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Dietary supplement

FloraSure Probiotic 20 Billion CFU Ingredients & Drug Interactions

by Terry Naturally

FloraSure Probiotic 20 Billion CFU label
See full label image
Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking FloraSure Probiotic 20 Billion CFU against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

FloraSure Probiotic 20 Billion CFU is a dietary supplement by Terry Naturally with 3 active ingredients. Its ingredients are commonly taken for digestive health and regularity, diarrhea (including antibiotic-related), irritable bowel syndrome (ibs) symptoms.Based on those ingredients, 182 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Bifidobacterium bifidum. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against FloraSure Probiotic 20 Billion CFU by Terry Naturally

Ask about any prescription or over-the-counter medication and we check it for interactions with FloraSure Probiotic 20 Billion CFU by Terry Naturally — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of FloraSure Probiotic 20 Billion CFU by Terry Naturally

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 3 active ingredients.
  • “FloraSure Probiotic Blend” is a proprietary blend — the label gives one combined amount (101 mg) without saying how much of each component you get.

FloraSure Probiotic contains three active ingredients: Lactobacillus plantarum, Bifidobacterium bifidum, and Lactobacillus rhamnosus — all live, beneficial bacteria (probiotics) that support gut health. Together they deliver 20 billion colony-forming units (CFU) per capsule.

The product also contains inactive ingredients including rice maltodextrin, hydroxypropyl methylcellulose (a capsule binder), fructooligosaccharides (a prebiotic fiber that feeds probiotics), magnesium stearate, and silica.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: digestive health and regularity.
  • We looked for evidence on: Antibiotic-associated diarrhea, Constipation, Irritable bowel syndrome (IBS), Colic, Clostridioides difficile infection, Pouchitis — and 4 related terms.
  • The strongest evidence on file: Bifidobacterium Bifidum is rated "Possibly Effective" for Irritable bowel syndrome (IBS) (Natural Medicines).
  • Also on file: Bifidobacterium Bifidum is rated "Insufficient Reliable Evidence To Rate" for Antibiotic-associated diarrhea, Constipation, Radiation-induced diarrhea, Ulcerative colitis, and more.

Bifidobacterium bifidum is possibly effective for irritable bowel syndrome (IBS) and respiratory tract infections based on the evidence we have. For allergic rhinitis (hay fever), generalized anxiety disorder, and Alzheimer disease, the evidence is too limited to say whether it works — more research is needed.

Since we couldn't check the other two bacterial strains in this product, we can't speak to their individual effectiveness ratings.

The evidence, ingredient by ingredient Bifidobacterium Bifidum

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Bifidobacterium bifidum is generally well tolerated in healthy people. Those with weakened immune systems should be cautious before use, and it's wise to check with your doctor or pharmacist first because evidence is still limited.

Bloating and flatulence have been reported with probiotic use overall, though not specifically tied to B. bifidum in the studies we have. One case of vomiting and fever was reported in a child taking B. bifidum with another probiotic strain, but it's unclear whether the probiotics caused it.

Serious infections from Bifidobacterium are extremely rare and haven't been linked to B. bifidum specifically.

Side effects, ingredient by ingredient Bifidobacterium Bifidum

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Bifidobacterium Bifidum.
  • The most serious interaction on file is rated Moderate.
  • For scale: 182 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Antibiotic drugs are the main medication type to double-check before taking this product — they may reduce how well the probiotic works. Since we couldn't check two of the three active ingredients in this product, there may be other medication interactions we don't have data for yet.

Search your medications on this page to be sure.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This probiotic may help with IBS and respiratory infections if Bifidobacterium bifidum is the active ingredient driving the benefit. If you're on an antibiotic, talk to your pharmacist about spacing out the doses.

Those with weakened immune systems should check with their doctor first. Use the interaction checker below for your specific medications.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Mar 25, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about FloraSure Probiotic 20 Billion CFU, straight from the product label.

Brand Terry Naturally
Barcode (UPC) 367703307035
Net contents 30 Capsule(s)
Market status On market
Date entered into DSLD Mar 25, 2025
DSLD ID 325747
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Kosher, Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for FloraSure Probiotic 20 Billion CFU by Terry Naturally, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
30
UPC/BARCODE
367703307035
IngredientAmount% DV
Lactobacillus plantarum0 NP--
Bifidobacterium bifidum0 NP--
Lactobacillus rhamnosus0 NP--
FloraSure Probiotic Blend101 mg--

Other ingredients: Rice Maltodextrin, Hydroxypropyl Methylcellulose, Fructooligosaccharides, Magnesium Stearate, Silica

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Recommendations: 1 capsule daily, with food.

Just one daily

Precautions

If pregnant or nursing, consult a healthcare practitioner before use.

Storage

No refrigeration necessary. 2 years guaranteed shelf life at room temperature. Refrigeration will extend shelf life.

Formulation

FloraSure Probiotic relieves occasional intestinal discomforts and helps keep your digestive system regular. Relieves occasional: Gas bloating, and cramping Irregularity, diarrhea, and constipation

Money-back guarantee

Daily support for healthy digestion

Vegan

No sugar, salt, wheat, gluten, soy, dairy products, artificial coloring, artificial flavoring, or artificial preservatives.

Terry Naturally brand products contain natural and other premium ingredients.

Non GMO Dairy Free

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

FDA Statement of Identity

Dietary Supplement

Formula

OK D (Kosher dairy)

Seals/Symbols

Vegan Lab tested for purity & quality OK D (Kosher dairy)

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

FloraSure Probiotic 20 Billion CFU by Terry Naturally label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

FloraSure Probiotic 20 Billion CFU label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in FloraSure Probiotic 20 Billion CFU by Terry Naturally

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

FloraSure Probiotic Blend

101 mg per serving

Other (inactive) ingredients: Rice Maltodextrin, Hydroxypropyl Methylcellulose, Fructooligosaccharides, Magnesium Stearate, Silica. These complete the product’s ingredient list but are not active constituents.

Interaction report

FloraSure Probiotic 20 Billion CFU by Terry Naturally Drug Interactions

Want to check YOUR meds against FloraSure Probiotic 20 Billion CFU?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
182Drugs
182 Moderate

Ingredients driving the most interactions

Bifidobacterium bifidum 182

Individual Drug Interactions

The ingredients in FloraSure Probiotic 20 Billion CFU interact with 182 drugs. Click any drug to see the details.

1 of the 3 ingredients in FloraSure Probiotic 20 Billion CFU interact with drugs. Each result below shows which ingredient is responsible. Bifidobacterium bifidum

Each ingredient & the kinds of drugs it affects

For each ingredient in FloraSure Probiotic 20 Billion CFU with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Bifidobacterium bifidum1 drug type · 182 drugs

Antibiotic Drugs

Theoretically, taking Bifidobacterium. bifidum with antibiotic drugs might decrease the effectiveness of B. bifidum.
Since B. bifidum preparations usually contain live and active organisms, simultaneously taking antibiotics might kill a significant number of the organisms. Tell patients to separate administration of antibiotics and B. bifidum preparations by at least 2 hours.

Likelihood Probable Evidence D
Bifidobacterium bifidum full monograph & interactions
The maker

Brand information

Manufacturer and brand details for FloraSure Probiotic 20 Billion CFU, from the product label.

Terry Naturally

See all Terry Naturally products
Name
EuroPharma, Inc.
City
Green Bay
State
WI
ZipCode
54311
Phone Number
(866) 807-2731
Web Address
EuroPharmaUSA.com
Pharmacist Counseling Corner

FloraSure Probiotic 20 Billion CFU by Terry Naturally: Common Questions

Does FloraSure Probiotic 20 Billion CFU by Terry Naturally interact with any medications?
Yes. Based on its ingredients, FloraSure Probiotic 20 Billion CFU has a known interaction with 182 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
FloraSure Probiotic 20 Billion CFU contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this probiotic while I'm on an antibiotic?
Theoretically, antibiotics can kill the live bacteria in the probiotic and make it less effective. Your best bet is to space them out — take the antibiotic and probiotic at different times of day. Ask your pharmacist to help you plan the timing.
Will this help my IBS or respiratory infections?
Bifidobacterium bifidum, one of the three bacteria in this product, is possibly effective for both IBS and respiratory tract infections based on available evidence. Results vary from person to person, so give it time and talk to your doctor if you're not seeing improvement.
What are the side effects?
Bloating and flatulence have been reported with probiotics in general, though not specifically from Bifidobacterium bifidum. Most people tolerate it well. One rare case of vomiting and fever was reported in a child, but it's unclear if the probiotic caused it.
Is it safe if I have a weakened immune system?
Those with weakened immune systems should be cautious and check with your doctor before use. The evidence is still limited, so personalized medical advice is important in your case.
What do these bacteria actually do in my gut?
Probiotics are live, beneficial bacteria that support a healthy gut environment. Lactobacillus and Bifidobacterium strains are among the most common types used to promote digestive and immune health.
Are there any fillers or other ingredients in here?
Yes — the capsule contains rice maltodextrin, a binder called hydroxypropyl methylcellulose, fructooligosaccharides (a prebiotic fiber that feeds the probiotics), magnesium stearate, and silica.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if FloraSure Probiotic 20 Billion CFU is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

FloraSure Probiotic 20 Billion CFU label
Go deeper

The Full Monographs Behind FloraSure Probiotic 20 Billion CFU’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Bifidobacterium Bifidum

Interacts with 182 drugs

Bifidobacterium bifidum is a 'friendly' bacteria (probiotic) that naturally lives in the human gut and is taken to support digestion and gut balance. Some evidence suggests probiotics may he...

Read the full Bifidobacterium Bifidum monograph →
Sources

Sources & How We Checked

FloraSure Probiotic 20 Billion CFU's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 7 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Bifidobacterium Bifidum 7 references
  1. Pierce A. The American Pharmaceutical Association Practical Guide to Natural Medicines. New York: The Stonesong Press, 1999:19.
  2. Xiao JZ, Takahashi S, Odamaki T, et al. Antibiotic susceptibility of bifidobacterial strains distributed in the Japanese market. Biosci Biotechnol Biochem. 2010;74(2):336-42. PubMed
  3. Rerksuppaphol S, Rerksuppaphol L. Randomized controlled trial of probiotics to reduce common cold in schoolchildren. Pediatr Int. 2012;54(5):682-7. PubMed
  4. Karamali M, Dadkhah F, Sadrkhanlou M, et al. Effects of probiotic supplementation on glycaemic control and lipid profiles in gestational diabetes: a randomized, double-blind, placebo-controlled trial. Diabetes Metab 2016;42(4):234-41. PubMed
  5. Badehnoosh B, Karamali M, Zarrati M, et al. The effects of probiotic supplementation on biomarkers of inflammation, oxidative stress and pregnancy outcomes in gestational diabetes. J Matern Fetal Neonatal Med. 2018 May;31(9):1128-1136.
  6. Pruccoli G, Silvestro E, Pace Napoleone C, Aidala E, Garazzino S, Scolfaro C. Are probiotics safe? Bifidobacterium bacteremia in a child with severe heart failure. Infez Med. 2019;27(2):175-178.
  7. Esaiassen E, Hjerde E, Cavanagh JP, Simonsen GS, Klingenberg C; Norwegian Study Group on Invasive Bifidobacterial Infections. Bifidobacterium bacteremia: Clinical characteristics and a genomic approach to assess pathogenicity. J Clin Microbiol. 2017;55(7) PubMed

See these in context on the Bifidobacterium Bifidum monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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