Fibermucil Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Fibermucil against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Fibermucil is a dietary supplement by ProCaps Laboratories with 3 active ingredients. Its ingredients are commonly taken for constipation, diarrhea, high cholesterol.Based on those ingredients, 2,083 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Dietary Fiber, Lactobacillus sporogenes. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Fibermucil by ProCaps Laboratories
Ask about any prescription or over-the-counter medication and we check it for interactions with Fibermucil by ProCaps Laboratories — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Fibermucil by ProCaps Laboratories
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Partial disclosure
Fibermucil contains four active ingredients: psyllium powder, soluble fiber, insoluble fiber, and Lactobacillus sporogenes (a probiotic strain). Together they're designed to support digestive health through both fiber and beneficial bacteria.
The product also contains a gelatin capsule as an inactive ingredient.
Does it work?
Strong evidence
The probiotic Lactobacillus sporogenes (Bacillus coagulans) is possibly effective for constipation and irritable bowel syndrome (IBS) — meaning there's some evidence it may help, but it's not definitive. For antibiotic-associated diarrhea, athletic performance, cancer prevention, and nonalcoholic fatty liver disease, the evidence isn't established well enough to rate it.
We don't have effectiveness data on file for the fiber components (psyllium, soluble, and insoluble fiber) in this product.
How safe is it?
Well-documented data
Lactobacillus sporogenes is generally well tolerated in healthy adults, though evidence and product quality vary between brands. There isn't enough reliable safety data overall — talk to your doctor before using this product.
One rare concern: since the probiotic contains live organisms, there's a small risk of infection (bacteremia or sepsis) in people with central venous catheters, severe illness, or weakened immune systems, including very premature infants. In relatively healthy people with normal immune function and no indwelling catheters, this risk appears to be very low.
Meds to double-check
Moderate interaction found
Antibiotics are the main medication type to check — taking them at the same time as this product may reduce the probiotic's effectiveness. Separate doses by a few hours and confirm the timing with your pharmacist.
The bottom line
Scorecard at a glancePartially disclosed formula with clinical evidence supporting its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
Fibermucil might help with constipation or IBS symptoms, and it's generally well tolerated. If you take antibiotics, space them out from this supplement so the medication doesn't kill off the probiotic.
Talk to your pharmacist or doctor before starting, especially if you're seriously ill, have a weakened immune system, or have any catheters in place.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 2 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Nov 22, 2022.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Fibermucil, straight from the product label.
| Brand | ProCaps Laboratories |
|---|---|
| Barcode (UPC) | 392943 |
| Net contents | 360 Easy-To-Swallow Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Nov 22, 2022 |
| DSLD ID | 275256 |
| Product type | Other Combinations |
| Supplement form | Capsule |
| Dietary claims / uses | Nutrient, All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Fibermucil by ProCaps Laboratories, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Calories | 0 Calorie(s) | -- |
| Total Carbohydrates | 1 Gram(s) | 1% |
| Psyllium powder | 1.3 Gram(s) | -- |
| Dietary Fiber | 1.1 Gram(s) | 4% |
| Soluble Fiber | 0.9 Gram(s) | -- |
| Insoluble Fiber | 0.2 Gram(s) | -- |
| Lactobacillus sporogenes | 0 NP | -- |
Other ingredients: Gelatin Capsule
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Suggested use Consume one or more capsules daily with each meal or as directed by your physician. As with any dietary supplement, this natural product is most effective as part of a healthy diet and active lifestyle.
General Statements
For questions about the use of this product call 800.332.7799.
For over 40 years unsurpassed purity, quality and efficacy
100% solar production Zero carbon footprint Andrew Lessman, founder
100% solar
Fibermucil provides a gentle, but powerful source of mother nature's best source of dietary fiber without any of the undesirable ingredients or unpleasant problems associated with typical fiber products.
Precautions
Notice All fiber products should be taken with ample liquid. Consuming any fiber product without adequate fluid may cause choking. Do not use fiber product if you have difficulty swallowing. If you feel abdominal discomfort when using this product, discontinue use and consult a physician. Initially, when using this product, evacuations may not occur until the second day, hence you may experience a temporary feeling of fullness.
Ingested psyllium husk may cause rare allergic reactions.
If you are taking prescription medicines, it is best to consume them an hour or more before or after this product.
Formula
Naturally gentle pure psyllium fiber Natural psyllium fiber in small capsules Rich in water-soluble and bulk fiber plus lactobacillus friendly flora
Andrew Lessman's Fibermucil is all-natural, 100% pure, encapsulated psyllium husk powder from the high-fiber plantago ovata plant. It contains no additives and provides an unparalleled, natural source of fiber without unpleasant problems.
We also add lactobacillus sporogenes to enhance the balance of friendly flora in the GI microbiome.
FDA Statement of Identity
Dietary Supplement
Formulation
It contains no additives of any kind and provides an unparalleled natural source of fiber without unpleasant problems.
Fibermucil is a gentle, ultra-fine powder in small, easy-to-swallow capsules.
Unlike typical fiber products and drinks there are no added colors, flavors, calories or synthetic ingredients.
Dietary fiber provides a myriad of health benefits and is often considered the most overlooked ingredient in the american diet. Not only does fiber support weightloss by providing feelings of fullness, but the unique soluble fiber in fibermucil can also help to support healthy blood cholesterol levels. It is well established that daily consumption of soluble fiber, such as that found in fibermucil, is an easy means of supporting heart health. The natural fiber in this product acts as a gentle "sponge" and "broom" to naturally cleanse the digestive tract, removing undigested food, debris and other digestive by-products. Fiber is required for regularity and improving gastrointestinal (GI) transit time helping to remove undesirable digestive byproducts from the body. Decades of clinical science consistently demonstrate the short and long-term health benefits of a high-fiber diet. It is well established that adequate fiber intake is vital for the optimal health benefits of a high-fiber diet. It is well established that adequate fiber intake is vital for the optimal health and function of not just the digestive system, but all body systems.
Contains no common allergens Contains no milk, soy, yeast, wheat, gluten, sodium, salt, sugar, fat, cholesterol, color, preservative, common allergens, genetically modified (GMO) ingredients, or manufacturing additives.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Fibermucil by ProCaps Laboratories label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Fibermucil by ProCaps Laboratories
These are the 3 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Capsule(s) Dosage formCapsule Servings per container180 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Psyllium powder
Dietary Fiber
Interacts with2,025 drugs
Black psyllium is a soluble-fiber supplement made from the seeds of a Plantago plant, used mostly to ease constipation and support digestive health. I...
Dietary Fiber monograph & interactions- › Soluble Fiber
- › Insoluble Fiber
Lactobacillus sporogenes
Interacts with182 drugs
Bacillus coagulans is a spore-forming probiotic that survives stomach acid well and may help with some digestive problems such as IBS, constipation, a...
Lactobacillus sporogenes monograph & interactionsOther (inactive) ingredients: Gelatin Capsule. These complete the product’s ingredient list but are not active constituents.
Fibermucil by ProCaps Laboratories Drug Interactions
HelloPharmacist Interaction Report
Fibermucil by ProCaps Laboratories contains four ingredients, and we could only check one of them for interactions with medications.
Lactobacillus sporogenes (linked to Bacillus coagulans) has a Moderate interaction with antibiotics — taking them together might reduce how well the probiotic works, because antibiotics can kill off the live organisms in the product. You'll want to space out your antibiotic doses and this supplement by a few hours.
Read the full breakdown — every affected drug type, severity by severity
We couldn't check the interaction data for psyllium powder, soluble fiber, or insoluble fiber — we don't hold monographs for those ingredients. That doesn't mean they don't interact with anything; it just means the data isn't on file for us to review.
Altogether, these interactions span 182 individual medications.
Before you start Fibermucil, run your exact medications through the search tool below. If you take an antibiotic, ask us or your doctor how to time it safely with this supplement.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Fibermucil?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Fibermucil interact with 2,083 drugs. Click any drug to see the details.
2 of the 3 ingredients in Fibermucil interact with drugs. Each result below shows which ingredient is responsible. Dietary Fiber Lactobacillus sporogenes
Alogliptin, MetforminKazano
How Alogliptin, Metformin interacts with Fibermucil — through 1 ingredient. Tap an ingredient for the detail:
Dietary FiberOral Drugs, Metformin (glucophage) Moderate
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Alogliptin, Metformin interactionAmikacinAmikin, Arikayce
How Amikacin interacts with Fibermucil — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus SporogenesAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Lactobacillus Sporogenes + Amikacin interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Amikacin interactionAmoxicillinAmix, Amoram, Amoxident, Amoxil Capsules, Amoxil Injection, Galenamox +3 more
How Amoxicillin interacts with Fibermucil — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus SporogenesAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Lactobacillus Sporogenes + Amoxicillin interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Amoxicillin interactionAmoxicillin VeterinaryBiomox
How Amoxicillin Veterinary interacts with Fibermucil — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus SporogenesAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Lactobacillus Sporogenes + Amoxicillin Veterinary interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Amoxicillin Veterinary interactionAmoxicillin, Clavulanate PotassiumAugmentin, Augmentin '125/31 SF', Augmentin '250/62 SF', Augmentin XR, Augmentin-Duo 400/57, Clavulin
How Amoxicillin, Clavulanate Potassium interacts with Fibermucil — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus SporogenesAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Lactobacillus Sporogenes + Amoxicillin, Clavulanate Potassium interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Amoxicillin, Clavulanate Potassium interactionAmoxicillin, Omeprazole Magnesium, RifabutinTalicia
How Amoxicillin, Omeprazole Magnesium, Rifabutin interacts with Fibermucil — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus SporogenesAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Lactobacillus Sporogenes + Amoxicillin, Omeprazole Magnesium, Rifabutin interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Amoxicillin, Omeprazole Magnesium, Rifabutin interactionAmphotericin, TetracyclineMysteclin-F
How Amphotericin, Tetracycline interacts with Fibermucil — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus SporogenesAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Lactobacillus Sporogenes + Amphotericin, Tetracycline interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Amphotericin, Tetracycline interactionAmpicillinOmnipen, Omnipen-N, Penbritin, Principen, Rimacillin
How Ampicillin interacts with Fibermucil — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus SporogenesAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Lactobacillus Sporogenes + Ampicillin interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Ampicillin interactionAmpicillin, SulbactamUnasyn
How Ampicillin, Sulbactam interacts with Fibermucil — through 1 ingredient. Tap an ingredient for the detail:
Lactobacillus SporogenesAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Lactobacillus Sporogenes + Ampicillin, Sulbactam interactionAvibactam Sodium, CeftazidimeAvycaz
How Avibactam Sodium, Ceftazidime interacts with Fibermucil — through 1 ingredient. Tap an ingredient for the detail:
Lactobacillus SporogenesAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Lactobacillus Sporogenes + Avibactam Sodium, Ceftazidime interactionAzithromycinAzasite, Zithromax, Zmax
How Azithromycin interacts with Fibermucil — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus SporogenesAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Lactobacillus Sporogenes + Azithromycin interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Azithromycin interactionAztreonamAzactam
How Aztreonam interacts with Fibermucil — through 1 ingredient. Tap an ingredient for the detail:
Lactobacillus SporogenesAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Lactobacillus Sporogenes + Aztreonam interactionBacampicillinPenglobe
How Bacampicillin interacts with Fibermucil — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus SporogenesAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Lactobacillus Sporogenes + Bacampicillin interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Bacampicillin interactionBacitracinBaci-IM, Baciguent, Bacitracin Ointment
How Bacitracin interacts with Fibermucil — through 1 ingredient. Tap an ingredient for the detail:
Lactobacillus SporogenesAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Lactobacillus Sporogenes + Bacitracin interactionBenznidazoleBenznidazole
How Benznidazole interacts with Fibermucil — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus SporogenesAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Lactobacillus Sporogenes + Benznidazole interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Benznidazole interactionBismuth Subsalicylate, Metronidazole, TetracyclineHelidac
How Bismuth Subsalicylate, Metronidazole, Tetracycline interacts with Fibermucil — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus SporogenesAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Lactobacillus Sporogenes + Bismuth Subsalicylate, Metronidazole, Tetracycline interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Bismuth Subsalicylate, Metronidazole, Tetracycline interactionCanagliflozin, MetforminInvokamet
How Canagliflozin, Metformin interacts with Fibermucil — through 1 ingredient. Tap an ingredient for the detail:
Dietary FiberOral Drugs, Metformin (glucophage) Moderate
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Canagliflozin, Metformin interactionCanagliflozin, Metformin HydrochlorideInvokamet XR
How Canagliflozin, Metformin Hydrochloride interacts with Fibermucil — through 1 ingredient. Tap an ingredient for the detail:
Dietary FiberMetformin (glucophage), Oral Drugs Moderate
Interaction Summary
Theoretically, black psyllium might increase the therapeutic and adverse effects of metformin.
Read the full Dietary Fiber + Canagliflozin, Metformin Hydrochloride interactionCapreomycinCapastat
How Capreomycin interacts with Fibermucil — through 1 ingredient. Tap an ingredient for the detail:
Lactobacillus SporogenesAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Lactobacillus Sporogenes + Capreomycin interactionCarbamazepineCarbatrol, Carnexiv, Equetro, Tegretol, Tegretol XR
How Carbamazepine interacts with Fibermucil — through 1 ingredient. Tap an ingredient for the detail:
Dietary FiberCarbamazepine (tegretol), Oral Drugs Moderate
Interaction Summary
Theoretically, black psyllium might reduce the effects of carbamazepine and increase the risk for convulsions.
Read the full Dietary Fiber + Carbamazepine interactionCarbenicillin Indanyl SodiumGeocillin
How Carbenicillin Indanyl Sodium interacts with Fibermucil — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus SporogenesAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Lactobacillus Sporogenes + Carbenicillin Indanyl Sodium interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Carbenicillin Indanyl Sodium interactionCefaclorCeclor, Ceclor CD
How Cefaclor interacts with Fibermucil — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus SporogenesAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Lactobacillus Sporogenes + Cefaclor interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Cefaclor interactionCefadroxilCef-Tab, Duricef, Ultracef
How Cefadroxil interacts with Fibermucil — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus SporogenesAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Lactobacillus Sporogenes + Cefadroxil interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Cefadroxil interactionCefamandoleMandol
How Cefamandole interacts with Fibermucil — through 1 ingredient. Tap an ingredient for the detail:
Lactobacillus SporogenesAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Lactobacillus Sporogenes + Cefamandole interactionCefazolinAncef
How Cefazolin interacts with Fibermucil — through 1 ingredient. Tap an ingredient for the detail:
Lactobacillus SporogenesAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Lactobacillus Sporogenes + Cefazolin interactionCefdinirOmnicef
How Cefdinir interacts with Fibermucil — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus SporogenesAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Lactobacillus Sporogenes + Cefdinir interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Cefdinir interactionCefditoren PivoxilSpectracef
How Cefditoren Pivoxil interacts with Fibermucil — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus SporogenesAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Lactobacillus Sporogenes + Cefditoren Pivoxil interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Cefditoren Pivoxil interactionCefepimeMaxipime
How Cefepime interacts with Fibermucil — through 1 ingredient. Tap an ingredient for the detail:
Lactobacillus SporogenesAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Lactobacillus Sporogenes + Cefepime interactionCefiderocol Sulfate TosylateFetroja
How Cefiderocol Sulfate Tosylate interacts with Fibermucil — through 1 ingredient. Tap an ingredient for the detail:
Lactobacillus SporogenesAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Lactobacillus Sporogenes + Cefiderocol Sulfate Tosylate interactionCefiximeSuprax
How Cefixime interacts with Fibermucil — through 2 ingredients. Tap an ingredient for the detail:
Lactobacillus SporogenesAntibiotic Drugs Moderate
Interaction Summary
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B.
Read the full Lactobacillus Sporogenes + Cefixime interactionDietary FiberOral Drugs Minor
Interaction Summary
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Read the full Dietary Fiber + Cefixime interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Fibermucil with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Dietary Fiber
Carbamazepine (Tegretol)
Theoretically, black psyllium might reduce the effects of carbamazepine and increase the risk for convulsions.
Theoretically, black psyllium might reduce carbamazepine absorption. A preliminary study using blond psyllium reported decreased carbamazepine bioavailability due to binding of the drug to psyllium, as well as reduction of available fluid in the gut for dissolution of the drug. This interaction may also occur with black psyllium.
Lithium
Theoretically, taking black psyllium at the same time as lithium might reduce lithium absorption.
The fiber in black psyllium might reduce lithium absorption and plasma levels. Some case reports describe a reduction in plasma lithium levels with concomitant administration of blond psyllium. This was reversed when psyllium was stopped. This interaction may also occur with black psyllium.
Metformin (Glucophage)
Theoretically, black psyllium might increase the therapeutic and adverse effects of metformin.
Animal research shows that concurrent consumption of blond psyllium with metformin slows and increases the absorption of metformin. This interaction may also occur with black psyllium. To avoid changes in absorption, take psyllium 30-60 minutes after metformin.
Olanzapine (Zyprexa)
Theoretically, taking black psyllium at the same time as olanzapine might reduce olanzapine absorption.
The fiber in black psyllium might decrease the absorption of olanzapine. A single case report describes a reduction in the effectiveness of olanzapine when it was concomitantly administered with an unspecified type of psyllium 3 grams orally twice daily. This effect was reversed when psyllium was stopped.
Digoxin (Lanoxin)
Theoretically, taking black psyllium at the same time as digoxin might reduce digoxin absorption and decrease digoxin levels.
Psyllium might bind digoxin in the gut. However, some clinical evidence suggests that psyllium does not impact digoxin absorption.
Ethinyl Estradiol
Theoretically, taking black psyllium at the same time as ethinyl estradiol might alter levels of estradiol.
Concurrent use of blond psyllium with ethinyl estradiol results in a slight increase in the extent of ethinyl estradiol absorption and a slower rate of absorption. This is unlikely to be clinically significant.
Oral Drugs
Theoretically, psyllium might increase, decrease, or have no effect on the absorption of oral drugs.
Psyllium seems to have variable effects on drug absorption. To avoid changes in absorption, take psyllium 30-60 minutes after oral medications. Animal research shows that blond psyllium delays and increases the absorption of metformin and ethinyl estradiol. Case reports and animal research suggest that blond psyllium might reduce absorption of lithium, digoxin, olanzapine, and carbamazepine. Finally, some pharmacokinetic studies show that psyllium does not affect the absorption of levothyroxine or warfarin. Although many of these studies evaluated blond psyllium, the fiber content in black psyllium may have similar effects.
Lactobacillus sporogenes
Antibiotic Drugs
Theoretically, taking antibiotics with Bacillus coagulans might decrease the effectiveness of B. coagulans.
B. coagulans preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and B. coagulans preparations by at least two hours.
Brand information
Manufacturer and brand details for Fibermucil, from the product label.
ProCaps Laboratories
See all ProCaps Laboratories products- Name
- ProCaps Laboratories
- City
- Henderson
- State
- NV
- ZipCode
- 89011
- Phone Number
- 800.800.1200
- Web Address
- www.ProCapsLabs.com
Fibermucil by ProCaps Laboratories: Common Questions
Does Fibermucil by ProCaps Laboratories interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Can I take this while I'm on an antibiotic?
Does this work for diarrhea caused by antibiotics?
Is this safe for someone with a weakened immune system?
What does the probiotic Lactobacillus sporogenes actually do?
Can I use this while pregnant or breastfeeding?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Fibermucil’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Black Psyllium
Interacts with 2,025 drugsBlack psyllium is a soluble-fiber supplement made from the seeds of a Plantago plant, used mostly to ease constipation and support digestive health. It is best known and most studied for rel...
Read the full Black Psyllium monograph → Herb & supplement monographBacillus Coagulans
Interacts with 182 drugsBacillus coagulans is a spore-forming probiotic that survives stomach acid well and may help with some digestive problems such as IBS, constipation, and certain types of diarrhea. The eviden...
Read the full Bacillus Coagulans monograph →Sources & How We Checked
Fibermucil's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 38 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Black Psyllium 18 references
- McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
- Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
- Covington TR, et al. Handbook of Nonprescription Drugs. 11th ed. Washington, DC: American Pharmaceutical Association, 1996.
- Etman M. Effect of a bulk forming laxative on the bioavailablility of carbamazepine in man. Drug Dev Ind Pharm 1995;21:1901-6.
- Perlman BB. Interaction between lithium salts and ispaghula husk. Lancet 1990;335:416.
- Vaswani SK, Hamilton RG, Valentine MD, Adkinson NF. Psyllium laxative-induced anaphylaxis, asthma, and rhinitis. Allergy 1996;51:266-8. PubMed
- Lantner RR, Espiritu BR, Zumerchik P, Tobin MC. Anaphylaxis following ingestion of a psyllium-containing cereal. JAMA 1990;264:2534-6. DOI
- Kaplan MJ. Anaphylactic reaction to "Heartwise." N Engl J Med 1990;323:1072-3. DOI
- Nordstrom M, Melander A, Robertsson E, Steen B. Influence of wheat bran and of a bulk-forming ispaghula cathartic on the bioavailability of digoxin in geriatric in-patients. Drug Nutr Interact 1987;5:67-9..
- Robinson DS, Benjamin DM, McCormack JJ. Interaction of warfarin and nonsystemic gastrointestinal drugs. Clin Pharmacol Ther 1971;12:491-5. PubMed
- Garcia JJ, Fernandez N, Diez MJ, et al. Influence of two dietary fibers in the oral bioavailability and other pharmacokinetic parameters of ethinyloestradiol. Contraception 2000;62:253-7. PubMed
- Fernandez N, Lopez C, Díez R, et al. Drug interactions with the dietary fiber Plantago ovata husk. Expert Opin Drug Metab Toxicol 2012;8(11):1377-86.
- Semen plantaginis in: WHO Monographs on Selected Medicinal Plants, volume 1. World Health Organization, Geneva, 1999. Available at http://apps.who.int/medicinedocs/en/d/Js2200e/. Accessed November 26, 1026.
- Code of Federal Regulations, Title 21 (21CFR 101.17). Food labeling warning, notice, and safe handling statements. Available at www.ecfr.gov/cgi-bin/text-idx?SID=20f647d3b74161501f46564b915b4048&mc=true&node=se21.2.101_117&rgn=div8. Accessed December 3, 2
- Code of Federal Regulations, Title 21 (21CFR 201.319). Specific labeling requirements - water-soluble gums, hydrophilic gums, and hydrophilic mucilloids. Available at www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=201.319. Accessed Dece
- Diez R, Garcia JJ, Diez MJ, Sierra M, Sahagun AM, Fernandez N. Influence of Plantago ovata husk (dietary fiber) on the bioavailability and other pharmacokinetic parameters of metformin in diabetic rabbits. BMC Complement Altern Med. 2017 Jun 7;17(1):298. PubMed
- Chiu AC, Sherman SI. Effects of pharmacological fiber supplements on levothyroxine absorption. Thyroid. 1998;8(8):667-71. PubMed
- Merrick C, Madden CA, Capurso NA. A Case of Blunted Orally Disintegrating Olanzapine Effect Due to Coadministered Psyllium. J Clin Psychiatry 2021;82(2):20cr13633. PubMed
Bacillus Coagulans 20 references
- Saxelin M, Chuang NH, Chassy B, et al. Lactobacilli and bacteremia in southern Finland 1989-1992. Clin Infect Dis 1996;22:564-6. PubMed
- Tynkkynen S, Singh KV, Varmanen P. Vancomycin resistance factor of Lactobacillus rhamnosus GG in relation to enterococcal vancomycin resistance (van) genes. Int J Food Microbiol 1998;41:195-204. PubMed
- Klein G, Zill E, Schindler R, et al. Peritonitis associated with vancomycin-resistant Lactobacillus rhamnosus in a continuous ambulatory peritoneal dialysis patient; organism identification, antibiotic therapy, and case report. J Clin Microbiol 1998;36:
- Kalima P, Masterton RG, Roddie PH, et al. Lactobacillus rhamnosus infection in a child following bone marrow transplant. J Infect 1996;32:165-7. PubMed
- Goldin BR. Health Benefits of probiotics. Br J Nutr 1998;80:S203-7. DOI
- Rautio M, Jousimies-Somer H, Kauma H, et al. Liver abscess due to Lactobacillus rhamnosus strain indistinguishable from L. rhamnosus strain GG. Clin Infect Dis 1999;28:1159-60.
- MacGregor G, Smith AJ, Thakker B, Kinsella J. Yoghurt biotherapy: contraindicated in immunosuppressed patients? Postgrad Med J 2002;78:366-7. PubMed
- Land MH, Rouster-Stevens K, Woods CR, et al. Lactobacillus sepsis associated with probiotic therapy. Pediatrics 2005;115:178-81.
- De Groote MA, Frank DN, Dowell E, et al. Lactobacillus rhamnosus GG bacteremia associated with probiotic use in a child with short gut syndrome. Pediatr Infect Dis J 2005;24:278-80. PubMed
- Vahabnezhad E, Mochon AB, Wozniak LJ, Ziring DA. Lactobacillus bacteremia associated with probiotic use in a pediatric patient with ulcerative colitis. J Clin Gastroenterol. 2013;47(5):437-9. PubMed
- Pruccoli G, Silvestro E, Pace Napoleone C, Aidala E, Garazzino S, Scolfaro C. Are probiotics safe? Bifidobacterium bacteremia in a child with severe heart failure. Infez Med. 2019;27(2):175-178.
- Sendil S, Shrimanker I, Mansoora Q, Goldman J, Nookala VK. Lactobacillus rhamnosus bacteremia in an immunocompromised renal transplant patient. Cureus. 2020;12(2):e6887. PubMed
- Albarillo FS, Shah U, Joyce C, Slade D. Lactobacillus rhamnosus Infection: A single-center 4-year descriptive analysis. J Glob Infect Dis. 2020;12(3):119-123. PubMed
- Pasala S, Singer L, Arshad T, Roach K. Lactobacillus endocarditis in a healthy patient with probiotic use. IDCases. 2020;22:e00915. PubMed
- Agrawal S, Tuchman ES, Bruce MJ, Theodorou ME. Fatal Lactobacillus endocarditis in a patient with transcatheter aortic valve replacement. BMJ Case Rep. 2020;13(11):e236835.
- Antoun M, Hattab Y, Akhrass FA, Hamilton LD. Uncommon pathogen, Lactobacillus, causing infective endocarditis: Case report and review. Case Rep Infect Dis. 2020;2020:8833948. PubMed
- Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
- Franko B, Vaillant M, Recule C, Vautrin E, et al. Lactobacillus paracasei endocarditis in a consumer of probiotics. Med Mal Infect. 2013;43(4):171-3. PubMed
- Campbell RE, Miller A, Afroze A. Native valve endocarditis secondary to Lactobacillus paracasei bacteremia. Consultant. 2020;60(9):27-8. DOI
- Kato K, Funabashi N, Takaoka H, et al. Lactobacillus paracasei endocarditis in a consumer of probiotics with advanced and severe bicuspid aortic valve stenosis complicated with diffuse left ventricular mid-layer fibrosis. Int J Cardiol. 2016;224:157-161. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC