Interactions on record — worth a quick check against your medications. Based on 3 of 5 ingredients. Check your meds →
Dietary supplement

Wu Ling Teapills Wu Ling Wan Ingredients & Drug Interactions

by Plum Flower

Tablet Or Pill Category: Botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Wu Ling Teapills Wu Ling Wan is a dietary supplement by Plum Flower with 5 active ingredients. Its ingredients are commonly taken for fluid retention and swelling, digestive complaints, sleep and calming support.Based on those ingredients, 1,267 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Atractylodes macrocephala Rhizome Extract, Cinnamomum cassia Twig Extract, Poria cocos Sclerotium Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Wu Ling Teapills Wu Ling Wan by Plum Flower

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 5 active ingredients.
  • “Proprietary Extract Blend” is a proprietary blend — the label gives one combined amount (1,360 mg) without saying how much of each component you get.

Wu Ling Teapills contains five active ingredients delivered as a proprietary extract blend. The main components are poria mushroom sclerotium extract (which appears twice in the formula), cassia cinnamon twig extract, atractylodes rhizome extract, and alisma orientale rhizome extract.

The formula also includes inactive ingredients — dextrin, hydrated magnesium silicate, activated carbon, and china wax — which serve as binders, flow agents, and tablet coating.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

The label doesn't state a purpose we can grade — see each ingredient's own graded uses on its monograph instead.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The effectiveness evidence for Wu Ling Teapills is not established in the data we hold. For poria mushroom and atractylodes, the conditions studied include diarrhea, diabetes, dementia, and fatigue, but all were rated insufficient reliable evidence to rate.

Cassia cinnamon has been studied for diabetes, dyslipidemia, and the common cold with the same outcome — insufficient evidence. We do not have effectiveness data on file for alisma orientale.

The evidence, ingredient by ingredient Poria Mushroom Cassia Cinnamon Atractylodes

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Poria mushroom extract and atractylodes are generally well tolerated in traditional use, but human safety data are limited. Cassia cinnamon at food amounts is likely safe, but at supplement doses — especially high-dose or long-term use — there's concern about liver stress from its coumarin content.

In clinical trials, one person taking cassia cinnamon 1 gram daily reported a rash, and one reported a low blood sugar seizure (though causation wasn't clear). Rare allergic reactions to poria mushroom have included allergic rhinitis and asthma.

Atractylodes may cause allergic reactions, dry mouth, or nausea. During pregnancy, poria mushroom and atractylodes carry safety data advising against use.

Cassia cinnamon at food amounts is likely safe, but concentrated supplement doses should be avoided in pregnancy. For breastfeeding, poria mushroom and atractylodes have no reliable safety data and should be avoided; cassia cinnamon at food amounts is likely fine, but high-dose supplements lack data.

We hold no pregnancy or breastfeeding information for alisma orientale.

Side effects, ingredient by ingredient Poria Mushroom Cassia Cinnamon Atractylodes

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 3 of the 3 matched ingredients can interact with medications — Poria Mushroom, Cassia Cinnamon, Atractylodes.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications.
  • For scale: 1,268 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking Wu Ling Teapills, check whether you're on sedatives or depressants that slow the central nervous system (Moderate risk), diabetes medications (Moderate), blood thinners or antiplatelet drugs (Moderate), or any drug processed through the liver — especially hexobarbital or medications affected by CYP1A2 and CYP3A4 enzymes (Minor risk). If you take any of these, run them through the medication checker on this page.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Wu Ling Teapills is a traditional Chinese formula with limited human safety and effectiveness data. If you take sedatives, diabetes medications, blood thinners, or any prescription drug, check your exact medications against the tool on this page before you start.

Pregnant or breastfeeding? Talk to your pharmacist first — several ingredients aren't recommended in these situations.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 4 of 5 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jun 20, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Wu Ling Teapills Wu Ling Wan, straight from the product label.

Brand Plum Flower
Barcode (UPC) 739934833308
Net contents 1.2 Ounce(s); 34 Gram(s); 200 Pill(s)
Market status On market
Date entered into DSLD Jun 20, 2024
DSLD ID 310595
Product type Botanical
Supplement form Tablet Or Pill
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Wu Ling Teapills Wu Ling Wan by Plum Flower, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
8 Pill(s)
Maximum serving Sizes:
8 Pill(s)
Servings per container
25
UPC/BARCODE
739934833308
IngredientAmount% DV
Proprietary Extract Blend1360 mg--
Poria cocos Sclerotium Extract0 NP--
Cinnamomum cassia Twig Extract0 NP--
Alisma orientale Rhizome Extract0 NP--
Atractylodes macrocephala Rhizome Extract0 NP--
Polyporus umbellatus Sclerotium Extract0 NP--

Other ingredients: Dextrin, Magnesium Silicate, Hydrated, Carbon, Activated, China Wax

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity

Herbal Supplement

Precautions

Processed with wheat bran

Caution during pregnancy

Keep out of reach of children

Suggested/Recommended/Usage/Directions

Take 8 pills 3 times daily or as directed by your health care practitioner

Formulation

US owned & operated since 1969. Made in China in partnership with the award-winning Lanzhou Foci Pharmaceutical Co. Ltd.

No pharmaceuticals or dyes Unsulfured, preservative-free herbs when available Microbial and heavy metal tested

Scientifically authenticated herbs

Produced at a Good Manufacturing Practices (GMP) certified factory

General Statements

Plum Flower Quality Guarantee

Foci Pharmaceutical 1929

See for yourself

Wu Ling Teapills Wu Ling Wan by Plum Flower label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Wu Ling Teapills Wu Ling Wan by Plum Flower

These are the 5 active ingredients this product is made of. Select any to open its full monograph.

Serving size8 Pill(s) Dosage formTablet Or Pill Servings per container25 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Proprietary Extract Blend

1360 mg per serving

Other (inactive) ingredients: Dextrin, Magnesium Silicate, Hydrated, Carbon, Activated, China Wax. These complete the product’s ingredient list but are not active constituents.

Interaction report

Wu Ling Teapills Wu Ling Wan by Plum Flower Drug Interactions

Want to check YOUR meds against Wu Ling Teapills Wu Ling Wan?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
1,267Drugs
897 Moderate 370 Minor

Each ingredient & the kinds of drugs it affects

For each ingredient in Wu Ling Teapills Wu Ling Wan with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Atractylodes macrocephala Rhizome Extract5 drug types · 801 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, atractylodes might increase the risk of bleeding when used concomitantly with anticoagulant and antiplatelet drugs.
Laboratory research suggests that atractylenolides II and III, constituents of atractylodes, reduce platelet activation. So far, this has not been shown in humans.

Likelihood Possible Evidence D
Aromatase Inhibitors

Theoretically, atractylodes may have an additive effect when used with other aromatase inhibitors.
Laboratory research suggests that atractylodes and its constituents exhibit aromatase inhibitor effects.

Likelihood Possible Evidence D
Hexobarbital

Theoretically, taking atractylodes may prolong the therapeutic and adverse effects of hexobarbital.
In animals, atractylodes has been shown to prolong the effects of hexobarbital. These effects have not been shown in humans.

Likelihood Possible Evidence D
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, atractylodes might decrease the levels of CYP1A2 substrates.
In animals, atractylodes administered at high doses has been shown to induce CYP1A2 activity. This effect has not been shown in humans.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, atractylodes might increase the levels of CYP3A4 substrates.
In animals, atractylodes administered at high doses has been shown to inhibit CYP3A1 activity, which is a homolog to the human CYP3A4 enzyme. This effect has not been shown in humans.

Likelihood Possible Evidence D

Cinnamomum cassia Twig Extract2 drug types · 442 drugs

Antidiabetes Drugs

Theoretically, cassia cinnamon may have additive effects with antidiabetes drugs.
Cassia cinnamon may lower blood glucose levels, and have additive effects in patients treated with antidiabetic agents. Dose adjustments to diabetes medications might be necessary.

Likelihood Possible Evidence B
Hepatotoxic Drugs

Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
There is some concern that ingesting large amounts of cassia cinnamon for an extended duration might cause hepatotoxicity in some people. Cassia cinnamon contains coumarin, which can cause hepatotoxicity in animal models. In humans, very high doses of coumarin from 50-7000 mg/day can result in hepatotoxicity that resolves when coumarin use is discontinued. Lower amounts might also cause liver problems in sensitive people, such as those with liver disease or those taking potentially hepatotoxic agents.

Likelihood Possible Evidence D

Poria cocos Sclerotium Extract3 drug types · 417 drugs

Anticholinergic Drugs

Theoretically, poria mushroom might decrease the clinical effects of anticholinergic drugs.
In animal research, poria mushroom essential oil reduces acetylcholinesterase activity. This interaction has not been shown in humans.

Likelihood Possible Evidence D
Cholinergic Drugs

Theoretically, poria mushroom might have additive effects when used with cholinergic drugs.
In animal research, poria mushroom essential oil reduces acetylcholinesterase activity. This interaction has not been shown in humans.

Likelihood Possible Evidence D
Cns Depressants

Theoretically, taking poria mushroom extract may enhance the therapeutic and adverse effects of sedatives.
Animal research shows that poria mushroom extract has sedative properties. This interaction has not been shown in humans.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Wu Ling Teapills Wu Ling Wan, from the product label.

Plum Flower

Name
Mayway Herbs
City
Oakland
State
CA
Web Address
www.plumflowerherbs.com
Pharmacist Counseling Corner

Wu Ling Teapills Wu Ling Wan by Plum Flower: Common Questions

Does Wu Ling Teapills Wu Ling Wan by Plum Flower interact with any medications?
Yes. Based on its ingredients, Wu Ling Teapills Wu Ling Wan has a known interaction with 1,267 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Wu Ling Teapills Wu Ling Wan contains 5 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take Wu Ling Teapills if I'm pregnant or breastfeeding?
Not without talking to your doctor or pharmacist first. Poria mushroom and atractylodes are best avoided during both pregnancy and breastfeeding — the safety data advise against them. Cassia cinnamon at regular food amounts is likely okay, but concentrated supplement doses lack safety data in pregnancy. For breastfeeding, we don't have reliable information on cassia at supplement doses either.
What are the side effects of Wu Ling Teapills?
Adverse effects data are limited. Poria mushroom can rarely cause allergic reactions including allergic rhinitis or asthma. Atractylodes may cause allergic reactions, dry mouth, or nausea — most adverse effects come from an isolated constituent that can also cause bad taste. Cassia cinnamon caused a rash in one trial participant taking 1 gram daily, and contact dermatitis has been reported in people allergic to cinnamic alcohol.
What is poria mushroom used for in this formula?
Poria mushroom has been studied for diarrhea, diabetes, dementia, fatigue, and cancer in traditional use, but we don't have enough reliable evidence to rate how well it works for any of these.
Does this product work for diabetes?
All three ingredients studied for diabetes — poria mushroom, cassia cinnamon, and atractylodes — had insufficient reliable evidence to rate in the data we hold. Cassia cinnamon may lower blood sugar, but effectiveness isn't established.
Can Wu Ling Teapills interact with my blood pressure medications?
We don't have documented interactions between these ingredients and blood pressure medications specifically. That said, check your exact medications in the tool on this page — your doctor or pharmacist can give you personalized advice based on what you're taking.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Wu Ling Teapills Wu Ling Wan is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Wu Ling Teapills Wu Ling Wan label
Sources

Sources & How We Checked

Wu Ling Teapills Wu Ling Wan's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 29 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Poria Mushroom 3 references
  1. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  2. Kim H, Park I, Park K, Park S, Kim YI, Park BG. The positive effects of Poria cocos extract on quality of sleep in insomnia rat models. Int J Environ Res Public Health 2022;19(11):6629. PubMed
  3. Lv Q, Di X, Bian B, Li K, Guo J. Neuroprotective effects of Poria cocos (Agaricomycetes) essential oil on Aß1-40-induced learning and memory deficit in rats. Int J Med Mushrooms 2022;24(10):73-82.

See these in context on the Poria Mushroom monograph →

Cassia Cinnamon 20 references
  1. Electronic Code of Federal Regulations. Title 21. Part 182 -- Substances Generally Recognized As Safe. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182
  2. Khan A, Safdar M, Ali Khan M, et al. Cinnamon improves glucose and lipids of people with type 2 diabetes. Diabetes Care 2003;26:3215-8. PubMed
  3. De Benito V, Alzaga R. Occupational allergic contact dermatitis from cassia (Chinese cinnamon) as a flavouring agent in coffee. Contact Dermatitis 1999;40:165. PubMed
  4. Drake TE, Maibach HI. Allergic contact dermatitis and stomatitis caused by a cinnamic aldehyde-flavored toothpaste. Arch Dermatol 1976;112:202-3.
  5. Press release. Cinnamon capsules to reduce blood sugar are medicinal products! Efficacy has not been scientifically proven - some products contain high levels of coumarin. Federal Institute of Risk Assessment (BfM), Germany, November 11, 2006. Available a
  6. Felter SP, Vassallo JD, Carlton BD, Daston GP. A safety assessment of coumarin taking into account species-specificity of toxicokinetics. Food Chem Toxicol 2006;44:462-75. PubMed
  7. Crawford P. Effectiveness of cinnamon for lowering hemoglobin A1C in patients with type 2 diabetes: a randomized, controlled trial. J Am Board Fam Med 2009;22:507-12. PubMed
  8. Akilen, R., Tsiami, A., Devendra, D., and Robinson, N. Glycated haemoglobin and blood pressure-lowering effect of cinnamon in multi-ethnic Type 2 diabetic patients in the UK: a randomized, placebo-controlled, double-blind clinical trial. Diabet.Med. 2010; PubMed
  9. Lu T, Sheng H Wu J Cheng Y Zhu J Chen Y. Cinnamon extract improves fasting blood glucose and glycosylated hemoglobin level in Chinese patients with type 2 diabetes. Nutr Res. 2012;32(6):408-412. PubMed
  10. Choi, J., Lee, K. T., Ka, H., Jung, W. T., Jung, H. J., and Park, H. J. Constituents of the essential oil of the Cinnamomum cassia stem bark and the biological properties. Arch Pharm Res 2001;24(5):418-423.
  11. Altschuler JA, Casella SJ, MacKenzie TA, Curtis KM. The effect of cinnamon on A1C among adolescents with type 1 diabetes. Diabetes Care 2007;30(4):813-6. PubMed
  12. Stoecker BR, Zhan Z, Luo R, et al. Cinnamon extract lowers blood glucose in hyperglycemic subjects. FASEB J. 2010;22:722.1 (Abstract only). DOI
  13. Admani S, Hill H, Jacob SE. Cinnamon Sugar Scrub Dermatitis: "Natural" Is Not Always Best. Pediatr Dermatol. 2017;34(1):e42-e43. PubMed
  14. Isaac-Renton M, Li MK, Parsons LM. Cinnamon spice and everything not nice: many features of intraoral allergy to cinnamic aldehyde. Dermatitis. 2015;26(3):116-21. PubMed
  15. Vandersall A, Katta R. Eyelid dermatitis as a manifestation of systemic contact dermatitis to cinnamon. Dermatitis. 2015 Jul-Aug;26(4):189. PubMed
  16. Wickenberg J, Lindstedt S, Nilsson J, Hlebowicz J. Cassia cinnamon does not change the insulin sensitivity or the liver enzymes in subjects with impaired glucose tolerance. Nutr J 2014 Sep 24;13:96. PubMed
  17. Brancheau D, Patel B, Zughaib M. Do cinnamon supplements cause acute hepatitis? Am J Case Rep 2015;16:250-4. PubMed
  18. Shekarchizadeh-Esfahani P, Heydarpour F, Izadi F, Jalili C. The effect of cinnamon supplementation on liver enzymes in adults: A systematic review and meta-analysis of randomized controlled trials. Complement Ther Med 2021;58:102699. PubMed
  19. Bernaola J, Valverde-Monge M, Otal-Buesa M, Cullen D, Heras-Mendaza F. Cinnamon allergic contact cheilitis. Contact Dermatitis 2023;88(5):418-419. PubMed
  20. Patel K, Howard M, Tate B. Cheilitis caused by allergic contact dermatitis to cinnamon in chai tea: A case report. Contact Dermatitis 2023;88(3):239-240. PubMed

See these in context on the Cassia Cinnamon monograph →

Atractylodes 6 references
  1. Liu Y, Jia Z, Dong L, et al. A randomized pilot study of atractylenolide I on gastric cancer cachexia patients. Evid Based Complement Alternat Med 2008;5:337-44. PubMed
  2. Chen Y, Yang W, Guo L, Wu X, Zhang T, Liu J, Zhang J. Atractylodes lactone compounds inhibit platelet activation. Platelets. 2017 Mar;28(2):194-202. PubMed
  3. Jiang H, Shi J, Li Y. Screening for compounds with aromatase inhibiting activities from Atractylodes macrocephala Koidz. Molecules. 2011 Apr 14;16(4):3146-51. PubMed
  4. Koonrungsesomboon N, Na-Bangchang K, Karbwang J. Therapeutic potential and pharmacological activities of Atractylodes lancea (Thunb.) DC. Asian Pac J Trop Med. 2014 Jun;7(6):421-8. PubMed
  5. Li L, Tang LY, Man GC, Yeung BH, Lau CB, Leung PC, Wang CC. Potential reproductive toxicity of Largehead Atractylodes Rhizome, the most commonly used Chinese medicine for threatened miscarriage. Hum Reprod. 2011 Dec;26(12):3280-8. PubMed
  6. Muhamad N, Plengsuriyakarn T, Na-Bangchang K. Atractylodes lancea for cholangiocarcinoma: Modulatory effects on CYP1A2 and CYP3A1 and pharmacokinetics in rats and biodistribution in mice. PLoS One 2022;17(11):e0277614. PubMed

See these in context on the Atractylodes monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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