Fish Oil Pearls Ingredients & Drug Interactions
by Nature Made
What is this page for?
First and foremost: checking Fish Oil Pearls against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Fish Oil Pearls is a dietary supplement by Nature Made with 1 active ingredient. Its ingredients are commonly taken for brain and cognitive health, eye and vision health, fetal and infant development.Based on those ingredients, 375 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Omega-3 Fatty Acid Ethyl Ester. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Fish Oil Pearls by Nature Made
Ask about any prescription or over-the-counter medication and we check it for interactions with Fish Oil Pearls by Nature Made — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Fish Oil Pearls by Nature Made
Four independent checks of what is known — a summary of the available information, not a grade of the product itself.
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
None of the active ingredients could be matched to our evidence database, so intended use can't be graded.
Why this rating?
- None of the active ingredients could be matched to a HelloPharmacist monograph, so intended use can't be graded against our evidence data.
Every active ingredient lists its own amount on the label.
Why this rating?
- The label discloses an exact amount for 1 of its 1 active ingredient.
- “Total Omega-3 Fatty Acids Ethyl Esters” is listed as a grouped ingredient — the label gives one combined amount (550 mg) without saying how much of each component you get.
- “Omega-3 Fatty Acid Ethyl Ester” is listed as a grouped ingredient — the label gives one combined amount (918 mg) without saying how much of each component you get.
- “Total DHA, EPA” is listed as a grouped ingredient — the label gives one combined amount (500 mg) without saying how much of each component you get.
None of the active ingredients could be matched to our interaction database.
Why this rating?
- We couldn't match any ingredient to a HelloPharmacist monograph, so there was nothing to check interactions against.
None of the active ingredients could be matched to our safety data.
Why this rating?
- We couldn't match any ingredient to a HelloPharmacist monograph, so there was no safety data to measure.
HelloPharmacist summaryFully disclosed formula with no assessable stated purpose. Medication interactions could not be assessed, and safety information could not be assessed.
Assessment coverage: 0 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Aug 23, 2020.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Fish Oil Pearls, straight from the product label.
| Brand | Nature Made |
|---|---|
| Net contents | 300 Softgel(s) |
| Market status | On market |
| Date entered into DSLD | Aug 23, 2020 |
| DSLD ID | 231416 |
| Product type | Fat/fatty Acid |
| Supplement form | Softgel Capsule |
| Dietary claims / uses | Nutrient, All Other, Qualified Health, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Fish Oil Pearls by Nature Made, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Calories | 10 Calorie(s) | -- |
| Total Carbohydrates | 1 Gram(s) | 1% |
| Cholesterol | 5 mg | 2% |
| Total Fat | 0.5 Gram(s) | 1% |
| Docosahexaenoic Acid Ethyl Ester | 275 mg | -- |
| Total Omega-3 Fatty Acids Ethyl Esters | 550 mg | -- |
| Omega-3 Fatty Acid Ethyl Ester | 918 mg | -- |
| Total DHA, EPA | 500 mg | -- |
Other ingredients: Gelatin, Glycerin, Water, Tocopherols
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements
#1 pharmacist recommended vitamin & supplement brand
Based on Pharmacy Times Survey of pharmacists recommending Omega-3/fish oil supplements.
Formula
Omega-3 from Fish Oil Pearls 550 mg Omega-3 per serving Smallest fish oil
Supportive but not conclusive research shows that consumption of EPA and DHA omega-3 fatty acids may reduce the risk of coronary heart disease. (See nutrition information for total fat and cholesterol content.)
Fish oils used to produce this product are derived from wild caught ocean fish, not farm raised fish.
Seals/Symbols
USP Verified Dietary Supplement
Formulation
Helps support a healthy heart
No color added No artificial flavors Gluten free
Fish oil country of origin: Norway, Canada, Columbia or Peru. Encapsulated and quality tested in the USA. USP has tested and verified ingredients, potency and manufacturing process. USP sets official standards for dietary supplements. www.uspverified.org
Pearl shaped softgel. Smaller than all other Nature Made fish oil products.
Purified to remove PCBs, dioxins and furans, and mercury to ensure levels below 0.09 ppm, 2 ppt WHO TEQs, and 0.1 ppm respectively.
FDA Statement of Identity
Dietary Supplement
FDA Disclaimer Statement
This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Suggested/Recommended/Usage/Directions
Suggested use: Adults, take 3 softgels daily with water and a meal for optimal absorption.
Storage
Store tightly closed, in a cool, dry place, out of reach of children.
Precautions
Store tightly closed, in a cool, dry place, out of reach of children.
Do not use if imprinted seal under cap is broken or missing.
Caution: If you are pregnant, nursing, taking medications, or have blood clotting issues, consult your physician before use.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Fish Oil Pearls by Nature Made label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Fish Oil Pearls by Nature Made
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size3 Softgel(s) Dosage formSoftgel Capsule Servings per container100 Amounts shown are per serving.
Omega-3 Fatty Acid Ethyl Ester
Interacts with375 drugs
DHA is an omega-3 fatty acid found in fatty fish and algae that is a building block for the brain, nervous system, and eyes. It is widely used and gen...
Omega-3 Fatty Acid Ethyl Ester monograph & interactions- › Total Omega-3 Fatty Acids Ethyl Esters
Other (inactive) ingredients: Gelatin, Glycerin, Water, Tocopherols. These complete the product’s ingredient list but are not active constituents.
Fish Oil Pearls by Nature Made Drug Interactions
Fish Oil Pearls contains a single active ingredient, and it has known interactions with 375 medications. Here’s the picture, then you can look up your own drug.
Want to check YOUR meds against Fish Oil Pearls?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Fish Oil Pearls interact with 375 drugs. Click any drug to see the details.
1 of the 1 ingredient in Fish Oil Pearls interact with drugs. Each result below shows which ingredient is responsible. Omega-3 Fatty Acid Ethyl Ester
AbciximabReoPro
How Abciximab interacts with Fish Oil Pearls — through 1 ingredient. Tap an ingredient for the detail:
Omega-3 Fatty Acid Ethyl EsterAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, DHA may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Omega-3 Fatty Acid Ethyl Ester + Abciximab interactionAbrocitinibCibinqo
How Abrocitinib interacts with Fish Oil Pearls — through 1 ingredient. Tap an ingredient for the detail:
Omega-3 Fatty Acid Ethyl EsterAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, DHA may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Omega-3 Fatty Acid Ethyl Ester + Abrocitinib interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Fish Oil Pearls — through 1 ingredient. Tap an ingredient for the detail:
Omega-3 Fatty Acid Ethyl EsterAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking DHA with antidiabetes drugs might reduce the effects of these medications.
Read the full Omega-3 Fatty Acid Ethyl Ester + Acarbose interactionAcebutololRhotral, Sectral
How Acebutolol interacts with Fish Oil Pearls — through 1 ingredient. Tap an ingredient for the detail:
Omega-3 Fatty Acid Ethyl EsterAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking DHA with antihypertensive drugs might increase the risk of hypotension.
Read the full Omega-3 Fatty Acid Ethyl Ester + Acebutolol interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Fish Oil Pearls — through 1 ingredient. Tap an ingredient for the detail:
Omega-3 Fatty Acid Ethyl EsterAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, DHA may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Omega-3 Fatty Acid Ethyl Ester + Acenocoumarol interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Fish Oil Pearls — through 1 ingredient. Tap an ingredient for the detail:
Omega-3 Fatty Acid Ethyl EsterAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, DHA may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Omega-3 Fatty Acid Ethyl Ester + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Fish Oil Pearls — through 1 ingredient. Tap an ingredient for the detail:
Omega-3 Fatty Acid Ethyl EsterAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, DHA may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Omega-3 Fatty Acid Ethyl Ester + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, IbuprofenCombogesic
How Acetaminophen, Ibuprofen interacts with Fish Oil Pearls — through 1 ingredient. Tap an ingredient for the detail:
Omega-3 Fatty Acid Ethyl EsterAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, DHA may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Omega-3 Fatty Acid Ethyl Ester + Acetaminophen, Ibuprofen interactionAcetazolamideAk-Zol, Diamox
How Acetazolamide interacts with Fish Oil Pearls — through 1 ingredient. Tap an ingredient for the detail:
Omega-3 Fatty Acid Ethyl EsterAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking DHA with antihypertensive drugs might increase the risk of hypotension.
Read the full Omega-3 Fatty Acid Ethyl Ester + Acetazolamide interactionAcetohexamideDymelor
How Acetohexamide interacts with Fish Oil Pearls — through 1 ingredient. Tap an ingredient for the detail:
Omega-3 Fatty Acid Ethyl EsterAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking DHA with antidiabetes drugs might reduce the effects of these medications.
Read the full Omega-3 Fatty Acid Ethyl Ester + Acetohexamide interactionAcetylsalicylic AcidEntrophen
How Acetylsalicylic Acid interacts with Fish Oil Pearls — through 1 ingredient. Tap an ingredient for the detail:
Omega-3 Fatty Acid Ethyl EsterAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, DHA may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Omega-3 Fatty Acid Ethyl Ester + Acetylsalicylic Acid interactionAlbiglutideTanzeum
How Albiglutide interacts with Fish Oil Pearls — through 1 ingredient. Tap an ingredient for the detail:
Omega-3 Fatty Acid Ethyl EsterAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking DHA with antidiabetes drugs might reduce the effects of these medications.
Read the full Omega-3 Fatty Acid Ethyl Ester + Albiglutide interactionAliskirenTekturna
How Aliskiren interacts with Fish Oil Pearls — through 1 ingredient. Tap an ingredient for the detail:
Omega-3 Fatty Acid Ethyl EsterAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking DHA with antihypertensive drugs might increase the risk of hypotension.
Read the full Omega-3 Fatty Acid Ethyl Ester + Aliskiren interactionAlogliptinNesina
How Alogliptin interacts with Fish Oil Pearls — through 1 ingredient. Tap an ingredient for the detail:
Omega-3 Fatty Acid Ethyl EsterAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking DHA with antidiabetes drugs might reduce the effects of these medications.
Read the full Omega-3 Fatty Acid Ethyl Ester + Alogliptin interactionAlogliptin, MetforminKazano
How Alogliptin, Metformin interacts with Fish Oil Pearls — through 1 ingredient. Tap an ingredient for the detail:
Omega-3 Fatty Acid Ethyl EsterAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking DHA with antidiabetes drugs might reduce the effects of these medications.
Read the full Omega-3 Fatty Acid Ethyl Ester + Alogliptin, Metformin interactionAlogliptin, PioglitazoneOseni
How Alogliptin, Pioglitazone interacts with Fish Oil Pearls — through 1 ingredient. Tap an ingredient for the detail:
Omega-3 Fatty Acid Ethyl EsterAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, taking DHA with antidiabetes drugs might reduce the effects of these medications.
Read the full Omega-3 Fatty Acid Ethyl Ester + Alogliptin, Pioglitazone interactionAlteplase, TpaActilyse, Activase
How Alteplase, Tpa interacts with Fish Oil Pearls — through 1 ingredient. Tap an ingredient for the detail:
Omega-3 Fatty Acid Ethyl EsterAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, DHA may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Omega-3 Fatty Acid Ethyl Ester + Alteplase, Tpa interactionAluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium HydroxideAscriptin Codeine #2
How Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interacts with Fish Oil Pearls — through 1 ingredient. Tap an ingredient for the detail:
Omega-3 Fatty Acid Ethyl EsterAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, DHA may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Omega-3 Fatty Acid Ethyl Ester + Aluminum Hydroxide, Aspirin, Codeine Phosphate, Magnesium Hydroxide interactionAluminum Hydroxide, Aspirin, Magnesium HydroxideAscriptin
How Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interacts with Fish Oil Pearls — through 1 ingredient. Tap an ingredient for the detail:
Omega-3 Fatty Acid Ethyl EsterAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, DHA may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Omega-3 Fatty Acid Ethyl Ester + Aluminum Hydroxide, Aspirin, Magnesium Hydroxide interactionAmbrisentanLetairis, Volibris
How Ambrisentan interacts with Fish Oil Pearls — through 1 ingredient. Tap an ingredient for the detail:
Omega-3 Fatty Acid Ethyl EsterAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking DHA with antihypertensive drugs might increase the risk of hypotension.
Read the full Omega-3 Fatty Acid Ethyl Ester + Ambrisentan interactionAmilorideAmilamont, Midamor
How Amiloride interacts with Fish Oil Pearls — through 1 ingredient. Tap an ingredient for the detail:
Omega-3 Fatty Acid Ethyl EsterAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking DHA with antihypertensive drugs might increase the risk of hypotension.
Read the full Omega-3 Fatty Acid Ethyl Ester + Amiloride interactionAmiloride, HydrochlorothiazideAmil-Co, Amilzide, Moduret 25, Moduretic
How Amiloride, Hydrochlorothiazide interacts with Fish Oil Pearls — through 1 ingredient. Tap an ingredient for the detail:
Omega-3 Fatty Acid Ethyl EsterAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking DHA with antihypertensive drugs might increase the risk of hypotension.
Read the full Omega-3 Fatty Acid Ethyl Ester + Amiloride, Hydrochlorothiazide interactionAmlodipineNorliqva
How Amlodipine interacts with Fish Oil Pearls — through 1 ingredient. Tap an ingredient for the detail:
Omega-3 Fatty Acid Ethyl EsterAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking DHA with antihypertensive drugs might increase the risk of hypotension.
Read the full Omega-3 Fatty Acid Ethyl Ester + Amlodipine interactionAmlodipine BenzoateKaterzia
How Amlodipine Benzoate interacts with Fish Oil Pearls — through 1 ingredient. Tap an ingredient for the detail:
Omega-3 Fatty Acid Ethyl EsterAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking DHA with antihypertensive drugs might increase the risk of hypotension.
Read the full Omega-3 Fatty Acid Ethyl Ester + Amlodipine Benzoate interactionAmlodipine BesilateIstin
How Amlodipine Besilate interacts with Fish Oil Pearls — through 1 ingredient. Tap an ingredient for the detail:
Omega-3 Fatty Acid Ethyl EsterAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking DHA with antihypertensive drugs might increase the risk of hypotension.
Read the full Omega-3 Fatty Acid Ethyl Ester + Amlodipine Besilate interactionAmlodipine BesylateNorvasc
How Amlodipine Besylate interacts with Fish Oil Pearls — through 1 ingredient. Tap an ingredient for the detail:
Omega-3 Fatty Acid Ethyl EsterAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking DHA with antihypertensive drugs might increase the risk of hypotension.
Read the full Omega-3 Fatty Acid Ethyl Ester + Amlodipine Besylate interactionAmlodipine Besylate, BenazeprilLotrel
How Amlodipine Besylate, Benazepril interacts with Fish Oil Pearls — through 1 ingredient. Tap an ingredient for the detail:
Omega-3 Fatty Acid Ethyl EsterAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking DHA with antihypertensive drugs might increase the risk of hypotension.
Read the full Omega-3 Fatty Acid Ethyl Ester + Amlodipine Besylate, Benazepril interactionAmlodipine, CelecoxibConsensi
How Amlodipine, Celecoxib interacts with Fish Oil Pearls — through 1 ingredient. Tap an ingredient for the detail:
Omega-3 Fatty Acid Ethyl EsterAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking DHA with antihypertensive drugs might increase the risk of hypotension.
Read the full Omega-3 Fatty Acid Ethyl Ester + Amlodipine, Celecoxib interactionAmmonium ChlorideAmmonium Chloride
How Ammonium Chloride interacts with Fish Oil Pearls — through 1 ingredient. Tap an ingredient for the detail:
Omega-3 Fatty Acid Ethyl EsterAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking DHA with antihypertensive drugs might increase the risk of hypotension.
Read the full Omega-3 Fatty Acid Ethyl Ester + Ammonium Chloride interactionAnacaulase-bcdbNexoBrid
How Anacaulase-bcdb interacts with Fish Oil Pearls — through 1 ingredient. Tap an ingredient for the detail:
Omega-3 Fatty Acid Ethyl EsterAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, DHA may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Read the full Omega-3 Fatty Acid Ethyl Ester + Anacaulase-bcdb interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Fish Oil Pearls with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Omega-3 Fatty Acid Ethyl Ester
Anticoagulant/Antiplatelet Drugs
Theoretically, DHA may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Although some clinical evidence suggests that DHA might reduce collagen-stimulated platelet aggregation and thromboxane release, most clinical evidence suggests that DHA alone does not affect blood clotting. However, theoretically, when given in combination with EPA as fish oil, concomitant use with anticoagulant or antiplatelet drugs (including aspirin) might increase risk of bleeding.
Antidiabetes Drugs
Theoretically, taking DHA with antidiabetes drugs might reduce the effects of these medications.
In people with type 2 diabetes, including those taking oral hypoglycemic medications, DHA seems to increase fasting blood glucose levels.
Antihypertensive Drugs
Theoretically, taking DHA with antihypertensive drugs might increase the risk of hypotension.
Fish oils containing DHA can lower blood pressure and might have additive effects in patients treated with antihypertensives; use with caution.
Brand information
Manufacturer and brand details for Fish Oil Pearls, from the product label.
Nature Made
See all Nature Made products- Name
- Nature Made Nutritional Products
- City
- West Hills
- State
- CA
- ZipCode
- 91309-9903
- Phone Number
- 1-800-276-2878
- Web Address
- www.NatureMade.com
Fish Oil Pearls by Nature Made: Common Questions
Does Fish Oil Pearls by Nature Made interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Fish Oil Pearls is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Fish Oil Pearls’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Fish Oil Pearls's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 49 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Docosahexaenoic Acid (dha) 49 references
- Akedo I, Ishikawa H, Nakamura T, et al. Three cases with familial adenomatous polyposis diagnosed as having malignant lesions in the course of a long-term trial using docosahexanoic acid (DHA)-concentrated fish oil capsules (abstract). Jpn J Clin Oncol PubMed
- Prisco D, Paniccia R, Bandinelli B, et al. Effect of medium-term supplementation with a moderate dose of n-3 polyunsaturated fatty acids on blood pressure in mild hypertensive patients. Thromb Res 1998;1:105-12.
- Grimsgaard S, Bonaa KH, Hansen JB, Nordoy A. Highly purified eicosapentaenoic acid and docosahexaenoic acid in humans have similar triacylglycerol-lowering effects but divergent effects on serum fatty acids. Am J Clin Nutr 1997;66:649-59.
- Toft I, Bonaa KH, Ingebretsen OC, et al. Effects of n-3 polyunsaturated fatty acids on glucose homeostasis and blood pressure in essential hypertension. A randomized, controlled trial. Ann Intern Med 1995;123:911-8.
- Sacks FM, Hebert P, Appel LJ, et al. Short report: the effect of fish oil on blood pressure and high-density lipoprotein-cholesterol levels in phase I of the trials of hypertension prevention. J Hypertens 1994;12:209-13.
- Vandongen R, Mori TA, Burke V, et al. Effects on blood pressure of omega 3 fats in subjects at increased risk of cardiovascular disease. Hypertension 1993;22:371-9. PubMed
- FDA. Center for Food Safety and Applied Nutrition. Letter regarding dietary supplement health claim for omega-3 fatty acids and coronary heart disease. Available at: http://www.fda.gov/ohrms/dockets/dockets/95s0316/95s-0316-Rpt0272-38-Appendix-D-Reference
- Pedersen HS, Mulvad G, Seidelin KN, et al. N-3 fatty acids as a risk factor for haemorrhagic stroke. Lancet 1999;353:812-3. PubMed
- Ito Y, Suzuki K, Imai H, et al. Effects of polyunsaturated fatty acids on atrophic gastritis in a Japanese population. Cancer Lett 2001;163:171-8. PubMed
- Kris-Ehterton PM, Harris WS, Appel LJ, et al. Fish consumption, fish oil, omega-3 fatty acids, and cardiovascular disease. Circulation 2002;106:2747-57. PubMed
- Woodman RJ, Mori TA, Burke V, et al. Effects of purified eicosapentaenoic and docosahexaenoic acids on glycemic control, blood pressure, and serum lipids in type 2 diabetic patients with treated hypertension. Am J Clin Nutr 2002;76:1007-15.. PubMed
- Marangell LB, Martinez JM, Zboyan HA, et al. A double-blind, placebo-controlled study of the omega-3 fatty acid docosahexaenoic acid in the treatment of major depression. Am J Psychiatry 2003;160:996-8.. PubMed
- Leng GC, Smith FB, Fowkes FG, et al. Relationship between plasma essential fatty acids and smoking, serum lipids, blood pressure and haemostatic and rheological factors. Prostaglandins Leukot Essent Fatty Acids 1994;51:101-8. PubMed
- Nelson GJ, Schmidt PS, Bartolini GL, et al. The effect of dietary docosahexaenoic acid on platelet function, platelet fatty acid composition, and blood coagulation in humans. Lipids 1997;32:1129-36. PubMed
- Wheaton DH, Hoffman DR, Locke KG, et al. Biological safety assessment of docosahexaenoic acid supplementation in a randomized clinical trial for X-linked retinitis pigmentosa. Arch Ophthalmol 2003;121:1269-78. PubMed
- Malcolm CA, McCulloch DL, Montgomery C, et al. Maternal docosahexaenoic acid supplementation during pregnancy and visual evoked potential development in term infants: a double blind, prospective, randomised trial. Arch Dis Child Fetal Neonatal Ed 2003;88: DOI
- Sanjurjo P, Ruiz-Sanz JI, Jimeno P, et al. Supplementation with docosahexaenoic acid in the last trimester of pregnancy: maternal-fetal biochemical findings. J Perinat Med 2004;32:132-6.
- Montgomery C, Speake BK, Cameron A, et al. Maternal docosahexaenoic acid supplementation and fetal accretion. Br J Nutr 2003;90:135-45. DOI
- Lauritzen L, Hoppe C, Straarup EM, Michaelsen KF. Maternal fish oil supplementation in lactation and growth during the first 2.5 years of life. Pediatr Res 2005;58:235-42. PubMed
- Hawkes JS, Bryan DL, Makrides M, et al. A randomized trial of supplementation with docosahexaenoic acid-rich tuna oil and its effects on the human milk cytokines interleukin 1 beta, interleukin 6, and tumor necrosis factor alpha. Am J Clin Nutr 2002;75:75
- Uauy R, Hoffman DR, Mena P, et al. Term infant studies of DHA and ARA supplementation on neurodevelopment: Results of randomized controlled trials. J Pediatr 2003;143:S17-25. PubMed
- Decsi, T., Campoy, C., and Koletzko, B. Effect of N-3 polyunsaturated fatty acid supplementation in pregnancy: the Nuheal trial. Adv.Exp Med Biol 2005;569:109-113. PubMed
- Mori, T. A., Bao, D. Q., Burke, V., Puddey, I. B., and Beilin, L. J. Docosahexaenoic acid but not eicosapentaenoic acid lowers ambulatory blood pressure and heart rate in humans. Hypertension 1999;34(2):253-260. PubMed
- Otto, S. J., van Houwelingen, A. C., and Hornstra, G. The effect of supplementation with docosahexaenoic and arachidonic acid derived from single cell oils on plasma and erythrocyte fatty acids of pregnant women in the second trimester. Prostaglandins Le PubMed
- Helland, I. B., Saugstad, O. D., Smith, L., Saarem, K., Solvoll, K., Ganes, T., and Drevon, C. A. Similar effects on infants of n-3 and n-6 fatty acids supplementation to pregnant and lactating women. Pediatrics 2001;108(5):E82. PubMed
- Nestel, P., Shige, H., Pomeroy, S., Cehun, M., Abbey, M., and Raederstorff, D. The n-3 fatty acids eicosapentaenoic acid and docosahexaenoic acid increase systemic arterial compliance in humans. Am.J.Clin.Nutr. 2002;76(2):326-330. PubMed
- Woodman, R. J., Mori, T. A., Burke, V., Puddey, I. B., Barden, A., Watts, G. F., and Beilin, L. J. Effects of purified eicosapentaenoic acid and docosahexaenoic acid on platelet, fibrinolytic and vascular function in hypertensive type 2 diabetic patients PubMed
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See these in context on the Docosahexaenoic Acid (dha) monograph →
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