Interactions on record — worth a quick check against your medications. Based on 2 of 4 ingredients. Check your meds →
Dietary supplement

Essential Female Ingredients & Drug Interactions

by Organic India

Capsule Category: Botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Essential Female is a dietary supplement by Organic India with 4 active ingredients. Its ingredients are commonly taken for women's reproductive health, promoting breast milk supply, digestive complaints.Based on those ingredients, 674 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are organic Guduchi, Shatavari. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Essential Female by Organic India

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 4 of its 4 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

Essential Female contains 4 active ingredients: Shatavari (Asparagus racemosus), organic Guduchi (Tinospora cordifolia), organic Vana Tulsi, and Lodhra. These are traditional Ayurvedic plants used to support female reproductive and hormonal health.

The capsules themselves are made from organic vegetable pullulan, an inactive ingredient that serves as the capsule shell.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: hormonal balance and reproductive system health.
  • We looked for evidence on: Lactation, Sexual desire, menopausal symptoms, menstrual health.
  • The closest evidence on file: Tinospora Cordifolia is rated "Insufficient Reliable Evidence To Rate" for Sexual desire (Natural Medicines).
  • Also on file: Asparagus Racemosus is rated "Insufficient Reliable Evidence To Rate" for Lactation, Sexual desire.

Evidence for these ingredients is limited. Guduchi is possibly effective for type 2 diabetes, based on clinical research showing it can lower fasting blood sugar.

For Shatavari, the data we hold shows insufficient evidence to rate its effects on lactation, muscle strength, sexual desire, tuberculosis, and bronchitis — meaning we don't yet have reliable research backing its traditional uses. No effectiveness rating is established in our data for Vana Tulsi or Lodhra.

The evidence, ingredient by ingredient Asparagus Racemosus Tinospora Cordifolia

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Shatavari is generally well tolerated in traditional use, but high-quality safety data are limited. Safety during pregnancy is not well established, so it's best avoided unless your doctor advises otherwise.

It's traditionally used to support milk supply, but reliable safety data are lacking — use it while breastfeeding only under professional guidance. Guduchi is also generally well tolerated by mouth, with the most common side effects being headache and nasal pain.

However, liver injury has been reported — in one series of cases, 49 patients developed autoimmune hepatitis, acute hepatitis, or acute liver failure after taking Guduchi alone or in combination products over 42–90 days; 2 required transplants and 4 died. Safety during pregnancy is not well established, so it's best avoided.

It should not be used while breastfeeding due to insufficient safety information. No safety data is on file for Vana Tulsi or Lodhra.

Side effects, ingredient by ingredient Asparagus Racemosus Tinospora Cordifolia

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 2 matched ingredients can interact with medications — Tinospora Cordifolia, Asparagus Racemosus.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: immunosuppressants / transplant drugs; diabetes medications; lithium.
  • For scale: 674 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your doctor or pharmacist before taking this product if you use immunosuppressants, antidiabetes drugs, diuretics, or lithium (all Moderate interactions). Additionally, confirm any medications your liver breaks down — including certain antidepressants, blood thinners, and heart drugs — since Guduchi may raise their levels.

No interactions are documented for Vana Tulsi and Lodhra, as we hold no data for them.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

Essential Female is designed for female hormonal and reproductive support using traditional Ayurvedic ingredients, though evidence is limited for most of them. If you take any medications — especially immunosuppressants, diabetes drugs, diuretics, lithium, or drugs your liver breaks down — you need to check them against this product before starting.

Talk with your doctor or pharmacist about whether it's right for you, particularly if you're pregnant, breastfeeding, or have liver concerns.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jul 21, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Essential Female, straight from the product label.

Brand Organic India
Barcode (UPC) 801541519323
Net contents 90 Veg Cap(s)
Market status On market
Date entered into DSLD Jul 21, 2022
DSLD ID 268093
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Kosher, Organic, Adult Female (18 - 50 Years), Halal
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Essential Female by Organic India, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
45
UPC/BARCODE
801541519323
IngredientAmount% DV
Shatavari530 mg--
organic Guduchi90 mg--
organic Vana Tulsi50 mg--
Lodhra30 mg--

Other ingredients: organic Vegetable Pullulan Capsules

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

At the heart of organic India is our commitment to be a living embodiment of love and consciousness in action. Whole herb solutions grown sustainably by small family farmers using regenerative organic agriculture. Healthy conscious living

Mfg. Lic. No. A-2755

For export to USA only

Formulation

Essential Female is a nourishing tonic for maintaining a healthy reproductive system. Promoting hormonal balance and vitality, this unique formula contains ancient Ayurvedic herbs to support women through all stages of life.

Vegan - Vegetarian

Gluten free

Hormonal balance

USDA Organic Product produced and processed according to NPOP standard of India & USDA-NOP www.controlunion.com

Product of India

Formula

Promoting hormonal balance and vitality, this unique formula contains ancient Ayurvedic herbs to support women through all stages of life.

OU Kosher

Halal Mumbai India Halal Committee Registration No. 0854

Suggested/Recommended/Usage/Directions

Suggested Use: 2 capsules with food and water twice daily, not to exceed 6 capsules per day.

