Essiactive Tea Capsules Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Essiactive Tea Capsules against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Essiactive Tea Capsules is a dietary supplement by Zazzee Naturals with 4 active ingredients. Its ingredients are commonly taken for skin conditions like acne and eczema, digestive support, diuretic ('detox') and blood purifier.Based on those ingredients, 2,130 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Slippery Elm bark extract, Turkey Rhubarb Root Extract, Sheep Sorrel Plant Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Essiactive Tea Capsules by Zazzee Naturals
Ask about any prescription or over-the-counter medication and we check it for interactions with Essiactive Tea Capsules by Zazzee Naturals — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Essiactive Tea Capsules by Zazzee Naturals
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
Essiactive Tea Capsules contains 4 active ingredients: burdock root extract, slippery elm bark extract, sheep sorrel plant extract, and turkey rhubarb root extract, supplied in a proprietary blend. The capsules also contain inactive ingredients—cellulose, rice powder, and silica—which serve as fillers and binders.
Burdock has been used traditionally for skin health. Slippery elm bark is traditionally taken for digestive comfort.
Sheep sorrel and turkey rhubarb root are both known for their traditional digestive roles, with rhubarb root having mild laxative properties.
Does it work?
Moderate evidence
The evidence base for most of these ingredients is limited. For burdock root, we have insufficient reliable evidence to rate its use for acne, aging skin, breast cancer, common cold, or eczema.
Slippery elm also lacks sufficient evidence for cancer, constipation, cough, inflammatory bowel disease, or diarrhea. Sheep sorrel likewise shows insufficient evidence for bronchitis, breast cancer, or rhinosinusitis.
Turkey rhubarb root fares somewhat better: it is rated possibly effective for pancreatitis and menopausal symptoms. However, it has insufficient evidence for appendicitis, nasopharyngeal cancer, nonalcoholic fatty liver disease, or constipation.
In summary, if you're looking for proven benefits, the evidence isn't established in our data for most of the conditions these ingredients are traditionally used for.
How safe is it?
Well-documented data
Burdock is likely safe as a food and for short-term use in healthy adults, though human safety data are limited. It's generally well tolerated when eaten as food, but rare allergic reactions—including contact dermatitis and anaphylaxis—have been reported.
A rare case of drug-induced liver injury occurred after one month of use in a detox tea blend, though it's unclear if burdock alone was responsible. Slippery elm is generally well tolerated for short-term use, though high-quality safety data are limited.
Contact dermatitis and hives have occurred after exposure to slippery elm pollen or bark. Sheep sorrel is generally safe in food amounts, but its high oxalate content can be a concern with large or concentrated doses; a rare case of kidney inflammation was reported in a child after consuming wild sorrel.
Turkey rhubarb root is well tolerated in food amounts and medicinal doses, with the most common side effects being cramps, diarrhea, and nausea. Chronic overuse can cause electrolyte loss, kidney problems, and (very rarely) anaphylaxis.
For pregnancy: burdock should be avoided in medicinal amounts due to possible uterine effects; sheep sorrel is possibly safe but data are limited; rhubarb root is possibly unsafe and should be avoided. For breastfeeding: burdock and slippery elm lack sufficient safety data and should be avoided in medicinal use; sheep sorrel and rhubarb should be avoided because laxative compounds may pass into milk.
Meds to double-check
Moderate interaction found
Before taking Essiactive Tea Capsules, check with your doctor or pharmacist if you take blood thinners or antiplatelet drugs (warfarin, aspirin), kidney-damaging medications, liver-damaging medications, corticosteroids, diuretics (water pills), other laxatives, digoxin, cyclosporine, or fexofenadine—or any other oral medications, since slippery elm may slow their absorption. Altogether, these interactions span 2,131 individual medications.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
This product combines four botanical extracts with limited evidence of effectiveness and several important interactions with common medications—particularly blood thinners, kidney-damaging drugs, heart medications, and diuretics. If you take any prescription medications, especially for heart, kidney, blood clotting, or immune function, talk with your doctor or pharmacist before starting this supplement.
