Tulsi Holy Basil Gotu Kola Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Tulsi Holy Basil Gotu Kola against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Tulsi Holy Basil Gotu Kola is a dietary supplement by Organic India with 2 active ingredients. Its ingredients are commonly taken for stress and anxiety, blood sugar support, respiratory complaints.Based on those ingredients, 743 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are organic Gotu Kola, organic Tulsi (Holy Basil) Blend. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Tulsi Holy Basil Gotu Kola by Organic India
Ask about any prescription or over-the-counter medication and we check it for interactions with Tulsi Holy Basil Gotu Kola by Organic India — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Tulsi Holy Basil Gotu Kola by Organic India
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
This blend contains 4 active ingredients: two varieties of tulsi (holy basil)—Rama and Krishna—plus Vana Tulsi and organic gotu kola. Tulsi is traditionally used for stress and wellness, while gotu kola has a long history in Ayurvedic and traditional medicine.
The product comes as a tea blend with no inactive fillers listed.
Does it work?
Not established
The data on what this blend actually does is limited. For tulsi, the evidence doesn't yet support claims about anxiety, asthma, headaches, respiratory infections, dental plaque, or blood sugar control—the studies so far are too small or the quality isn't high enough to be sure.
Gotu kola fares slightly better: it's possibly effective for venous insufficiency (leg circulation issues) and burns, but possibly ineffective for radiation skin damage and cognitive sharpness. For Alzheimer's disease and anxiety, there isn't enough established evidence either way.
How safe is it?
Well-documented data
Both tulsi varieties are generally well tolerated short-term, but long-term safety data are sparse. The most common side effects from tulsi are loose stools and nausea—a small number of trial participants reported these.
Gotu kola is also generally well tolerated, though gastric irritation and nausea can occur when taken by mouth. There's a rare concern about liver toxicity with gotu kola; four case reports exist, but it's unclear whether gotu kola actually caused the problem or whether contaminants were responsible.
One study using 120 mg daily for 6 months saw no liver changes. During pregnancy, the safety data for tulsi advises against it—animal studies raise concerns and human safety hasn't been established.
Gotu kola also lacks enough safety data in pregnancy and is traditionally avoided. Neither ingredient has sufficient breastfeeding data, so both are best avoided while nursing.
Meds to double-check
Moderate interaction found
Check with your pharmacist if you take blood thinners or antiplatelet drugs (like aspirin, clopidogrel, or warfarin), diabetes medications, pentobarbital or other sedatives, other central nervous system depressants, or drugs that can harm the liver. These are the main medication types the ingredients interact with.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.
If you take blood thinners, diabetes drugs, or sedatives, check with your pharmacist before trying this blend—the interactions are real enough to matter. Short-term use appears generally well tolerated, but long-term safety isn't well studied.
Pregnant or breastfeeding? Skip it and talk to your doctor.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 3 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2015.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Tulsi Holy Basil Gotu Kola, straight from the product label.
| Brand | Organic India |
|---|---|
| Barcode (UPC) | 801541500215 |
| Net contents | 1.21 Ounce(s); 34.2 Gram(s); 18 INFUSION BAGS |
| Market status | On market |
| Date entered into DSLD | Sep 25, 2015 |
| DSLD ID | 50159 |
| Product type | Botanical |
| Supplement form | Other (e.g. Tea Bag) |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Kosher, Organic, Halal, Gluten Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Tulsi Holy Basil Gotu Kola by Organic India, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Proprietary Organic Blend | 1.9 Gram(s) | -- |
| organic Tulsi (Holy Basil) Blend | 0 NP | -- |
| Rama Tulsi | 0 NP | -- |
| Krishna Tulsi | 0 NP | -- |
| Vana Tulsi | 0 NP | -- |
| organic Gotu Kola | 0 NP | -- |
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements
Our Organic India family
Stress-Relieving & Purifying*
Tulsi - Holy Basil is an herb with healing properties that relieve stress and protect the immune system.*
When the mind, one pointed and fully focused, knows the supreme silence in the Heart, this is true learning. -Sri Ramana Maharshi-
Organic India is committed to responsible packaging. This carton is made from 100% recycled paperboard, with a minimum of 30% post-consumer content. Our infusion bags are made from unbleached, biodegradable fiber.
Tulsi - A legacy of good health -Reduces stress* -Supports the immune system* -Abundant in antioxidants* -Builds stamina* -Powerful adaptogen* -Anti digestion* -Anti aging* -Balances metabolism* -Balances energy levels* -Uplifts mood*
Tulsi Gotu Kola Two of India's most nourishing herbs, Tulsi & Gotu Kola, lovingly embrace. This healthful and purifying blend balances your nervous system, offers clarify & calm to your mind and enhances your overall physical & emotional well-being.
- Individually wrapped for freshness
The photo on this package is one of our farmers or a family member.
Mfg. Lic. No. A-2755
Product of India
Product produced and processed according to NPOP standard of India & USDA-NOP
Double the strength when serving iced.
Please support our environment by recycling this package.
About Tulsi Throughout India Tulsi is acclaimed as "The Queen of Herbs" and is revered as a sacred plant infused with healing powers. Traditionally grown in an earthen pot in every family home or garden, Tulsi (also known as Holy Basil) makes a delicious and nourishing herbal 'tea' abundant in a vast array of health benefits.* Tulsi's life-enhancing qualities, repeatedly noted in ancient Indian scriptures dating back over 5,000 years, are now here for your to fully enjoy. Blessings and Namaste!
At the heart of Organic India is our commitment to be a living embodiment of love and consciousness in action. We work with thousands of small family farmers in India to cultivate tens of thousands of acres of sustainable, organic farmland. All Organic India products promote health and True Wellness and are made with loving care. The product you hold in your hands is one link in a chain of love, respect and connectedness between Mother Nature, our farmers, our company and you. By choosing Organic India you are actively participating in our mission to create a sustainable global environment, provide training and a life of dignity to our local farmers, and bring health and happiness to you.
Formulation
Caffeine free
Certified organic
Gluten free
Certified Organic by: Control Union CU Cert No. 801983
FDA Disclaimer Statement
*These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.
General
USOI1402A
FDA Statement of Identity
- Herbal supplement
Seals/Symbols
NON GMO Project VERIFIED nongmoproject.org
USDA ORGANIC
India Organic
OU
HALAL MUMBAI INDIA HALAL COMMITTEE JAMIAT ULAMA - E - MAHARASHTRA Registration No.: 0854
Formula
-Kosher
Precautions
To enjoy while pregnant or nursing, consult a physician before use.
Suggested/Recommended/Usage/Directions
Directions: Pour 8 oz of freshly boiled water over infusion bag in a cup. Cover and steep for 5-10 minutes or longer.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Tulsi Holy Basil Gotu Kola by Organic India label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Tulsi Holy Basil Gotu Kola by Organic India
These are the 2 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 infusion bag Dosage formOther (e.g. Tea Bag) Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Proprietary Organic Blend
Tulsi Holy Basil Gotu Kola by Organic India Drug Interactions
HelloPharmacist Interaction Report
Tulsi Holy Basil Gotu Kola by Organic India contains two tulsi varieties and gotu kola, and both have documented interactions with medications.
The most serious concerns involve blood thinners (anticoagulants and antiplatelet drugs). Holy basil seed oil may theoretically increase bleeding risk, though animal data show this potential effect hasn't been confirmed in humans yet.
Read the full breakdown — every affected drug type, severity by severity
Both Rama and Krishna Tulsi also interact with diabetes medications. Holy basil can lower blood sugar, and small studies show it reduces fasting glucose in type 2 diabetes—so combining it with diabetes drugs raises the risk of low blood sugar (hypoglycemia).
