Essential Female Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Essential Female against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Essential Female is a dietary supplement by Organic India with 4 active ingredients. Its ingredients are commonly taken for women's reproductive health, promoting breast milk supply, digestive complaints.Based on those ingredients, 674 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are organic Guduchi, Shatavari. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Essential Female by Organic India
Ask about any prescription or over-the-counter medication and we check it for interactions with Essential Female by Organic India — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Essential Female by Organic India
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
Essential Female contains 4 active ingredients: Shatavari (Asparagus racemosus), organic Guduchi (Tinospora cordifolia), organic Vana Tulsi, and Lodhra. These are traditional Ayurvedic plants used to support female reproductive and hormonal health.
The capsules themselves are made from organic vegetable pullulan, an inactive ingredient that serves as the capsule shell.
Does it work?
Not established
Evidence for these ingredients is limited. Guduchi is possibly effective for type 2 diabetes, based on clinical research showing it can lower fasting blood sugar.
For Shatavari, the data we hold shows insufficient evidence to rate its effects on lactation, muscle strength, sexual desire, tuberculosis, and bronchitis — meaning we don't yet have reliable research backing its traditional uses. No effectiveness rating is established in our data for Vana Tulsi or Lodhra.
How safe is it?
Well-documented data
Shatavari is generally well tolerated in traditional use, but high-quality safety data are limited. Safety during pregnancy is not well established, so it's best avoided unless your doctor advises otherwise.
It's traditionally used to support milk supply, but reliable safety data are lacking — use it while breastfeeding only under professional guidance. Guduchi is also generally well tolerated by mouth, with the most common side effects being headache and nasal pain.
However, liver injury has been reported — in one series of cases, 49 patients developed autoimmune hepatitis, acute hepatitis, or acute liver failure after taking Guduchi alone or in combination products over 42–90 days; 2 required transplants and 4 died. Safety during pregnancy is not well established, so it's best avoided.
It should not be used while breastfeeding due to insufficient safety information. No safety data is on file for Vana Tulsi or Lodhra.
Meds to double-check
Moderate interaction found
Check with your doctor or pharmacist before taking this product if you use immunosuppressants, antidiabetes drugs, diuretics, or lithium (all Moderate interactions). Additionally, confirm any medications your liver breaks down — including certain antidepressants, blood thinners, and heart drugs — since Guduchi may raise their levels.
No interactions are documented for Vana Tulsi and Lodhra, as we hold no data for them.
The bottom line
Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.
Essential Female is designed for female hormonal and reproductive support using traditional Ayurvedic ingredients, though evidence is limited for most of them. If you take any medications — especially immunosuppressants, diabetes drugs, diuretics, lithium, or drugs your liver breaks down — you need to check them against this product before starting.
Talk with your doctor or pharmacist about whether it's right for you, particularly if you're pregnant, breastfeeding, or have liver concerns.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 2 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jul 21, 2022.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Essential Female, straight from the product label.
| Brand | Organic India |
|---|---|
| Barcode (UPC) | 801541519323 |
| Net contents | 90 Veg Cap(s) |
| Market status | On market |
| Date entered into DSLD | Jul 21, 2022 |
| DSLD ID | 268093 |
| Product type | Botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Vegan, Vegetarian, Kosher, Organic, Adult Female (18 - 50 Years), Halal |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Essential Female by Organic India, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Shatavari | 530 mg | -- |
| organic Guduchi | 90 mg | -- |
| organic Vana Tulsi | 50 mg | -- |
| Lodhra | 30 mg | -- |
Other ingredients: organic Vegetable Pullulan Capsules
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements
At the heart of organic India is our commitment to be a living embodiment of love and consciousness in action. Whole herb solutions grown sustainably by small family farmers using regenerative organic agriculture. Healthy conscious living
Mfg. Lic. No. A-2755
For export to USA only
Formulation
Essential Female is a nourishing tonic for maintaining a healthy reproductive system. Promoting hormonal balance and vitality, this unique formula contains ancient Ayurvedic herbs to support women through all stages of life.
Vegan - Vegetarian
Gluten free
Hormonal balance
USDA Organic Product produced and processed according to NPOP standard of India & USDA-NOP www.controlunion.com
Product of India
Formula
Promoting hormonal balance and vitality, this unique formula contains ancient Ayurvedic herbs to support women through all stages of life.
OU Kosher
Halal Mumbai India Halal Committee Registration No. 0854
Suggested/Recommended/Usage/Directions
Suggested Use: 2 capsules with food and water twice daily, not to exceed 6 capsules per day.
Precautions
Do not use if pregnant or nursing without consulting a physician.
Warning: Reproductive Harm - www.P65Warnings.ca.gov
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
FDA Statement of Identity
Herbal Supplement
Seals/Symbols
USDA Organic Non GMO Project Verified nongmoproject.org Certified B Corporation Control Union Certified NPOP/NAB/0010 Certified Organic by Control Union-CU801983
Halal Mumbai India Halal Committee Registration No. 0854 OU Kosher
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Essential Female by Organic India label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Essential Female by Organic India
These are the 4 active ingredients this product is made of. Select any to open its full monograph.
Serving size2 Capsule(s) Dosage formCapsule Servings per container45 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Shatavari
Interacts with76 drugs
Asparagus racemosus, often called shatavari, is an Ayurvedic herb traditionally used to support women's health, digestion, and overall vitality. Human...
Shatavari monograph & interactionsOrganic Guduchi
Interacts with612 drugs
Tinospora cordifolia, known as Guduchi or Giloy in Ayurvedic medicine, is a climbing plant traditionally used to support immunity and treat fevers. Ea...
Organic Guduchi monograph & interactionsOrganic Vana Tulsi
Lodhra
Other (inactive) ingredients: Organic Vegetable Pullulan Capsules. These complete the product’s ingredient list but are not active constituents.
Essential Female by Organic India Drug Interactions
HelloPharmacist Interaction Report
Essential Female by Organic India contains Shatavari and Guduchi, both of which interact with medications.
The most serious concern is Guduchi's interaction with immunosuppressants (Moderate severity) — this ingredient may reduce how well these drugs work to prevent your body from rejecting a transplant or attacking itself. Guduchi also affects several groups of drugs your liver breaks down: CYP2D6 substrates, CYP2C19 substrates, CYP1A2 substrates, and CYP2C9 substrates (all Moderate severity).
In theory, it could raise levels of these medications, though this hasn't been observed in humans yet. Additionally, Guduchi may increase low blood sugar (hypoglycemia) risk if you take diabetes medications, and it could boost diuresis (fluid loss) and electrolyte imbalance with diuretic drugs.
Read the full breakdown — every affected drug type, severity by severity
Shatavari adds two more concerns: it may worsen electrolyte loss when combined with diuretics (Moderate), and it could increase lithium levels, potentially requiring a dose adjustment (Moderate). Altogether, these interactions span 674 individual medications.
We couldn't check Vana Tulsi or Lodhra — no monograph data is on file for them. Use the search tool below to look up your exact medications before starting this product.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Essential Female?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Essential Female interact with 674 drugs. Click any drug to see the details.
2 of the 4 ingredients in Essential Female interact with drugs. Each result below shows which ingredient is responsible. organic Guduchi Shatavari
6-mercaptopurinePurinethol
How 6-mercaptopurine interacts with Essential Female — through 1 ingredient. Tap an ingredient for the detail:
Organic GuduchiImmunosuppressants Moderate
Interaction Summary
Theoretically, Tinospora cordifolia might reduce the effectiveness of immunosuppressants.
Read the full Organic Guduchi + 6-mercaptopurine interactionAbrocitinibCibinqo
How Abrocitinib interacts with Essential Female — through 1 ingredient. Tap an ingredient for the detail:
Organic GuduchiCytochrome P450 2c9 (cyp2c9) Substrates, Immunosuppressants +1 Moderate
Interaction Summary
Theoretically, Tinospora cordifolia might increase levels of drugs metabolized by CYP2C9.
Read the full Organic Guduchi + Abrocitinib interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Essential Female — through 1 ingredient. Tap an ingredient for the detail:
Organic GuduchiAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, Tinospora cordifolia might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Organic Guduchi + Acarbose interactionAcetaminophenChildren's Tylenol, Children's Tylenol Meltaways, Tylenol, Tylenol Ex Strength
How Acetaminophen interacts with Essential Female — through 1 ingredient. Tap an ingredient for the detail:
Organic GuduchiCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, Tinospora cordifolia might increase levels of drugs metabolized by CYP1A2.
Read the full Organic Guduchi + Acetaminophen interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Essential Female — through 1 ingredient. Tap an ingredient for the detail:
Organic GuduchiCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, Tinospora cordifolia might increase levels of drugs metabolized by CYP1A2.
Read the full Organic Guduchi + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Essential Female — through 1 ingredient. Tap an ingredient for the detail:
Organic GuduchiCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, Tinospora cordifolia might increase levels of drugs metabolized by CYP1A2.
Read the full Organic Guduchi + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Brompheniramine, PhenylpropanolamineDimetapp Cold and Flu
How Acetaminophen, Brompheniramine, Phenylpropanolamine interacts with Essential Female — through 1 ingredient. Tap an ingredient for the detail:
Organic GuduchiCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, Tinospora cordifolia might increase levels of drugs metabolized by CYP1A2.
Read the full Organic Guduchi + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionAcetaminophen, ButalbitalAxocet, Bancap, Bucet, Butex Forte, Esgic CF, Orbivan CF +5 more
How Acetaminophen, Butalbital interacts with Essential Female — through 1 ingredient. Tap an ingredient for the detail:
Organic GuduchiCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, Tinospora cordifolia might increase levels of drugs metabolized by CYP1A2.
Read the full Organic Guduchi + Acetaminophen, Butalbital interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with Essential Female — through 1 ingredient. Tap an ingredient for the detail:
Organic GuduchiCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, Tinospora cordifolia might increase levels of drugs metabolized by CYP1A2.
Read the full Organic Guduchi + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with Essential Female — through 1 ingredient. Tap an ingredient for the detail:
Organic GuduchiCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, Tinospora cordifolia might increase levels of drugs metabolized by CYP1A2.
Read the full Organic Guduchi + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Butalbital, CodeineBancap w/ Codeine
How Acetaminophen, Butalbital, Codeine interacts with Essential Female — through 1 ingredient. Tap an ingredient for the detail:
Organic GuduchiCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, Tinospora cordifolia might increase levels of drugs metabolized by CYP2D6.
Read the full Organic Guduchi + Acetaminophen, Butalbital, Codeine interactionAcetaminophen, Butalbital, Codeine PhosphatePhrenilin #3
How Acetaminophen, Butalbital, Codeine Phosphate interacts with Essential Female — through 1 ingredient. Tap an ingredient for the detail:
Organic GuduchiCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, Tinospora cordifolia might increase levels of drugs metabolized by CYP1A2.
Read the full Organic Guduchi + Acetaminophen, Butalbital, Codeine Phosphate interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with Essential Female — through 1 ingredient. Tap an ingredient for the detail:
Organic GuduchiCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, Tinospora cordifolia might increase levels of drugs metabolized by CYP2D6.
Read the full Organic Guduchi + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with Essential Female — through 1 ingredient. Tap an ingredient for the detail:
Organic GuduchiCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, Tinospora cordifolia might increase levels of drugs metabolized by CYP1A2.
Read the full Organic Guduchi + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with Essential Female — through 1 ingredient. Tap an ingredient for the detail:
Organic GuduchiCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, Tinospora cordifolia might increase levels of drugs metabolized by CYP2D6.
Read the full Organic Guduchi + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with Essential Female — through 1 ingredient. Tap an ingredient for the detail:
Organic GuduchiCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, Tinospora cordifolia might increase levels of drugs metabolized by CYP1A2.
Read the full Organic Guduchi + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Caffeine, IsomethepteneMigralam
How Acetaminophen, Caffeine, Isometheptene interacts with Essential Female — through 1 ingredient. Tap an ingredient for the detail:
Organic GuduchiCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, Tinospora cordifolia might increase levels of drugs metabolized by CYP1A2.
Read the full Organic Guduchi + Acetaminophen, Caffeine, Isometheptene interactionAcetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with Essential Female — through 2 ingredients. Tap an ingredient for the detail:
Organic GuduchiCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, Tinospora cordifolia might increase levels of drugs metabolized by CYP1A2.
Read the full Organic Guduchi + Acetaminophen, Caffeine, Pyrilamine interactionShatavariDiuretic Drugs Moderate
Interaction Summary
Theoretically, asparagus racemosus root might increase diuresis and electrolyte loss when used with diuretic drugs.
Read the full Shatavari + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, Chlorpheniramine Maleate, Dextromethorphan HbrVicks Formula 44M Cough, Cold & Flu Relief
How Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interacts with Essential Female — through 1 ingredient. Tap an ingredient for the detail:
Organic GuduchiCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, Tinospora cordifolia might increase levels of drugs metabolized by CYP2D6.
Read the full Organic Guduchi + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionAcetaminophen, Chlorpheniramine, Codeine, PhenylephrineColrex
How Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interacts with Essential Female — through 1 ingredient. Tap an ingredient for the detail:
Organic GuduchiCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, Tinospora cordifolia might increase levels of drugs metabolized by CYP1A2.
Read the full Organic Guduchi + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, DextromethorphanCoricidin II Extra Strength Cold and Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan interacts with Essential Female — through 1 ingredient. Tap an ingredient for the detail:
Organic GuduchiCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, Tinospora cordifolia might increase levels of drugs metabolized by CYP2D6.
Read the full Organic Guduchi + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionAcetaminophen, Chlorpheniramine, Dextromethorphan HydrobromideCoricidin HBP Maximum Strength Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interacts with Essential Female — through 1 ingredient. Tap an ingredient for the detail:
Organic GuduchiCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, Tinospora cordifolia might increase levels of drugs metabolized by CYP1A2.
Read the full Organic Guduchi + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PhenylpropanolamineMulti Symptom Cold Relief
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interacts with Essential Female — through 1 ingredient. Tap an ingredient for the detail:
Organic GuduchiCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, Tinospora cordifolia might increase levels of drugs metabolized by CYP2D6.
Read the full Organic Guduchi + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PseudoephedrineChildren's Tylenol Cold Plus Cough, Tylenol Cold Ex Strength
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interacts with Essential Female — through 1 ingredient. Tap an ingredient for the detail:
Organic GuduchiCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, Tinospora cordifolia might increase levels of drugs metabolized by CYP1A2.
Read the full Organic Guduchi + Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interactionAcetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, SalicylamideRhinogesic GG
How Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interacts with Essential Female — through 1 ingredient. Tap an ingredient for the detail:
Organic GuduchiCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, Tinospora cordifolia might increase levels of drugs metabolized by CYP1A2.
Read the full Organic Guduchi + Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interactionAcetaminophen, Chlorpheniramine, PhenylephrineAlka-Seltzer PLUS, Histex SR, Protid
How Acetaminophen, Chlorpheniramine, Phenylephrine interacts with Essential Female — through 1 ingredient. Tap an ingredient for the detail:
Organic GuduchiCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, Tinospora cordifolia might increase levels of drugs metabolized by CYP1A2.
Read the full Organic Guduchi + Acetaminophen, Chlorpheniramine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, Phenylephrine, SalicylamideRhinogesic, Rhinogesic JR
How Acetaminophen, Chlorpheniramine, Phenylephrine, Salicylamide interacts with Essential Female — through 1 ingredient. Tap an ingredient for the detail:
Organic GuduchiCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, Tinospora cordifolia might increase levels of drugs metabolized by CYP1A2.
Read the full Organic Guduchi + Acetaminophen, Chlorpheniramine, Phenylephrine, Salicylamide interactionAcetaminophen, Chlorpheniramine, PhenylpropanolamineAlumadrine, Conex, Sinadrin Max Strength, Sinulin
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine interacts with Essential Female — through 1 ingredient. Tap an ingredient for the detail:
Organic GuduchiCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, Tinospora cordifolia might increase levels of drugs metabolized by CYP1A2.
Read the full Organic Guduchi + Acetaminophen, Chlorpheniramine, Phenylpropanolamine interactionAcetaminophen, Chlorpheniramine, Phenylpropanolamine, OpiumHista-Derfule
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Opium interacts with Essential Female — through 1 ingredient. Tap an ingredient for the detail:
Organic GuduchiCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, Tinospora cordifolia might increase levels of drugs metabolized by CYP1A2.
Read the full Organic Guduchi + Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Opium interactionAcetaminophen, Chlorpheniramine, Phenylpropanolamine, PhenyltoloxamineNorel Plus
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Phenyltoloxamine interacts with Essential Female — through 1 ingredient. Tap an ingredient for the detail:
Organic GuduchiCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, Tinospora cordifolia might increase levels of drugs metabolized by CYP1A2.
Read the full Organic Guduchi + Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Phenyltoloxamine interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Essential Female with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
organic Guduchi
Antidiabetes Drugs
Theoretically, Tinospora cordifolia might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Clinical research in adults with type 2 diabetes shows that Tinospora cordifolia can reduce fasting blood glucose and glycated hemoglobin. Additionally, animal research shows that Tinospora cordifolia has hypoglycemic effects.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, Tinospora cordifolia might increase levels of drugs metabolized by CYP1A2.
In vitro research shows that Tinospora cordifolia extract inhibits CYP1A2 at high concentrations. However, this interaction has not been reported in humans.
Cytochrome P450 2C19 (Cyp2C19) Substrates
Theoretically, Tinospora cordifolia might increase levels of drugs metabolized by CYP2C19.
In vitro research shows that Tinospora cordifolia extract inhibits CYP2C19 at high concentrations. However, this interaction has not been reported in humans.
Cytochrome P450 2C9 (Cyp2C9) Substrates
Theoretically, Tinospora cordifolia might increase levels of drugs metabolized by CYP2C9.
In vitro research shows that Tinospora cordifolia extract inhibits CYP2C9. Animal research shows that Tinospora cordifolia extract 400 mg/kg twice daily for 14 days reduces the clearance and increases plasma levels of glyburide, a CYP2C9 substrate. However, this interaction has not been reported in humans.
Cytochrome P450 2D6 (Cyp2D6) Substrates
Theoretically, Tinospora cordifolia might increase levels of drugs metabolized by CYP2D6.
In vitro research shows that Tinospora cordifolia extract inhibits CYP2D6 at high concentrations. However, this interaction has not been reported in humans.
Immunosuppressants
Theoretically, Tinospora cordifolia might reduce the effectiveness of immunosuppressants.
In vitro and animal research shows that Tinospora cordifolia has immunostimulant effects.
Shatavari
Diuretic Drugs
Theoretically, asparagus racemosus root might increase diuresis and electrolyte loss when used with diuretic drugs.
Animal studies show that asparagus racemosus root has diuretic effects when used in high doses. This effect has not been reported in humans.
Lithium
Theoretically, Asparagus racemosus root could reduce excretion and increase levels of lithium.
Animal research suggests that Asparagus racemosus root has diuretic properties when used in high doses. Therefore, it might reduce excretion and increase levels of lithium. The dose of lithium might need to be decreased.
Brand information
Manufacturer and brand details for Essential Female, from the product label.
Organic India
See all Organic India products- Name
- Organic India Pvt. Ltd.
- Street Address
- Factory: C-5/10, Agro Park Phase -II UPSIDC Industrial Area, Kursi Road
- City
- Barabanki
- State
- U.P.
- ZipCode
- 225302
Essential Female by Organic India: Common Questions
Does Essential Female by Organic India interact with any medications?
How can one product interact with so many drugs?
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Is this safe in pregnancy?
Can Guduchi help with diabetes?
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Does this contain any fillers?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Essential Female’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Asparagus Racemosus
Interacts with 76 drugsAsparagus racemosus, often called shatavari, is an Ayurvedic herb traditionally used to support women's health, digestion, and overall vitality. Human evidence for most of these uses is limi...
Read the full Asparagus Racemosus monograph → Herb & supplement monographTinospora Cordifolia
Interacts with 612 drugsTinospora cordifolia, known as Guduchi or Giloy in Ayurvedic medicine, is a climbing plant traditionally used to support immunity and treat fevers. Early laboratory and small human studies s...
Read the full Tinospora Cordifolia monograph →Sources & How We Checked
Essential Female's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 17 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Asparagus Racemosus 1 reference
- Satish Kumar MC, Udupa AL, Sammodavardhana K, Rathnakar UP, Shvetha U, Kodancha GP. Acute toxicity and diuretic studies of the roots of Asparagus racemosus Willd in rats. West Indian Med J. 2010;59(1):3-6.
Tinospora Cordifolia 16 references
- Stanely Mainzen Prince P, Menon VP. Hypoglycaemic and hypolipidaemic action of alcohol extract of Tinospora cordifolia roots in chemical induced diabetes in rats. Phytother Res 2003;17:410-3.
- Grover JK, Vats V, Rathi SS. Anti-hyperglycemic effect of Eugenia jambolana and Tinospora cordifolia in experimental diabetes and their effects on key metabolic enzymes involved in carbohydrate metabolism. J Ethnopharmacol 2000;73:461-70. PubMed
- Manjrekar PN, Jolly CI, Narayanan S. Comparative studies of the immunomodulatory activity of Tinospora cordifolia and Tinospora sinensis. Fitoterapia 2000;71:254-7. PubMed
- Prince PS, Menon VP. Antioxidant activity of Tinospora cordifolia roots in experimental diabetes. J Ethnopharmacol 1999;65:277-81. PubMed
- Stanely Mainzen Prince P, Menon VP, Gunasekaran G. Hypolipidaemic action of Tinospora cordifolia roots in alloxan diabetic rats. J Ethnopharmacol 1999;64:53-7. PubMed
- Badar VA, Thawani VR, Wakode PT, et al. Efficacy of Tinospora cordifolia in allergic rhinitis. J Ethnopharmacol 2005;96:445-9. PubMed
- Kapil A, Sharma S. Immunopotentiating compounds from Tinospora cordifolia. J Ethnopharmacol 1997;58:89-95. PubMed
- Nair PK, Rodriguez S, Ramachandran R, et al. Immune stimulating properties of a novel polysaccharide from the medicinal plant Tinospora cordifolia. Int Immunopharmacol 2004;4:1645-59. PubMed
- Castillo AL, Osi MO, Ramos JD, De Francia JL, Dujunco MU, Quilala PF. Efficacy and safety of Tinospora cordifolia lotion in Sarcoptes scabiei var hominis-infected pediatric patients: A single blind, randomized controlled trial. J Pharmacol Pharmacother. 2 PubMed
- Sahu R, Ahmed T, Sangana R, Punde R, Subudhi BB. Effect of Tinospora cordifolia aqua-alcoholic extract on pharmacokinetic of glibenclamide in rat: an herb-drug interaction study. J Pharm Biomed Anal. 2018;151:310-6. doi: 10.1016/j.jpba.2018.01.010. PubMed
- Patial V, Katoch S, Chhimwal J, Singh PP, Suresh PS, Padwad Y. Tinospora cordifolia activates PPAR? pathway and mitigates glomerular and tubular cell injury in diabetic kidney disease. Phytomedicine 2021;91:153663. PubMed
- Kulkarni AV, Hanchanale P, Prakash V, et al. Tinospora Cordifolia (Giloy)-Induced Liver Injury During the COVID-19 Pandemic-Multicenter Nationwide Study From India. Hepatol Commun 2022;6(6):1289-1300. PubMed
- Nagral A, Adhyaru K, Rudra OS, Gharat A, Bhandare S. Herbal Immune Booster-Induced Liver Injury in the COVID-19 Pandemic - A Case Series. J Clin Exp Hepatol. 2021;11(6):732-738. PubMed
- Chattopadhyay K, Wang H, Kaur J, et al. Effectiveness and Safety of Ayurvedic Medicines in Type 2 Diabetes Mellitus Management: A Systematic Review and Meta-Analysis. Front Pharmacol. 2022;13:821810. Published 2022 Jun 8. PubMed
- Nnamani I, Tolu-Akinnawo O, Dufera RR, Akintunde A, Maliakkal B. Tinospora cordifolia (Guduchi/Giloy)-Induced Liver Injury: A Case Review. Cureus 2023;15(5):e39793. PubMed
- May K, Jeitler M, Murthy V, Stapelfeldt E, Kessler CS. A Case Report of Acute Hepatitis Involving the Medicinal Herb Tinospora cordifolia Along with Other Variables. J Integr Complement Med 2023;29(5):327-333.
See these in context on the Tinospora Cordifolia monograph →
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC