Interactions on record — worth a quick check against your medications. Check your meds →
Dietary supplement

Passion Ingredients & Drug Interactions

by Her Own

Passion label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Passion against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Passion is a dietary supplement by Her Own with 6 active ingredients. Its ingredients are commonly taken for enlarged prostate (bph) symptoms, seasonal allergies, joint pain and arthritis.Based on those ingredients, 1,155 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Horny Goat Weed Leaf, Stem Extract, Hops Strobile Extract, Fenugreek Seed Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Passion by Her Own

Ask about any prescription or over-the-counter medication and we check it for interactions with Passion by Her Own — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Passion by Her Own

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 3, 2026

What’s inside

Partial disclosure
Ingredient Transparency · database check
Partial

Most active ingredients list an amount, but at least one is hidden in a blend or missing.

Why this rating?
  • The label discloses an exact amount for 3 of its 6 active ingredients.
  • “Proprietary Blend” is a proprietary blend — the label gives one combined amount (200 mg) without saying how much of each component you get.

Passion contains six active ingredients in a proprietary blend: nettle root extract, maca powder, oat straw extract, hops strobile extract, fenugreek seed extract, and horny goat weed leaf and stem extract. The blend is packaged in a capsule with inactive ingredients—hypromellose, microcrystalline cellulose, silica, and magnesium stearate—which serve as the capsule material and binding agents.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: Libido, mood, energy, and sexual desire.
  • We looked for evidence on: Erectile dysfunction (ED), Antidepressant-induced sexual dysfunction, Depression, Anxiety, Fatigue, Age-related testosterone deficiency — and 4 related terms.
  • The strongest evidence on file: Fenugreek is rated "Possibly Effective" for Sexual dysfunction (Natural Medicines).
  • Also on file: Maca is rated "Insufficient Reliable Evidence To Rate" for Antidepressant-induced sexual dysfunction, Chronic fatigue syndrome (CFS), Depression, Fatigue, and more.
  • Also on file: Horny Goat Weed is rated "Insufficient Reliable Evidence To Rate" for Sexual dysfunction.

The evidence for Passion's individual ingredients is mixed. Oat straw extract is rated likely effective for lowering cholesterol and supporting heart health.

Nettle root is possibly effective for diabetes management, though evidence for hay fever, anemia, asthma, enlarged prostate, and gum disease remains insufficient. Fenugreek seed is possibly effective for sexual function and period pain as well as blood sugar control.

For horny goat weed, sexual dysfunction, bronchitis, bone health, and heart disease all lack sufficient reliable evidence to rate. Maca powder similarly shows insufficient evidence for amenorrhea, chronic disease anemia, sexual dysfunction related to antidepressants, athletic performance, and osteoporosis.

Hops extract has insufficient evidence for cognitive decline, sexual function, anxiety, ADHD, indigestion, and sleep. The product's overall benefit depends on which of these supported uses matches your goals.

The evidence, ingredient by ingredient Stinging Nettle Oats Hops Maca Fenugreek Horny Goat Weed

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 6 of the 6 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 6 of 6.
  • General safety write-ups exist for 6 of 6.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Nettle root is generally well tolerated but may cause constipation or diarrhea. Rare cases of liver injury have been reported with herbal products containing nettle, and one case report links a patient's unusual tongue swelling to raw nettle leaf.

Oat straw extract is well tolerated with common side effects limited to bloating, gas, and abdominal distention from its fiber content—these usually ease with continued use. Hops strobile extract is generally tolerated short-term but may cause drowsiness; long-term safety is not well studied.

Fenugreek seed commonly causes stomach pain, bloating, diarrhea, and nausea; rare severe allergic reactions including throat swelling and difficulty breathing have been reported. Horny goat weed seems well tolerated short-term, with dizziness, dry mouth, nosebleeds, and thirst reported; one case of irregular heart rhythm was recorded after two weeks of use.

Regarding pregnancy: nettle root is likely unsafe, fenugreek seed is likely unsafe, horny goat weed is possibly unsafe, and hops extract is not recommended. Maca and oat straw extract lack sufficient safety data in pregnancy—discuss with your doctor before use.

For breastfeeding: nettle root and hops extract should be avoided; fenugreek seed is possibly safe (often used to boost milk supply, but evidence is limited); maca, oat straw extract, and horny goat weed lack adequate safety data—talk with your healthcare provider before taking any while nursing.

