False Unicorn (Helionum Root) 450 mg Ingredients & Drug Interactions
by TerraVita Premium Collection
What is this page for?
First and foremost: checking False Unicorn (Helionum Root) 450 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
False Unicorn (Helionum Root) 450 mg is a dietary supplement by TerraVita Premium Collection with 1 active ingredient. Its ingredients are commonly taken for menstrual cramps, menopausal symptoms, female infertility support.Based on those ingredients, 740 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are False Unicorn. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against False Unicorn (Helionum Root) 450 mg by TerraVita Premium Collection
Ask about any prescription or over-the-counter medication and we check it for interactions with False Unicorn (Helionum Root) 450 mg by TerraVita Premium Collection — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of False Unicorn (Helionum Root) 450 mg by TerraVita Premium Collection
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: False Unicorn root, 450 mg per capsule. The capsule itself is made from gelatin and water.
Does it work?
Couldn't assess
The product facts we hold contain no effectiveness ratings for false unicorn, so we cannot speak to how well it works for any purpose.
How safe is it?
Well-documented data
False unicorn root is generally well tolerated when taken by mouth, though large doses have been reported to cause nausea and vomiting. Safety data in humans is limited, and high doses may cause stomach upset.
False unicorn should be avoided in pregnancy — it has traditional use tied to effects on the uterus, and safety data is lacking. It should also be avoided while breastfeeding due to insufficient safety information.
If you're pregnant, planning pregnancy, or breastfeeding, talk with your pharmacist or doctor before taking this product.
Meds to double-check
Moderate interaction found
Before taking this product, double-check your medications against these drug types: CYP2D6 substrates (including certain antidepressants, opioids, and heart rhythm drugs), CYP3A4 substrates (including calcium channel blockers and chemotherapy agents), and lithium. Use the medication checker on this page with your exact prescriptions.
The bottom line
Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
False Unicorn may be of interest to those seeking traditional herbal support, but it interacts significantly with medications via liver enzymes and lithium. If you take any prescription drugs — especially antidepressants, pain relievers, heart medications, chemotherapy, or lithium — check with your pharmacist first.
Avoid it if you're pregnant or breastfeeding.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Mar 22, 2023.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about False Unicorn (Helionum Root) 450 mg, straight from the product label.
| Brand | TerraVita Premium Collection |
|---|---|
| Barcode (UPC) | 064435166588 |
| Net contents | 100 Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Mar 22, 2023 |
| DSLD ID | 287584 |
| Product type | Botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for False Unicorn (Helionum Root) 450 mg by TerraVita Premium Collection, sourced from the NIH Dietary Supplement Label Database.
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity
A Dietary Supplement
Brand IP Statement(s)
Copyright 2006 TerraVita - Distributed by ZooScape LLC, All Rights Reserved.
Suggested/Recommended/Usage/Directions
Directions Take 1 capsule, 3 times daily, with meals.
General Statements
TerraVita is an exclusive line of premium natural products that use the finest, purest and most potent ingredients in the world. TerraVita's hallmarks are the highest possible standards of purity, potency, stability and freshness. All products are prepared with the greatest quality control, from raw materials through the entire manufacturing process, right up to the moment your product is sealed for freshness and shipped to you.
Please recycle!
FDA Disclaimer Statement
Statements not evaluated by FDA. Product not intended to diagnose, treat, cure, or prevent any disease.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
False Unicorn (Helionum Root) 450 mg by TerraVita Premium Collection label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in False Unicorn (Helionum Root) 450 mg by TerraVita Premium Collection
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 Capsule(s) Dosage formCapsule Servings per container100 Amounts shown are per serving.
False Unicorn
Interacts with740 drugs
False Unicorn is a North American plant whose root has long been used in traditional medicine for women's reproductive and menstrual concerns. There i...
False Unicorn monograph & interactionsOther (inactive) ingredients: Gelatin, Water. These complete the product’s ingredient list but are not active constituents.
False Unicorn (Helionum Root) 450 mg by TerraVita Premium Collection Drug Interactions
HelloPharmacist Interaction Report
False Unicorn by TerraVita Premium Collection does interact with medications.
The main concern is that false unicorn can slow how your liver breaks down certain drugs, potentially raising their levels in your bloodstream.
Read the full breakdown — every affected drug type, severity by severity
The ingredient inhibits two major liver enzymes — CYP2D6 and CYP3A4 — both Moderate severity. CYP2D6 substrates affected include some antidepressants (amitriptyline, desipramine), opioids like codeine and fentanyl, heart rhythm drugs (flecainide), and others like donepezil and clozapine.
CYP3A4 substrates include some blood pressure medications (calcium channel blockers like diltiazem, verapamil, nicardipine), chemotherapy drugs (paclitaxel, vincristine, vinblastine, etoposide, vindesine), and others. False unicorn also has diuretic (fluid-shedding) properties that may theoretically reduce how your body clears lithium, raising its level — a Moderate concern.
Altogether, these interactions span 730 individual medications. Use the medication checker on this page with your exact prescriptions before you start.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against False Unicorn (Helionum Root) 450 mg?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in False Unicorn (Helionum Root) 450 mg interact with 740 drugs. Click any drug to see the details.
1 of the 1 ingredient in False Unicorn (Helionum Root) 450 mg interact with drugs. Each result below shows which ingredient is responsible. False Unicorn
Ado-trastuzumab EmtansineKadcyla
How Ado-trastuzumab Emtansine interacts with False Unicorn (Helionum Root) 450 mg — through 1 ingredient. Tap an ingredient for the detail:
False UnicornCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
In vitro, false unicorn extract inhibits cytochrome P450 3A4 (CYP3A4) activity.
Read the full False Unicorn + Ado-trastuzumab Emtansine interactionAbemaciclibVerzenio
How Abemaciclib interacts with False Unicorn (Helionum Root) 450 mg — through 1 ingredient. Tap an ingredient for the detail:
False UnicornCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
In vitro, false unicorn extract inhibits cytochrome P450 3A4 (CYP3A4) activity.
Read the full False Unicorn + Abemaciclib interactionAbiraterone
How Abiraterone interacts with False Unicorn (Helionum Root) 450 mg — through 1 ingredient. Tap an ingredient for the detail:
False UnicornCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
In vitro, false unicorn extract inhibits cytochrome P450 3A4 (CYP3A4) activity.
Read the full False Unicorn + Abiraterone interactionAbiraterone AcetateYonsa, Zytiga
How Abiraterone Acetate interacts with False Unicorn (Helionum Root) 450 mg — through 1 ingredient. Tap an ingredient for the detail:
False UnicornCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
In vitro, false unicorn extract inhibits cytochrome P450 3A4 (CYP3A4) activity.
Read the full False Unicorn + Abiraterone Acetate interactionAcalabrutinibCalquence
How Acalabrutinib interacts with False Unicorn (Helionum Root) 450 mg — through 1 ingredient. Tap an ingredient for the detail:
False UnicornCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
In vitro, false unicorn extract inhibits cytochrome P450 3A4 (CYP3A4) activity.
Read the full False Unicorn + Acalabrutinib interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with False Unicorn (Helionum Root) 450 mg — through 1 ingredient. Tap an ingredient for the detail:
False UnicornCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
In vitro, false unicorn extract inhibits cytochrome P450 3A4 (CYP3A4) activity.
Read the full False Unicorn + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with False Unicorn (Helionum Root) 450 mg — through 1 ingredient. Tap an ingredient for the detail:
False UnicornCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
In vitro, false unicorn extract inhibits cytochrome P450 3A4 (CYP3A4) activity.
Read the full False Unicorn + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with False Unicorn (Helionum Root) 450 mg — through 1 ingredient. Tap an ingredient for the detail:
False UnicornCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
In vitro, false unicorn extract inhibits cytochrome P450 3A4 (CYP3A4) activity.
Read the full False Unicorn + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Butalbital, CodeineBancap w/ Codeine
How Acetaminophen, Butalbital, Codeine interacts with False Unicorn (Helionum Root) 450 mg — through 1 ingredient. Tap an ingredient for the detail:
False UnicornCytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
In vitro, false unicorn extract inhibits cytochrome P450 2D6 (CYP2D6) activity.
Read the full False Unicorn + Acetaminophen, Butalbital, Codeine interactionAcetaminophen, Butalbital, Codeine PhosphatePhrenilin #3
How Acetaminophen, Butalbital, Codeine Phosphate interacts with False Unicorn (Helionum Root) 450 mg — through 1 ingredient. Tap an ingredient for the detail:
False UnicornCytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
In vitro, false unicorn extract inhibits cytochrome P450 2D6 (CYP2D6) activity.
Read the full False Unicorn + Acetaminophen, Butalbital, Codeine Phosphate interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with False Unicorn (Helionum Root) 450 mg — through 1 ingredient. Tap an ingredient for the detail:
False UnicornCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
In vitro, false unicorn extract inhibits cytochrome P450 2D6 (CYP2D6) activity.
Read the full False Unicorn + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with False Unicorn (Helionum Root) 450 mg — through 1 ingredient. Tap an ingredient for the detail:
False UnicornCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
In vitro, false unicorn extract inhibits cytochrome P450 2D6 (CYP2D6) activity.
Read the full False Unicorn + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with False Unicorn (Helionum Root) 450 mg — through 1 ingredient. Tap an ingredient for the detail:
False UnicornCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
In vitro, false unicorn extract inhibits cytochrome P450 2D6 (CYP2D6) activity.
Read the full False Unicorn + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with False Unicorn (Helionum Root) 450 mg — through 1 ingredient. Tap an ingredient for the detail:
False UnicornCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
In vitro, false unicorn extract inhibits cytochrome P450 3A4 (CYP3A4) activity.
Read the full False Unicorn + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Caffeine, IsomethepteneMigralam
How Acetaminophen, Caffeine, Isometheptene interacts with False Unicorn (Helionum Root) 450 mg — through 1 ingredient. Tap an ingredient for the detail:
False UnicornCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
In vitro, false unicorn extract inhibits cytochrome P450 3A4 (CYP3A4) activity.
Read the full False Unicorn + Acetaminophen, Caffeine, Isometheptene interactionAcetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with False Unicorn (Helionum Root) 450 mg — through 1 ingredient. Tap an ingredient for the detail:
False UnicornCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
In vitro, false unicorn extract inhibits cytochrome P450 3A4 (CYP3A4) activity.
Read the full False Unicorn + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, Chlorpheniramine Maleate, Dextromethorphan HbrVicks Formula 44M Cough, Cold & Flu Relief
How Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interacts with False Unicorn (Helionum Root) 450 mg — through 1 ingredient. Tap an ingredient for the detail:
False UnicornCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
In vitro, false unicorn extract inhibits cytochrome P450 2D6 (CYP2D6) activity.
Read the full False Unicorn + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionAcetaminophen, Chlorpheniramine, Codeine, PhenylephrineColrex
How Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interacts with False Unicorn (Helionum Root) 450 mg — through 1 ingredient. Tap an ingredient for the detail:
False UnicornCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
In vitro, false unicorn extract inhibits cytochrome P450 3A4 (CYP3A4) activity.
Read the full False Unicorn + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, DextromethorphanCoricidin II Extra Strength Cold and Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan interacts with False Unicorn (Helionum Root) 450 mg — through 1 ingredient. Tap an ingredient for the detail:
False UnicornCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
In vitro, false unicorn extract inhibits cytochrome P450 2D6 (CYP2D6) activity.
Read the full False Unicorn + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionAcetaminophen, Chlorpheniramine, Dextromethorphan HydrobromideCoricidin HBP Maximum Strength Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interacts with False Unicorn (Helionum Root) 450 mg — through 1 ingredient. Tap an ingredient for the detail:
False UnicornCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
In vitro, false unicorn extract inhibits cytochrome P450 3A4 (CYP3A4) activity.
Read the full False Unicorn + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PhenylpropanolamineMulti Symptom Cold Relief
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interacts with False Unicorn (Helionum Root) 450 mg — through 1 ingredient. Tap an ingredient for the detail:
False UnicornCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
In vitro, false unicorn extract inhibits cytochrome P450 2D6 (CYP2D6) activity.
Read the full False Unicorn + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PseudoephedrineChildren's Tylenol Cold Plus Cough, Tylenol Cold Ex Strength
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interacts with False Unicorn (Helionum Root) 450 mg — through 1 ingredient. Tap an ingredient for the detail:
False UnicornCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
In vitro, false unicorn extract inhibits cytochrome P450 3A4 (CYP3A4) activity.
Read the full False Unicorn + Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interactionAcetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, SalicylamideRhinogesic GG
How Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interacts with False Unicorn (Helionum Root) 450 mg — through 1 ingredient. Tap an ingredient for the detail:
False UnicornCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
In vitro, false unicorn extract inhibits cytochrome P450 3A4 (CYP3A4) activity.
Read the full False Unicorn + Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interactionAcetaminophen, Chlorpheniramine, PhenylephrineAlka-Seltzer PLUS, Histex SR, Protid
How Acetaminophen, Chlorpheniramine, Phenylephrine interacts with False Unicorn (Helionum Root) 450 mg — through 1 ingredient. Tap an ingredient for the detail:
False UnicornCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
In vitro, false unicorn extract inhibits cytochrome P450 3A4 (CYP3A4) activity.
Read the full False Unicorn + Acetaminophen, Chlorpheniramine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, Phenylephrine, SalicylamideRhinogesic, Rhinogesic JR
How Acetaminophen, Chlorpheniramine, Phenylephrine, Salicylamide interacts with False Unicorn (Helionum Root) 450 mg — through 1 ingredient. Tap an ingredient for the detail:
False UnicornCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
In vitro, false unicorn extract inhibits cytochrome P450 3A4 (CYP3A4) activity.
Read the full False Unicorn + Acetaminophen, Chlorpheniramine, Phenylephrine, Salicylamide interactionAcetaminophen, Chlorpheniramine, PhenylpropanolamineAlumadrine, Conex, Sinadrin Max Strength, Sinulin
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine interacts with False Unicorn (Helionum Root) 450 mg — through 1 ingredient. Tap an ingredient for the detail:
False UnicornCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
In vitro, false unicorn extract inhibits cytochrome P450 3A4 (CYP3A4) activity.
Read the full False Unicorn + Acetaminophen, Chlorpheniramine, Phenylpropanolamine interactionAcetaminophen, Chlorpheniramine, Phenylpropanolamine, OpiumHista-Derfule
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Opium interacts with False Unicorn (Helionum Root) 450 mg — through 1 ingredient. Tap an ingredient for the detail:
False UnicornCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
In vitro, false unicorn extract inhibits cytochrome P450 3A4 (CYP3A4) activity.
Read the full False Unicorn + Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Opium interactionAcetaminophen, Chlorpheniramine, Phenylpropanolamine, PhenyltoloxamineNorel Plus
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Phenyltoloxamine interacts with False Unicorn (Helionum Root) 450 mg — through 1 ingredient. Tap an ingredient for the detail:
False UnicornCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
In vitro, false unicorn extract inhibits cytochrome P450 3A4 (CYP3A4) activity.
Read the full False Unicorn + Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Phenyltoloxamine interactionAcetaminophen, Chlorpheniramine, PseudoephedrineAlka-Seltzer PLUS Liquid Gels, Children's Tylenol Cold, Codimal, Comtrex, Extra Strength Tylenol Allergy Sinus, Lorsin +3 more
How Acetaminophen, Chlorpheniramine, Pseudoephedrine interacts with False Unicorn (Helionum Root) 450 mg — through 1 ingredient. Tap an ingredient for the detail:
False UnicornCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
In vitro, false unicorn extract inhibits cytochrome P450 3A4 (CYP3A4) activity.
Read the full False Unicorn + Acetaminophen, Chlorpheniramine, Pseudoephedrine interactionAcetaminophen, Chlorzoxazone, CodeineAcetazone Forte C8, Parafon Forte C8
How Acetaminophen, Chlorzoxazone, Codeine interacts with False Unicorn (Helionum Root) 450 mg — through 1 ingredient. Tap an ingredient for the detail:
False UnicornCytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
In vitro, false unicorn extract inhibits cytochrome P450 2D6 (CYP2D6) activity.
Read the full False Unicorn + Acetaminophen, Chlorzoxazone, Codeine interactionEach ingredient & the kinds of drugs it affects
For each ingredient in False Unicorn (Helionum Root) 450 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
False Unicorn
Cytochrome P450 2D6 (Cyp2D6) Substrates
In vitro, false unicorn extract inhibits cytochrome P450 2D6 (CYP2D6) activity. Theoretically, false unicorn might increase the levels of CYP2D6 substrates. Some of drugs that are CYP2D6 substrates include amitriptyline (Elavil), clozapine (Clozaril), codeine, desipramine (Norpramin), donepezil (Aricept), fentanyl (Duragesic), flecainide (Tambocor), fluoxetine (Prozac), meperidine (Demerol), methadone (Dolophine), metoprolol (Lopressor, Toprol XL), olanzapine (Zyprexa), ondansetron (Zofran), tramadol (Ultram), trazodone (Desyrel), and others.
Cytochrome P450 3A4 (Cyp3A4) Substrates
In vitro, false unicorn extract inhibits cytochrome P450 3A4 (CYP3A4) activity. Theoretically, false unicorn might increase the levels of CYP3A4 substrates. Drugs that might be affected include some calcium channel blockers (diltiazem, nicardipine, verapamil), chemotherapeutic agents (etoposide, paclitaxel, vinblastine, vincristine, vindesine), antifungals (ketoconazole, itraconazole), glucocorticoids, cisapride (Propulsid), alfentanil (Alfenta), fentanyl (Sublimaze), losartan (Cozaar), fluoxetine (Prozac), midazolam (Versed), omeprazole (Prilosec), ondansetron (Zofran), propranolol (Inderal), fexofenadine (Allegra), and numerous others.
Lithium
False unicorn is thought to have diuretic properties. Theoretically, due to these potential diuretic effects, false unicorn might reduce excretion and increase levels of lithium. The dose of lithium might need to be decreased.
Brand information
Manufacturer and brand details for False Unicorn (Helionum Root) 450 mg, from the product label.
TerraVita Premium Collection
See all TerraVita Premium Collection products- Name
- TerraVita Fine Whole Herbs
- City
- Brampton
- State
- Ontario
False Unicorn (Helionum Root) 450 mg by TerraVita Premium Collection: Common Questions
Does False Unicorn (Helionum Root) 450 mg by TerraVita Premium Collection interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Can I take False Unicorn if I'm pregnant or breastfeeding?
What are the side effects?
Why does this product interact with so many medications?
Is this product FDA approved?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if False Unicorn (Helionum Root) 450 mg is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind False Unicorn (Helionum Root) 450 mg’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
False Unicorn (Helionum Root) 450 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 4 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
False Unicorn 4 references
- Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
- McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
- Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
- Ho SH, Singh M, Holloway AC, Crankshaw DJ. The effects of commercial preparations of herbal supplements commonly used by women on the biotransformation of fluorogenic substrates by human cytochromes P450. Phytother Res. 2011;25(7):983-9. PubMed
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