Precautions

Do not use if pregnant or nursing without consulting a physician.

Warning: Reproductive Harm - www.P65Warnings.ca.gov

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

FDA Statement of Identity

Herbal Supplement

Seals/Symbols

USDA Organic Non GMO Project Verified nongmoproject.org Certified B Corporation Control Union Certified NPOP/NAB/0010 Certified Organic by Control Union-CU801983

Halal Mumbai India Halal Committee Registration No. 0854 OU Kosher

See for yourself

Essential Female by Organic India label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Essential Female by Organic India

These are the 4 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container45 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Shatavari

Interacts with
76 drugs
530 mg per serving

Asparagus racemosus, often called shatavari, is an Ayurvedic herb traditionally used to support women's health, digestion, and overall vitality. Human...

Shatavari monograph & interactions

Organic Guduchi

Interacts with
612 drugs
90 mg per serving

Tinospora cordifolia, known as Guduchi or Giloy in Ayurvedic medicine, is a climbing plant traditionally used to support immunity and treat fevers. Ea...

Organic Guduchi monograph & interactions

Organic Vana Tulsi

50 mg per serving

Lodhra

30 mg per serving Form: Symplocos racemosa

Other (inactive) ingredients: Organic Vegetable Pullulan Capsules. These complete the product’s ingredient list but are not active constituents.

Interaction report

Essential Female by Organic India Drug Interactions

Want to check YOUR meds against Essential Female?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
674Drugs
674 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Essential Female with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

organic Guduchi6 drug types · 612 drugs

Antidiabetes Drugs

Theoretically, Tinospora cordifolia might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Clinical research in adults with type 2 diabetes shows that Tinospora cordifolia can reduce fasting blood glucose and glycated hemoglobin. Additionally, animal research shows that Tinospora cordifolia has hypoglycemic effects.

Likelihood Possible Evidence A
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, Tinospora cordifolia might increase levels of drugs metabolized by CYP1A2.
In vitro research shows that Tinospora cordifolia extract inhibits CYP1A2 at high concentrations. However, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2C19 (Cyp2C19) Substrates

Theoretically, Tinospora cordifolia might increase levels of drugs metabolized by CYP2C19.
In vitro research shows that Tinospora cordifolia extract inhibits CYP2C19 at high concentrations. However, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2C9 (Cyp2C9) Substrates

Theoretically, Tinospora cordifolia might increase levels of drugs metabolized by CYP2C9.
In vitro research shows that Tinospora cordifolia extract inhibits CYP2C9. Animal research shows that Tinospora cordifolia extract 400 mg/kg twice daily for 14 days reduces the clearance and increases plasma levels of glyburide, a CYP2C9 substrate. However, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2D6 (Cyp2D6) Substrates

Theoretically, Tinospora cordifolia might increase levels of drugs metabolized by CYP2D6.
In vitro research shows that Tinospora cordifolia extract inhibits CYP2D6 at high concentrations. However, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, Tinospora cordifolia might reduce the effectiveness of immunosuppressants.
In vitro and animal research shows that Tinospora cordifolia has immunostimulant effects.

Likelihood Possible Evidence D

Shatavari2 drug types · 76 drugs

Diuretic Drugs

Theoretically, asparagus racemosus root might increase diuresis and electrolyte loss when used with diuretic drugs.
Animal studies show that asparagus racemosus root has diuretic effects when used in high doses. This effect has not been reported in humans.

Likelihood Possible Evidence D
Lithium

Theoretically, Asparagus racemosus root could reduce excretion and increase levels of lithium.
Animal research suggests that Asparagus racemosus root has diuretic properties when used in high doses. Therefore, it might reduce excretion and increase levels of lithium. The dose of lithium might need to be decreased.

Likelihood Probable Evidence D
The maker

Brand information

Manufacturer and brand details for Essential Female, from the product label.

Organic India

See all Organic India products
Name
Organic India Pvt. Ltd.
Street Address
Factory: C-5/10, Agro Park Phase -II UPSIDC Industrial Area, Kursi Road
City
Barabanki
State
U.P.
ZipCode
225302
Pharmacist Counseling Corner

Essential Female by Organic India: Common Questions

Does Essential Female by Organic India interact with any medications?
Yes. Based on its ingredients, Essential Female has a known interaction with 674 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Essential Female contains 4 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this while breastfeeding?
Shatavari is traditionally used to support milk supply, but reliable safety data are lacking — use it only under professional guidance. Guduchi should not be used while breastfeeding due to insufficient safety information. Talk with your doctor or pharmacist about whether this product is right for you.
Is this safe in pregnancy?
Safety during pregnancy is not well established for either Shatavari or Guduchi, so both are best avoided unless your doctor advises otherwise. Discuss this product with your doctor before taking it if you're pregnant or planning to become pregnant.
Can Guduchi help with diabetes?
Guduchi is possibly effective for type 2 diabetes — clinical research shows it can lower fasting blood sugar. However, it may also increase the risk of low blood sugar if you're taking diabetes medications, so you'll need to check with your doctor or pharmacist before combining them.
What are the side effects?
Guduchi is generally well tolerated, with the most common side effects being headache and nasal pain. Liver injury is rare but serious — it's been reported in patients who took Guduchi products for 42–90 days. Shatavari has limited safety data, so side effects aren't fully documented.
Does this contain any fillers?
The capsule itself is made from organic vegetable pullulan, which is an inactive ingredient that serves as the capsule shell. There are no other listed inactive ingredients.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Essential Female is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Essential Female label
Sources

