Eyebright Ingredients & Drug Interactions
by Herb Pharm
What is this page for?
First and foremost: checking Eyebright against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Eyebright is a dietary supplement by Herb Pharm with 1 active ingredient. Its ingredients are commonly taken for eye irritation and redness, conjunctivitis (pink eye), eye strain.Based on those ingredients, 86 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Eyebright Flowering Aerial Parts Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Eyebright by Herb Pharm
Ask about any prescription or over-the-counter medication and we check it for interactions with Eyebright by Herb Pharm — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Eyebright by Herb Pharm
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: Eyebright Flowering Aerial Parts Extract, a liquid concentrate of the eyebright plant's above-ground flowering parts. The extract is suspended in water and cane alcohol as inactive ingredients.
Does it work?
Not established
The evidence for eyebright doesn't yet support a strong rating. The facts show insufficient reliable evidence for hay fever, the common cold, cough, sore throat, and sinus infections — all conditions this herb is traditionally used for.
That means studies either haven't been done, aren't robust enough, or show mixed results. We can't say it works for these purposes based on the data we hold.
How safe is it?
Well-documented data
When taken by mouth, eyebright is likely safe in small amounts as a tea, though some people have reported confusion, headache, nausea, constipation, cough, shortness of breath, and nasal congestion. Important: never put homemade or non-sterile eyebright directly in your eye — that carries real risk.
During pregnancy, safety has not been established, so it's best avoided. The same goes for breastfeeding — there isn't enough safety information, so avoid use while nursing.
Meds to double-check
Moderate interaction found
If you take any diabetes medication — insulin, metformin, or any other class — check your exact drugs with the search tool on this page before starting. Eyebright may lower blood sugar, and combined use could push your levels too low.
The bottom line
Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.
Eyebright is a traditional herbal remedy for respiratory and eye complaints, but the evidence backing those uses isn't solid yet. If you take diabetes medication, talk to your pharmacist before starting this product — there's a moderate risk of low blood sugar.
And whether or not you're on medications, steer clear of putting it directly in your eye unless you're under professional guidance.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jul 24, 2025.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Eyebright, straight from the product label.
| Brand | Herb Pharm |
|---|---|
| Barcode (UPC) | 090700001490 |
| Net contents | 4 Fluid Ounce(s); 120 mL |
| Market status | On market |
| Date entered into DSLD | Jul 24, 2025 |
| DSLD ID | 334523 |
| Product type | Botanical |
| Supplement form | Liquid |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Organic, Gluten Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Eyebright by Herb Pharm, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Eyebright Flowering Aerial Parts Extract | 682 mg | -- |
Other ingredients: Water, Distilled, Cane Alcohol
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Suggested use Shake well before using Adults: Add 1 squeeze of the dropper bulb to 2 oz. of water or juice, 2 to 5 times per day. Best taken between meals.
Precautions
Keep out of the reach of children
Storage
Store away from heat & light
Formula
Euphrasia spp.
Eyebright liquid extract
Formulation
Respiratory system
USDA Organic
Gluten-free
Certified organic by Organic Certifiers
Seals/Symbols
USDA Organic
FDA Disclaimer Statement
This statement has not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Eyebright by Herb Pharm label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Eyebright by Herb Pharm
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size0.7 mL Dosage formLiquid Servings per container168 Amounts shown are per serving.
Eyebright Flowering Aerial Parts Extract
Interacts with86 drugs
Eyebright is a traditional herb long used for minor eye irritation, redness, and allergy symptoms, but high-quality human studies are very limited. Th...
Eyebright Flowering Aerial Parts Extract monograph & interactionsOther (inactive) ingredients: Water, Distilled, Cane Alcohol. These complete the product’s ingredient list but are not active constituents.
Eyebright by Herb Pharm Drug Interactions
HelloPharmacist Interaction Report
Herb Pharm's Eyebright is a single-ingredient liquid extract that does interact with one class of medications.
The main concern is with diabetes drugs (antidiabetes medications). Animal research suggests eyebright may lower blood sugar levels, so when combined with diabetes medications, there's a theoretical risk of blood sugar dropping too low (hypoglycemia).
This is rated a Moderate interaction.
Read the full breakdown — every affected drug type, severity by severity
If you take any medication to manage blood sugar — whether insulin, metformin, sulfonylureas, or another class — you'll want to check your exact drugs with the tool below before starting this product. Altogether, these interactions span 85 individual medications.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Eyebright?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Eyebright interact with 86 drugs. Click any drug to see the details.