Pregnant or breastfeeding individuals should not take medicinal amounts of this product.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 4 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Oct 24, 2022.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Essiactive Tea Capsules, straight from the product label.
| Brand | Zazzee Naturals |
|---|---|
| Barcode (UPC) | X001CG5M41 |
| Net contents | 180 Veggie Cap(s) |
| Market status | On market |
| Date entered into DSLD | Oct 24, 2022 |
| DSLD ID | 276085 |
| Product type | Botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free, Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Essiactive Tea Capsules by Zazzee Naturals, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Proprietary Blend | 500 mg | -- |
| Burdock root extract | 0 NP | -- |
| Slippery Elm bark extract | 0 NP | -- |
| Sheep Sorrel Plant Extract | 0 NP | -- |
| Turkey Rhubarb Root Extract | 0 NP | -- |
Other ingredients: Cellulose, Rice, Powder, Silica
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Suggested Usage: Take 1 capsule 1 to 2 times daily, preferably 1 hour before meals, or as recommended by your healthcare practitioner.
Formula
Zazzee Natural Essiactive is a concentrated blend of herbs made according to a world renowned traditional Native American herbal formula. Zazzee Naturals Essiactive contains high quality herbal extracts concentrated at a 4:1 ratio for maximum potency. Essiactive provides natural support for cell repair, detoxification, and a healthy immune system.
500 mg per capsule
Precautions
Warnings: For adults only.
Do not exceed recommended dosage. Not for long-term use. Read and follow directions carefully. Do not use if you have or develop diarrhea, loose stools, or abdominal pain because rhubarb root may worsen these conditions and be harmful to your health.
Consult your physician if you have frequent diarrhea or if you are pregnant or nursing, taking medication, or have a medical condition.
Keep out of reach of children.
Allergen Information: Not manufactured with yeast, wheat, gluten, soy, corn, milk, egg, fish, shellfish or tree nut ingredients. Produced in a GMP facility that processes other ingredients containing these allergens.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Formulation
Supports a healthy immune system Supports detoxification and healthy cell repair 4:1 extracts for maximum strength dosage
Allergen Information: Not manufactured with yeast, wheat, gluten, soy, corn, milk, egg, fish, shellfish or tree nut ingredients.
Natural color variation may occur in this product.
Made with non GMO ingredients
FDA Statement of Identity
Dietary Supplement
Storage
Store in a cool, dry place after opening.
General Statements
Please recycle.
Seals/Symbols
GMP Good Manufacturing Practice Consistent Quality Made in USA
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Essiactive Tea Capsules by Zazzee Naturals label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Essiactive Tea Capsules by Zazzee Naturals
These are the 4 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Veggie Capsule(s) Dosage formCapsule Servings per container180 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Proprietary Blend
Other (inactive) ingredients: Cellulose, Rice, Powder, Silica. These complete the product’s ingredient list but are not active constituents.
Essiactive Tea Capsules by Zazzee Naturals Drug Interactions
HelloPharmacist Interaction Report
Essiactive Tea Capsules by Zazzee Naturals contains four active ingredients, and three of them—burdock root extract, sheep sorrel plant extract, and turkey rhubarb root extract—interact with medications.
The most serious documented interaction is with turkey rhubarb root extract and nephrotoxic drugs (kidney-damaging medications), where long-term use of rhubarb's anthraquinone compounds might increase kidney damage risk.
Read the full breakdown — every affected drug type, severity by severity
Burdock root and sheep sorrel both interact with blood thinners and antiplatelet drugs (such as warfarin and aspirin) at a Moderate severity level—theoretically raising bleeding risk, though this hasn't been reported in humans. Sheep sorrel also affects how your body absorbs certain medications through OATP transporters in the gut, potentially reducing the effectiveness of drugs like fexofenadine (Allegra) and others in that class.
Turkey rhubarb root extract carries multiple Moderate interactions: with liver-damaging drugs (hepatotoxic drugs), water pills and steroid medications (both risk potassium loss), other laxatives, warfarin, digoxin (a heart medication), and cyclosporine (an immunosuppressant). Slippery elm bark extract has a Moderate interaction with oral medications in general—its mucilage may slow drug absorption and lower blood levels.
Although we hold no interaction data for the Proprietary Blend container itself, we encourage you to check your exact medications with the search tool on this page.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Essiactive Tea Capsules?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Essiactive Tea Capsules interact with 2,130 drugs. Click any drug to see the details.
4 of the 4 ingredients in Essiactive Tea Capsules interact with drugs. Each result below shows which ingredient is responsible. Slippery Elm bark extract Turkey Rhubarb Root Extract Sheep Sorrel Plant Extract Burdock root extract
"phentolamineOraVerse, Rogitine, Ryzumvi
How "phentolamine interacts with Essiactive Tea Capsules — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Bark Extract + "phentolamine interaction6-mercaptopurinePurinethol
How 6-mercaptopurine interacts with Essiactive Tea Capsules — through 2 ingredients. Tap an ingredient for the detail:
Slippery Elm Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Bark Extract + 6-mercaptopurine interactionTurkey Rhubarb Root ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use of rhubarb with potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Turkey Rhubarb Root Extract + 6-mercaptopurine interactionAbacavirZiagen
How Abacavir interacts with Essiactive Tea Capsules — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Bark Extract + Abacavir interactionAbacavir Sulfate, Dolutegravir, LamivudineTriumeq
How Abacavir Sulfate, Dolutegravir, Lamivudine interacts with Essiactive Tea Capsules — through 2 ingredients. Tap an ingredient for the detail:
Turkey Rhubarb Root ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use of rhubarb with potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Turkey Rhubarb Root Extract + Abacavir Sulfate, Dolutegravir, Lamivudine interactionSlippery Elm Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Bark Extract + Abacavir Sulfate, Dolutegravir, Lamivudine interactionAbacavir, LamivudineEpzicom
How Abacavir, Lamivudine interacts with Essiactive Tea Capsules — through 2 ingredients. Tap an ingredient for the detail:
Turkey Rhubarb Root ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use of rhubarb with potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Turkey Rhubarb Root Extract + Abacavir, Lamivudine interactionSlippery Elm Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Bark Extract + Abacavir, Lamivudine interactionAbciximabReoPro
How Abciximab interacts with Essiactive Tea Capsules — through 3 ingredients. Tap an ingredient for the detail:
Slippery Elm Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Bark Extract + Abciximab interactionSheep Sorrel Plant ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, sorrel might cause additive effects and side effects when used with anticoagulant or antiplatelet drugs.
Read the full Sheep Sorrel Plant Extract + Abciximab interactionBurdock Root ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking burdock with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Burdock Root Extract + Abciximab interactionAbemaciclibVerzenio
How Abemaciclib interacts with Essiactive Tea Capsules — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Bark Extract + Abemaciclib interactionAbiraterone
How Abiraterone interacts with Essiactive Tea Capsules — through 2 ingredients. Tap an ingredient for the detail:
Slippery Elm Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Bark Extract + Abiraterone interactionTurkey Rhubarb Root ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use of rhubarb with potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Turkey Rhubarb Root Extract + Abiraterone interactionAbiraterone AcetateYonsa, Zytiga
How Abiraterone Acetate interacts with Essiactive Tea Capsules — through 2 ingredients. Tap an ingredient for the detail:
Turkey Rhubarb Root ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use of rhubarb with potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Turkey Rhubarb Root Extract + Abiraterone Acetate interactionSlippery Elm Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Bark Extract + Abiraterone Acetate interactionAbrocitinibCibinqo
How Abrocitinib interacts with Essiactive Tea Capsules — through 3 ingredients. Tap an ingredient for the detail:
Burdock Root ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking burdock with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Burdock Root Extract + Abrocitinib interactionSheep Sorrel Plant ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, sorrel might cause additive effects and side effects when used with anticoagulant or antiplatelet drugs.
Read the full Sheep Sorrel Plant Extract + Abrocitinib interactionSlippery Elm Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Bark Extract + Abrocitinib interactionAcalabrutinibCalquence
How Acalabrutinib interacts with Essiactive Tea Capsules — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Bark Extract + Acalabrutinib interactionAcamprosateCampral
How Acamprosate interacts with Essiactive Tea Capsules — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Bark Extract + Acamprosate interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Essiactive Tea Capsules — through 2 ingredients. Tap an ingredient for the detail:
Slippery Elm Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Bark Extract + Acarbose interactionTurkey Rhubarb Root ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use of rhubarb with potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Turkey Rhubarb Root Extract + Acarbose interactionAcebutololRhotral, Sectral
How Acebutolol interacts with Essiactive Tea Capsules — through 2 ingredients. Tap an ingredient for the detail:
Turkey Rhubarb Root ExtractHepatotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use of rhubarb with potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Turkey Rhubarb Root Extract + Acebutolol interactionSlippery Elm Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Bark Extract + Acebutolol interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Essiactive Tea Capsules — through 3 ingredients. Tap an ingredient for the detail:
Slippery Elm Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Bark Extract + Acenocoumarol interactionSheep Sorrel Plant ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, sorrel might cause additive effects and side effects when used with anticoagulant or antiplatelet drugs.
