Interactions on record — worth a quick check against your medications. Based on 1 of 2 ingredients. Check your meds →
Dietary supplement

FitTrim Ingredients & Drug Interactions

by Genesis Today

FitTrim label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 30, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking FitTrim against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

FitTrim is a dietary supplement by Genesis Today with 2 active ingredients. Its ingredients are commonly taken for antioxidant support, anti-inflammatory support, immune support.Based on those ingredients, 125 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Garcinia mangostana (fruit rind) extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against FitTrim by Genesis Today

Ask about any prescription or over-the-counter medication and we check it for interactions with FitTrim by Genesis Today — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of FitTrim by Genesis Today

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 30, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 2 active ingredients.
  • “FitTrim Cardiaslim Blend” is a proprietary blend — the label gives one combined amount (400 mg) without saying how much of each component you get.

FitTrim contains two active ingredients: Sphaeranthus indicus (flower heads) extract and Garcinia mangostana (fruit rind) extract, commonly known as mangosteen. The product also includes several inactive ingredients — a vegetarian capsule, microcrystalline cellulose (a binder), magnesium stearate, silicon dioxide, and rice hull concentrate — that help form and preserve the capsule.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Mangosteen's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: weight management and cardiovascular health.
  • We looked for evidence on: Obesity, weight loss, lipid management, metabolic health.
  • The closest evidence on file: Mangosteen is rated "Insufficient Reliable Evidence To Rate" for Obesity (Natural Medicines).

Mangosteen extract is possibly effective for periodontitis (gum infection and inflammation). For androgenic alopecia (pattern hair loss), Alzheimer disease, and atopic dermatitis (eczema), the evidence we have is insufficient to rate it one way or the other.

We hold no effectiveness data for Sphaeranthus indicus.

The evidence, ingredient by ingredient Mangosteen

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Mangosteen extract is generally considered safe as a food, though long-term safety of concentrated supplements hasn't been well studied. In trials using up to 560 mg daily, a small number of participants reported mild tiredness, headache, dizziness, malaise, and gastrointestinal symptoms including nausea, vomiting, constipation, diarrhea, and abdominal discomfort; dry throat and flu-like symptoms were also noted, though it isn't clear these were caused by mangosteen.

There isn't enough safety information to know whether mangosteen is safe in pregnancy or while breastfeeding — the data advises against using supplement amounts during pregnancy and lactation.

Side effects, ingredient by ingredient Mangosteen

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Mangosteen.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 125 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your doctor or pharmacist before taking FitTrim if you use blood thinners (anticoagulants or antiplatelet drugs) — mangosteen may raise your bleeding risk. Also flag donepezil (Aricept) if you take it, since mangosteen might boost its effects.

No interactions are documented for Sphaeranthus indicus, the other active ingredient.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

FitTrim may be worth considering if you're interested in gum health and have no concerns with its ingredient profile. If you take blood thinners or donepezil, you'll want to check with your doctor or pharmacist before starting it.

The same goes if you're pregnant, breastfeeding, or taking any prescription medication — talk it over with your own healthcare provider to make sure it's right for you.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Mar 24, 2017.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about FitTrim, straight from the product label.

Brand Genesis Today
Barcode (UPC) 812711016955
Net contents 60 Vegetarian Capsule(s)
Market status On market
Date entered into DSLD Mar 24, 2017
DSLD ID 71617
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegetarian, Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for FitTrim by Genesis Today, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
60
UPC/BARCODE
812711016955
IngredientAmount% DV
FitTrim Cardiaslim Blend400 mg--
Sphaeranthus indicus (flower heads) extract0 NP--
Garcinia mangostana (fruit rind) extract0 NP--

Other ingredients: Vegetarian Capsule, Microcrystalline Cellulose, Magnesium Stearate, Silicon Dioxide, Rice hull concentrate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Patented and clinically studied Support your diet goals with FitTrim featuring CardiaSlim.

FitTrim with CardiaSlim

CardiaSlim

General Statements

Supported by three randomized, double-blinded, placebo-controlled studies, CardiaSlim is a naturally derived, patented ingredient show to synergistically support both weight management and cardiovascular health.

Synergistic diet support

Weight management Clinically studied ingredient Cardiovascular health

Austin based

Based on 3 clinical trials with a 2,000 calorie diet and moderate exercise.

Formulation

Vegetarian and stimulant-free, CardiaSlim is protected by U.S. patents 20110280951, EP2391374 and WO2010100653.

Vegetarian and stimulant-free, CardiaSlim is protected by U.S. patents 20110280951, EP2391374 and WO2010100653.

Suggested/Recommended/Usage/Directions

Directions: As a dietary supplement, take one (1) capsule two (2) times per day 30 minutes before meals with a full glass of water or as recommended by your healthcare provider.

Precautions

Do not use if seal around cap is broken.

Keep out of reach of children.

Storage

Store in a cool, dry place.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

FDA Statement of Identity

Dietary Supplement

Brand IP Statement(s)

CardiaSlim brand proprietary blend of two plant extracts is a registered trademark of Laila Nutraceuticals and InterHealth Nutraceuticals, Benicia, CA 94510.

General

PRDL 1-063 LSGT6955-2

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

FitTrim by Genesis Today label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

FitTrim label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in FitTrim by Genesis Today

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

FitTrim Cardiaslim Blend

400 mg per serving

Other (inactive) ingredients: Vegetarian Capsule, Microcrystalline Cellulose, Magnesium Stearate, Silicon Dioxide, Rice hull concentrate. These complete the product’s ingredient list but are not active constituents.

Interaction report

FitTrim by Genesis Today Drug Interactions

Want to check YOUR meds against FitTrim?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
125Drugs
122 Moderate 3 Minor

Ingredients driving the most interactions

Garcinia mangostana (fruit rind) extract 125

Individual Drug Interactions

The ingredients in FitTrim interact with 125 drugs. Click any drug to see the details.

1 of the 2 ingredients in FitTrim interact with drugs. Each result below shows which ingredient is responsible. Garcinia mangostana (fruit rind) extract

Each ingredient & the kinds of drugs it affects

For each ingredient in FitTrim with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Garcinia mangostana (fruit rind) extract2 drug types · 125 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, concomitant use of mangosteen with anticoagulant or antiplatelet drugs may increase the risk of bleeding.
In vitro and animal research shows that gamma-mangostin, a constituent of mangosteen, is a potent and competitive antagonist of the serotonin 2A (5-HT2A) receptor. Antagonism of the 5-HT2A receptor is believed to reduce platelet aggregation.

Likelihood Possible Evidence D
Donepezil (Aricept)

Theoretically, concomitant use of mangosteen with donepezil might increase the effects of donepezil.
Animal research shows that concomitant use of an aqueous extract of mangosteen pericarp with donepezil increases brain concentrations of donepezil at 4 hours by 64% without associated effects on systemic exposure.

Likelihood Possible Evidence D
Garcinia mangostana (fruit rind) extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for FitTrim, from the product label.

Genesis Today

See all Genesis Today products
Name
Genesis Today, Inc.
City
Austin
State
TX
ZipCode
78744
Phone Number
(800) 916-6642
Web Address
GenesisToday.com
Pharmacist Counseling Corner

FitTrim by Genesis Today: Common Questions

Does FitTrim by Genesis Today interact with any medications?
Yes. Based on its ingredients, FitTrim has a known interaction with 125 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
FitTrim contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take FitTrim if I'm pregnant or breastfeeding?
There isn't enough safety data to know either way. The available information suggests avoiding supplement amounts during pregnancy and while breastfeeding. Talk with your doctor or pharmacist about what's right for you before taking it.
Does FitTrim actually work for hair loss?
We don't have enough reliable evidence to say whether mangosteen helps with androgenic alopecia (pattern hair loss). The research on it isn't clear enough to rate it.
What side effects might I notice?
In studies using up to 560 mg daily of mangosteen extract, some participants reported mild fatigue, headache, dizziness, and stomach issues like nausea, constipation, or bloating — though it's unclear whether mangosteen actually caused them. It's not known if FitTrim will cause these at the dose in this product.
Is there anything else in FitTrim besides the active ingredients?
Yes — the capsule itself and several binders and flow agents (microcrystalline cellulose, magnesium stearate, silicon dioxide, and rice hull concentrate) make up the rest of the tablet. These are typical inactive ingredients that help the supplement hold together and dissolve properly.
What does mangosteen actually do in the body?
Mangosteen extract is possibly effective for periodontitis, an infection of the gums and supporting structures. For other conditions like hair loss, eczema, and Alzheimer disease, we don't have enough evidence to say whether it helps.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

FitTrim label
Go deeper

The Full Monographs Behind FitTrim’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Mangosteen

Interacts with 125 drugs

Mangosteen is a tropical fruit whose rind is rich in plant compounds called xanthones that act as antioxidants. While it is popular in juices and supplements for inflammation, immune support...

Read the full Mangosteen monograph →
Sources

Sources & How We Checked

FitTrim's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 6 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Mangosteen 6 references
  1. Chairungsrilerd N, Furukawa K, Ohta T, et al. Histaminergic and serotonergic receptor blocking substances from the medicinal plant Garcinia mangostana. Planta Med 1996;62:471-2.
  2. Wong LP, Klemmer PJ. Severe lactic acidosis associated with juice of the mangosteen fruit Garcinia mangostana. Am J Kidney Dis 2008;51:829-33. PubMed
  3. Furukawa, K., Chairungsrilerd, N., Ohta, T., Nozoe, S., and Ohizumi, Y. [Novel types of receptor antagonists from the medicinal plant Garcinia mangostana]. Nippon Yakurigaku Zasshi 1997;110 Suppl 1:153P-158P. PubMed
  4. Chairungsrilerd, N., Furukawa, K., Tadano, T., Kisara, K., and Ohizumi, Y. Effect of gamma-mangostin through the inhibition of 5-hydroxy-tryptamine2A receptors in 5-fluoro-alpha-methyltryptamine-induced head-twitch responses of mice. Br J Pharmacol. 1998
  5. Suthammarak W, Numpraphrut P, Charoensakdi R, et al. Antioxidant-enhancing property of the polar fraction of mangosteen pericarp extract and evaluation of its safety in humans. Oxid Med Cell Longev 2016;2016:1293036. PubMed
  6. Bae M, Han SY, Kim ES, et al. Effect of Water Extract of Mangosteen Pericarp on Donepezil Pharmacokinetics in Mice. Molecules 2021;26(17):5246. PubMed

See these in context on the Mangosteen monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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