1 of the 1 ingredient in Eyebright interact with drugs. Each result below shows which ingredient is responsible. Eyebright Flowering Aerial Parts Extract
AcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Eyebright — through 1 ingredient. Tap an ingredient for the detail:
Eyebright Flowering Aerial Parts ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, eyebright might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Eyebright Flowering Aerial Parts Extract + Acarbose interactionAcetohexamideDymelor
How Acetohexamide interacts with Eyebright — through 1 ingredient. Tap an ingredient for the detail:
Eyebright Flowering Aerial Parts ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, eyebright might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Eyebright Flowering Aerial Parts Extract + Acetohexamide interactionAlbiglutideTanzeum
How Albiglutide interacts with Eyebright — through 1 ingredient. Tap an ingredient for the detail:
Eyebright Flowering Aerial Parts ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, eyebright might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Eyebright Flowering Aerial Parts Extract + Albiglutide interactionAlogliptinNesina
How Alogliptin interacts with Eyebright — through 1 ingredient. Tap an ingredient for the detail:
Eyebright Flowering Aerial Parts ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, eyebright might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Eyebright Flowering Aerial Parts Extract + Alogliptin interactionAlogliptin, MetforminKazano
How Alogliptin, Metformin interacts with Eyebright — through 1 ingredient. Tap an ingredient for the detail:
Eyebright Flowering Aerial Parts ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, eyebright might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Eyebright Flowering Aerial Parts Extract + Alogliptin, Metformin interactionAlogliptin, PioglitazoneOseni
How Alogliptin, Pioglitazone interacts with Eyebright — through 1 ingredient. Tap an ingredient for the detail:
Eyebright Flowering Aerial Parts ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, eyebright might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Eyebright Flowering Aerial Parts Extract + Alogliptin, Pioglitazone interactionAntidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) InhibitorGlyxambi
How Antidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) Inhibitor interacts with Eyebright — through 1 ingredient. Tap an ingredient for the detail:
Eyebright Flowering Aerial Parts ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, eyebright might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Eyebright Flowering Aerial Parts Extract + Antidiabetes, Dipeptidyl Peptidase-4 (dpp-iv) Inhibitor interactionCanagliflozinInvokana
How Canagliflozin interacts with Eyebright — through 1 ingredient. Tap an ingredient for the detail:
Eyebright Flowering Aerial Parts ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, eyebright might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Eyebright Flowering Aerial Parts Extract + Canagliflozin interactionCanagliflozin, MetforminInvokamet
How Canagliflozin, Metformin interacts with Eyebright — through 1 ingredient. Tap an ingredient for the detail:
Eyebright Flowering Aerial Parts ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, eyebright might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Eyebright Flowering Aerial Parts Extract + Canagliflozin, Metformin interactionCanagliflozin, Metformin HydrochlorideInvokamet XR
How Canagliflozin, Metformin Hydrochloride interacts with Eyebright — through 1 ingredient. Tap an ingredient for the detail:
Eyebright Flowering Aerial Parts ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, eyebright might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Eyebright Flowering Aerial Parts Extract + Canagliflozin, Metformin Hydrochloride interactionChlorpropamideChlorpropam, Diabinese
How Chlorpropamide interacts with Eyebright — through 1 ingredient. Tap an ingredient for the detail:
Eyebright Flowering Aerial Parts ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, eyebright might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Eyebright Flowering Aerial Parts Extract + Chlorpropamide interactionDapagliflozinFarxiga
How Dapagliflozin interacts with Eyebright — through 1 ingredient. Tap an ingredient for the detail:
Eyebright Flowering Aerial Parts ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, eyebright might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Eyebright Flowering Aerial Parts Extract + Dapagliflozin interactionDapagliflozin Propanediol, MetforminXigduo XR
How Dapagliflozin Propanediol, Metformin interacts with Eyebright — through 1 ingredient. Tap an ingredient for the detail:
Eyebright Flowering Aerial Parts ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, eyebright might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Eyebright Flowering Aerial Parts Extract + Dapagliflozin Propanediol, Metformin interactionDapagliflozin Propanediol, Saxagliptin HydrochlorideQtern
How Dapagliflozin Propanediol, Saxagliptin Hydrochloride interacts with Eyebright — through 1 ingredient. Tap an ingredient for the detail:
Eyebright Flowering Aerial Parts ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, eyebright might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Eyebright Flowering Aerial Parts Extract + Dapagliflozin Propanediol, Saxagliptin Hydrochloride interactionDapagliflozin, Metformin Hydrochloride, Saxagliptin HydrochlorideQternmet XR
How Dapagliflozin, Metformin Hydrochloride, Saxagliptin Hydrochloride interacts with Eyebright — through 1 ingredient. Tap an ingredient for the detail:
Eyebright Flowering Aerial Parts ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, eyebright might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Eyebright Flowering Aerial Parts Extract + Dapagliflozin, Metformin Hydrochloride, Saxagliptin Hydrochloride interactionDasiglucagon HydrochlorideZegalogue
How Dasiglucagon Hydrochloride interacts with Eyebright — through 1 ingredient. Tap an ingredient for the detail:
Eyebright Flowering Aerial Parts ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, eyebright might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Eyebright Flowering Aerial Parts Extract + Dasiglucagon Hydrochloride interactionDulaglutideTrulicity
How Dulaglutide interacts with Eyebright — through 1 ingredient. Tap an ingredient for the detail:
Eyebright Flowering Aerial Parts ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, eyebright might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Eyebright Flowering Aerial Parts Extract + Dulaglutide interactionEmpagliflozinJardiance