Both tulsi varieties may also increase the sedative effect of pentobarbital, a barbiturate sleep aid, though this hasn't been tested in humans.
Gotu kola adds two more interaction categories. It may enhance the drowsiness from CNS depressants (sedatives, sleep aids, anti-anxiety drugs).
It also theoretically could add to the liver damage risk if taken with hepatotoxic drugs—though case reports exist, gotu kola's role as the actual cause remains unclear.
Vana Tulsi couldn't be checked against our data. Altogether, these interactions span 726 individual medications.
Run your exact prescriptions through the checker below before starting.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Tulsi Holy Basil Gotu Kola?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Tulsi Holy Basil Gotu Kola interact with 743 drugs. Click any drug to see the details.
2 of the 2 ingredients in Tulsi Holy Basil Gotu Kola interact with drugs. Each result below shows which ingredient is responsible. organic Gotu Kola organic Tulsi (Holy Basil) Blend
6-mercaptopurinePurinethol
How 6-mercaptopurine interacts with Tulsi Holy Basil Gotu Kola — through 1 ingredient. Tap an ingredient for the detail:
Organic Gotu KolaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking gotu kola with hepatotoxic drugs might have additive adverse effects.
Read the full Organic Gotu Kola + 6-mercaptopurine interactionAbacavir Sulfate, Dolutegravir, LamivudineTriumeq
How Abacavir Sulfate, Dolutegravir, Lamivudine interacts with Tulsi Holy Basil Gotu Kola — through 1 ingredient. Tap an ingredient for the detail:
Organic Gotu KolaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking gotu kola with hepatotoxic drugs might have additive adverse effects.
Read the full Organic Gotu Kola + Abacavir Sulfate, Dolutegravir, Lamivudine interactionAbacavir, LamivudineEpzicom
How Abacavir, Lamivudine interacts with Tulsi Holy Basil Gotu Kola — through 1 ingredient. Tap an ingredient for the detail:
Organic Gotu KolaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking gotu kola with hepatotoxic drugs might have additive adverse effects.
Read the full Organic Gotu Kola + Abacavir, Lamivudine interactionAbciximabReoPro
How Abciximab interacts with Tulsi Holy Basil Gotu Kola — through 1 ingredient. Tap an ingredient for the detail:
Krishna TulsiAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, holy basil seed oil might increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Read the full Krishna Tulsi + Abciximab interactionAbiraterone
How Abiraterone interacts with Tulsi Holy Basil Gotu Kola — through 1 ingredient. Tap an ingredient for the detail:
Organic Gotu KolaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking gotu kola with hepatotoxic drugs might have additive adverse effects.
Read the full Organic Gotu Kola + Abiraterone interactionAbiraterone AcetateYonsa, Zytiga
How Abiraterone Acetate interacts with Tulsi Holy Basil Gotu Kola — through 1 ingredient. Tap an ingredient for the detail:
Organic Gotu KolaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking gotu kola with hepatotoxic drugs might have additive adverse effects.
Read the full Organic Gotu Kola + Abiraterone Acetate interactionAbrocitinibCibinqo
How Abrocitinib interacts with Tulsi Holy Basil Gotu Kola — through 1 ingredient. Tap an ingredient for the detail:
Krishna TulsiAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, holy basil seed oil might increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Read the full Krishna Tulsi + Abrocitinib interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Tulsi Holy Basil Gotu Kola — through 2 ingredients. Tap an ingredient for the detail:
Krishna TulsiAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, holy basil might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Krishna Tulsi + Acarbose interactionOrganic Gotu KolaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking gotu kola with hepatotoxic drugs might have additive adverse effects.
Read the full Organic Gotu Kola + Acarbose interactionAcebutololRhotral, Sectral
How Acebutolol interacts with Tulsi Holy Basil Gotu Kola — through 1 ingredient. Tap an ingredient for the detail:
Organic Gotu KolaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking gotu kola with hepatotoxic drugs might have additive adverse effects.
Read the full Organic Gotu Kola + Acebutolol interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Tulsi Holy Basil Gotu Kola — through 1 ingredient. Tap an ingredient for the detail:
Krishna TulsiAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, holy basil seed oil might increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Read the full Krishna Tulsi + Acenocoumarol interactionAcepromazineAtravet
How Acepromazine interacts with Tulsi Holy Basil Gotu Kola — through 1 ingredient. Tap an ingredient for the detail:
Organic Gotu KolaCns Depressants Moderate
Interaction Summary
Theoretically, taking gotu kola might increase the sedative effects of CNS depressants.
Read the full Organic Gotu Kola + Acepromazine interactionAcetaminophenChildren's Tylenol, Children's Tylenol Meltaways, Tylenol, Tylenol Ex Strength
How Acetaminophen interacts with Tulsi Holy Basil Gotu Kola — through 1 ingredient. Tap an ingredient for the detail:
Organic Gotu KolaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking gotu kola with hepatotoxic drugs might have additive adverse effects.
Read the full Organic Gotu Kola + Acetaminophen interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Tulsi Holy Basil Gotu Kola — through 2 ingredients. Tap an ingredient for the detail:
Organic Gotu KolaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking gotu kola with hepatotoxic drugs might have additive adverse effects.
Read the full Organic Gotu Kola + Acetaminophen, Aspirin interactionKrishna TulsiAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, holy basil seed oil might increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Read the full Krishna Tulsi + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Tulsi Holy Basil Gotu Kola — through 2 ingredients. Tap an ingredient for the detail:
Krishna TulsiAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, holy basil seed oil might increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Read the full Krishna Tulsi + Acetaminophen, Aspirin, Caffeine interactionOrganic Gotu KolaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking gotu kola with hepatotoxic drugs might have additive adverse effects.
Read the full Organic Gotu Kola + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Brompheniramine, PhenylpropanolamineDimetapp Cold and Flu
How Acetaminophen, Brompheniramine, Phenylpropanolamine interacts with Tulsi Holy Basil Gotu Kola — through 1 ingredient. Tap an ingredient for the detail:
Organic Gotu KolaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking gotu kola with hepatotoxic drugs might have additive adverse effects.
Read the full Organic Gotu Kola + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionAcetaminophen, ButalbitalAxocet, Bancap, Bucet, Butex Forte, Esgic CF, Orbivan CF +5 more
How Acetaminophen, Butalbital interacts with Tulsi Holy Basil Gotu Kola — through 1 ingredient. Tap an ingredient for the detail:
Organic Gotu KolaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking gotu kola with hepatotoxic drugs might have additive adverse effects.
Read the full Organic Gotu Kola + Acetaminophen, Butalbital interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with Tulsi Holy Basil Gotu Kola — through 1 ingredient. Tap an ingredient for the detail:
Organic Gotu KolaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking gotu kola with hepatotoxic drugs might have additive adverse effects.
Read the full Organic Gotu Kola + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with Tulsi Holy Basil Gotu Kola — through 1 ingredient. Tap an ingredient for the detail:
Organic Gotu KolaHepatotoxic Drugs, Cns Depressants Moderate
Interaction Summary
Theoretically, taking gotu kola with hepatotoxic drugs might have additive adverse effects.
Read the full Organic Gotu Kola + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Butalbital, CodeineBancap w/ Codeine
How Acetaminophen, Butalbital, Codeine interacts with Tulsi Holy Basil Gotu Kola — through 1 ingredient. Tap an ingredient for the detail:
Organic Gotu KolaCns Depressants, Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking gotu kola might increase the sedative effects of CNS depressants.