Side effects, ingredient by ingredient Stinging Nettle Oats Hops Maca Fenugreek Horny Goat Weed

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 5 of the 6 matched ingredients can interact with medications — Stinging Nettle, Horny Goat Weed, Fenugreek, Oats, Hops.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications; lithium.
  • For scale: 1,156 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking Passion, check with your doctor or pharmacist if you take blood thinners (warfarin, clopidogrel, or other anticoagulants or antiplatelets)—nettle root, fenugreek seed, and horny goat weed all carry a Moderate risk of increased bleeding. If you take diabetes medications or insulin, all three blood-sugar-affecting ingredients (nettle root, oat straw extract, fenugreek seed) may lower your blood sugar further.

Medications metabolized through your liver (including certain antidepressants, heart medications, and other drugs broken down by CYP1A2, CYP2B6, or CYP3A4 enzymes) may be affected by horny goat weed and hops extract. Lithium, estrogen therapies, theophylline, blood pressure drugs, seizure medications, and sedating drugs all have documented Moderate interactions with one or more ingredients.

No interactions are documented for maca powder among the ingredients we could check, but confirm all your medications with your own healthcare provider before starting.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glancePartially disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Passion may appeal to people interested in supporting sexual function and general wellness based on its traditional herbal ingredients, but several of those ingredients—especially nettle root and fenugreek seed—have important interactions with common medications like blood thinners, diabetes drugs, and lithium. If you're taking any prescription medication, especially for blood clotting, blood sugar, mood, or blood pressure, check your specific drugs against this product's ingredient list before starting.

Women who are pregnant or breastfeeding should talk with their doctor before use. Have a conversation with your own pharmacist or doctor to see if Passion fits your health situation and current medications.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 6 of 6 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Apr 23, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Passion, straight from the product label.

Brand Her Own
Barcode (UPC) 035046128982
Net contents 30 Capsule(s)
Market status On market
Date entered into DSLD Apr 23, 2024
DSLD ID 307911
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult Female (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Passion by Her Own, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
30
UPC/BARCODE
035046128982
IngredientAmount% DV
Proprietary Blend200 mg--
Nettle root extract0 NP--
Maca, Powder150 mg--
Oat Straw Extract0 NP--
Hops Strobile Extract0 NP--
Fenugreek Seed Extract150 mg--
Horny Goat Weed Leaf, Stem Extract150 mg--

Other ingredients: Hypromellose, Microcrystalline Cellulose, Silica, Magnesium Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

In the mood Passion supports: Libido Mood Energy Desire

Vegan

Non GMO Gluten free Soy free No synthetic colors or preservatives

Made in USA from globally sourced ingredients

Excite & ignite Light that fire with the ultimate sexual health formula

General Statements

We create essential health supplements formulated for the modern woman's everyday needs. Her Own is women's wellness, evolved.

Facebook Instagram @herownnutrition Please recycle

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Formula

Horny goat weed Boosts sex drive Maca root Supports mood & energy Fenugreek Increases sexual desire

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Directions: Take 1 capsule up to 2 times daily as a dietary supplement or as directed by a healthcare professional.

Precautions

Keep out of reach of children.

Do not use if seal is broken.

Storage

Store in a cool, dry place. Protect from heat, light and moisture.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Passion by Her Own label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Passion label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Passion by Her Own

These are the 6 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Proprietary Blend

200 mg per serving

Maca, Powder

No known
interactions
150 mg per serving

Maca is a nutrient-rich Andean root often used for energy, libido, and menopause symptoms. Early studies suggest it may modestly help sexual desire an...

Maca, Powder monograph & interactions

Fenugreek Seed Extract

Interacts with
389 drugs
150 mg per serving

Fenugreek is a common kitchen spice that is also taken as a supplement, mainly for blood sugar, cholesterol, and to support breast milk production. So...

Fenugreek Seed Extract monograph & interactions

Horny Goat Weed Leaf, Stem Extract

Interacts with
963 drugs
150 mg per serving Form: Epimedium sagittatum Leaf Extract, Epimedium sagittatum Stem Extract, Icariins

Horny goat weed (Epimedium) is a traditional Chinese herb most often marketed for low libido and erectile problems, but solid human evidence for these...

Horny Goat Weed Leaf, Stem Extract monograph & interactions

Other (inactive) ingredients: Hypromellose, Microcrystalline Cellulose, Silica, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Passion by Her Own Drug Interactions

Want to check YOUR meds against Passion?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
1,155Drugs
1,155 Moderate

Ingredients driving the most interactions

Horny Goat Weed Leaf, Stem Extract 963
Hops Strobile Extract 863
Fenugreek Seed Extract 389
Nettle root extract 164
Oat Straw Extract 86

Individual Drug Interactions

The ingredients in Passion interact with 1,155 drugs. Click any drug to see the details.

5 of the 6 ingredients in Passion interact with drugs. Each result below shows which ingredient is responsible. Horny Goat Weed Leaf, Stem Extract Hops Strobile Extract Fenugreek Seed Extract Nettle root extract Oat Straw Extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Passion with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Horny Goat Weed Leaf, Stem Extract6 drug types · 963 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, horny goat weed might increase the risk of bleeding.
In vitro research and animal research shows that horny goat weed can inhibit platelet aggregation and thrombus formation. This effect has not been reported in humans.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, horny goat weed might increase the risk of hypotension.
Laboratory research suggests that horny goat weed might have hypotensive effects. This effect has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, horny goat weed might increase the effects and side effects of CYP1A2 substrates.
In vitro, horny goat weed leaf extract inhibits CYP1A2. This effect has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2B6 (Cyp2B6) Substrates

Theoretically, horny goat weed might increase the effects and side effects of CYP2B6 substrates.
In vitro, horny goat weed leaf extract inhibits CYP2B6. This effect has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, horny goat weed might increase the effects and side effects of CYP3A4 substrates.
In vitro, horny goat weed extract inhibits CYP3A4 and suppresses CYP3A4 mRNA expression. This effect has not been reported in humans.

Likelihood Possible Evidence D
Estrogens

Theoretically, concomitant use of horny goat weed with estrogens might increase their therapeutic and adverse effects.
In vitro evidence suggests that horny goat weed has estrogenic activity. In clinical research, horny goat weed has been shown to increase blood levels of estrogen in some females.

Likelihood Possible Evidence D
Horny Goat Weed Leaf, Stem Extract full monograph & interactions

Hops Strobile Extract4 drug types · 863 drugs

Cns Depressants

Theoretically, concomitant use of hops with sedative drugs might cause additive sedation.
Some animal research shows that hops has sedative effects.

Likelihood Possible Evidence D
Estrogens

Theoretically, concomitant use of large amounts of hops might interfere with hormone replacement therapy due to competition for estrogen receptors.
In vitro research suggests that certain hops constituents can competitively bind to estrogen receptors. However, most hops extracts contain very small amounts of these constituents.

Likelihood Possible Evidence D
Cytochrome P450 1A2 (Cyp1A2) Substrates

Hops extract does not seem to affect the metabolism of CYP1A2 substrates.
In vitro research suggests that flavonoid constituents of hops inhibit CYP1A2 enzyme activity. However, a pharmacokinetic study in healthy postmenopausal patients shows that taking a standardized extract of spent hops containing prenylated phenols, as 59.5 mg twice daily for 2 weeks, does not affect levels of caffeine, a CYP1A2 probe substrate.

Likelihood Unlikely Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, hops extract might alter metabolism of CYP3A4 substrates; however, this effect may not be clinically significant.
Animal research suggests that specific constituents of hops, called lupulones, can induce hepatic CYP3A4 enzyme activity. However, a pharmacokinetic study in healthy postmenopausal patients with normal metabolism shows that taking a standardized extract of spent hops containing prenylated phenols, as 59.5 mg twice daily for 2 weeks, decreases the concentration of alprazolam, a CYP3A4 probe substrate, by 7.6%. This reduction is unlikely to be clinically relevant.

Likelihood Possible Evidence D
Hops Strobile Extract full monograph & interactions

Fenugreek Seed Extract9 drug types · 389 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, fenugreek might have additive effects when used with anticoagulant or antiplatelet drugs.
Some of the constituents in fenugreek have antiplatelet effects in animal and in vitro research. However, common fenugreek products might not contain sufficient concentrations of these constituents for clinical effects. A clinical study in patients with coronary artery disease or diabetes shows that taking fenugreek seed powder 2.5 grams twice daily for 3 months does not affect platelet aggregation, fibrinolytic activity, or fibrinogen levels .

Likelihood Unlikely Evidence B
Antidiabetes Drugs

Theoretically, fenugreek seed might have additive hypoglycemic effects when used with antidiabetes drugs.
Clinical research shows that fenugreek seed can reduce fasting blood glucose and 2-hour postprandial glucose levels in adults with type 2 diabetes.

Likelihood Probable Evidence B
Clopidogrel (Plavix)

Theoretically, fenugreek seed might alter the clinical effects of clopidogrel by inhibiting its conversion to the active form.
Animal research shows that fenugreek seed 200 mg/kg daily for 14 days increases the maximum serum concentration of clopidogrel by 21%. It is unclear how this affects the pharmacokinetics of the active metabolite of clopidogrel; however, this study found that concomitant use of fenugreek seed and clopidogrel prolonged bleeding time by an additional 11%.

Likelihood Possible Evidence D
Metoprolol (Toprol)

Theoretically, fenugreek seed might have additive hypotensive effects when used with metoprolol.
Animal research shows that fenugreek seed 300 mg/kg daily for 2 weeks decreases systolic and diastolic blood pressure by 9% and 11%, respectively, when administered alone, and by 15% and 22%, respectively, when given with metoprolol 10 mg/kg.

Likelihood Probable Evidence B
Phenytoin (Dilantin)

Theoretically, fenugreek might decrease plasma levels of phenytoin.
Animal research shows that taking fenugreek seeds for 1 week decreases maximum concentrations and the area under the curve of a single dose of phenytoin by 44% and 72%, respectively. This seems to be related to increased clearance. So far, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Sildenafil (Viagra)

Theoretically, concurrent use of sildenafil and fenugreek might reduce levels and therapeutic effects of sildenafil.
Animal research shows that taking fenugreek seeds for 1 week reduces maximum concentrations and the area under the curve of a single dose of sildenafil by 27% and 48%, respectively. So far, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Theophylline

Theoretically, fenugreek may reduce the levels and clinical effects of theophylline.
Animal research shows that fenugreek 50 grams daily for 7 days reduces the maximum serum concentration (Cmax) of theophylline by 28% and the area under the plasma drug concentration-time curve (AUC) by 22%.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Theoretically, fenugreek might have additive effects with warfarin and increase the international normalized ratio (INR).
Some fenugreek constituents have antiplatelet effects, although these might not be present in concentrations that are clinically significant. In one case report, a patient taking warfarin experienced an increased INR when starting to take fenugreek in combination with boldo.

Likelihood Possible Evidence D
Antihypertensive Drugs

Fenugreek may also have an additive effect on blood pressure-lowering medications. Studies on animals have shown that fenugreek seed can decrease both systolic and diastolic blood pressure by up to 22% when combined with metoprolol. Therefore, it is essential to monitor your blood pressure regularly if you are taking fenugreek and metoprolol together or any other antihypertensive drugs.

Likelihood Possible Evidence C
Fenugreek Seed Extract full monograph & interactions

Nettle root extract4 drug types · 164 drugs

Antidiabetes Drugs

Theoretically, stinging nettle might have additive effects with antidiabetes drugs.
Clinical research shows that stinging nettle might decrease blood glucose levels in patients with diabetes.

Likelihood Possible Evidence B
Diuretic Drugs

Theoretically, combining stinging nettle with diuretic drugs may have additive effects.
Animal research suggests that the above ground parts and roots of stinging nettle may have a diuretic effect.

Likelihood Possible Evidence D
Lithium

Theoretically, stinging nettle might reduce excretion and increase levels of lithium.
Animal research suggests that stinging nettle has diuretic and natriuretic properties, which could alter the excretion of lithium. The dose of lithium might need to be decreased.

Likelihood Possible Evidence D
Warfarin (Coumadin)

There is some concern that stinging nettle might decrease the effects of anticoagulant drugs such as warfarin.
Stinging nettle contains a significant amount of vitamin K. When taken in large quantities, this might interfere with the activity of warfarin.

Likelihood Possible Evidence D
Nettle root extract full monograph & interactions

Oat Straw Extract2 drug types · 86 drugs

Antidiabetes Drugs

Theoretically, oats may have additive effects with antidiabetic agents and might increase the risk of hypoglycemia.
Consuming oats can decrease blood glucose in patients with diabetes. In those who require insulin, taking oats 100 grams daily for 2 days reduces the insulin dose required to achieve metabolic control.

Likelihood Possible Evidence D
Insulin

Concomitant use of oats and insulin might increase the risk of hypoglycemia.
In patients with insulin-dependent type 2 diabetes, taking oats 100 grams daily for 2 days reduces the insulin dose required to achieve metabolic control.

Likelihood Possible Evidence B
Oat Straw Extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Passion, from the product label.

Her Own

See all Her Own products
Name
Windmill Health Products
Street Address
10 Henderson Drive
City
West Caldwell
State
NJ
ZipCode
07006
Web Address
herown.com
Pharmacist Counseling Corner

Passion by Her Own: Common Questions

Does Passion by Her Own interact with any medications?
Yes. Based on its ingredients, Passion has a known interaction with 1,155 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Passion contains 6 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is it safe to take Passion if I'm pregnant?
No. Nettle root is likely unsafe during pregnancy, and fenugreek seed is likely unsafe as well. Horny goat weed is possibly unsafe. Even though maca and oat straw extract lack enough safety data to rate, the presence of ingredients with known pregnancy concerns makes this product not recommended. Talk with your doctor before considering any herbal supplement in pregnancy.
Can I take Passion while breastfeeding?
There isn't enough safety data to say it's safe. Nettle root and hops extract should be avoided while breastfeeding. Fenugreek seed is possibly safe—it's often used to support milk supply, but evidence is limited and you should discuss it with your healthcare provider first. Maca, oat straw extract, and horny goat weed lack adequate safety information, so talk with your doctor before starting.
What does each ingredient in Passion do?
Nettle root is possibly effective for diabetes management. Oat straw extract is likely effective for cholesterol and heart health. Fenugreek seed is possibly effective for sexual function, period pain, and blood sugar control. Maca, hops extract, and horny goat weed all have insufficient evidence to say they work for their traditional uses. The product is marketed for overall wellness, but most individual benefits remain unproven.
What are the most common side effects of Passion?
Nettle root may cause constipation or diarrhea. Oat straw extract commonly causes bloating, gas, and abdominal distention from its fiber content—these usually improve with continued use. Fenugreek seed often causes stomach pain, bloating, diarrhea, and nausea. Horny goat weed may cause dizziness, dry mouth, nosebleeds, and thirst. Hops can cause drowsiness.
Does oat straw extract really help cholesterol and heart health?
Yes, oat straw extract is rated likely effective for lowering cholesterol and supporting heart health based on the evidence we hold. However, the ingredient comes with a Moderate interaction risk with diabetes drugs and insulin, so if you take either, check with your doctor first.
Can fenugreek in this product affect my blood sugar?
Yes. Fenugreek seed can lower blood sugar, so if you take diabetes medications or insulin, combining them with this product may lower your blood sugar too much, increasing the risk of low blood sugar (hypoglycemia). Talk with your doctor or pharmacist before taking Passion if you manage diabetes with medication.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Passion label
Go deeper

The Full Monographs Behind Passion’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Stinging Nettle

Interacts with 164 drugs

Stinging nettle is a common plant used as food and in traditional medicine, most often for prostate symptoms, allergies, and joint pain. The evidence is mixed and mostly preliminary, so it i...

Read the full Stinging Nettle monograph → Herb & supplement monograph

Oats

Interacts with 86 drugs

Oats are a well-studied whole grain whose soluble fiber (beta-glucan) can help lower cholesterol and support heart health when eaten regularly. As a food, oats are safe for most people, and...

Read the full Oats monograph → Herb & supplement monograph

Hops

Interacts with 863 drugs

Hops are most often used for sleep and mild anxiety, frequently combined with valerian, but the human evidence is limited and not very strong. They are generally well tolerated when used sho...

Read the full Hops monograph → Herb & supplement monograph

Maca

Maca is a nutrient-rich Andean root often used for energy, libido, and menopause symptoms. Early studies suggest it may modestly help sexual desire and some menopause symptoms, but the evide...

Read the full Maca monograph → Herb & supplement monograph

Fenugreek

Interacts with 389 drugs

Fenugreek is a common kitchen spice that is also taken as a supplement, mainly for blood sugar, cholesterol, and to support breast milk production. Some early research is encouraging for blo...

Read the full Fenugreek monograph → Herb & supplement monograph

Horny Goat Weed

Interacts with 963 drugs

Horny goat weed (Epimedium) is a traditional Chinese herb most often marketed for low libido and erectile problems, but solid human evidence for these uses is lacking. While short-term use s...

Read the full Horny Goat Weed monograph →
Sources

Sources & How We Checked

Passion's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 93 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Stinging Nettle 23 references
  1. Monographs on the medicinal uses of plant drugs. Exeter, UK: European Scientific Co-op Phytother, 1997.
  2. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  3. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
  4. Schulz V, Hansel R, Tyler VE. Rational Phytotherapy: A Physician's Guide to Herbal Medicine. Terry C. Telger, transl. 3rd ed. Berlin, GER: Springer, 1998.
  5. Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
  6. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  7. Mittman P. Randomized, double-blind study of freeze-dried Urtica dioica in the treatment of allergic rhinitis. Planta Med 1990;56:44-7.
  8. Vontobel HP, Herzog R, Rutishauser G, Kres H. [Results of a double-blind study on the effectiveness of ERU (extractum radicis Urticae) capsules in conservative treatment of benign prostatic hyperplasia]. (Abstract). Urologe A 1985;24:49-51.
  9. Randall C, Randall H, Dobbs F, et al. Randomized controlled trial of nettle sting for treatment of base-of-thumb pain. J R Soc Med 2000;93:305-9. PubMed
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Maca 1 reference
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Oats 13 references
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Hops 15 references
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Fenugreek 30 references
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Horny Goat Weed 11 references
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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