How Empagliflozin interacts with Eyebright — through 1 ingredient. Tap an ingredient for the detail:
Eyebright Flowering Aerial Parts ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, eyebright might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Eyebright Flowering Aerial Parts Extract + Empagliflozin interactionEmpagliflozin, Linagliptin, Metformin HydrochlorideTrijardy XR
How Empagliflozin, Linagliptin, Metformin Hydrochloride interacts with Eyebright — through 1 ingredient. Tap an ingredient for the detail:
Eyebright Flowering Aerial Parts ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, eyebright might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Eyebright Flowering Aerial Parts Extract + Empagliflozin, Linagliptin, Metformin Hydrochloride interactionEmpagliflozin, MetforminSynjardy
How Empagliflozin, Metformin interacts with Eyebright — through 1 ingredient. Tap an ingredient for the detail:
Eyebright Flowering Aerial Parts ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, eyebright might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Eyebright Flowering Aerial Parts Extract + Empagliflozin, Metformin interactionEmpagliflozin, Metformin HydrochlorideSynjardy XR
How Empagliflozin, Metformin Hydrochloride interacts with Eyebright — through 1 ingredient. Tap an ingredient for the detail:
Eyebright Flowering Aerial Parts ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, eyebright might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Eyebright Flowering Aerial Parts Extract + Empagliflozin, Metformin Hydrochloride interactionErtugliflozinSteglatro
How Ertugliflozin interacts with Eyebright — through 1 ingredient. Tap an ingredient for the detail:
Eyebright Flowering Aerial Parts ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, eyebright might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Eyebright Flowering Aerial Parts Extract + Ertugliflozin interactionErtugliflozin, Metformin HydrochlorideSegluromet
How Ertugliflozin, Metformin Hydrochloride interacts with Eyebright — through 1 ingredient. Tap an ingredient for the detail:
Eyebright Flowering Aerial Parts ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, eyebright might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Eyebright Flowering Aerial Parts Extract + Ertugliflozin, Metformin Hydrochloride interactionExenatideBydureon, Byetta
How Exenatide interacts with Eyebright — through 1 ingredient. Tap an ingredient for the detail:
Eyebright Flowering Aerial Parts ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, eyebright might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Eyebright Flowering Aerial Parts Extract + Exenatide interactionExenatide SyntheticBydureon BCISE
How Exenatide Synthetic interacts with Eyebright — through 1 ingredient. Tap an ingredient for the detail:
Eyebright Flowering Aerial Parts ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, eyebright might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Eyebright Flowering Aerial Parts Extract + Exenatide Synthetic interactionGliclazideDiamicron
How Gliclazide interacts with Eyebright — through 1 ingredient. Tap an ingredient for the detail:
Eyebright Flowering Aerial Parts ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, eyebright might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Eyebright Flowering Aerial Parts Extract + Gliclazide interactionGlimepirideAmaryl
How Glimepiride interacts with Eyebright — through 1 ingredient. Tap an ingredient for the detail:
Eyebright Flowering Aerial Parts ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, eyebright might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Eyebright Flowering Aerial Parts Extract + Glimepiride interactionGlipizideGlucotrol, Glucotrol XL
How Glipizide interacts with Eyebright — through 1 ingredient. Tap an ingredient for the detail:
Eyebright Flowering Aerial Parts ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, eyebright might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Eyebright Flowering Aerial Parts Extract + Glipizide interactionGlipizide, MetforminMetaglip
How Glipizide, Metformin interacts with Eyebright — through 1 ingredient. Tap an ingredient for the detail:
Eyebright Flowering Aerial Parts ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, eyebright might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Eyebright Flowering Aerial Parts Extract + Glipizide, Metformin interactionGlucagonBaqsimi, Glucagon
How Glucagon interacts with Eyebright — through 1 ingredient. Tap an ingredient for the detail:
Eyebright Flowering Aerial Parts ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, eyebright might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Eyebright Flowering Aerial Parts Extract + Glucagon interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Eyebright with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Eyebright Flowering Aerial Parts Extract
Antidiabetes Drugs
Theoretically, eyebright might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Animal research suggests that eyebright lowers blood glucose levels.
Brand information
Manufacturer and brand details for Eyebright, from the product label.
Herb Pharm
See all Herb Pharm products- Name
- Herb Pharm
- City
- Williams
- State
- OR
- ZipCode
- 97544
- Phone Number
- 800-348-4372
- Web Address
- www.herb-pharm.com
Eyebright by Herb Pharm: Common Questions
Does Eyebright by Herb Pharm interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Can I use eyebright while pregnant?
Is it safe to use eyebright while breastfeeding?
Can I put this liquid directly in my eye?
Does eyebright actually work for hay fever or colds?
What side effects might I notice if I take this orally?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Eyebright is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Eyebright’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Eyebright's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 4 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Eyebright 4 references
- Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
- Wichtl MW. Herbal Drugs and Phytopharmaceuticals. Ed. N.M. Bisset. Stuttgart: Medpharm GmbH Scientific Publishers, 1994.
- Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
- Porchezhian, E., Ansari, S. H., and Shreedharan, N. K. Antihyperglycemic activity of Euphrasia officinale leaves. Fitoterapia 2000;71(5):522-526. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC