Fertile Fields Teapills Ingredients & Drug Interactions
by Plum Flower
What is this page for?
First and foremost: checking Fertile Fields Teapills against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Fertile Fields Teapills is a dietary supplement by Plum Flower with 10 active ingredients. Its ingredients are commonly taken for menopause symptoms, menstrual cramps and irregular periods, premenstrual syndrome (pms).Based on those ingredients, 1,259 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Scutellaria baicalensis Root Extract, Paeonia lactiflora Root Extract, Rehmannia glutinosa Root Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Fertile Fields Teapills by Plum Flower
Ask about any prescription or over-the-counter medication and we check it for interactions with Fertile Fields Teapills by Plum Flower — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Fertile Fields Teapills by Plum Flower
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
Fertile Fields Teapills contains 10 active ingredients, most of them botanical extracts drawn from traditional Chinese medicine: dong quai root, rehmannia root, Baikal skullcap root, Eucommia bark, nutgrass rhizome, lovage rhizome, Dipsacus root, mugwort leaf, donkey gelatin, and peony root. Each plays a role in the traditional herbal formulation, though the product's actual effectiveness for its stated purposes hasn't been reliably established in modern research.
The tablet also contains inactive ingredients—microcrystalline cellulose, hydrated magnesium silicate, maltose, and China wax—which are binders and fillers that hold the pill together.
Does it work?
Not established
The data we hold shows insufficient reliable evidence to rate most of what Fertile Fields Teapills is used for—iron deficiency anemia, osteoporosis, heart disease, migraines, and eczema all fall into that category for dong quai and several other ingredients. Rehmannia is rated possibly effective for chronic kidney disease, one of the few positive effectiveness ratings in this formula.
Gelatin is rated possibly ineffective for diarrhea. Overall, this is a traditional herbal blend with limited modern research backing its specific health claims.
How safe is it?
Well-documented data
Most of the individual ingredients are generally well tolerated when used orally, though side effects can occur. Dong quai may cause burping and flatulence, and it can make your skin more sensitive to sunlight, so use with care.
Baikal skullcap can trigger abdominal pain, constipation, diarrhea, nausea, or vomiting in some people; rare cases of liver inflammation and a serious lung condition called hypersensitivity pneumonitis have been reported with one branded product containing Baikal skullcap. Peony may cause abdominal bloating, loss of appetite, diarrhea, or nausea.
Gelatin can cause belching, bloating, and indigestion, and allergic reactions including hives and in rare cases anaphylaxis are possible. None of these ingredients have adequate safety data in pregnancy—dong quai may stimulate the uterus and affect bleeding—or breastfeeding.
Talk to your doctor or pharmacist before using this product if you're pregnant, nursing, or planning to become pregnant.
Meds to double-check
Major interaction found
Before taking Fertile Fields Teapills, double-check your medications with a pharmacist, especially: blood thinners and antiplatelet drugs (Major and Moderate risk of bleeding from dong quai and multiple other ingredients), blood pressure medications (Moderate risk of extra-low blood pressure from rehmannia and Baikal skullcap), diabetes medications (Moderate risk of low blood sugar from rehmannia and Baikal skullcap), estrogen-based hormone therapy and birth control (Moderate risk of reduced effectiveness from dong quai, Baikal skullcap, and peony), lithium mood stabilizers (Moderate risk of toxicity from Baikal skullcap), antithyroid medications (Moderate risk of over-suppression from Baikal skullcap), and certain liver-metabolized drugs including some antidepressants, heart medications, clozapine, and phenytoin (Moderate risks from Baikal skullcap and peony).
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. Major medication interactions have been identified, and safety information is well characterized.
Fertile Fields Teapills is a multi-ingredient herbal formula with strong interaction potential, especially if you take blood thinners, blood pressure or diabetes medications, birth control, hormone therapy, mood stabilizers, or seizure medications. The effectiveness for most of its traditional uses hasn't been proven in modern research.
If you're interested in this product, bring your complete medication list to your pharmacist first—a quick check can save you from serious problems.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 7 of 10 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Aug 22, 2025.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Fertile Fields Teapills, straight from the product label.
| Brand | Plum Flower |
|---|---|
| Barcode (UPC) | 739934836552 |
| Net contents | 1.2 Ounce(s); 34 Gram(s); 200 Pill(s) |
| Market status | On market |
| Date entered into DSLD | Aug 22, 2025 |
| DSLD ID | 336461 |
| Product type | Botanical |
| Supplement form | Tablet Or Pill |
| Dietary claims / uses | All Other |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Fertile Fields Teapills by Plum Flower, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Proprietary Extract Blend | 1360 mg | -- |
| Angelica sinensis Root Extract | 0 NP | -- |
| Rehmannia glutinosa Root Extract | 0 NP | -- |
| Scutellaria baicalensis Root Extract | 0 NP | -- |
| Eucommia ulmoides Bark Extract | 0 NP | -- |
| Cyperus rotundus Rhizome Extract | 0 NP | -- |
| Ligusticum chuanxiong Rhizome Extract | 0 NP | -- |
| Dipsacus asper Root Extract | 0 NP | -- |
| Artemisia argyi Leaf Extract | 0 NP | -- |
| Equus asinus Gelatin extract | 0 NP | -- |
| Paeonia lactiflora Root Extract | 0 NP | -- |
Other ingredients: Microcrystalline Cellulose, Magnesium Silicate, Hydrated, Maltose, China Wax
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula
Fu Ke Zhong Zi Wan
FDA Statement of Identity
Herbal Supplement
Suggested/Recommended/Usage/Directions
Take 8 pills 3 times daily or as directed by your health care practitioner
Precautions
Keep out of reach of children
Seals/Symbols
Plum Flower Quality Guarantee Sourced Sustainably FDA Registered cGMP Compliant Made at a cGMP Certified Facility Lab Tested Quality Verified Species Verified
Foci Pharmaceutical 1929
Formulation
US owned & operated since 1969, Made in China in partnership with the award-winning Lanzhou Foci Pharmaceutical Co. Ltd.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Fertile Fields Teapills by Plum Flower label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Fertile Fields Teapills by Plum Flower
These are the 10 active ingredients this product is made of. Select any to open its full monograph.
Serving size8 Pill(s) Dosage formTablet Or Pill Servings per container25 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Proprietary Extract Blend
- › Angelica sinensis Root Extract
- › Rehmannia glutinosa Root Extract
- › Scutellaria baicalensis Root Extract
- › Eucommia ulmoides Bark Extract
- › Cyperus rotundus Rhizome Extract
- › Ligusticum chuanxiong Rhizome Extract
- › Dipsacus asper Root Extract
- › Artemisia argyi Leaf Extract
- › Equus asinus Gelatin extract
- › Paeonia lactiflora Root Extract
Other (inactive) ingredients: Microcrystalline Cellulose, Magnesium Silicate, Hydrated, Maltose, China Wax. These complete the product’s ingredient list but are not active constituents.
Fertile Fields Teapills by Plum Flower Drug Interactions
HelloPharmacist Interaction Report
Fertile Fields Teapills by Plum Flower contains multiple ingredients with documented interactions to medications.
The most serious concern is dong quai (Angelica sinensis), which carries a Major-severity risk with warfarin (a blood thinner)—case reports show it can increase bleeding risk by boosting warfarin's effects. Dong quai also interacts with blood thinners and antiplatelet drugs (Moderate severity) and estrogens like hormone replacement therapy (Moderate severity).
Read the full breakdown — every affected drug type, severity by severity
Baikal skullcap (Scutellaria baicalensis) has the widest interaction profile. It may lower blood pressure further if you're already on blood pressure medications (Moderate), increase levels of certain drugs your liver metabolizes—including some antidepressants and heart medications processed via CYP1A2 and CYP2C19 enzymes (Moderate)—and theoretically affect blood sugar control with diabetes medications (Moderate).
It also interacts with lithium mood stabilizers, antithyroid drugs, anticoagulants/antiplatelet drugs, and estrogens (all Moderate).
Rehmannia (Rehmannia glutinosa) may amplify the effects of blood pressure and diabetes medications (both Moderate severity). Peony (Paeonia lactiflora) has Moderate interactions with blood thinners, birth control pills, estrogen therapy, and certain psychiatric and seizure medications processed by the liver.
Several other ingredients—Eucommia ulmoides, Cyperus rotundus, Ligusticum chuanxiong, Dipsacus asper, and Artemisia argyi—we could not check; our monographs do not hold data for them.
Gelatine (Equus asinus) has no interactions documented in our data, though allergic reactions are possible. Altogether, these interactions span 1,239 individual medications.
Before you start this product, use the medication checker below with your exact prescriptions—especially blood thinners, blood pressure pills, diabetes medications, birth control, hormone therapy, psychiatric drugs, or seizure medications.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Fertile Fields Teapills?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Fertile Fields Teapills interact with 1,259 drugs. Click any drug to see the details.
5 of the 10 ingredients in Fertile Fields Teapills interact with drugs. Each result below shows which ingredient is responsible. Scutellaria baicalensis Root Extract Paeonia lactiflora Root Extract Rehmannia glutinosa Root Extract Cyperus rotundus Rhizome Extract Angelica sinensis Root Extract
WarfarinWarfarin
How Warfarin interacts with Fertile Fields Teapills — through 3 ingredients. Tap an ingredient for the detail:
Angelica Sinensis Root ExtractAnticoagulant/antiplatelet Drugs, Warfarin (coumadin) Major
Interaction Summary
Theoretically, dong quai may increase the risk of bleeding when used with anticoagulant or antiplatelet drugs; however, research is conflicting.
Read the full Angelica Sinensis Root Extract + Warfarin interactionScutellaria Baicalensis Root ExtractCytochrome P450 2c19 (cyp2c19) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, Baikal skullcap might increase levels of drugs metabolized by CYP2C19 enzymes.
Read the full Scutellaria Baicalensis Root Extract + Warfarin interactionPaeonia Lactiflora Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP1A2.
Read the full Paeonia Lactiflora Root Extract + Warfarin interactionWarfarin SodiumCoumadin, Panwarfin, Sofarin
How Warfarin Sodium interacts with Fertile Fields Teapills — through 3 ingredients. Tap an ingredient for the detail:
Angelica Sinensis Root ExtractAnticoagulant/antiplatelet Drugs, Warfarin (coumadin) Major
Interaction Summary
Theoretically, dong quai may increase the risk of bleeding when used with anticoagulant or antiplatelet drugs; however, research is conflicting.
Read the full Angelica Sinensis Root Extract + Warfarin Sodium interactionPaeonia Lactiflora Root ExtractAnticoagulant/antiplatelet Drugs, Cytochrome P450 1a2 (cyp1a2) Substrates +1 Moderate
Interaction Summary
Theoretically, combining peony with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Paeonia Lactiflora Root Extract + Warfarin Sodium interactionScutellaria Baicalensis Root ExtractAnticoagulant/antiplatelet Drugs, Cytochrome P450 2c19 (cyp2c19) Substrates +1 Moderate
Interaction Summary
Theoretically, Baikal skullcap might increase the risk of bleeding when used concomitantly with anticoagulant and antiplatelet drugs.
Read the full Scutellaria Baicalensis Root Extract + Warfarin Sodium interactionAdo-trastuzumab EmtansineKadcyla
How Ado-trastuzumab Emtansine interacts with Fertile Fields Teapills — through 1 ingredient. Tap an ingredient for the detail:
Paeonia Lactiflora Root ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP3A4.
Read the full Paeonia Lactiflora Root Extract + Ado-trastuzumab Emtansine interactionAbciximabReoPro
How Abciximab interacts with Fertile Fields Teapills — through 3 ingredients. Tap an ingredient for the detail:
Angelica Sinensis Root ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, dong quai may increase the risk of bleeding when used with anticoagulant or antiplatelet drugs; however, research is conflicting.
Read the full Angelica Sinensis Root Extract + Abciximab interactionPaeonia Lactiflora Root ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, combining peony with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Paeonia Lactiflora Root Extract + Abciximab interactionScutellaria Baicalensis Root ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, Baikal skullcap might increase the risk of bleeding when used concomitantly with anticoagulant and antiplatelet drugs.
Read the full Scutellaria Baicalensis Root Extract + Abciximab interactionAbemaciclibVerzenio
How Abemaciclib interacts with Fertile Fields Teapills — through 1 ingredient. Tap an ingredient for the detail:
Paeonia Lactiflora Root ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP3A4.
Read the full Paeonia Lactiflora Root Extract + Abemaciclib interactionAbiraterone
How Abiraterone interacts with Fertile Fields Teapills — through 1 ingredient. Tap an ingredient for the detail:
Paeonia Lactiflora Root ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP3A4.
Read the full Paeonia Lactiflora Root Extract + Abiraterone interactionAbiraterone AcetateYonsa, Zytiga
How Abiraterone Acetate interacts with Fertile Fields Teapills — through 1 ingredient. Tap an ingredient for the detail:
Paeonia Lactiflora Root ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP3A4.
Read the full Paeonia Lactiflora Root Extract + Abiraterone Acetate interactionAbrocitinibCibinqo
How Abrocitinib interacts with Fertile Fields Teapills — through 3 ingredients. Tap an ingredient for the detail:
Scutellaria Baicalensis Root ExtractAnticoagulant/antiplatelet Drugs, Cytochrome P450 2c19 (cyp2c19) Substrates Moderate
Interaction Summary
Theoretically, Baikal skullcap might increase the risk of bleeding when used concomitantly with anticoagulant and antiplatelet drugs.
Read the full Scutellaria Baicalensis Root Extract + Abrocitinib interactionAngelica Sinensis Root ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, dong quai may increase the risk of bleeding when used with anticoagulant or antiplatelet drugs; however, research is conflicting.
Read the full Angelica Sinensis Root Extract + Abrocitinib interactionPaeonia Lactiflora Root ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, combining peony with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Paeonia Lactiflora Root Extract + Abrocitinib interactionAcalabrutinibCalquence
How Acalabrutinib interacts with Fertile Fields Teapills — through 2 ingredients. Tap an ingredient for the detail:
Paeonia Lactiflora Root ExtractCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP3A4.
Read the full Paeonia Lactiflora Root Extract + Acalabrutinib interactionScutellaria Baicalensis Root ExtractP-glycoprotein Substrates Minor
Interaction Summary
Theoretically, Baikal skullcap might increase levels of drugs transported by P-glycoprotein.
Read the full Scutellaria Baicalensis Root Extract + Acalabrutinib interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Fertile Fields Teapills — through 2 ingredients. Tap an ingredient for the detail:
Scutellaria Baicalensis Root ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, concomitant use of Baikal skullcap with antidiabetes drugs might enhance blood glucose lowering effects.
Read the full Scutellaria Baicalensis Root Extract + Acarbose interactionRehmannia Glutinosa Root ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, rehmannia might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Rehmannia Glutinosa Root Extract + Acarbose interactionAcebutololRhotral, Sectral
How Acebutolol interacts with Fertile Fields Teapills — through 2 ingredients. Tap an ingredient for the detail:
Scutellaria Baicalensis Root ExtractAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, concomitant use of Baikal skullcap with antihypertensive drugs might have additive effects and increase the risk of hypotension.
Read the full Scutellaria Baicalensis Root Extract + Acebutolol interactionRehmannia Glutinosa Root ExtractAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, rehmannia might increase the risk of hypotension when taken with antihypertensive drugs.
Read the full Rehmannia Glutinosa Root Extract + Acebutolol interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Fertile Fields Teapills — through 3 ingredients. Tap an ingredient for the detail:
Angelica Sinensis Root ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, dong quai may increase the risk of bleeding when used with anticoagulant or antiplatelet drugs; however, research is conflicting.
Read the full Angelica Sinensis Root Extract + Acenocoumarol interactionPaeonia Lactiflora Root ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, combining peony with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
Read the full Paeonia Lactiflora Root Extract + Acenocoumarol interactionScutellaria Baicalensis Root ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, Baikal skullcap might increase the risk of bleeding when used concomitantly with anticoagulant and antiplatelet drugs.
Read the full Scutellaria Baicalensis Root Extract + Acenocoumarol interactionAcepromazineAtravet
How Acepromazine interacts with Fertile Fields Teapills — through 2 ingredients. Tap an ingredient for the detail:
Cyperus Rotundus Rhizome ExtractCns Depressants Moderate
Interaction Summary
Animal research suggests that taking adrue in combination with sodium thiopental or diazepam increases total sleep time up to four-fold compared to the effects of the drugs alone.
Read the full Cyperus Rotundus Rhizome Extract + Acepromazine interactionScutellaria Baicalensis Root ExtractCns Depressants Minor
Interaction Summary
Theoretically, Baikal skullcap might cause additive therapeutic and adverse effects when used concomitantly with drugs with sedative properties.
Read the full Scutellaria Baicalensis Root Extract + Acepromazine interactionAcetaminophenChildren's Tylenol, Children's Tylenol Meltaways, Tylenol, Tylenol Ex Strength
How Acetaminophen interacts with Fertile Fields Teapills — through 2 ingredients. Tap an ingredient for the detail:
Scutellaria Baicalensis Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, Baikal skullcap may increase levels of drugs metabolized by CYP1A2 enzymes.
Read the full Scutellaria Baicalensis Root Extract + Acetaminophen interactionPaeonia Lactiflora Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP1A2.
Read the full Paeonia Lactiflora Root Extract + Acetaminophen interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Fertile Fields Teapills — through 3 ingredients. Tap an ingredient for the detail:
Paeonia Lactiflora Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Anticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP1A2.
Read the full Paeonia Lactiflora Root Extract + Acetaminophen, Aspirin interactionScutellaria Baicalensis Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Anticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, Baikal skullcap may increase levels of drugs metabolized by CYP1A2 enzymes.
Read the full Scutellaria Baicalensis Root Extract + Acetaminophen, Aspirin interactionAngelica Sinensis Root ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, dong quai may increase the risk of bleeding when used with anticoagulant or antiplatelet drugs; however, research is conflicting.
Read the full Angelica Sinensis Root Extract + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Fertile Fields Teapills — through 3 ingredients. Tap an ingredient for the detail:
Scutellaria Baicalensis Root ExtractAnticoagulant/antiplatelet Drugs, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, Baikal skullcap might increase the risk of bleeding when used concomitantly with anticoagulant and antiplatelet drugs.
Read the full Scutellaria Baicalensis Root Extract + Acetaminophen, Aspirin, Caffeine interactionPaeonia Lactiflora Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP1A2.
Read the full Paeonia Lactiflora Root Extract + Acetaminophen, Aspirin, Caffeine interactionAngelica Sinensis Root ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, dong quai may increase the risk of bleeding when used with anticoagulant or antiplatelet drugs; however, research is conflicting.
Read the full Angelica Sinensis Root Extract + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Brompheniramine, PhenylpropanolamineDimetapp Cold and Flu
How Acetaminophen, Brompheniramine, Phenylpropanolamine interacts with Fertile Fields Teapills — through 2 ingredients. Tap an ingredient for the detail:
Paeonia Lactiflora Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP1A2.
Read the full Paeonia Lactiflora Root Extract + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionScutellaria Baicalensis Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, Baikal skullcap may increase levels of drugs metabolized by CYP1A2 enzymes.
Read the full Scutellaria Baicalensis Root Extract + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionAcetaminophen, ButalbitalAxocet, Bancap, Bucet, Butex Forte, Esgic CF, Orbivan CF +5 more
How Acetaminophen, Butalbital interacts with Fertile Fields Teapills — through 3 ingredients. Tap an ingredient for the detail:
Scutellaria Baicalensis Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, Baikal skullcap may increase levels of drugs metabolized by CYP1A2 enzymes.
Read the full Scutellaria Baicalensis Root Extract + Acetaminophen, Butalbital interactionPaeonia Lactiflora Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP1A2.
Read the full Paeonia Lactiflora Root Extract + Acetaminophen, Butalbital interactionCyperus Rotundus Rhizome ExtractBarbiturates Moderate
Interaction Summary
Animal research suggests that taking adrue in combination with sodium thiopental increases total sleep time three-fold compared to the effects of sodium thiopental alone.
Read the full Cyperus Rotundus Rhizome Extract + Acetaminophen, Butalbital interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with Fertile Fields Teapills — through 3 ingredients. Tap an ingredient for the detail:
Cyperus Rotundus Rhizome ExtractBarbiturates Moderate
Interaction Summary
Animal research suggests that taking adrue in combination with sodium thiopental increases total sleep time three-fold compared to the effects of sodium thiopental alone.
Read the full Cyperus Rotundus Rhizome Extract + Acetaminophen, Butalbital, Caffeine interactionScutellaria Baicalensis Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, Baikal skullcap may increase levels of drugs metabolized by CYP1A2 enzymes.
Read the full Scutellaria Baicalensis Root Extract + Acetaminophen, Butalbital, Caffeine interactionPaeonia Lactiflora Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP1A2.
Read the full Paeonia Lactiflora Root Extract + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with Fertile Fields Teapills — through 3 ingredients. Tap an ingredient for the detail:
Paeonia Lactiflora Root ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP3A4.
Read the full Paeonia Lactiflora Root Extract + Acetaminophen, Butalbital, Caffeine, Codeine interactionCyperus Rotundus Rhizome ExtractBarbiturates, Cns Depressants Moderate
Interaction Summary
Animal research suggests that taking adrue in combination with sodium thiopental increases total sleep time three-fold compared to the effects of sodium thiopental alone.
Read the full Cyperus Rotundus Rhizome Extract + Acetaminophen, Butalbital, Caffeine, Codeine interactionScutellaria Baicalensis Root ExtractCns Depressants, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, Baikal skullcap might cause additive therapeutic and adverse effects when used concomitantly with drugs with sedative properties.
Read the full Scutellaria Baicalensis Root Extract + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Butalbital, CodeineBancap w/ Codeine
How Acetaminophen, Butalbital, Codeine interacts with Fertile Fields Teapills — through 3 ingredients. Tap an ingredient for the detail:
Cyperus Rotundus Rhizome ExtractCns Depressants Moderate
Interaction Summary
Animal research suggests that taking adrue in combination with sodium thiopental or diazepam increases total sleep time up to four-fold compared to the effects of the drugs alone.
Read the full Cyperus Rotundus Rhizome Extract + Acetaminophen, Butalbital, Codeine interactionScutellaria Baicalensis Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cns Depressants Moderate
Interaction Summary
Theoretically, Baikal skullcap may increase levels of drugs metabolized by CYP1A2 enzymes.
Read the full Scutellaria Baicalensis Root Extract + Acetaminophen, Butalbital, Codeine interactionPaeonia Lactiflora Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP1A2.
Read the full Paeonia Lactiflora Root Extract + Acetaminophen, Butalbital, Codeine interactionAcetaminophen, Butalbital, Codeine PhosphatePhrenilin #3
How Acetaminophen, Butalbital, Codeine Phosphate interacts with Fertile Fields Teapills — through 3 ingredients. Tap an ingredient for the detail:
Paeonia Lactiflora Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP1A2.
Read the full Paeonia Lactiflora Root Extract + Acetaminophen, Butalbital, Codeine Phosphate interactionScutellaria Baicalensis Root ExtractCns Depressants, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, Baikal skullcap might cause additive therapeutic and adverse effects when used concomitantly with drugs with sedative properties.
Read the full Scutellaria Baicalensis Root Extract + Acetaminophen, Butalbital, Codeine Phosphate interactionCyperus Rotundus Rhizome ExtractCns Depressants Moderate
Interaction Summary
Animal research suggests that taking adrue in combination with sodium thiopental or diazepam increases total sleep time up to four-fold compared to the effects of the drugs alone.
Read the full Cyperus Rotundus Rhizome Extract + Acetaminophen, Butalbital, Codeine Phosphate interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with Fertile Fields Teapills — through 3 ingredients. Tap an ingredient for the detail:
Scutellaria Baicalensis Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cns Depressants Moderate
Interaction Summary
Theoretically, Baikal skullcap may increase levels of drugs metabolized by CYP1A2 enzymes.
Read the full Scutellaria Baicalensis Root Extract + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionPaeonia Lactiflora Root ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP3A4.
Read the full Paeonia Lactiflora Root Extract + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionCyperus Rotundus Rhizome ExtractCns Depressants Moderate
Interaction Summary
Animal research suggests that taking adrue in combination with sodium thiopental or diazepam increases total sleep time up to four-fold compared to the effects of the drugs alone.
Read the full Cyperus Rotundus Rhizome Extract + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with Fertile Fields Teapills — through 3 ingredients. Tap an ingredient for the detail:
Scutellaria Baicalensis Root ExtractCns Depressants, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, Baikal skullcap might cause additive therapeutic and adverse effects when used concomitantly with drugs with sedative properties.
Read the full Scutellaria Baicalensis Root Extract + Acetaminophen, Caffeine, Codeine interactionPaeonia Lactiflora Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP1A2.
Read the full Paeonia Lactiflora Root Extract + Acetaminophen, Caffeine, Codeine interactionCyperus Rotundus Rhizome ExtractCns Depressants Moderate
Interaction Summary
Animal research suggests that taking adrue in combination with sodium thiopental or diazepam increases total sleep time up to four-fold compared to the effects of the drugs alone.
Read the full Cyperus Rotundus Rhizome Extract + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with Fertile Fields Teapills — through 3 ingredients. Tap an ingredient for the detail:
Cyperus Rotundus Rhizome ExtractCns Depressants Moderate
Interaction Summary
Animal research suggests that taking adrue in combination with sodium thiopental or diazepam increases total sleep time up to four-fold compared to the effects of the drugs alone.
Read the full Cyperus Rotundus Rhizome Extract + Acetaminophen, Caffeine, Codeine, Salicylamide interactionScutellaria Baicalensis Root ExtractCns Depressants, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, Baikal skullcap might cause additive therapeutic and adverse effects when used concomitantly with drugs with sedative properties.
Read the full Scutellaria Baicalensis Root Extract + Acetaminophen, Caffeine, Codeine, Salicylamide interactionPaeonia Lactiflora Root ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP3A4.
Read the full Paeonia Lactiflora Root Extract + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with Fertile Fields Teapills — through 3 ingredients. Tap an ingredient for the detail:
Paeonia Lactiflora Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP1A2.
Read the full Paeonia Lactiflora Root Extract + Acetaminophen, Caffeine, Dihydrocodeine interactionCyperus Rotundus Rhizome ExtractCns Depressants Moderate
Interaction Summary
Animal research suggests that taking adrue in combination with sodium thiopental or diazepam increases total sleep time up to four-fold compared to the effects of the drugs alone.
Read the full Cyperus Rotundus Rhizome Extract + Acetaminophen, Caffeine, Dihydrocodeine interactionScutellaria Baicalensis Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cns Depressants Moderate
Interaction Summary
Theoretically, Baikal skullcap may increase levels of drugs metabolized by CYP1A2 enzymes.
Read the full Scutellaria Baicalensis Root Extract + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Caffeine, IsomethepteneMigralam
How Acetaminophen, Caffeine, Isometheptene interacts with Fertile Fields Teapills — through 2 ingredients. Tap an ingredient for the detail:
Paeonia Lactiflora Root ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP3A4.
Read the full Paeonia Lactiflora Root Extract + Acetaminophen, Caffeine, Isometheptene interactionScutellaria Baicalensis Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, Baikal skullcap may increase levels of drugs metabolized by CYP1A2 enzymes.
Read the full Scutellaria Baicalensis Root Extract + Acetaminophen, Caffeine, Isometheptene interactionAcetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with Fertile Fields Teapills — through 2 ingredients. Tap an ingredient for the detail:
Scutellaria Baicalensis Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, Baikal skullcap may increase levels of drugs metabolized by CYP1A2 enzymes.
Read the full Scutellaria Baicalensis Root Extract + Acetaminophen, Caffeine, Pyrilamine interactionPaeonia Lactiflora Root ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP3A4.
Read the full Paeonia Lactiflora Root Extract + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, Chlorpheniramine Maleate, Dextromethorphan HbrVicks Formula 44M Cough, Cold & Flu Relief
How Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interacts with Fertile Fields Teapills — through 2 ingredients. Tap an ingredient for the detail:
Paeonia Lactiflora Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP1A2.
Read the full Paeonia Lactiflora Root Extract + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionScutellaria Baicalensis Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates Moderate
Interaction Summary
Theoretically, Baikal skullcap may increase levels of drugs metabolized by CYP1A2 enzymes.
Read the full Scutellaria Baicalensis Root Extract + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionAcetaminophen, Chlorpheniramine, Codeine, PhenylephrineColrex
How Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interacts with Fertile Fields Teapills — through 3 ingredients. Tap an ingredient for the detail:
Paeonia Lactiflora Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP1A2.
Read the full Paeonia Lactiflora Root Extract + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionScutellaria Baicalensis Root ExtractCytochrome P450 1a2 (cyp1a2) Substrates, Cns Depressants Moderate
Interaction Summary
Theoretically, Baikal skullcap may increase levels of drugs metabolized by CYP1A2 enzymes.
Read the full Scutellaria Baicalensis Root Extract + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionCyperus Rotundus Rhizome ExtractCns Depressants Moderate
Interaction Summary
Animal research suggests that taking adrue in combination with sodium thiopental or diazepam increases total sleep time up to four-fold compared to the effects of the drugs alone.
Read the full Cyperus Rotundus Rhizome Extract + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Fertile Fields Teapills with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Scutellaria baicalensis Root Extract
Anticoagulant/Antiplatelet Drugs
Theoretically, Baikal skullcap might increase the risk of bleeding when used concomitantly with anticoagulant and antiplatelet drugs.
Preliminary clinical research suggests that taking capsules containing a combination of astragalus, goldthread, and Baikal skullcap daily for 4 weeks inhibits platelet aggregation; the effect seems to be similar to that of aspirin 50 mg daily. It is unclear if this effect is due to Baikal skullcap, other ingredients, or the combination.
Antidiabetes Drugs
Theoretically, concomitant use of Baikal skullcap with antidiabetes drugs might enhance blood glucose lowering effects.
Baicalein, a constituent of Baikal skullcap, has alpha-glucosidase inhibitory activity in vitro. Animal research also suggests that Baikal skullcap enhances the antidiabetic effects of metformin. However, in a small human study, taking Baikal skullcap extract did not enhance the antidiabetic effects of metformin, although it did modestly lower glucose levels during an oral glucose tolerance test (OGTT). Until more is known, use cautiously.
Antihypertensive Drugs
Theoretically, concomitant use of Baikal skullcap with antihypertensive drugs might have additive effects and increase the risk of hypotension.
Animal research suggests that baicalein, a constituent of Baikal skullcap, might lower blood pressure.
Antithyroid Drugs
Theoretically, concomitant use of Baikal skullcap and antithyroid drugs may result in additive activity and increase the risk of hypothyroidism.
In an animal hyperthyroid model, Baikal skullcap improved levels of triiodothyronine (T3), thyroxine (T4), and thyroid stimulating hormone (TSH). The clinical significance of this effect is unclear.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, Baikal skullcap may increase levels of drugs metabolized by CYP1A2 enzymes.
In vitro evidence suggests that constituents of Baikal skullcap inhibit the activity of CYP1A2. This effect has not been reported in humans.
Cytochrome P450 2C19 (Cyp2C19) Substrates
Theoretically, Baikal skullcap might increase levels of drugs metabolized by CYP2C19 enzymes.
In vitro evidence suggest that wogonin, a constituent of Baikal skullcap, modestly inhibits the activity of CYP2C19 enzymes. This effect has not been reported in humans.
Estrogens
Theoretically, concomitant use of large amounts of Baikal skullcap might interfere with hormone replacement therapy, due to competition for estrogen receptors.
In vitro evidence suggests that Baikal skullcap has estrogenic activity.
Lithium
Theoretically, Baikal skullcap might reduce lithium excretion and increase serum levels of lithium.
Baikal skullcap is thought to have diuretic properties, which may reduce lithium excretion. The dose of lithium might need to be decreased.
Alcohol (Ethanol)
Theoretically, Baikal skullcap might potentiate the sedative effects of alcohol.
In vitro and animal research suggests that Baikal skullcap binds to GABA-A receptors and causes sedation. Theoretically, Baikal skullcap might potentiate the sedative effects of alcohol. Preliminary clinical research has not identified clinically relevant sedation after use of Baikal skullcap; however, a thorough evaluation of safety outcomes has not been conducted.
Cns Depressants
Theoretically, Baikal skullcap might cause additive therapeutic and adverse effects when used concomitantly with drugs with sedative properties.
In vitro and animal research suggests that Baikal skullcap binds to GABA-A receptors and causes sedation. Theoretically, Baikal skullcap might cause additive therapeutic and adverse effects when used concomitantly with drugs with sedative properties. Preliminary clinical research has not identified clinically relevant sedation after use of Baikal skullcap; however, a thorough evaluation of safety outcomes has not been conducted.
Organic Anion-Transporting Polypeptide Substrates (Oatp)
Theoretically, Baikal skullcap might alter the levels and clinical effects of OATP substrates.
Some pharmacokinetic research shows that baicalin, a constituent of Baikal skullcap, can decrease plasma levels of rosuvastatin. The mechanism is thought to involve stimulation of the activity of the organic anion-transporting polypeptide 1B1 (OATP1B1), which transports rosuvastatin into the liver. This decreases plasma levels of the drug, but increases levels at the site of action in the liver. The degree to which rosuvastatin levels are affected depends on the OATP1B1 haplotype of the individual. Baikal skullcap might also affect other OATP1B1 substrates.
P-Glycoprotein Substrates
Theoretically, Baikal skullcap might increase levels of drugs transported by P-glycoprotein.
In vitro and animal research suggests that baicalein, oroxylin A, and wogonin, constituents of Baikal skullcap, can inhibit P-glycoprotein. This effect has not been reported in humans.
Paeonia lactiflora Root Extract
Anticoagulant/Antiplatelet Drugs
Theoretically, combining peony with anticoagulant or antiplatelet drugs might increase the risk of bleeding.
In vitro research suggests that peony might have antiplatelet, anticoagulant, and antithrombotic effects.
Clozapine (Clozaril)
Theoretically, peony might increase the levels and clinical effects of clozapine.
In vitro research shows that peony suppresses the metabolism of clozapine via weak-to-moderate inhibitory effects on cytochromes P450 (CYP) 1A2 and CYP3A4. This effect has not been reported in humans.
Contraceptive Drugs
Theoretically, peony might interfere with contraceptive drugs due to competition for estrogen receptors.
In vitro and animal research shows that peony extract has estrogenic activity. Concomitant use might also increase the risk for estrogen-related adverse effects.
Cytochrome P450 1A2 (Cyp1A2) Substrates
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP1A2.
In vitro research shows that peony suppresses the metabolism of clozapine via weak-to-moderate inhibitory effects on CYP1A2 and CYP3A4. This effect has not been reported in humans.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, use of peony may increase the levels and clinical effects of drugs metabolized by CYP3A4.
In vitro research shows that peony suppresses the metabolism of clozapine via weak-to-moderate inhibitory effects on CYP1A2 and CYP3A4. This effect has not been reported in humans.
Estrogens
Theoretically, concomitant use of large amounts of peony might interfere with hormone replacement therapy and/or increase the risk for estrogen-related adverse effects.
In vitro and animal research shows that peony extract has estrogenic activity. Theoretically, peony might compete for estrogen receptors and/or cause additive estrogenic effects.
Phenytoin (Dilantin)
Theoretically, peony might reduce the levels and clinical effects of phenytoin.
Animal research shows that taking peony root reduces levels of phenytoin. Some researchers suggest that peony root might affect cytochrome P450 (CYP) 2C9, which metabolizes phenytoin. However, preliminary research in humans shows that peony root does not alter levels of losartan (Cozaar), which is also metabolized by CYP2C9.
Rehmannia glutinosa Root Extract
Antidiabetes Drugs
Theoretically, rehmannia might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Animal research shows that rehmannia may have hypoglycemic effects.
Antihypertensive Drugs
Theoretically, rehmannia might increase the risk of hypotension when taken with antihypertensive drugs.
Animal research shows that rehmannia may have hypotensive effects. Laboratory research shows that formulations of dried and processed rehmannia root inhibit angiotensin-converting enzyme (ACE).
Cyperus rotundus Rhizome Extract
Barbiturates
Animal research suggests that taking adrue in combination with sodium thiopental increases total sleep time three-fold compared to the effects of sodium thiopental alone. Theoretically, concomitant use of adrue and barbiturates might increase the risk of drowsiness and motor reflex depression. Some barbiturates include amobarbital (Amytal), butabarbital (Butisol), mephobarbital (Mebaral), pentobarbital (Nembutal), phenobarbital (Luminal), secobarbital (Seconal), and others.
Benzodiazepines
Animal research suggests that taking adrue in combination with diazepam increases total sleep time four-fold compared to the effects of diazepam alone. Theoretically, concomitant use adrue and benzodiazepines might increase the risk of drowsiness and motor reflex depression. Some benzodiazepines include clonazepam (Klonopin), diazepam (Valium), lorazepam (Ativan), and others.
Cns Depressants
Animal research suggests that taking adrue in combination with sodium thiopental or diazepam increases total sleep time up to four-fold compared to the effects of the drugs alone. Theoretically, concomitant use of adrue with CNS depressants might cause additive sedation. Some CNS depressants include benzodiazepines, such as diazepam (Valium), alprazolam (Xanax), triazolam (Halcion), and estazolam (ProSom); barbiturates, such as mephobarbital (Mebaral), phenobarbital (Luminal Sodium), and pentobarbital sodium (Nembutal); zolpidem (Ambien); and others.
Angelica sinensis Root Extract
Warfarin (Coumadin)
Dong quai may increase the risk of bleeding when used with warfarin.
Case reports suggest that concomitant use of dong quai with warfarin can increase the anticoagulant effects of warfarin and increase the risk of bleeding. In one case, after 4 weeks of taking dong quai 565 mg once or twice daily, the international normalized ratio (INR) increased to 4.9. The INR normalized 4 weeks after discontinuation of dong quai.
Anticoagulant/Antiplatelet Drugs
Theoretically, dong quai may increase the risk of bleeding when used with anticoagulant or antiplatelet drugs; however, research is conflicting.
Animal studies suggest that dong quai has antithrombin activity and inhibits platelet aggregation due to its coumarin components. Additionally, some case reports in humans suggest that dong quai can increase the anticoagulant effects of warfarin. However, clinical research in healthy adults shows that taking 1 gram of dong quai root daily for 3 weeks does not significantly inhibit platelet aggregation or cause bleeding. Until more is known, use dong quai with caution in patients taking antiplatelet/anticoagulant drugs.
Estrogens
Theoretically, dong quai may reduce the effects of estrogens.
Dong quai has estrogenic effects. Theoretically, concomitant use of large amounts of dong quai might interfere with hormone replacement therapy due to competition for estrogen receptors.
Brand information
Manufacturer and brand details for Fertile Fields Teapills, from the product label.
Plum Flower
- Name
- Mayway Herbs
- City
- Oakland
- State
- CA
- Web Address
- plumflowerherbs.com
Fertile Fields Teapills by Plum Flower: Common Questions
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Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Fertile Fields Teapills’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Dong Quai
Interacts with 163 drugsDong Quai is a traditional Chinese herb often called "female ginseng" and is mostly used for menstrual and menopausal complaints. High-quality scientific evidence that it works for these use...
Read the full Dong Quai monograph → Herb & supplement monographRehmannia
Interacts with 258 drugsRehmannia is a root used for centuries in Traditional Chinese Medicine, often to 'tonify' the kidneys and support energy or blood health. Human evidence for most modern uses is limited, so i...
Read the full Rehmannia monograph → Herb & supplement monographBaikal Skullcap
Interacts with 946 drugsBaikal skullcap is a traditional Chinese herb (Huang Qin) used for inflammation, allergies, and infections, with active compounds like baicalin and baicalein studied mostly in the lab. Human...
Read the full Baikal Skullcap monograph → Herb & supplement monographAdrue
Interacts with 256 drugsAdrue (Cyperus articulatus) is a sedge whose rhizome has long been used in traditional medicine for nausea and other stomach complaints, and as a mild calming agent. Solid human studies are...
Read the full Adrue monograph → Herb & supplement monographMugwort
Mugwort is a traditional herb used for digestion, menstrual issues, and sleep, but there is very little high-quality human research to confirm these uses. It is closely related to ragweed an...
Read the full Mugwort monograph → Herb & supplement monographGelatin
Gelatin is a protein made from animal collagen, used as a food, a capsule ingredient, and a supplement for joint, skin, and bone health. For most health uses, the evidence is limited or mixe...
Read the full Gelatin monograph → Herb & supplement monographPeony
Interacts with 811 drugsPeony root is a traditional Chinese medicine herb often used for menstrual problems, cramps, and inflammation, frequently as part of combination formulas. Human evidence for most uses is lim...
Read the full Peony monograph →Sources & How We Checked
Fertile Fields Teapills's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 90 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Dong Quai 19 references
- Hirata JD, Swiersz LM, Zell B, et al. Does dong quai have estrogenic effects in postmenopausal women? A double-blind, placebo-controlled trial. Fertil Steril 1997;68:981-6. PubMed
- Page RL II, Lawrence JD. Potentiation of warfarin by dong quai. Pharmacotherapy 1999;19:870-6. PubMed
- Heck AM, DeWitt BA, Lukes AL. Potential interactions between alternative therapies and warfarin. Am J Health Syst Pharm 2000;57:1221-7. DOI
- Eagon PK, Elm MS, Hunter DS, et al. Medicinal herbs: modulation of estrogen action. Era of Hope Mtg, Dept Defense; Breast Cancer Res Prog, Atlanta, GA 2000;Jun 8-11.
- Dr. Duke's Phytochemical and Ethnobotanical Databases. Available at: http://www.ars-grin.gov/duke/.
- Amato P, Christophe S, Mellon PL. Estrogenic activity of herbs commonly used as remedies for menopausal symptoms. Menopause 2002;9:145-50. PubMed
- Shi M, Chang L, He G. [Stimulating action of Carthamus tinctorius L., Angelica sinensis (Oliv.) Diels and Leonurus sibiricus L. on the uterus]. Zhongguo Zhong Yao Za Zhi 1995;20:173-5, 192.
- Hoult JR, Paya M. Pharmacological and biochemical actions of simple coumarins: natural products with therapeutic potential. Gen Pharmacol 1996;27:713-22.. PubMed
- Cheong JL, Bucknall R. Retinal vein thrombosis associated with a herbal phytoestrogen preparation in a susceptible patient. Postgrad Med J 2005;81:266-7.. PubMed
- Chang CJ, Chiu JH, Tseng LM, et al. Modulation of HER2 expression by ferulic acid on human breast cancer MCF7 cells. Eur J Clin Invest 2006;36:588-96. PubMed
- Chuang CH, Doyle P, Wang JD, et al. Herbal medicines used during the first trimester and major congenital malformations: an analysis of data from a pregnancy cohort study. Drug Saf 2006;29:537-48. PubMed
- Lau CBS, Ho TCY, Chan TWL, Kim SCF. Use of dong quai (Angelica sinensis) to treat peri- and postmenopausal symptoms in women with breast cancer: is it appropriate? Menopause 2005;12:734-40.
- Ellis GR, Stephens MR. Untitled (photograph and a brief case report). BMJ 1999;319:650.
- Nambiar, S., Schwartz, R. H., and Constantino, A. Hypertension in mother and baby linked to ingestion of Chinese herbal medicine. West J Med 1999;171(3):152.
- Lee, S. K., Cho, H. K., Cho, S. H., Kim, S. S., Nahm, D. H., and Park, H. S. Occupational asthma and rhinitis caused by multiple herbal agents in a pharmacist. Ann.Allergy Asthma Immunol. 2001;86(4):469-474. PubMed
- Xu, J. and Li, G. [Observation on short-term effects of Angelica injection on chronic obstructive pulmonary disease patients with pulmonary hypertension]. Zhongguo Zhong Xi Yi Jie He Za Zhi 2000;20(3):187-189.
- Scott, G. N. and Elmer, G. W. Update on natural product--drug interactions. Am J Health Syst.Pharm 2-15-2002;59(4):339-347. PubMed
- Circosta, C., Pasquale, R. D., Palumbo, D. R., Samperi, S., and Occhiuto, F. Estrogenic activity of standardized extract of Angelica sinensis. Phytother.Res. 2006;20(8):665-669.
- Fung FY, Wong WH, Ang SK, et al. A randomized, double-blind, placebo- controlled study on the anti-haemostatic effects of Curcuma longa, Angelica sinensis and Panax ginseng. Phytomedicine. 2017;32:88-96. PubMed
Rehmannia 3 references
- Zhang R, Zhou J, Jia Z, et al. Hypoglycemic effect of Rehmannia glutinosa oligosaccharide in hyperglycemic and alloxan-induced diabetic rats and its mechanism. J Ethnopharmacol 2004;90:39-43. PubMed
- Zhang RX, Li MX, Jia ZP. Rehmannia glutinosa: review of botany, chemistry and pharmacology. J Ethnopharmacol 2008;117(2):199-214. PubMed
- Chao CH, Hsu JL, Chen MF, et al. Anti-hypertensive effects of Radix Rehmanniae and its active ingredients. Nat Prod Res. 2020;34(11):1547-1552.
Baikal Skullcap 34 references
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