitation of a ceftriaxone-calcium salt in the lungs and kidneys. In several cases, neonates have died as a result of this interaction. So far there are no reports in adults; however, there is still concern that this interaction might occur in adults.

Likelihood Probable Evidence D
Dolutegravir (Tivicay)

Calcium seems to reduce levels of dolutegravir.
Advise patients to take dolutegravir either 2 hours before or 6 hours after taking calcium supplements. Pharmacokinetic research suggests that taking calcium carbonate 1200 mg concomitantly with dolutegravir 50 mg reduces plasma levels of dolutegravir by almost 40%. Calcium appears to decrease levels of dolutegravir through chelation.

Likelihood Probable Evidence B
Elvitegravir (Vitekta)

Calcium seems to reduce levels of elvitegravir.
Advise patients to take elvitegravir either 2 hours before or 2 hours after taking calcium supplements. Pharmacokinetic research suggests that taking calcium along with elvitegravir can reduce blood levels of elvitegravir through chelation.

Likelihood Probable Evidence B
Aluminum

Calcium citrate might increase aluminum absorption and toxicity. Other types of calcium do not increase aluminum absorption.
Calcium citrate can increase the absorption of aluminum when taken with aluminum hydroxide. The increase in aluminum levels may become toxic, particularly in individuals with kidney disease. However, the effect of calcium citrate on aluminum absorption is due to the citrate anion rather than calcium cation. Calcium acetate does not appear to increase aluminum absorption.

Likelihood Possible Evidence B
Bictegravir/Emtricitabine/Tenofovir Alafenamide (Biktarvy)

Calcium might decrease levels of bictegravir/emtricitabine/tenofovir alafenamide by reducing its absorption when taken in a fasting state.
Advise patients that bictegravir/emtricitabine/tenofovir alafenamide and calcium can be taken together if taken with food. However, if taken on an empty stomach, bictegravir/emtricitabine/tenofovir alafenamide should not be taken with, or 2 hours after, calcium containing products.

Likelihood Probable Evidence D
Bisphosphonates

Calcium reduces the absorption of bisphosphonates.
Advise patients to take bisphosphonates at least 30 minutes before calcium, but preferably at a different time of day. Calcium supplements decrease absorption of bisphosphonates.

Likelihood Probable Evidence C
Calcipotriene (Dovonex)

Taking calcipotriene with calcium might increase the risk for hypercalcemia.
Calcipotriene is a vitamin D analog used topically for psoriasis. It can be absorbed in sufficient amounts to cause systemic effects, including hypercalcemia. Theoretically, combining calcipotriene with calcium supplements might increase the risk of hypercalcemia.

Likelihood Possible Evidence B
Digoxin (Lanoxin)

Using intravenous calcium with digoxin might increase the risk of fatal cardiac arrhythmias.
Hypercalcemia increases the risk of fatal cardiac arrhythmias with digoxin. However, one retrospective analysis of clinical data suggests that intravenous calcium does not increase the risk of dysrhythmias or mortality in patients receiving digoxin.

Likelihood Possible Evidence B
Diltiazem (Cardizem, Others)

Theoretically, calcium may reduce the therapeutic effects of diltiazem.
Hypercalcemia can reduce the effectiveness of verapamil in atrial fibrillation. Theoretically, calcium might increase this risk of hypercalcemia and reduce the effectiveness of diltiazem.

Likelihood Probable Evidence D
Levothyroxine (Synthroid, Others)

Calcium seems to reduce the absorption and effectiveness of levothyroxine.
Advise patients to take levothyroxine and calcium supplements at least 4 hours apart. Calcium reduces levothyroxine absorption, probably by forming insoluble complexes. Calcium carbonate supplements reduce effectiveness of levothyroxine in patients with hypothyroidism.

Likelihood Probable Evidence B
Lithium

Theoretically, concomitant use of calcium and lithium may increase this risk of hypercalcemia.
Clinical research suggests that long-term use of lithium may cause hypercalcemia in 10% to 60% of patients. Theoretically, concomitant use of lithium and calcium supplements may further increase this risk.

Likelihood Possible Evidence B
Quinolone Antibiotics

Calcium seems to reduce the absorption of quinolone antibiotics.
Advise patients to take oral quinolones at least 2 hours before or 4-6 hours after calcium supplements or calcium-fortified foods. Taking calcium at the same time as oral quinolones can reduce quinolone absorption. Calcium binds to quinolones in the gut.

Likelihood Probable Evidence B
Raltegravir (Isentress)

Calcium may reduce levels of raltegravir.
Pharmacokinetic research shows that taking a single dose of calcium carbonate 3000 mg along with raltegravir 400 mg twice daily modestly decreases the mean area under the curve of raltegravir, but the decrease does not necessitate a dose adjustment of raltegravir. However, a case of elevated HIV-1 RNA levels and documented resistance to raltegravir has been reported for a patient taking calcium carbonate 1 gram three times daily plus vitamin D3 (cholecalciferol) 400 IU three times daily in combination with raltegravir 400 mg twice daily for 11 months. It is thought that calcium reduced raltegravir levels by chelation, leading to treatment failure.

Likelihood Possible Evidence B
Sotalol (Betapace)

Calcium seems to reduce the absorption of sotalol.
Advise patients to separate doses by at least 2 hours before or 4-6 hours after calcium. Calcium appears to reduce the absorption of sotalol, probably by forming insoluble complexes.

Likelihood Possible Evidence B
Tetracycline Antibiotics

Calcium seems to reduce the absorption of tetracycline antibiotics.
Advise patients to take oral tetracyclines at least 2 hours before, or 4-6 hours after calcium supplements. Taking calcium at the same time as oral tetracyclines can reduce tetracycline absorption. Calcium binds to tetracyclines in the gut.

Likelihood Probable Evidence C
Thiazide Diuretics

Taking calcium along with thiazides might increase the risk of hypercalcemia and renal failure.
Thiazides reduce calcium excretion by the kidneys. Using thiazides along with moderately large amounts of calcium carbonate increases the risk of milk-alkali syndrome (hypercalcemia, metabolic alkalosis, renal failure). Patients may need to have their serum calcium levels and/or parathyroid function monitored regularly.

Likelihood Probable Evidence C
Verapamil (Calan, Others)

Theoretically, calcium may reduce the therapeutic effects of verapamil.
Hypercalcemia can reduce the effectiveness of verapamil in atrial fibrillation. Theoretically, use of calcium supplements may increase this risk of hypercalcemia and reduce the effectiveness of verapamil.

Likelihood Probable Evidence D
Calcium Channel Blockers

Intravenous calcium may decrease the effects of calcium channel blockers; oral calcium is unlikely to have this effect.
Intravenous calcium is used to decrease the effects of calcium channel blockers in the management of overdose. Intravenous calcium gluconate has been used before intravenous verapamil (Isoptin) to prevent or reduce the hypotensive effects without affecting the antiarrhythmic effects. But there is no evidence that dietary or supplemental calcium when taken orally interacts with calcium channel blockers.

Likelihood Unlikely Evidence D
Calcium full monograph & interactions

L-Carnitine-L-Tartrate3 drug types · 19 drugs

Acenocoumarol (Sintrom)

Theoretically, L-carnitine might increase the anticoagulant effects of acenocoumarol.
L-carnitine might enhance the anticoagulant effects of acenocoumarol, an oral anticoagulant similar to warfarin, but shorter-acting. There are at least two case reports of INR elevation with concomitant use. In one case, a 33-year-old male with a previously stable INR had an elevated INR of 4.65 after L-carnitine was started and continued for 10 weeks. INR normalized after discontinuation of the L-carnitine-containing product.

Likelihood Possible Evidence D
Thyroid Hormone

Theoretically, L-carnitine might decrease the effectiveness of thyroid hormone replacement.
L-carnitine appears to act as a peripheral thyroid hormone antagonist by inhibiting entry of thyroid hormone into the nucleus of cells. Taking L-carnitine also seems to diminish some of the symptoms of hyperthyroidism.

Likelihood Probable Evidence B
Warfarin (Coumadin)

Theoretically, L-carnitine might increase the anticoagulant effects of warfarin.
L-carnitine might increase the anticoagulant effects of acenocoumarol, a shorter-acting oral anticoagulant similar to warfarin. There is not enough information to know whether this interaction occurs with L-carnitine and warfarin.

Likelihood Possible Evidence D
L-Carnitine-L-Tartrate full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Ergonine Flavorless, from the product label.

PEScience

See all PEScience products
Name
Physique Enhancing Science
Street Address
3665 East Bay Dr #204-155
City
Largo
State
FL
ZipCode
33771
Phone Number
888-885-0195
Web Address
PESCIENCE.COM
Pharmacist Counseling Corner

Ergonine Flavorless by PEScience: Common Questions

Does Ergonine Flavorless by PEScience interact with any medications?
Yes. Based on its ingredients, Ergonine Flavorless has a known interaction with 455 medications, including 7 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Ergonine Flavorless contains 7 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm on levothyroxine for my thyroid?
Not without checking first. Both calcium and L-carnitine in this product can reduce how well your thyroid medication works. Talk to your doctor or pharmacist—you may need to space out when you take them or adjust your dose.
Is this safe during pregnancy?
That depends on the ingredient. L-glutamine, L-alanine, choline, and calcium are likely safe in normal amounts. However, creatine should be avoided, asafoetida is likely unsafe, and we don't have pregnancy safety data for several of the blends. Discuss with your obstetrician or midwife before taking it.
What does L-glutamine do in this product?
L-glutamine is an amino acid your body uses for muscle repair and gut health. It's effective for sickle cell disease and possibly helpful for recovery after surgery or trauma and for muscle wasting in HIV/AIDS.
Will this help my athletic performance?
Creatine in this product is possibly effective for muscle strength and athletic performance. L-carnitine is possibly effective for endurance and reducing fatigue, though evidence is mixed. Results vary by person and depend on your training and diet too.
What side effects should I expect?
Common mild side effects include bloating, gas, diarrhea, and nausea, especially at higher doses. Some people notice a fishy body odor from choline or carnitine. Rare serious effects (like kidney problems from creatine) are very uncommon in healthy people, but those with kidney disease should be cautious.
Can I take this if I'm on a blood thinner like warfarin?
Not without checking with your doctor first. L-carnitine in this product may increase warfarin's blood-thinning effect, and asafoetida may raise bleeding risk. Your doctor can advise whether it's safe for you and whether you need monitoring.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Ergonine Flavorless label
Go deeper

The Full Monographs Behind Ergonine Flavorless’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Betaine Anhydrous

Betaine anhydrous (also called trimethylglycine) is a compound found in foods like beets, spinach, and whole grains, and is sold as a supplement and as a prescription medicine for a rare gen...

Read the full Betaine Anhydrous monograph → Herb & supplement monograph

Glutamine

Interacts with 50 drugs

Glutamine is the most abundant amino acid in the body and is usually made in your muscles. A prescription form is FDA-approved to help reduce sickle cell disease complications, but for most...

Read the full Glutamine monograph → Herb & supplement monograph

Alpha-alanine

Alpha-alanine (usually called alanine) is a non-essential amino acid your body can make on its own and that you also get from protein foods. Most people do not need a supplement, and strong...

Read the full Alpha-alanine monograph → Herb & supplement monograph

Choline

Interacts with 16 drugs

Choline is an essential nutrient your body needs for liver function, brain health, and nerve signaling, and many people get enough from foods like eggs, meat, and fish. Supplements may help...

Read the full Choline monograph → Herb & supplement monograph

Glycerol

Glycerol (glycerin) is a sweet, syrupy compound made naturally in the body and widely used in foods, skin products, and medicines. It is well established as a laxative and a skin and eye moi...

Read the full Glycerol monograph → Herb & supplement monograph

Asafoetida

Interacts with 289 drugs

Asafoetida is a strong-smelling plant resin used widely as a spice and in traditional medicine, mainly for digestive complaints. Solid human evidence for its medicinal benefits is limited, t...

Read the full Asafoetida monograph → Herb & supplement monograph

L-carnitine

Interacts with 19 drugs

L-carnitine is a compound your body makes naturally and also gets from foods like meat. It helps cells turn fat into energy, and supplements are most clearly useful for people with a true ca...

Read the full L-carnitine monograph → Herb & supplement monograph

Calcium

Interacts with 168 drugs

Calcium is an essential mineral your body needs for strong bones, nerve signaling, and muscle function, and supplements can help fill gaps when diet falls short. Most people do best getting...

Read the full Calcium monograph → Herb & supplement monograph

Creatine

Creatine is one of the most studied sports supplements, with solid evidence that it can boost strength and performance during short, high-intensity activities like weightlifting and sprintin...

Read the full Creatine monograph →
Sources

Sources & How We Checked

Ergonine Flavorless's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 239 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Glutamine 11 references
  1. Miller AL. Therapeutic considerations of L-glutamine: a review of the literature. Altern Med Rev 1999;4:239-48..
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Alpha-alanine 2 references
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Choline 14 references
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Betaine Anhydrous 11 references
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See these in context on the Calcium monograph →

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Glycerol 8 references
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See these in context on the Glycerol monograph →

Asafoetida 4 references
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