Read the full Sheep Sorrel Plant Extract + Acenocoumarol interactionBurdock Root ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking burdock with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Burdock Root Extract + Acenocoumarol interactionAcepromazineAtravet
How Acepromazine interacts with Essiactive Tea Capsules — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Bark Extract + Acepromazine interactionAcetaminophenChildren's Tylenol, Children's Tylenol Meltaways, Tylenol, Tylenol Ex Strength
How Acetaminophen interacts with Essiactive Tea Capsules — through 2 ingredients. Tap an ingredient for the detail:
Slippery Elm Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Bark Extract + Acetaminophen interactionTurkey Rhubarb Root ExtractNephrotoxic Drugs, Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, long-term use of anthraquinones from rhubarb might increase the risk of nephrotoxicity when used with nephrotoxic drugs.
Read the full Turkey Rhubarb Root Extract + Acetaminophen interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Essiactive Tea Capsules — through 4 ingredients. Tap an ingredient for the detail:
Turkey Rhubarb Root ExtractHepatotoxic Drugs, Nephrotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use of rhubarb with potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Turkey Rhubarb Root Extract + Acetaminophen, Aspirin interactionBurdock Root ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking burdock with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Burdock Root Extract + Acetaminophen, Aspirin interactionSheep Sorrel Plant ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, sorrel might cause additive effects and side effects when used with anticoagulant or antiplatelet drugs.
Read the full Sheep Sorrel Plant Extract + Acetaminophen, Aspirin interactionSlippery Elm Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Bark Extract + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Essiactive Tea Capsules — through 4 ingredients. Tap an ingredient for the detail:
Slippery Elm Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Bark Extract + Acetaminophen, Aspirin, Caffeine interactionSheep Sorrel Plant ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, sorrel might cause additive effects and side effects when used with anticoagulant or antiplatelet drugs.
Read the full Sheep Sorrel Plant Extract + Acetaminophen, Aspirin, Caffeine interactionTurkey Rhubarb Root ExtractHepatotoxic Drugs, Nephrotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use of rhubarb with potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Turkey Rhubarb Root Extract + Acetaminophen, Aspirin, Caffeine interactionBurdock Root ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, taking burdock with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Burdock Root Extract + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Brompheniramine, PhenylpropanolamineDimetapp Cold and Flu
How Acetaminophen, Brompheniramine, Phenylpropanolamine interacts with Essiactive Tea Capsules — through 2 ingredients. Tap an ingredient for the detail:
Turkey Rhubarb Root ExtractNephrotoxic Drugs, Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, long-term use of anthraquinones from rhubarb might increase the risk of nephrotoxicity when used with nephrotoxic drugs.
Read the full Turkey Rhubarb Root Extract + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionSlippery Elm Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Bark Extract + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionAcetaminophen, ButalbitalAxocet, Bancap, Bucet, Butex Forte, Esgic CF, Orbivan CF +5 more
How Acetaminophen, Butalbital interacts with Essiactive Tea Capsules — through 2 ingredients. Tap an ingredient for the detail:
Slippery Elm Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Bark Extract + Acetaminophen, Butalbital interactionTurkey Rhubarb Root ExtractHepatotoxic Drugs, Nephrotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use of rhubarb with potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Turkey Rhubarb Root Extract + Acetaminophen, Butalbital interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with Essiactive Tea Capsules — through 2 ingredients. Tap an ingredient for the detail:
Turkey Rhubarb Root ExtractNephrotoxic Drugs, Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, long-term use of anthraquinones from rhubarb might increase the risk of nephrotoxicity when used with nephrotoxic drugs.
Read the full Turkey Rhubarb Root Extract + Acetaminophen, Butalbital, Caffeine interactionSlippery Elm Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Bark Extract + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with Essiactive Tea Capsules — through 2 ingredients. Tap an ingredient for the detail:
Slippery Elm Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Bark Extract + Acetaminophen, Butalbital, Caffeine, Codeine interactionTurkey Rhubarb Root ExtractHepatotoxic Drugs, Nephrotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use of rhubarb with potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Turkey Rhubarb Root Extract + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Butalbital, CodeineBancap w/ Codeine
How Acetaminophen, Butalbital, Codeine interacts with Essiactive Tea Capsules — through 2 ingredients. Tap an ingredient for the detail:
Turkey Rhubarb Root ExtractNephrotoxic Drugs, Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, long-term use of anthraquinones from rhubarb might increase the risk of nephrotoxicity when used with nephrotoxic drugs.
Read the full Turkey Rhubarb Root Extract + Acetaminophen, Butalbital, Codeine interactionSlippery Elm Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Bark Extract + Acetaminophen, Butalbital, Codeine interactionAcetaminophen, Butalbital, Codeine PhosphatePhrenilin #3
How Acetaminophen, Butalbital, Codeine Phosphate interacts with Essiactive Tea Capsules — through 2 ingredients. Tap an ingredient for the detail:
Turkey Rhubarb Root ExtractHepatotoxic Drugs, Nephrotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use of rhubarb with potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Turkey Rhubarb Root Extract + Acetaminophen, Butalbital, Codeine Phosphate interactionSlippery Elm Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Bark Extract + Acetaminophen, Butalbital, Codeine Phosphate interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with Essiactive Tea Capsules — through 2 ingredients. Tap an ingredient for the detail:
Turkey Rhubarb Root ExtractHepatotoxic Drugs, Nephrotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use of rhubarb with potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Turkey Rhubarb Root Extract + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionSlippery Elm Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Bark Extract + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with Essiactive Tea Capsules — through 2 ingredients. Tap an ingredient for the detail:
Slippery Elm Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Bark Extract + Acetaminophen, Caffeine, Codeine interactionTurkey Rhubarb Root ExtractNephrotoxic Drugs, Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, long-term use of anthraquinones from rhubarb might increase the risk of nephrotoxicity when used with nephrotoxic drugs.
Read the full Turkey Rhubarb Root Extract + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with Essiactive Tea Capsules — through 2 ingredients. Tap an ingredient for the detail:
Turkey Rhubarb Root ExtractHepatotoxic Drugs, Nephrotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use of rhubarb with potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Turkey Rhubarb Root Extract + Acetaminophen, Caffeine, Codeine, Salicylamide interactionSlippery Elm Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Bark Extract + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with Essiactive Tea Capsules — through 2 ingredients. Tap an ingredient for the detail:
Turkey Rhubarb Root ExtractHepatotoxic Drugs, Nephrotoxic Drugs Moderate
Interaction Summary
Theoretically, concomitant use of rhubarb with potentially hepatotoxic drugs might increase the risk of developing liver damage.
Read the full Turkey Rhubarb Root Extract + Acetaminophen, Caffeine, Dihydrocodeine interactionSlippery Elm Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Bark Extract + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Caffeine, IsomethepteneMigralam
How Acetaminophen, Caffeine, Isometheptene interacts with Essiactive Tea Capsules — through 2 ingredients. Tap an ingredient for the detail:
Slippery Elm Bark ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Bark Extract + Acetaminophen, Caffeine, Isometheptene interactionTurkey Rhubarb Root ExtractNephrotoxic Drugs, Hepatotoxic Drugs Moderate
Interaction Summary
Theoretically, long-term use of anthraquinones from rhubarb might increase the risk of nephrotoxicity when used with nephrotoxic drugs.
Read the full Turkey Rhubarb Root Extract + Acetaminophen, Caffeine, Isometheptene interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Essiactive Tea Capsules with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Slippery Elm bark extract
Oral Drugs
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Slippery elm inner bark contains mucilage, which may interfere with the absorption of orally administered drugs.
Turkey Rhubarb Root Extract
Corticosteroids
Theoretically, frequent and high doses of rhubarb might increase the risk of hypokalemia when taken with corticosteroids.
Rhubarb has stimulant laxative effects. Overuse of rhubarb might compound corticosteroid-induced potassium loss.
Cyclosporine (Neoral, Sandimmune)
Theoretically, taking rhubarb with cyclosporine might reduce cyclosporine levels.
Animal research shows that co-administration of rhubarb decoction 0.25 or 1 gram/kg with cyclosporine 2.5 mg/kg, decreases cyclosporine maximum plasma concentration and overall exposure levels when compared with taking cyclosporine alone. The authors theorize that rhubarb might reduce cyclosporine bioavailability by inducing of P-glycoprotein and/or cytochrome P450 3A4. However, since rhubarb was administered as a single oral dose and enzyme induction usually occurs after multiple doses, it is possible that cyclosporine absorption was actually reduced via rhubarb's stimulant laxative effects. Also, the composition of the rhubarb decoction was not described.
Digoxin (Lanoxin)
Theoretically, overuse of rhubarb might increase the risk of adverse effects when taken with digoxin.
Rhubarb has stimulant laxative effects. Overuse of rhubarb might cause potassium depletion, increasing the risk of digoxin toxicity.
Diuretic Drugs
Theoretically, frequent and high doses of rhubarb might increase the risk of hypokalemia.
Rhubarb has stimulant laxative effects. Overuse of rhubarb might cause potassium depletion and compound diuretic-induced potassium loss.
Hepatotoxic Drugs
Theoretically, concomitant use of rhubarb with potentially hepatotoxic drugs might increase the risk of developing liver damage.
Some animal research suggests that anthraquinones in rhubarb might have hepatotoxic effects. Also, rhubarb use has been linked to at least 24 cases of liver injury, although details on the dose of rhubarb and duration of use in these cases is unclear.
Nephrotoxic Drugs
Theoretically, long-term use of anthraquinones from rhubarb might increase the risk of nephrotoxicity when used with nephrotoxic drugs.
The anthraquinone constituents of rhubarb have been shown to induce nephrotoxicity in animal research. Additionally, in a case report, a 23-year old female presented with kidney failure after taking 6 tablets of a proprietary slimming agent (found to contain the anthraquinones emodin and aloe-emodin from rhubarb) daily for 6 weeks and then adding diclofenac 25 mg 4 times daily for 2 days. The authors postulate that the anthraquinone constituents of rhubarb contributed to the renal dysfunction, and the addition of diclofenac, a nephrotoxic drug, led to renal failure. Until more is known, advise patients to avoid taking rhubarb if they are taking other potentially nephrotoxic drugs.
Stimulant Laxatives
Theoretically, rhubarb might increase the risk for fluid and electrolyte loss when taken with other stimulant laxatives.
Rhubarb has stimulant laxative effects. Concomitant use with stimulant laxatives might compound fluid and electrolyte loss.
Warfarin (Coumadin)
Theoretically, excessive use of rhubarb might increase the risk of bleeding when taken with warfarin.
Rhubarb has stimulant laxative effects and can cause diarrhea. Diarrhea can increase the effects of warfarin, increase international normalized ratio (INR), and increase the risk of bleeding. Advise patients who take warfarin not to take excessive amounts of rhubarb.
Sheep Sorrel Plant Extract
Anticoagulant/Antiplatelet Drugs
Theoretically, sorrel might cause additive effects and side effects when used with anticoagulant or antiplatelet drugs.
In vitro, sorrel has been shown to inhibit platelet aggregation. However, this effect has not been reported in humans.
Fexofenadine (Allegra)
Sorrel might reduce the effectiveness of fexofenadine by reducing its absorption from the gut.
In vitro research shows that an ethanol extract of sorrel inhibits organic anion-transporting polypeptide 1A2 (OATP1A2), which transports fexofenadine from the intestine into cells. In rats, concomitant administration of sorrel extract with fexofenadine reduces oral absorption of fexofenadine and the area under the plasma concentration-time curve (AUC).
Organic Anion-Transporting Polypeptide Substrates (Oatp)
Sorrel might reduce the effectiveness of OATP substrates by reducing their absorption from the gut.
In vitro research shows that sorrel inhibits OATP1A2. Theoretically it may inhibit other OATPs. The OATPs are expressed in the small intestine and liver and transport drugs into cells. Inhibition of OATP may reduce the bioavailability of oral drugs that are substrates of OATP.
Burdock root extract
Anticoagulant/Antiplatelet Drugs
Theoretically, taking burdock with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
In vitro research shows that lignans from burdock reduce rabbit platelet aggregation by inhibiting platelet activating factor. This interaction has not been reported in humans.
Brand information
Manufacturer and brand details for Essiactive Tea Capsules, from the product label.
Zazzee Naturals
See all Zazzee Naturals products- Name
- Zazzee Naturals
- Street Address
- 400 Rella Boulevard Suite 123 Dept. 182
- City
- Montebello
- State
- NY
- ZipCode
- 10901
Essiactive Tea Capsules by Zazzee Naturals: Common Questions
Does Essiactive Tea Capsules by Zazzee Naturals interact with any medications?
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Does turkey rhubarb root in this product work as a laxative?
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Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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The Full Monographs Behind Essiactive Tea Capsules’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Burdock
Interacts with 122 drugsBurdock is a traditional herb most often used for skin problems and as a so-called 'blood purifier,' but high-quality human studies are lacking and most claims are not well proven. It is wid...
Read the full Burdock monograph → Herb & supplement monographSlippery Elm
Interacts with 2,022 drugsSlippery elm is a traditional herbal remedy made from the inner bark of a North American elm tree, used mainly to soothe sore throats and irritated digestive tracts. Its mucilage can coat an...
Read the full Slippery Elm monograph → Herb & supplement monographSorrel
Interacts with 169 drugsSorrel is a tangy, leafy herb used in cooking and traditional medicine, often for congestion, digestion, and inflammation. Solid human evidence for any health benefit is limited, and its hig...
Read the full Sorrel monograph → Herb & supplement monographRhubarb
Interacts with 658 drugsRhubarb root has a long history of use as a laxative and in traditional Chinese medicine, and its edible stalks are a common food. Most medicinal claims are backed by limited or low-quality...
Read the full Rhubarb monograph →Sources & How We Checked
Essiactive Tea Capsules's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 42 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Burdock 11 references
- Iwakami S, Wu JB, Ebizuka Y, Sankawa U. Platelet activating factor (PAF) antagonists contained in medicinal plants: lignans and sesquiterpenes. Chem Pharm Bull (Tokyo) 1992;40:1196-8. PubMed
- Sasaki Y, Kimura Y, Tsunoda T, Tagami H. Anaphylaxis due to burdock. Int J Dermatol 2003;42:472-3. PubMed
- Rhoads PM, Tong TG, Banner W Jr, Anderson R. Anticholinergic poisonings associated with commercial burdock root tea. J Toxicol Clin Toxicol 1984-85;22:581-4. PubMed
- Rodriguez P, Blanco J, Juste S, et al. Allergic contact dermatitis due to burdock (Arctium lappa). Contact Dermatitis 1995;33:134-5.
- Kassler, W. J., Blanc, P., and Greenblatt, R. The use of medicinal herbs by human immunodeficiency virus-infected patients. Arch Intern Med 1991;151(11):2281-2288. DOI
- Chan, Y. S., Cheng, L. N., Wu, J. H., Chan, E., Kwan, Y. W., Lee, S. M., Leung, G. P., Yu, P. H., and Chan, S. W. A review of the pharmacological effects of Arctium lappa (burdock). Inflammopharmacology. 2011;19(5):245-254. PubMed
- Breed, F. B. and Kuwabara, T. Burdock ophthalmia. Arch Ophthalmol 1966;75(1):16-20.
- Bryson, P. D., Watanabe, A. S., Rumack, B. H., and Murphy, R. C. Burdock root tea poisoning. Case report involving a commercial preparation. JAMA 5-19-1978;239(20):2157. DOI
- <p>Fletcher GF<span>, </span>Cantwell JD. Burdock root tea poisoning. JAMA <span>1978 Oct 6;240(15):1586.</span></p> DOI
- Latif A, Fichadiya H, Abid F, Capo G. Herbal Teas and Thrombocytopenia: A Curious Case of Yellow Dock and Burdock-Induced Thrombocytopenia. Eur J Case Rep Intern Med 2022;9(3):003247. PubMed
- Niazi B, Ahmed K, Ahmed M, Ali S, Song K, Elias S. Drug-Induced Liver Injury from Herbal Liver Detoxification Tea. Case Rep Gastroenterol 2022;16(3):612-617. PubMed
Slippery Elm 3 references
- The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
- Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
- Czarnecki D, Nixon R, Bekhor P, and et al. Delayed prolonged contact urticaria from the elm tree. Contact Dermatitis 1993;28:196-197. PubMed
Sorrel 8 references
- Neubauer N, Marz RW. Placebo-controlled, randomized, double-blind, clincal trial with Sinupret sugar coated tablets on the basis of a therapy with antibiotics and decongestant nasal drops in acute sinusitis. Phytomedicine 1994;1:177-81.
- Marz RW, Ismail C, Popp MA. Action profile and efficacy of a herbal combination preparation for the treatment of sinusitis. Wien Med Wochenschr 1999;149:202-8.
- Zick, S. M., Sen, A., Feng, Y., Green, J., Olatunde, S., and Boon, H. Trial of Essiac to ascertain its effect in women with breast cancer (TEA-BC). J Altern Complement Med 2006;12(10):971-980. PubMed
- Sanz, P. and Reig, R. Clinical and pathological findings in fatal plant oxalosis. A review. Am J Forensic Med Pathol. 1992;13(4):342-345. PubMed
- Gniazdowska, B., Doroszewska, G., and Doroszewski, W. [Hypersensitivity to weed pollen allergens in the region of Bygdoszcz]. Pneumonol.Alergol.Pol. 1993;61(7-8):367-372.
- Selçuk SN, Gülhan B, Düzova A, Teksam Ö. Acute tubulointerstitial nephritis due to large amount of sorrel (Rumex acetosa) intake. Clin Toxicol (Phila) 2015;53(5):497. PubMed
- Ahn JH, Kim J, Rehman NU, Kim HJ, Ahn MJ, Chung HJ. Effect of Rumex Acetosa Extract, a Herbal Drug, on the Absorption of Fexofenadine. Pharmaceutics. 2020;12(6):E547. PubMed
- Jeong D, Irfan M, Lee DH, Hong SB, Oh JW, Rhee MH. Rumex acetosa modulates platelet function and inhibits thrombus formation in rats. BMC Complement Med Ther. 2020;20(1):98. PubMed
Rhubarb 20 references
- Blumenthal M, ed. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Trans. S. Klein. Boston, MA: American Botanical Council, 1998.
- McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
- Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
- Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
- Nusko G, Schneider B, Schneider I, et al. Anthranoid laxative use is not a risk factor for colorectal neoplasia: results of a prospective case control study. Gut 2000;46:651-5. PubMed
- Kwan TH, Tong MK, Leung KT, et al. Acute renal failure associated with prolonged intake of slimming pills containing anthraquinones. Hong Kong Med J 2006;12:394-7.
- Fairbairn JW. The anthraquinone laxatives. Biological assay and its relation to chemical structure. Pharmacology 1976;14:48-61. PubMed
- Siegers, C. P., Hertzberg-Lottin, E., Otte, M., and Schneider, B. Anthranoid laxative abuse--a risk for colorectal cancer? Gut 1993;34(8):1099-1101. PubMed
- Fan, J. G. Evaluating the efficacy and safety of Danning Pian in the short-term treatment of patients with non-alcoholic fatty liver disease: a multicenter clinical trial. Hepatobiliary.Pancreat.Dis.Int 2004;3(3):375-380.
- Yan, M., Zhang, L. Y., Sun, L. X., Jiang, Z. Z., and Xiao, X. H. Nephrotoxicity study of total rhubarb anthraquinones on Sprague Dawley rats using DNA microarrays. J Ethnopharmacol. 4-15-2006; PubMed
- Zhang, J. H., Li, L. S., and Zhang, M. Clinical effects of rheum and captopril on preventing progression of chronic renal failure. Chin Med J (Engl.) 1990;103(10):788-793.
- Mitsuma, T., Yokozawa, T., Oura, H., and Terasawa, K. [Rhubarb therapy in patients with chronic renal failure (Part 2)]. Nippon Jinzo Gakkai Shi 1987;29(2):195-207.
- Wu, C. X. [A preliminary study on the effect of a single Rheum officinale in heavy doses in the treatment of acute icteric hepatitis]. Zhong.Xi.Yi.Jie.He.Za Zhi.(Chinese Journal of Modern Developments in Traditional Medicine) 1984;4(2):88-89.
- Jiao, D. H. [Clinical research on the hemostatic effect of rhubarb on peptic ulcer with acute bleeding]. Zhong.Xi.Yi.Jie.He.Za Zhi.(Chinese Journal of Modern Developments in Traditional Medicine) 1984;4(10):597-600, 579.
- Jiao, D. H., Ma, Y. H., Chen, S. J., Liu, C. T., Shu, H. N., and Chu, C. M. Resume of 400 cases of acute upper digestive tract bleeding treated by rhubarb alone. Pharmacology 1980;20 Suppl 1:128-130.
- Zhang, JH, Yao, XD, Song, Y, and et al. [Long-term treating effects of rhubarb and captopril in delaying the progression of renal failure]. Chinese Kidney Disease Journal 1993;9(4):197-201.
- Rehman H, Begum W, Anjum F, Tabasum H, Zahid S. Effect of rhubarb (Rheum emodi) in primary dysmenorrhoea: a single-blind randomized controlled trial. J Complement Integr Med. 2015 Mar;12(1):61-9.
- Yu CP, Lin HJ, Lin SP, Shia CS, Chang PH, Hou YC, Hsieh YW. Rhubarb decreased the systemic exposure of cyclosporine, a probe substrate of P-glycoprotein and CYP 3A. Xenobiotica. 2016 Aug;46(8):677-82. PubMed
- Byeon JH, Kil JH, Ahn YC, Son CG. Systematic review of published data on herb induced liver injury. J Ethnopharmacol 2019;233:190-6. PubMed
- Zhao D, Feng SX, Zhang HJ, et al. Pharmacokinetics, tissue distribution and excretion of five rhubarb anthraquinones in rats after oral administration of effective fraction of anthraquinones from rheum officinale. Xenobiotica. 2021;51(8):916-925. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC