Interactions on record — worth a quick check against your medications. Based on 1 of 5 ingredients. Check your meds →
Dietary supplement

Fast Acting Enzymes + Daily Probiotic Ingredients & Drug Interactions

by Schiff Digestive Advantage

Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Fast Acting Enzymes + Daily Probiotic is a dietary supplement by Schiff Digestive Advantage with 5 active ingredients. Its ingredients are commonly taken for constipation, irritable bowel syndrome (ibs), diarrhea.Based on those ingredients, 182 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Bacillus coagulans GBI-30 6086. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Fast Acting Enzymes + Daily Probiotic by Schiff Digestive Advantage

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 5 active ingredients.

This product contains five active ingredients, each a digestive enzyme or probiotic. Bacillus coagulans GBI-30 6086 is a live probiotic organism that may support gut function.

Hemicellulase, alpha-galactosidase, cellulase, and invertase are digestive enzymes — proteins that break down different kinds of carbohydrates and fiber in food to make them easier for your body to absorb. The remaining ingredients are inactive — fillers and binders that give the capsule its form and stability.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: digestive support and bloating relief.
  • We looked for evidence on: Constipation, Flatulence, Irritable bowel syndrome (IBS), Dyspepsia, Gas, Abdominal discomfort — and 1 related terms.
  • The strongest evidence on file: Bacillus Coagulans is rated "Possibly Effective" for Constipation (Natural Medicines).
  • Also on file: Bacillus Coagulans is rated "Possibly Effective" for Irritable bowel syndrome (IBS).
  • Also on file: Bacillus Coagulans is rated "Insufficient Reliable Evidence To Rate" for Dyspepsia, Flatulence.

Bacillus coagulans is possibly effective for constipation and for irritable bowel syndrome (IBS). For antibiotic-associated diarrhea, athletic performance, cancer, and nonalcoholic fatty liver disease, the evidence isn't strong enough to rate it one way or the other.

We don't hold effectiveness ratings for the enzymes (hemicellulase, alpha-galactosidase, cellulase, and invertase) in our data.

The evidence, ingredient by ingredient Bacillus Coagulans

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Bacillus coagulans is generally well tolerated in healthy adults, though the quality and safety data for probiotic products vary. That said, there isn't enough reliable safety information overall, so talk to your doctor before starting.

There is a theoretical concern that live probiotic organisms could cause infection in people with severely weakened immune systems, central lines, or other serious illness — though this risk is very low in people with healthy, intact immune systems. The pregnancy and lactation safety data for Bacillus coagulans isn't on file for us; ask your doctor or pharmacist for personalized advice if you're pregnant or breastfeeding.

Side effects, ingredient by ingredient Bacillus Coagulans

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Bacillus Coagulans.
  • The most serious interaction on file is rated Moderate.
  • For scale: 182 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your doctor or pharmacist before combining this product with antibiotics. Antibiotics are the only drug type with documented interactions with Bacillus coagulans in our data.

Separate the timing so the antibiotic doesn't reduce the probiotic's effectiveness.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This product may help with constipation or IBS symptoms through its probiotic. If you take antibiotics, time them separately from the probiotic so the antibiotic doesn't kill the live organisms.

Talk with your doctor or pharmacist before starting, especially if you have a weakened immune system or are pregnant or breastfeeding.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 5 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Apr 11, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Fast Acting Enzymes + Daily Probiotic, straight from the product label.

Brand Schiff Digestive Advantage
Net contents 40 Capsule(s)
Market status On market
Date entered into DSLD Apr 11, 2022
DSLD ID 261786
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Children 4 or More Years of Age, Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Fast Acting Enzymes + Daily Probiotic by Schiff Digestive Advantage, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
40
IngredientAmount% DV
Hemicellulase0 NP--
Alpha-Galactosidase0 NP--
Bacillus coagulans GBI-30 60860 NP--
Cellulase0 NP--
Invertase0 NP--

Other ingredients: Maltodextrin, Hypromellose, Microcrystalline Cellulose, Dextrin, Citric Acid, Titanium Dioxide, Sodium Benzoate, Silicon Dioxide, Magnesium Stearate, Mannitol, Calcium Gluconate, ground Limestone

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)

Schiff Since 1936

Copyright 2017 RB Health, Hygiene, Home

Formulation

Proactive Digestive Support

Fast Acting Enzymes Supports Breakdown of Hard-to-Digest Carbohydrates Helps prevent gas Daily Probiotic Helps Reduce Bloating & Abdominal Discomfort

To support overall digestive health, choose digestive advantage fast acting enzymes + daily probiotic!

Digestive Advantage Fast Acting Enzymes Plus Daily Probiotic contains powerful ingredients. The Enzymes help you break down hard to digest carbohydrates, while the Daily Probiotic helps lessen abdominal discomfort and bloating while helping to reduce occasional diarrhea. Together, this will allow you to see short-term and long term digestive benefits Why Digestive Advantage? Many probiotics don't survive through the stomach acid. Digestive Advantage does; it survives through the stomach's harsh environment 100x better than leading probiotics & yogurt. Why does Digestive Advantage survive? The unique probiotic, BC30, that is used only in Digestive Advantage, is naturally protected by a layer of protein. This protection allows it to survive through the stomach's acid. It can then reach the intestines where you need it most in order to promote digestive and immune health.

Enjoy the Benefits Fast acting enzymes Helps stop intestinal gas before it starts Promotes long-term digestive health with continued use Just one capsule daily

Studies reveal that the single strain of probiotic used in Schiff Digestive Advantage survives 100x better than other probiotics and yogurts to deliver good bacteria where you need it.

Guaranteed: No added sugar (sucrose, fructose), salt (sodium chloride). No artificial flavors.

Based on median % survivability of Digestive Advantage vs. probiotic supplements and 19 probiotic yogurts in simulated gastric pH for 2 hours. Survivability and delivery of probiotic cells to the small & large intestines is one of several factors influencing overall product effect.

Gluten Free.

Formula

Probiotic survives stomach acid 100X better

Powered by Ganeden BC 30 Probiotic Digestive & Immune Health

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Directions Adults: Take one (1) capsule daily with water before problem foods. Some individuals may require taking two (2) or more capsules daily depending on intake of problem food. Do not take more than three (3) capsules daily. Children 8 years and over: For children it is recommended that one (1) capsule be opended and contents mixed into food or drink. Upon initial use, it may take 7 to 14 days for you to feel the product working. Consistent, daily use is needed to maintain results.

Precautions

Contains milk, soy and wheat.

If pregnant, breastfeeding, or on medication, consult your physician before using this product.

Keep out of reach of children. Always consult your pediatrician before giving your child dietary supplements. Galactosemics - Consult your physician.

Do not use if carton is damaged or if printed seal on blister is broken or missing.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Seals/Symbols

Schiff Quality Guarantee Guaranteed for purity, freshness and labeled potency.

Storage

Store in a cool, dry place and avoid excessive heat.

See for yourself

Fast Acting Enzymes + Daily Probiotic by Schiff Digestive Advantage label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Fast Acting Enzymes + Daily Probiotic by Schiff Digestive Advantage

These are the 5 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container40 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Hemicellulase

0 NP per serving Form: Aspergillus niger

Alpha-Galactosidase

0 NP per serving Form: Aspergillus niger

Bacillus coagulans GBI-30 6086

Interacts with
182 drugs
0 NP per serving

Bacillus coagulans is a spore-forming probiotic that survives stomach acid well and may help with some digestive problems such as IBS, constipation, a...

Bacillus coagulans GBI-30 6086 monograph & interactions

Cellulase

0 NP per serving Form: Aspergillus niger

Invertase

0 NP per serving Form: Saccharomyces cerevisiae

Other (inactive) ingredients: Maltodextrin, Hypromellose, Microcrystalline Cellulose, Dextrin, Citric Acid, Titanium Dioxide, Sodium Benzoate, Silicon Dioxide, Magnesium Stearate, Mannitol, Calcium Gluconate, Ground Limestone. These complete the product’s ingredient list but are not active constituents.

Interaction report

Fast Acting Enzymes + Daily Probiotic by Schiff Digestive Advantage Drug Interactions

Want to check YOUR meds against Fast Acting Enzymes + Daily Probiotic?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
182Drugs
182 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Fast Acting Enzymes + Daily Probiotic with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Bacillus coagulans GBI-30 60861 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B. coagulans.
B. coagulans preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and B. coagulans preparations by at least two hours.

Likelihood Probable Evidence D
The maker

Brand information

Manufacturer and brand details for Fast Acting Enzymes + Daily Probiotic, from the product label.

Schiff Digestive Advantage

See all Schiff Digestive Advantage products
Name
Reckitt Benckiser
City
Parsippany
State
NJ
ZipCode
07054-0224
Phone Number
1-800-526-6251
Web Address
www.DigestiveAdvantage.com
Pharmacist Counseling Corner

Fast Acting Enzymes + Daily Probiotic by Schiff Digestive Advantage: Common Questions

Does Fast Acting Enzymes + Daily Probiotic by Schiff Digestive Advantage interact with any medications?
Yes. Based on its ingredients, Fast Acting Enzymes + Daily Probiotic has a known interaction with 182 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Fast Acting Enzymes + Daily Probiotic contains 5 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this help my IBS?
Bacillus coagulans in this product is possibly effective for IBS. That means the evidence suggests it may help, but it's not guaranteed to work for everyone. Talk to your doctor if your symptoms don't improve or get worse.
Can I take this if I'm on an antibiotic?
You can, but don't take them at the same time. Antibiotics can kill the live organisms in the probiotic and make it less effective. Separate them by a few hours — ask your pharmacist for the best timing with your specific antibiotic.
What do the digestive enzymes in this do?
They break down carbohydrates and fiber in your food so your body can absorb them more easily. The four enzymes work together to handle different types of carbs and plant material.
Is this safe if I'm pregnant?
We don't have enough safety data for Bacillus coagulans in pregnancy. Talk to your doctor or pharmacist before taking it if you're pregnant or breastfeeding — they can give you personalized advice based on your situation.
Does this have fillers?
Yes, it contains several inactive ingredients like maltodextrin, microcrystalline cellulose, and magnesium stearate, which are standard binders and flow agents in capsules.
Is this safe for people with weakened immune systems?
Probiotic products that contain live organisms carry a very small theoretical risk in severely ill or immunocompromised people. If your immune system is weak or you have a central line, check with your doctor before using this.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Fast Acting Enzymes + Daily Probiotic is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Fast Acting Enzymes + Daily Probiotic label
Go deeper

The Full Monographs Behind Fast Acting Enzymes + Daily Probiotic’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Fast Acting Enzymes + Daily Probiotic's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 20 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Bacillus Coagulans 20 references
  1. Saxelin M, Chuang NH, Chassy B, et al. Lactobacilli and bacteremia in southern Finland 1989-1992. Clin Infect Dis 1996;22:564-6. PubMed
  2. Tynkkynen S, Singh KV, Varmanen P. Vancomycin resistance factor of Lactobacillus rhamnosus GG in relation to enterococcal vancomycin resistance (van) genes. Int J Food Microbiol 1998;41:195-204. PubMed
  3. Klein G, Zill E, Schindler R, et al. Peritonitis associated with vancomycin-resistant Lactobacillus rhamnosus in a continuous ambulatory peritoneal dialysis patient; organism identification, antibiotic therapy, and case report. J Clin Microbiol 1998;36:
  4. Kalima P, Masterton RG, Roddie PH, et al. Lactobacillus rhamnosus infection in a child following bone marrow transplant. J Infect 1996;32:165-7. PubMed
  5. Goldin BR. Health Benefits of probiotics. Br J Nutr 1998;80:S203-7. DOI
  6. Rautio M, Jousimies-Somer H, Kauma H, et al. Liver abscess due to Lactobacillus rhamnosus strain indistinguishable from L. rhamnosus strain GG. Clin Infect Dis 1999;28:1159-60.
  7. MacGregor G, Smith AJ, Thakker B, Kinsella J. Yoghurt biotherapy: contraindicated in immunosuppressed patients? Postgrad Med J 2002;78:366-7. PubMed
  8. Land MH, Rouster-Stevens K, Woods CR, et al. Lactobacillus sepsis associated with probiotic therapy. Pediatrics 2005;115:178-81.
  9. De Groote MA, Frank DN, Dowell E, et al. Lactobacillus rhamnosus GG bacteremia associated with probiotic use in a child with short gut syndrome. Pediatr Infect Dis J 2005;24:278-80. PubMed
  10. Vahabnezhad E, Mochon AB, Wozniak LJ, Ziring DA. Lactobacillus bacteremia associated with probiotic use in a pediatric patient with ulcerative colitis. J Clin Gastroenterol. 2013;47(5):437-9. PubMed
  11. Pruccoli G, Silvestro E, Pace Napoleone C, Aidala E, Garazzino S, Scolfaro C. Are probiotics safe? Bifidobacterium bacteremia in a child with severe heart failure. Infez Med. 2019;27(2):175-178.
  12. Sendil S, Shrimanker I, Mansoora Q, Goldman J, Nookala VK. Lactobacillus rhamnosus bacteremia in an immunocompromised renal transplant patient. Cureus. 2020;12(2):e6887. PubMed
  13. Albarillo FS, Shah U, Joyce C, Slade D. Lactobacillus rhamnosus Infection: A single-center 4-year descriptive analysis. J Glob Infect Dis. 2020;12(3):119-123. PubMed
  14. Pasala S, Singer L, Arshad T, Roach K. Lactobacillus endocarditis in a healthy patient with probiotic use. IDCases. 2020;22:e00915. PubMed
  15. Agrawal S, Tuchman ES, Bruce MJ, Theodorou ME. Fatal Lactobacillus endocarditis in a patient with transcatheter aortic valve replacement. BMJ Case Rep. 2020;13(11):e236835.
  16. Antoun M, Hattab Y, Akhrass FA, Hamilton LD. Uncommon pathogen, Lactobacillus, causing infective endocarditis: Case report and review. Case Rep Infect Dis. 2020;2020:8833948. PubMed
  17. Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
  18. Franko B, Vaillant M, Recule C, Vautrin E, et al. Lactobacillus paracasei endocarditis in a consumer of probiotics. Med Mal Infect. 2013;43(4):171-3. PubMed
  19. Campbell RE, Miller A, Afroze A. Native valve endocarditis secondary to Lactobacillus paracasei bacteremia. Consultant. 2020;60(9):27-8. DOI
  20. Kato K, Funabashi N, Takaoka H, et al. Lactobacillus paracasei endocarditis in a consumer of probiotics with advanced and severe bicuspid aortic valve stenosis complicated with diffuse left ventricular mid-layer fibrosis. Int J Cardiol. 2016;224:157-161. PubMed

See these in context on the Bacillus Coagulans monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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