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Dietary supplement

Flaxseed Oil 1250 mg Ingredients & Drug Interactions

by Solgar

Flaxseed Oil 1250 mg label
See full label image
Softgel Capsule Category: Fat/fatty Acid
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 30, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Flaxseed Oil 1250 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Flaxseed Oil 1250 mg is a dietary supplement by Solgar with 1 active ingredient. Its ingredients are commonly taken for source of omega-3 (ala) fatty acids, heart and cholesterol health, dry skin and inflammation.Based on those ingredients, 379 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are organic Flaxseed Oil. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Flaxseed Oil 1250 mg by Solgar

Ask about any prescription or over-the-counter medication and we check it for interactions with Flaxseed Oil 1250 mg by Solgar — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Flaxseed Oil 1250 mg by Solgar

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 30, 2026

What’s inside

Partial disclosure
Ingredient Transparency · database check
Partial

Most active ingredients list an amount, but at least one is hidden in a blend or missing.

Why this rating?
  • The label discloses an exact amount for 6 of its 7 active ingredients.
  • “organic Flaxseed Oil” is listed as a grouped ingredient — the label gives one combined amount (2,500 mg) without saying how much of each component you get.

Solgar Flaxseed Oil 1250 mg is a softgel capsule containing 7 active ingredients: organic flaxseed oil and several fatty acids including oleic acid, linoleic acid, alpha-linolenic acid, palmitic acid, stearic acid, polyunsaturated fat, and other fatty acids. The product also contains two inactive ingredients — gelatin and vegetable glycerin — which serve as the capsule material and binder.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: Omega-3 essential fatty acid source.
  • We looked for evidence on: Atherosclerosis, Cardiovascular disease (CVD), Coronary heart disease (CHD), Hypercholesterolemia, Hyperlipidemia, Hypertension — and 4 related terms.
  • The strongest evidence on file: Oleic Acid is rated "Possibly Effective" for Coronary heart disease (CHD) (Natural Medicines).
  • Also on file: Oleic Acid is rated "Possibly Effective" for Hypercholesterolemia.
  • Also on file: Oleic Acid is rated "Insufficient Reliable Evidence To Rate" for Hypertension, Stroke.

The evidence we hold shows oleic acid (one of this product's components) is possibly effective for high cholesterol (hypercholesterolemia) and heart disease risk (coronary heart disease). For the other fatty acids in this product, we don't have effectiveness ratings on file.

Talk with your doctor or pharmacist about whether flaxseed oil fits your health goals.

The evidence, ingredient by ingredient Flaxseed Oil Oleic Acid

How safe is it?

Some data gaps
Safety Information · database check
Some gaps

Safety data exists for these ingredients, but with some important gaps.

Why this rating?
  • We hold adverse-effect (side-effect) data for 0 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Oleic acid is generally recognized as safe in the amounts found in everyday foods like olive oil. However, concentrated supplement doses of oleic acid haven't been well studied, so caution applies if you're pregnant or breastfeeding — there isn't enough data to know either way.

If you're pregnant, planning pregnancy, or nursing, discuss this product with your doctor or pharmacist for personalized advice.

Side effects, ingredient by ingredient Flaxseed Oil Oleic Acid

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Oleic Acid.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 86 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, check with your doctor or pharmacist if you take antidiabetes drugs (blood sugar medications). The oleic acid in this flaxseed oil may increase how strongly these medications work, potentially lowering your blood sugar more than intended.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glancePartially disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and some safety-information gaps remain.

Solgar Flaxseed Oil may be worth considering if you're interested in heart and cholesterol support, since oleic acid shows promise in those areas. If you take any blood sugar medication, you'll need to check with your doctor or pharmacist first — the oleic acid here could strengthen that drug's effect.

Always run your exact medications through the interaction checker on this page before you start.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 7 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Apr 25, 2019.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Flaxseed Oil 1250 mg, straight from the product label.

Brand Solgar
Barcode (UPC) 033984010703
Net contents 100 Softgel(s)
Market status On market
Date entered into DSLD Apr 25, 2019
DSLD ID 201143
Product type Fat/fatty Acid
Supplement form Softgel Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Flaxseed Oil 1250 mg by Solgar, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Softgel(s)
Maximum serving Sizes:
2 Softgel(s)
Servings per container
50
UPC/BARCODE
033984010703
IngredientAmount% DV
Calories25 Calorie(s)--
Stearic Acid50 mg--
Polyunsaturated Fat2 Gram(s)--
Total Fat2.5 Gram(s)3%
Linoleic Acid275 mg--
Oleic Acid275 mg--
Alpha-Linolenic Acid1125 mg--
Palmitic Acid75 mg--
Other Fatty Acids0 NP--
organic Flaxseed Oil2500 mg--

Other ingredients: Gelatin, Vegetable Glycerin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Flaxseed Oil is one of the premium sources of Alpha-Linolenic Acid (Omega-3), an essential fatty acid that can’t be made by the body and must be obtained from diet. The oil is derived from the seeds of the Flax plant (Linum usitatissimum), one of the most concentrated vegetarian plant sources of Omega-3 fatty acids found in nature. Omega-3 Alpha-Linolenic Acid from Flaxseed Oil helps to support cardiovascular and skin health. This formulation offers premium, organic Flaxseed Oil, cold pressed without the use of chemical solvents.

Cold pressed Omega 3 EFA

Formulation

The oil is derived from the seeds of the Flax plant (Linum usitatissimum), one of the most concentrated vegetarian plant sources of Omega-3 fatty acids found in nature.

This formulation offers premium, organic Flaxseed Oil, cold pressed without the use of chemical solvents.

Non-GMO Gluten, wheat & dairy free

Free Of: Gluten, wheat, dairy, soy, yeast, sugar, sodium, artificial flavor, sweetener, preservatives and color.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Brand IP Statement(s)

2017 Solgar, Inc.

General

SOLGB16103 04D

General Statements

Since 1947

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Suggested Use: As a dietary supplement for adults, take two (2) softgels four times daily, preferably with meals or as directed by a healthcare practitioner.

Precautions

If you are pregnant, nursing, taking any medications or have any medical condition, please consult your healthcare practitioner before taking any dietary supplement.

Discontinue use and consult your healthcare practitioner if any adverse reactions occur.

Keep out of reach of children.

Do not use if outer bottle seal is missing or damaged.

Storage

Store at room temperature.

Refrigerate after opening.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Flaxseed Oil 1250 mg by Solgar label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Flaxseed Oil 1250 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Flaxseed Oil 1250 mg by Solgar

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 Softgel(s) Dosage formSoftgel Capsule Servings per container50 Amounts shown are per serving.

Organic Flaxseed Oil

Interacts with
293 drugs
2500 mg per serving

Flaxseed oil is a plant-based source of the omega-3 fatty acid ALA, which the body can partly convert to the omega-3s found in fish oil. It may help s...

Organic Flaxseed Oil monograph & interactions
  • › Stearic Acid
  • › Linoleic Acid
  • › Oleic Acid
  • › Alpha-Linolenic Acid
  • › Palmitic Acid
  • › Other Fatty Acids

Other (inactive) ingredients: Gelatin, Vegetable Glycerin. These complete the product’s ingredient list but are not active constituents.

Interaction report

Flaxseed Oil 1250 mg by Solgar Drug Interactions

Want to check YOUR meds against Flaxseed Oil 1250 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
379Drugs
379 Moderate

Ingredients driving the most interactions

organic Flaxseed Oil 293

Individual Drug Interactions

The ingredients in Flaxseed Oil 1250 mg interact with 379 drugs. Click any drug to see the details.

1 of the 1 ingredient in Flaxseed Oil 1250 mg interact with drugs. Each result below shows which ingredient is responsible. organic Flaxseed Oil

Each ingredient & the kinds of drugs it affects

For each ingredient in Flaxseed Oil 1250 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

organic Flaxseed Oil3 drug types · 293 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, using flaxseed oil in combination with anticoagulant or antiplatelet drugs might have additive effects and increase the risk of bleeding.
Small clinical studies show that consuming flaxseed oil might decrease platelet aggregation and increase bleeding time.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, combining flaxseed oil with other antihypertensive drugs might have additive effects and increase the risk of hypotension.
Some clinical evidence suggests that long-term consumption of flaxseed oil can modestly lower systolic and diastolic blood pressure, while other clinical research shows no effect.

Likelihood Possible Evidence D
Ezetimibe (Zetia)

Concomitant use of flaxseed oil and ezetimibe reduces the absorption of alpha-linolenic acid from flaxseed oil.
In one clinical study, concomitant consumption of ezetimibe 10 mg daily with flaxseed oil 2 grams providing 1 gram of alpha-linolenic acid daily blocked the absorption of alpha-linolenic acid, resulting in an overall reduction in alpha-linolenic plasma levels from baseline.

Likelihood Probable Evidence B
organic Flaxseed Oil full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Flaxseed Oil 1250 mg, from the product label.

Solgar

See all Solgar products
Name
Solgar, Inc.
Street Address
500 Willow Tree Road
City
Leonia
State
NJ
ZipCode
07605
Phone Number
1-877-765-4274
Web Address
www.solgar.com
Pharmacist Counseling Corner

Flaxseed Oil 1250 mg by Solgar: Common Questions

Does Flaxseed Oil 1250 mg by Solgar interact with any medications?
Yes. Based on its ingredients, Flaxseed Oil 1250 mg has a known interaction with 379 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Flaxseed Oil 1250 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does this flaxseed oil actually lower cholesterol or help my heart?
The oleic acid in this product is possibly effective for high cholesterol and heart disease risk, based on the evidence we hold. That said, 'possibly effective' means the research is promising but not ironclad — talk with your doctor about how this fits into your overall heart health plan.
Is it safe to take if I'm pregnant or breastfeeding?
There isn't enough safety data on concentrated oleic acid supplements in pregnancy and breastfeeding to say either way. Food amounts are fine, but supplement-level doses haven't been well studied. Talk with your doctor or pharmacist before taking this if you're pregnant, planning pregnancy, or nursing.
What's in this besides the flaxseed oil?
The product contains seven active fatty acid components from flaxseed oil, plus gelatin and vegetable glycerin as inactive capsule materials. There are no extra fillers beyond that.
Can I take this with my blood sugar medication?
The oleic acid in this product may make your blood sugar medication work stronger, which could lower your blood sugar more than intended. Check with your doctor or pharmacist before starting — they'll need to know which medication you take and may want to monitor your blood sugar more closely.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Flaxseed Oil 1250 mg is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Flaxseed Oil 1250 mg label
Go deeper

The Full Monographs Behind Flaxseed Oil 1250 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Flaxseed Oil

Interacts with 293 drugs

Flaxseed oil is a plant-based source of the omega-3 fatty acid ALA, which the body can partly convert to the omega-3s found in fish oil. It may help support heart health and provide healthy...

Read the full Flaxseed Oil monograph → Herb & supplement monograph

Oleic Acid

Interacts with 86 drugs

Oleic acid is a heart-healthy monounsaturated fat found mainly in olive oil, canola oil, avocados, and nuts. As part of a Mediterranean-style diet, it is widely viewed as a healthier replace...

Read the full Oleic Acid monograph →
Sources

Sources & How We Checked

Flaxseed Oil 1250 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 22 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Oleic Acid 1 reference
  1. Madigan C, Ryan M, Owens D, et al. Dietary unsaturated fatty acids in type 2 diabetes: higher levels of postprandial lipoprotein on a linoleic acid-rich sunflower oil diet compared with an oleic acid-rich olive oil diet. Diabetes Care 2000;23:1472-7. PubMed

See these in context on the Oleic Acid monograph →

Flaxseed Oil 21 references
  1. Kolonel LN, Nomura AM, Cooney RV. Dietary fat and prostate cancer: current status. J Natl Cancer Inst 1999;91:414-28. PubMed
  2. Ramon JM, Bou R, Romea S, et al. Dietary fat intake and prostate cancer risk: a case-control study in Spain. Cancer Causes Control 2000;11:679-85. PubMed
  3. Nordstrom DC, Honkanen VE, Nasu Y, et al. Alpha-linolenic acid in the treatment of rheumatoid arthritis. A double-blind, placebo-controlled and randomized study: flaxseed vs. safflower seed. Rheumatol Int 1995;14:231-4. PubMed
  4. De Stefani E, Deneo-Pellegrini H, Boffetta P, et al. Alpha-linolenic acid and risk of prostate cancer: a case-control study in Uruguay. Cancer Epidemiol Biomarkers Prev 2000;9:335-8.
  5. Giovannucci E, Rimm EB, Colditz GA, et al. A prospective study of dietary fat and risk of prostate cancer. J Natl Cancer Inst 1993;85:1571-9. PubMed
  6. Bloedon LT, Szapary PO. Flaxseed and cardiovascular risk. Nutr Rev 2004;62:18-27. DOI
  7. Laaksonen DE, Laukkanen JA, Niskanen L, et al. Serum linoleic and total polyunsaturated fatty acids in relation to prostate and other cancers: a population-based cohort study. Int J Cancer 2004;111:444-50.. PubMed
  8. Brouwer IA, Katan MB, Zock PL. Dietary alpha-linolenic acid is associated with reduced risk of fatal coronary heart disease, but increased prostate cancer risk: a meta-analysis. J Nutr 2004;134:919-22.
  9. Paschos GK, Magkos F, Panagiotakos DB, et al. Dietary supplementation with flaxseed oil lowers blood pressure in dyslipidaemic patients. Eur J Clin Nutr 2007;61:1201-6. PubMed
  10. Harper CR, Edwards MC, Jacobson TA. Flaxseed oil supplementation does not affect plasma lipoprotein concentration or particle size in human subjects. J Nutr 2006;136:2844-8. PubMed
  11. University of Montreal. Pregnant Women Consuming Flaxseed Oil Have High Risk Of Premature Birth.ScienceDaily, October 29, 2008. Available at: www.sciencedaily.com/releases/2008/10/081027140817.htm (Accessed May 14, 2009).
  12. Allman, M. A., Pena, M. M., and Pang, D. Supplementation with flaxseed oil versus sunflowerseed oil in healthy young men consuming a low fat diet: effects on platelet composition and function. Eur.J Clin.Nutr. 1995;49(3):169-178.
  13. Ursoniu S, Sahebkar A, Andrica F, Serban C, Banach M; Lipid and Blood Pressure Meta-analysis Collaboration Group. Effects of flaxseed supplements on blood pressure: a systematic review and meta-analysis of controlled clinical trial. Clin Nutr. 2016 Jun;3 PubMed
  14. Taghizadeh M, Jamilian M, Mazloomi M, Sanami M, Asemi Z. A randomized-controlled clinical trial investigating the effect of omega-3 fatty acids on vitamin E co-supplementation on markers of insulin metabolism and lipid profiles in gestational diabetes. J
  15. Blackwood DP, LaVallee RK, Al Busaidi A, Jassal DS, Pierce GN. A randomized trial of the effects of ezetimibe on the absorption of omega-3 fatty acids in cardiac disease patients: a pilot study. Clin Nutr ESPEN. 2015 Oct;10(5):e155-e159. PubMed
  16. Morshedzadeh N, Shahrokh S, Aghdaei HA, et al. Effects of flaxseed and flaxseed oil supplement on serum levels of inflammatory markers, metabolic parameters and severity of disease in patients with ulcerative colitis. Complement Ther Med. 2019;46:36-43. PubMed
  17. Downie LE, Hom MM, Berdy GJ, et al. An artificial tear containing flaxseed oil for treating dry eye disease: A randomized controlled trial. Ocul Surf. 2020;18(1):148-157. PubMed
  18. Saleh-Ghadimi S, Kheirouri S, Golmohammadi A, Moludi J, Jafari-Vayghan H, Alizadeh M. Effect of flaxseed oil supplementation on anthropometric and metabolic indices in patients with coronary artery disease: A double-blinded randomized controlled trial. J PubMed
  19. Jamilian M, Tabassi Z, Reiner Z, et al. The effects of n-3 fatty acids from flaxseed oil on genetic and metabolic profiles in patients with gestational diabetes mellitus: a randomised, double-blind, placebo-controlled trial. Br J Nutr. 2020;123(7):792-799
  20. Li L, Li H, Gao Y, Vafaei S, Zhang X, Yang M. Effect of flaxseed supplementation on blood pressure: a systematic review, and dose-response meta-analysis of randomized clinical trials. Food Funct 2023;14(2):675-690. PubMed
  21. Mahmudiono T, Jasim SA, Karim YS, et al. The effect of flaxseed oil consumption on blood pressure among patients with metabolic syndrome and related disorders: A systematic review and meta-analysis of randomized clinical trials. Phytother Res 2022;36(10):

See these in context on the Flaxseed Oil monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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