Sources & How We Checked

Essential Female's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 17 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Asparagus Racemosus 1 reference
  1. Satish Kumar MC, Udupa AL, Sammodavardhana K, Rathnakar UP, Shvetha U, Kodancha GP. Acute toxicity and diuretic studies of the roots of Asparagus racemosus Willd in rats. West Indian Med J. 2010;59(1):3-6.

See these in context on the Asparagus Racemosus monograph →

Tinospora Cordifolia 16 references
  1. Stanely Mainzen Prince P, Menon VP. Hypoglycaemic and hypolipidaemic action of alcohol extract of Tinospora cordifolia roots in chemical induced diabetes in rats. Phytother Res 2003;17:410-3.
  2. Grover JK, Vats V, Rathi SS. Anti-hyperglycemic effect of Eugenia jambolana and Tinospora cordifolia in experimental diabetes and their effects on key metabolic enzymes involved in carbohydrate metabolism. J Ethnopharmacol 2000;73:461-70. PubMed
  3. Manjrekar PN, Jolly CI, Narayanan S. Comparative studies of the immunomodulatory activity of Tinospora cordifolia and Tinospora sinensis. Fitoterapia 2000;71:254-7. PubMed
  4. Prince PS, Menon VP. Antioxidant activity of Tinospora cordifolia roots in experimental diabetes. J Ethnopharmacol 1999;65:277-81. PubMed
  5. Stanely Mainzen Prince P, Menon VP, Gunasekaran G. Hypolipidaemic action of Tinospora cordifolia roots in alloxan diabetic rats. J Ethnopharmacol 1999;64:53-7. PubMed
  6. Badar VA, Thawani VR, Wakode PT, et al. Efficacy of Tinospora cordifolia in allergic rhinitis. J Ethnopharmacol 2005;96:445-9. PubMed
  7. Kapil A, Sharma S. Immunopotentiating compounds from Tinospora cordifolia. J Ethnopharmacol 1997;58:89-95. PubMed
  8. Nair PK, Rodriguez S, Ramachandran R, et al. Immune stimulating properties of a novel polysaccharide from the medicinal plant Tinospora cordifolia. Int Immunopharmacol 2004;4:1645-59. PubMed
  9. Castillo AL, Osi MO, Ramos JD, De Francia JL, Dujunco MU, Quilala PF. Efficacy and safety of Tinospora cordifolia lotion in Sarcoptes scabiei var hominis-infected pediatric patients: A single blind, randomized controlled trial. J Pharmacol Pharmacother. 2 PubMed
  10. Sahu R, Ahmed T, Sangana R, Punde R, Subudhi BB. Effect of Tinospora cordifolia aqua-alcoholic extract on pharmacokinetic of glibenclamide in rat: an herb-drug interaction study. J Pharm Biomed Anal. 2018;151:310-6. doi: 10.1016/j.jpba.2018.01.010. PubMed
  11. Patial V, Katoch S, Chhimwal J, Singh PP, Suresh PS, Padwad Y. Tinospora cordifolia activates PPAR? pathway and mitigates glomerular and tubular cell injury in diabetic kidney disease. Phytomedicine 2021;91:153663. PubMed
  12. Kulkarni AV, Hanchanale P, Prakash V, et al. Tinospora Cordifolia (Giloy)-Induced Liver Injury During the COVID-19 Pandemic-Multicenter Nationwide Study From India. Hepatol Commun 2022;6(6):1289-1300. PubMed
  13. Nagral A, Adhyaru K, Rudra OS, Gharat A, Bhandare S. Herbal Immune Booster-Induced Liver Injury in the COVID-19 Pandemic - A Case Series. J Clin Exp Hepatol. 2021;11(6):732-738. PubMed
  14. Chattopadhyay K, Wang H, Kaur J, et al. Effectiveness and Safety of Ayurvedic Medicines in Type 2 Diabetes Mellitus Management: A Systematic Review and Meta-Analysis. Front Pharmacol. 2022;13:821810. Published 2022 Jun 8. PubMed
  15. Nnamani I, Tolu-Akinnawo O, Dufera RR, Akintunde A, Maliakkal B. Tinospora cordifolia (Guduchi/Giloy)-Induced Liver Injury: A Case Review. Cureus 2023;15(5):e39793. PubMed
  16. May K, Jeitler M, Murthy V, Stapelfeldt E, Kessler CS. A Case Report of Acute Hepatitis Involving the Medicinal Herb Tinospora cordifolia Along with Other Variables. J Integr Complement Med 2023;29(5):327-333.

See these in context on the Tinospora Cordifolia monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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