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Dietary supplement

Extreme Potency Horny Goat Weed Extract Ingredients & Drug Interactions

by Herbadiet

Extreme Potency Horny Goat Weed Extract label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Extreme Potency Horny Goat Weed Extract against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Extreme Potency Horny Goat Weed Extract is a dietary supplement by Herbadiet with 1 active ingredient. Its ingredients are commonly taken for erectile dysfunction, low libido, fatigue and low energy.Based on those ingredients, 963 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Horny Goat Weed Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Extreme Potency Horny Goat Weed Extract by Herbadiet

Ask about any prescription or over-the-counter medication and we check it for interactions with Extreme Potency Horny Goat Weed Extract by Herbadiet — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Extreme Potency Horny Goat Weed Extract by Herbadiet

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: horny goat weed extract. The capsule itself is made from vegetable cellulose, an inert plant-based shell.

There are no other active ingredients.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Horny Goat Weed's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: Boosts libido and supports blood flow.
  • We looked for evidence on: Erectile dysfunction (ED), Sexual dysfunction, Fatigue, Sexual performance, Vascular function.
  • The closest evidence on file: Horny Goat Weed is rated "Insufficient Reliable Evidence To Rate" for Sexual dysfunction (Natural Medicines).
  • Also on file: Horny Goat Weed is rated "Insufficient Reliable Evidence To Rate" for Erectile dysfunction (ED), Fatigue.

The evidence we hold doesn't establish that horny goat weed works reliably for any condition. The data rates effectiveness as insufficient for sexual dysfunction, osteoporosis, bronchitis, and coronary heart disease.

That means studies so far haven't been robust enough to prove it helps—not that it definitely doesn't, just that we don't have solid proof yet.

The evidence, ingredient by ingredient Horny Goat Weed

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Short-term use of horny goat weed is generally well tolerated in most people. Common side effects include dizziness, dry mouth, nosebleed, thirst, and vomiting.

Long-term use has been linked to reports of vomiting, dry mouth, thirst, and nosebleed. Rarely, a case of rapid heartbeat (tachyarrhythmia) was reported in one person after two weeks of use, though it's unclear whether horny goat weed alone was responsible.

Because human safety data is limited and product quality varies widely between brands, caution is warranted. Pregnancy and breastfeeding safety data are insufficient to know either way.

The safety notes advise against use during pregnancy and while nursing. If you're pregnant, planning to become pregnant, or breastfeeding, talk with your doctor or pharmacist before taking this product.

Side effects, ingredient by ingredient Horny Goat Weed

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Horny Goat Weed.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 964 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take this product, double-check it against any blood thinners or antiplatelet drugs (Moderate severity), blood pressure medications (Moderate), estrogen-based therapies including birth control (Moderate), and any medications broken down by the liver enzymes CYP1A2, CYP2B6, or CYP3A4 (all Moderate). Use the interaction checker below to verify your exact medications.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

Horny goat weed extract has limited proven benefits and carries Moderate interaction risks with blood thinners, blood pressure medications, hormone therapies, and drugs metabolized by three major liver enzymes. If you take any prescription medication—especially anticoagulants, antiplatelets, or anything for heart or hormone health—check this product against your medication list first.

Consider talking with your pharmacist before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Nov 19, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Extreme Potency Horny Goat Weed Extract, straight from the product label.

Brand Herbadiet
Barcode (UPC) 880792447036
Net contents 60 V-Cap(s)
Market status On market
Date entered into DSLD Nov 19, 2021
DSLD ID 257554
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Extreme Potency Horny Goat Weed Extract by Herbadiet, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
60
UPC/BARCODE
880792447036
IngredientAmount% DV
Horny Goat Weed Extract100 mg--

Other ingredients: Vegetable Cellulose Shell

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Herbadiet Horny Goat Weed is a high potency 98% standardized extract. This full spectrum extract retains all the active constituents in nature intended balanced ratio. Encapsulating this goodness in our quick release, easy to swallow vegan capsules, guarantees you a premum quality nutritional supplement.

Formulation

Boosts libido Supports blood flow Sexual wellness

Natural color variation may occur in this product

100% natural Sexual wellness

Non-GMO

Suitable for vegetarians and vegans

Free Of preservatives, binders, gluten, artificial ingredients, dairy, soy, wheat, yeast

Every batch 3rd party lab tested

FDA Disclaimer Statement

These statements have not been evaluated by FDA. This product is not intended to diagnose, treat, cure or prevent any disease.

Precautions

Do not use if seal under the cap is broken or missing. Dietary supplement shouldn't be used as a substitute for a varied diet

Caution: If you are pregnant, breast feeding, or taking medications, consult your doctor before use.

Discontinue use and consult your doctor if any adverse reactions occur.

Keep out of reach of children.

Not for medicinal use

Storage

Store in cool, dry place

Seals/Symbols

fssai Lic. No.: 20817018000147 Vcaps Plus GMP Good Manufacturing Practice Quality Product

General Statements

1% for the planet

License Number: 10018064001315

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Directions for Use: Take 1 capsule twice a day, preferably with meals with a full glass of water or as directed by your physician.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Extreme Potency Horny Goat Weed Extract by Herbadiet label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Extreme Potency Horny Goat Weed Extract label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Extreme Potency Horny Goat Weed Extract by Herbadiet

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

Horny Goat Weed Extract

Interacts with
963 drugs
100 mg per serving Form: Icariin

Horny goat weed (Epimedium) is a traditional Chinese herb most often marketed for low libido and erectile problems, but solid human evidence for these...

Horny Goat Weed Extract monograph & interactions

Other (inactive) ingredients: Vegetable Cellulose Shell. These complete the product’s ingredient list but are not active constituents.

Interaction report

Extreme Potency Horny Goat Weed Extract by Herbadiet Drug Interactions

Want to check YOUR meds against Extreme Potency Horny Goat Weed Extract?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
963Drugs
963 Moderate

Ingredients driving the most interactions

Horny Goat Weed Extract 963

Individual Drug Interactions

The ingredients in Extreme Potency Horny Goat Weed Extract interact with 963 drugs. Click any drug to see the details.

1 of the 1 ingredient in Extreme Potency Horny Goat Weed Extract interact with drugs. Each result below shows which ingredient is responsible. Horny Goat Weed Extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Extreme Potency Horny Goat Weed Extract with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Horny Goat Weed Extract6 drug types · 963 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, horny goat weed might increase the risk of bleeding.
In vitro research and animal research shows that horny goat weed can inhibit platelet aggregation and thrombus formation. This effect has not been reported in humans.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, horny goat weed might increase the risk of hypotension.
Laboratory research suggests that horny goat weed might have hypotensive effects. This effect has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, horny goat weed might increase the effects and side effects of CYP1A2 substrates.
In vitro, horny goat weed leaf extract inhibits CYP1A2. This effect has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2B6 (Cyp2B6) Substrates

Theoretically, horny goat weed might increase the effects and side effects of CYP2B6 substrates.
In vitro, horny goat weed leaf extract inhibits CYP2B6. This effect has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, horny goat weed might increase the effects and side effects of CYP3A4 substrates.
In vitro, horny goat weed extract inhibits CYP3A4 and suppresses CYP3A4 mRNA expression. This effect has not been reported in humans.

Likelihood Possible Evidence D
Estrogens

Theoretically, concomitant use of horny goat weed with estrogens might increase their therapeutic and adverse effects.
In vitro evidence suggests that horny goat weed has estrogenic activity. In clinical research, horny goat weed has been shown to increase blood levels of estrogen in some females.

Likelihood Possible Evidence D
Horny Goat Weed Extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Extreme Potency Horny Goat Weed Extract, from the product label.

Herbadiet

See all Herbadiet products
Name
Arkure Health Care
City
Haryana
State
India
Web Address
www.herbadiet.in
Pharmacist Counseling Corner

Extreme Potency Horny Goat Weed Extract by Herbadiet: Common Questions

Does Extreme Potency Horny Goat Weed Extract by Herbadiet interact with any medications?
Yes. Based on its ingredients, Extreme Potency Horny Goat Weed Extract has a known interaction with 963 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Extreme Potency Horny Goat Weed Extract contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm on a blood thinner?
You should check with your pharmacist first. Horny goat weed may theoretically increase bleeding risk based on lab research, and this is rated a Moderate concern. Don't start it without confirming it's safe for your specific medication.
What are the most common side effects?
Dizziness, dry mouth, nosebleed, thirst, and vomiting. These are the ones reported most often with short-term use. Long-term use carries similar risks.
Is this safe to take long-term?
The data we have is strongest for short-term use, where it's generally well tolerated. Long-term safety hasn't been well studied. If you're considering using it regularly, ask your pharmacist.
Can I take this if I'm on birth control?
You should check with your pharmacist. Horny goat weed has estrogenic activity and may increase estrogen levels, which could theoretically change how birth control works or raise your side effects. It's a Moderate-severity concern.
Does quality vary between different brands?
Yes. The safety notes flag that quality varies between products, so you may not get the same strength or purity from one brand to another. This is one reason to choose from established, reputable makers.
Is this effective for sexual dysfunction?
The evidence we hold doesn't establish that it reliably works. Studies so far haven't been strong enough to prove benefit for sexual dysfunction or other claimed uses.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Extreme Potency Horny Goat Weed Extract is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Extreme Potency Horny Goat Weed Extract label
Go deeper

The Full Monographs Behind Extreme Potency Horny Goat Weed Extract’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Horny Goat Weed

Interacts with 963 drugs

Horny goat weed (Epimedium) is a traditional Chinese herb most often marketed for low libido and erectile problems, but solid human evidence for these uses is lacking. While short-term use s...

Read the full Horny Goat Weed monograph →
Sources

Sources & How We Checked

Extreme Potency Horny Goat Weed Extract's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 11 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Horny Goat Weed 11 references
  1. Cirigliano MD, Szapary PO. Horny goat weed for erectile dysfunction. Alt Med Alert 2001;4:19-22.
  2. Partin JF, Pushkin YR. Tachyarrhythmia and hypomania with horny goat weed. Psychosomatics 2004;45:536-7. PubMed
  3. De Naeyer A, Pocock V, Milligan S, De Keukeleire D. Estrogenic activity of a polyphenolic extract of the leaves of Epimedium brevicornum. Fitoterapia 2005;76:35-40. PubMed
  4. Zhang CZ, Wang SX, Zhang Y, et al. In vitro estrogenic activities of Chinese medicinal plants traditionally used for the management of menopausal symptoms. J Ethnopharmacol 2005;98:295-300. PubMed
  5. Yap SP, Shen P, Li J, et al. Molecular and pharmacodynamic properties of estrogenic extracts from the traditional Chinese medicinal herb, Epimedium. J Ethnopharmacol 2007;113:218-24. PubMed
  6. Yan, F. F., Liu, Y., Liu, Y. F., and Zhao, Y. X. Herba Epimedii water extract elevates estrogen level and improves lipid metabolism in postmenopausal women. Phytother.Res. 2008;22(9):1224-1228. PubMed
  7. Ramanathan VS, Mitropoulos E, Shlopov B, et al. An Enzyte'ing' case of acute hepatitis. J Clin Gastroenterol 2011;45(9):834-5. PubMed
  8. Zhong Q, Shi Z, Zhang L, et al. The potential of Epimedium koreanum Nakai for herb-drug interaction. J Pharm Pharmacol 2017;69(10):1398-408. doi: 10.1111/jphp.12773.
  9. Irfan M, Kwon TH, Lee DH, et al. Antiplatelet and Antithrombotic Effects of Epimedium koreanum Nakai. Evid Based Complement Alternat Med. Apr 2021;2021:7071987. PubMed
  10. Tan K, Yang W, Pang L, Hou F. Differences in clinical characteristics among 726 patients with Chinese herbal medicine- or Western medicine-induced liver injury. Medicine (Baltimore) 2022;101(32):e29909. PubMed
  11. Li K, Yu XH, Maskey AR, et al. Cytochrome P450 3A4 suppression by epimedium and active compound kaempferol leads to synergistic anti-inflammatory effect with corticosteroid. Front Pharmacol 2023;13:1042756. PubMed

See these in context on the Horny Goat Weed monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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