Read the full Organic Gotu Kola + Acetaminophen, Butalbital, Codeine interactionAcetaminophen, Butalbital, Codeine PhosphatePhrenilin #3
How Acetaminophen, Butalbital, Codeine Phosphate interacts with Tulsi Holy Basil Gotu Kola — through 1 ingredient. Tap an ingredient for the detail:
Organic Gotu KolaHepatotoxic Drugs, Cns Depressants Moderate
Interaction Summary
Theoretically, taking gotu kola with hepatotoxic drugs might have additive adverse effects.
Read the full Organic Gotu Kola + Acetaminophen, Butalbital, Codeine Phosphate interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with Tulsi Holy Basil Gotu Kola — through 1 ingredient. Tap an ingredient for the detail:
Organic Gotu KolaCns Depressants, Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking gotu kola might increase the sedative effects of CNS depressants.
Read the full Organic Gotu Kola + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with Tulsi Holy Basil Gotu Kola — through 1 ingredient. Tap an ingredient for the detail:
Organic Gotu KolaHepatotoxic Drugs, Cns Depressants Moderate
Interaction Summary
Theoretically, taking gotu kola with hepatotoxic drugs might have additive adverse effects.
Read the full Organic Gotu Kola + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with Tulsi Holy Basil Gotu Kola — through 1 ingredient. Tap an ingredient for the detail:
Organic Gotu KolaCns Depressants, Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking gotu kola might increase the sedative effects of CNS depressants.
Read the full Organic Gotu Kola + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with Tulsi Holy Basil Gotu Kola — through 1 ingredient. Tap an ingredient for the detail:
Organic Gotu KolaHepatotoxic Drugs, Cns Depressants Moderate
Interaction Summary
Theoretically, taking gotu kola with hepatotoxic drugs might have additive adverse effects.
Read the full Organic Gotu Kola + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Caffeine, IsomethepteneMigralam
How Acetaminophen, Caffeine, Isometheptene interacts with Tulsi Holy Basil Gotu Kola — through 1 ingredient. Tap an ingredient for the detail:
Organic Gotu KolaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking gotu kola with hepatotoxic drugs might have additive adverse effects.
Read the full Organic Gotu Kola + Acetaminophen, Caffeine, Isometheptene interactionAcetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with Tulsi Holy Basil Gotu Kola — through 1 ingredient. Tap an ingredient for the detail:
Organic Gotu KolaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking gotu kola with hepatotoxic drugs might have additive adverse effects.
Read the full Organic Gotu Kola + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, Chlorpheniramine Maleate, Dextromethorphan HbrVicks Formula 44M Cough, Cold & Flu Relief
How Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interacts with Tulsi Holy Basil Gotu Kola — through 1 ingredient. Tap an ingredient for the detail:
Organic Gotu KolaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking gotu kola with hepatotoxic drugs might have additive adverse effects.
Read the full Organic Gotu Kola + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionAcetaminophen, Chlorpheniramine, Codeine, PhenylephrineColrex
How Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interacts with Tulsi Holy Basil Gotu Kola — through 1 ingredient. Tap an ingredient for the detail:
Organic Gotu KolaHepatotoxic Drugs, Cns Depressants Moderate
Interaction Summary
Theoretically, taking gotu kola with hepatotoxic drugs might have additive adverse effects.
Read the full Organic Gotu Kola + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, DextromethorphanCoricidin II Extra Strength Cold and Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan interacts with Tulsi Holy Basil Gotu Kola — through 1 ingredient. Tap an ingredient for the detail:
Organic Gotu KolaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking gotu kola with hepatotoxic drugs might have additive adverse effects.
Read the full Organic Gotu Kola + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionAcetaminophen, Chlorpheniramine, Dextromethorphan HydrobromideCoricidin HBP Maximum Strength Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interacts with Tulsi Holy Basil Gotu Kola — through 1 ingredient. Tap an ingredient for the detail:
Organic Gotu KolaHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, taking gotu kola with hepatotoxic drugs might have additive adverse effects.
Read the full Organic Gotu Kola + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Tulsi Holy Basil Gotu Kola with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
organic Gotu Kola
Cns Depressants
Theoretically, taking gotu kola might increase the sedative effects of CNS depressants.
In vitro research suggests that gotu kola may have sedative effects via binding of GABA receptors.
Hepatotoxic Drugs
Theoretically, taking gotu kola with hepatotoxic drugs might have additive adverse effects.
There are at least four case reports of hepatotoxicity associated with the use of gotu kola. However, more information is needed to determine if gotu kola was the causative factor in these cases.
organic Tulsi (Holy Basil) Blend
Anticoagulant/Antiplatelet Drugs
Theoretically, holy basil seed oil might increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
Animal research shows that holy basil seed oil can prolong bleeding time, possibly due to inhibition of platelet aggregation. However, it is not known if this occurs in humans.
Antidiabetes Drugs
Theoretically, holy basil might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Small clinical studies show that taking holy basil can decrease fasting blood glucose and other measures of glycemic control in patients with type 2 diabetes.
Pentobarbital (Nembutal)
Theoretically, holy basil seed oil might increase the sedative effects of pentobarbital.
Animal research shows that holy basil seed oil increases pentobarbitone-induced sleeping time. However, it is not known if this occurs in humans or if this applies to other barbiturates or sedatives.
Brand information
Manufacturer and brand details for Tulsi Holy Basil Gotu Kola, from the product label.
Tulsi Holy Basil Gotu Kola by Organic India: Common Questions
Does Tulsi Holy Basil Gotu Kola by Organic India interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Can I take this if I'm on blood thinners like warfarin or aspirin?
What if I take diabetes medication?
What are the side effects?
Does this actually work for anxiety or stress?
Is it safe to take long-term?
Can I use this while pregnant or breastfeeding?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Tulsi Holy Basil Gotu Kola is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Tulsi Holy Basil Gotu Kola’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Holy Basil
Interacts with 212 drugsHoly basil (tulsi) is a traditional Ayurvedic herb most often used today for stress and general wellness, but the human evidence is mostly small and preliminary. It is generally well tolerat...
Read the full Holy Basil monograph → Herb & supplement monographGotu Kola
Interacts with 579 drugsGotu kola is a traditional Ayurvedic and Asian herb that people use for wound healing, circulation, skin problems, and as a calming or memory-supporting herb. Some early studies suggest poss...
Read the full Gotu Kola monograph →Sources & How We Checked
Tulsi Holy Basil Gotu Kola's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 26 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Holy Basil 8 references
- Agrawal P, Rai V, Singh RB. Randomized placebo-controlled, single blind trial of holy basil leaves in patients with noninsulin-dependent diabetes mellitus. Int J Clin Pharmacol Ther 1996;34:406-9.
- Sakina MR, Dandiya PC, Hamdard ME, Hameed A. Preliminary psychopharmacological evaluation of Ocimum sanctum leaf extract. J Ethnopharmacol 1990;28:143-50. PubMed
- Singh S, Rehan HM, Majumdar DK. Effect of Ocimum sanctum fixed oil on blood pressure, blood clotting time and pentobarbitone-induced sleeping time. J Ethnopharmacol 2001;78:139-43. PubMed
- Mondal, S., Varma, S., Bamola, V. D., Naik, S. N., Mirdha, B. R., Padhi, M. M., Mehta, N., and Mahapatra, S. C. Double-blinded randomized controlled trial for immunomodulatory effects of Tulsi (Ocimum sanctum Linn.) leaf extract on healthy volunteers. J PubMed
- Agarwal, P. and Nagesh, L. Comparative evaluation of efficacy of 0.2% Chlorhexidine, Listerine and Tulsi extract mouth rinses on salivary Streptococcus mutans count of high school children--RCT. Contemp.Clin Trials 2011;32(6):802-808. PubMed
- Vohora, S. B., Garg, S. K., and Chaudhury, R. R. Antifertility screening of plants. 3. Effect of six indigenous plants on early pregnancy in albino rats. Indian J Med Res 1969;57(5):893-899.
- Khanna S, Gupta SR, Grover JK. Effect of long term feeding of tulsi (Ocimum sanctum Linn) on reproductive performance of adult albino rats. Indian J Exp Biol 1986;24(5):302-4.
- Somasundaram G, Manimekalai K, Salwe KJ, Pandiamunian J. Evaluation of the antidiabetic effect of Ocimum sanctum in type 2 diabetes patients. Int J Life Sci Pharma Res 2012;2(3):75-81.
Gotu Kola 18 references
- Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
- Pointel JP, Boccalon H, Cloarec M, et al. Titrated extract of Centella asiatica (TECA) in the treatment of venous insufficiency of the lower limbs. Angiol 1987;38:46-50. PubMed
- Brinkhaus B, Lindner M, Schuppan D, Hahn EG. Chemical, pharmacological and clinical profile of the east Asian medical plant Centella asiatica. Phytomedicine 2000;7:427-48.
- Eun HC, Lee AY. Contact dermatitis due to madecassol. Contact Dermatitis 1985;13:310-3.. PubMed
- Hausen BM. Centella asiatica (Indian pennywort), an effective therapeutic but a weak sensitizer. Contact Dermatitis 1993;29:175-9..
- Bilbao I, Aguirre A, Zabala R, et al. Allergic contact dermatitis from butoxyethyl nicotinic acid and Centella asiatica extract. Contact Dermatitis 1995;33:435-6.
- Cesarone MR, Incandela L, De Sanctis MT, et al. Evaluation of treatment of diabetic microangiopathy with total triterpenic fraction of Centella asiatica: a clinical prospective randomized trial with a microcirculatory model. Angiology 2001;52 Suppl 2 DOI
- Bradwejn J, Zhou Y, Koszycki D, Shlik J. A double-blind, placebo-controlled study on the effects of Gotu Kola (Centella asiatica) on acoustic startle response in healthy subjects. J Clin Psychopharmacol 2000;20:680-4. PubMed
- Young GL, Jewell D. Creams for preventing stretch marks in pregnancy. Cochrane Database Syst Rev 2000;(2):CD000066. PubMed
- Jorge OA, Jorge AD. Hepatotoxicity associated with the ingestion of Centella asiatica. Rev Esp Enferm Dig 2005;97:115-24. PubMed
- Mallol J, Belda MA, Costa D, et al. Prophylaxis of striae gravidarum with a topical formulation. A double blind trial. Int J Cosmet Sci 1991;3:51-7.
- Izu, R., Aguirre, A., Gil, N., and Diaz-Perez, J. L. Allergic contact dermatitis from a cream containing Centella asiatica extract. Contact Dermatitis 1992;26(3):192-193.
- Santucci, B., Picardo, M., and Cristaudo, A. Contact dermatitis due to Centelase. Contact Dermatitis 1985;13(1):39. PubMed
- Vena, G. A. and Angelini, G. Contact allergy to Centelase. Contact Dermatitis 1986;15(2):108-109. PubMed
- Marastoni, F., Baldo, A., Redaelli, G., and Ghiringhelli, L. [Centella asiatica extract in venous pathology of the lower limbs and its evaluation as compared with tribenoside]. Minerva Cardioangiol. 1982;30(4):201-207.
- Danese, P., Carnevali, C., and Bertazzoni, M. G. Allergic contact dermatitis due to Centella asiatica extract. Contact Dermatitis 1994;31(3):201.
- Bilbao, I., Aguirre, A., Zabala, R., Gonzalez, R., Raton, J., and Diaz Perez, J. L. Allergic contact dermatitis from butoxyethyl nicotinic acid and Centella asiatica extract. Contact Dermatitis 1995;33(6):435-436.
- Dantuluri S, North-lewis P, Karthik SV. Gotu Kola induced hepatotoxicity in a child - need for caution with alternative remedies. Dig Liver Dis. 2011;43(6):500. PubMed
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
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