Interactions on record — worth a quick check against your medications. Based on 1 of 4 ingredients. Check your meds →
Dietary supplement

Florajen4Kids Ingredients & Drug Interactions

by American Lifeline

Florajen4Kids label
See full label image
Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Florajen4Kids against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Florajen4Kids is a dietary supplement by American Lifeline with 4 active ingredients. Its ingredients are commonly taken for digestive health and balance, diarrhea (including antibiotic-related), vaginal yeast and bacterial infections.Based on those ingredients, 182 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Lactobacillus acidophilus NCFM. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Florajen4Kids by American Lifeline

Ask about any prescription or over-the-counter medication and we check it for interactions with Florajen4Kids by American Lifeline — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Florajen4Kids by American Lifeline

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 30, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 4 of its 4 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

Florajen4Kids contains 4 active probiotic ingredients: two strains of Bifidobacterium (lactis HN019 and Bi-07), one strain of Lactobacillus acidophilus (NCFM), and one strain of Lactobacillus rhamnosus (HN001). These are live beneficial bacteria designed to support digestive health.

The capsules also contain vegetarian capsule material and rice dextrin as inactive ingredients.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: probiotic support for children's digestive health.
  • We looked for evidence on: Antibiotic-associated diarrhea, Colic, Constipation, Irritable bowel syndrome (IBS), Lactose intolerance, Rotaviral diarrhea — and 4 related terms.
  • The strongest evidence on file: Lactobacillus Acidophilus is rated "Possibly Effective" for Antibiotic-associated diarrhea (Natural Medicines).
  • Also on file: Lactobacillus Acidophilus is rated "Possibly Effective" for Irritable bowel syndrome (IBS).
  • Also on file: Lactobacillus Acidophilus is rated "Insufficient Reliable Evidence To Rate" for Constipation, Lactose intolerance, Rotaviral diarrhea, Travelers' diarrhea, and more.

The evidence we hold covers only Lactobacillus acidophilus from this product. It's rated possibly effective for irritable bowel syndrome (IBS), antibiotic-associated diarrhea, Helicobacter pylori infection, and bacterial vaginosis.

It's rated possibly ineffective for atopic disease (like eczema and allergies), and the evidence is insufficient to rate it for acute respiratory distress syndrome (ARDS). We don't have effectiveness ratings for the other three strains in this product.

The evidence, ingredient by ingredient Lactobacillus Acidophilus

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Lactobacillus acidophilus is generally well tolerated in healthy children and adults. That said, because these are live organisms, there is a small theoretical risk of infection in certain patients—though most reported cases appear linked to translocation of bacteria from other body sites rather than the probiotic itself.

When taken orally in combination with other probiotics, some people report mild gastrointestinal side effects like bloating, gas, stomach discomfort, or loose stool, but these are uncommon. One trial reported rare skin rash and itching, though it's unclear whether those were caused by L. acidophilus or another ingredient.

The safety data for L. acidophilus in pregnancy is rated possibly safe. We don't have safety information on file for the other three strains.

Side effects, ingredient by ingredient Lactobacillus Acidophilus

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Lactobacillus Acidophilus.
  • The most serious interaction on file is rated Moderate.
  • For scale: 182 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If your child is taking antibiotic drugs, separate the timing—don't give them together. Antibiotics can kill the live probiotic organisms and reduce its effectiveness.

Talk to your pediatrician or pharmacist about the best spacing for your child's specific antibiotic.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Florajen4Kids is a four-strain probiotic aimed at children's digestive health, with the most evidence for Lactobacillus acidophilus in conditions like IBS and antibiotic-related diarrhea. The main caution is spacing doses away from antibiotics so the antibiotic doesn't kill off the live bacteria.

Because live organisms carry a small theoretical infection risk and safety data for kids are limited, check with your pediatrician or pharmacist before starting, especially if your child has a weakened immune system or is on antibiotics.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Dec 29, 2014.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Florajen4Kids, straight from the product label.

Brand American Lifeline
Barcode (UPC) 739423880486
Net contents 30 Capsule(s)
Market status On market
Date entered into DSLD Dec 29, 2014
DSLD ID 34126
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegetarian, Children (All), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Florajen4Kids by American Lifeline, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
30
UPC/BARCODE
739423880486
IngredientAmount% DV
Lactobacillus rhamnosus HN001500000000 NP--
Bifidobacterium lactis HN0191000000000 NP--
Lactobacillus acidophilus NCFM1000000000 NP--
Bifidobacterium lactis Bi-073500000000 NP--

Other ingredients: Vegetarian Capsules, Rice Dextrin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity

Probiotic Dietary Supplement

General Statements

Safe and Effective Formula For Children of All Ages

Unique Multiculture Formula for Children of All Ages* Florajen4Kids contain four carefully selected strains of beneficial flora that are safe and effective.

With Essential Bifido Culture

*Restores floral balance, essential to GI and vaginal health, often disrupted by antibiotics.

Floreajen4Kids provides this complex and critical role through an exclusive mix of two strains of these important Bifido cultures.

Money Back Guarantee We will refund your money if you are not completely satisfied with the effectiveness of Florajen4Kids.

For Potent Probiotic Benefits and Antibiotic Side Effects*

Maintains healthy, comfortable balance of the body's flora

Formula

6 Billion Live Cultures Per Capsule

Lactobacillus acidophilus, the same strain used by U.S. yogurt companies since 1973, and Lactobacillus rhamnosus are both helpful in maintaining the equilibrium of friendly flora, especially when antibiotics disrupt that critical balance. Most important and absolutely essential to the development of healthy immune and digestive function in children are Bifidobacterium species.

Formulation

Gluten-Fee

Gluten-free, Vegetarian, Dairy-free Does not contain yeast, soy, eggs, wheat, gluten, coloring, preservatives or dairy.

Vegetarian

Dairy-free

Brand IP Statement(s)

Culture You Can Count On(TM)

(c)2011 American Lifeline, Inc. All rights reserved.

Precautions

*For children under 6 months old, it's always best to consult a healthcare professional before use.

Tamper evident. Do not use if safety seal on bottle is broken.

Suggested/Recommended/Usage/Directions

Usage: Take 1 capsule daily unless a higher dosage is recommended by your healthcare professional. Swallow or pull open the vegetarian capsule and sprinkle the tasteless powder on cold food or drinks.

Storage

Storage: Refrigerate for maximum potency. Can be stored at room temperature for up to two weeks while traveling and still maintain effectiveness.

FDA Disclaimer Statement

Statements on this package have not been evaluated by the Food and Drug Administration. This product is not medicinal and is not intended to diagnose, treat, cure or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Florajen4Kids by American Lifeline label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Florajen4Kids label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Florajen4Kids by American Lifeline

These are the 4 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Lactobacillus rhamnosus HN001

500000000 NP per serving

Bifidobacterium lactis HN019

1000000000 NP per serving

Lactobacillus acidophilus NCFM

Interacts with
182 drugs
1000000000 NP per serving

Lactobacillus acidophilus is a 'friendly' bacterium used as a probiotic to support gut and vaginal health. It is generally well tolerated in healthy p...

Lactobacillus acidophilus NCFM monograph & interactions

Bifidobacterium lactis Bi-07

3500000000 NP per serving

Other (inactive) ingredients: Vegetarian Capsules, Rice Dextrin. These complete the product’s ingredient list but are not active constituents.

Interaction report

Florajen4Kids by American Lifeline Drug Interactions

Want to check YOUR meds against Florajen4Kids?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
182Drugs
182 Moderate

Ingredients driving the most interactions

Lactobacillus acidophilus NCFM 182

Individual Drug Interactions

The ingredients in Florajen4Kids interact with 182 drugs. Click any drug to see the details.

1 of the 4 ingredients in Florajen4Kids interact with drugs. Each result below shows which ingredient is responsible. Lactobacillus acidophilus NCFM

Each ingredient & the kinds of drugs it affects

For each ingredient in Florajen4Kids with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Lactobacillus acidophilus NCFM1 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking Lactobacillus acidophilus with antibiotic drugs might decrease the effectiveness of L. acidophilus.
L. acidophilus preparations usually contain live and active organisms. Therefore, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and L. acidophilus preparations by at least two hours.

Likelihood Probable Evidence D
Lactobacillus acidophilus NCFM full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Florajen4Kids, from the product label.

American Lifeline

See all American Lifeline products
Name
American Lifeline, Inc.
Street Address
138 First Street
City
Baraboo
State
Wisconsin
ZipCode
53913
Pharmacist Counseling Corner

Florajen4Kids by American Lifeline: Common Questions

Does Florajen4Kids by American Lifeline interact with any medications?
Yes. Based on its ingredients, Florajen4Kids has a known interaction with 182 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Florajen4Kids contains 4 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is Florajen4Kids safe for my child to take?
Lactobacillus acidophilus in this product is generally well tolerated in healthy children. However, because it contains live organisms, there is a small theoretical risk of infection in certain patients. Since safety data for kids are limited, check with your pediatrician before starting, especially if your child has a weakened immune system.
My child is on an antibiotic. Can they take this probiotic at the same time?
No—not at the same time. Antibiotics can kill the live bacteria in the probiotic, making it less effective. Separate the doses as much as possible, and ask your pediatrician or pharmacist what timing works best for your child.
What does Lactobacillus acidophilus actually do?
Lactobacillus acidophilus is a beneficial bacteria that may help with irritable bowel syndrome, antibiotic-associated diarrhea, and certain infections. The evidence is solid enough to rate it possibly effective for those uses, though results vary.
Are there any common side effects?
Mild gastrointestinal side effects like bloating, gas, or loose stool can happen when probiotics are taken with other beneficial bacteria, but they're uncommon. One trial reported rare rash and itching, though it's unclear what caused them.
Is Florajen4Kids safe during pregnancy or breastfeeding?
The safety data we hold is only for Lactobacillus acidophilus, which is rated possibly safe in pregnancy. We don't have pregnancy or breastfeeding information for the other three strains, and we have no data on safety for nursing mothers. Talk with your obstetrician or midwife before use.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Florajen4Kids label
Go deeper

The Full Monographs Behind Florajen4Kids’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Lactobacillus Acidophilus

Interacts with 182 drugs

Lactobacillus acidophilus is a 'friendly' bacterium used as a probiotic to support gut and vaginal health. It is generally well tolerated in healthy people, and there is reasonable evidence...

Read the full Lactobacillus Acidophilus monograph →
Sources

Sources & How We Checked

Florajen4Kids's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 15 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lactobacillus Acidophilus 15 references
  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  2. Begtrup LM, de Muckadell OB, Kjeldsen J, Christensen RD, Jarbøl DE. Long-term treatment with probiotics in primary care patients with irritable bowel syndrome--a randomised, double-blind, placebo controlled trial. Scand J Gastroenterol 2013;48(10):1127-35 PubMed
  3. Chatterjee S, Kar P, Das T, Ray S, Gangulyt S, Rajendiran C, Mitra M. Randomised placebo-controlled double blind multicentric trial on efficacy and safety of Lactobacillus acidophilus LA-5 and Bifidobacterium BB-12 for prevention of antibiotic-associated
  4. Shavakhi A, Tabesh E, Yaghoutkar A, Hashemi H, Tabesh F, Khodadoostan M,Minakari M, Shavakhi S, Gholamrezaei A. The effects of multistrain probiotic compound on bismuth-containing quadruple therapy for Helicobacter pylori infection: a randomized placebo-c
  5. Karamali M, Dadkhah F, Sadrkhanlou M, et al. Effects of probiotic supplementation on glycaemic control and lipid profiles in gestational diabetes: a randomized, double-blind, placebo-controlled trial. Diabetes Metab 2016;42(4):234-41. PubMed
  6. Badehnoosh B, Karamali M, Zarrati M, et al. The effects of probiotic supplementation on biomarkers of inflammation, oxidative stress and pregnancy outcomes in gestational diabetes. J Matern Fetal Neonatal Med. 2018 May;31(9):1128-1136.
  7. Kumar S, Kumar R, Rohilla L, Jacob N, Yadav J, Sachdeva N. A high potency multi-strain probiotic improves glycemic control in children with new-onset type 1 diabetes mellitus: A randomized, double-blind, and placebo-controlled pilot study. Pediatr Diabete
  8. Shahriari A, Karimi E, Shahriari M, Aslani N, Khooshideh M, Arab A. The effect of probiotic supplementation on the risk of gestational diabetes mellitus among high-risk pregnant women: A parallel double-blind, randomized, placebo-controlled clinical trial PubMed
  9. Xiao SD, Zhang DZ, Lu H, et al. Multicenter, randomized, controlled trial of heat-killed Lactobacillus acidophilus LB in patients with chronic diarrhea. Adv Ther. 2003;20(5):253-60.
  10. Rossi F, Amadoro C, Gasperi M, Colavita G. Lactobacilli infection case reports in the last three years and safety implications. Nutrients. 2022;14(6):1178. PubMed
  11. Ozer M, Goksu SY, Shahverdiani A, Mustafa M. Lactobacillus acidophilus-induced endocarditis and associated splenic abscess. Case Rep Infect Dis 2020;2020:1382709.
  12. Sadrin S, Sennoune S, Gout B, et al. A 2-strain mixture of Lactobacillus acidophilus in the treatment of irritable bowel syndrome: A placebo-controlled randomized clinical trial. Dig Liver Dis 2020;52(5):534-540. PubMed
  13. Stoffer JN, Slingsby TJ, Giuliari GP. Lactobacillus acidophilus endophthalmitis after intravitreal bevacizumab injection requiring intraocular lens explantation. Can J Ophthalmol 2022;57(1):e21-e22. PubMed
  14. Cukovic-Cavka S, Likic R, Francetic I, Rustemovic N, Opacic M, Vucelic B. Lactobacillus acidophilus as a cause of liver abscess in a NOD2/CARD15-positive patient with Crohn's disease. Digestion 2006;73(2-3):107-10.
  15. Hui J, Ren Y, Wang Y, Han Q. Lactobacillus acidophilus endophthalmitis postcataract operation: A case report with a literature review. Ocul Immunol Inflamm 2023.

See these in context on the Lactobacillus Acidophilus monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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