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Dietary supplement

Fu Shen Ingredients & Drug Interactions

by Herbal Terra

Fu Shen label
See full label image
Liquid Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Fu Shen against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Fu Shen is a dietary supplement by Herbal Terra with 1 active ingredient. Its ingredients are commonly taken for fluid retention and swelling, digestive complaints, sleep and calming support.Based on those ingredients, 417 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are wildcrafted Fu Shen dried sclerotia with hostwood liquid extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Fu Shen by Herbal Terra

Ask about any prescription or over-the-counter medication and we check it for interactions with Fu Shen by Herbal Terra — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Fu Shen by Herbal Terra

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: poria mushroom sclerotia (the hardened fruiting body of the fungus) extracted into a liquid form. The extract is suspended in menstruum, the liquid carrier that allows it to be taken as drops or added to water.

Poria mushroom has been used in traditional medicine for centuries, particularly in Asian herbal practice, though the scientific evidence behind many of those traditional uses remains limited.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Poria Mushroom product and its label doesn't state a use — see Poria Mushroom's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence for poria mushroom extract isn't established in the data we hold. Our current information shows insufficient reliable evidence to rate it for cancer, chronic fatigue syndrome, dementia, diabetes, diabetic kidney disease, or diarrhea.

If you're considering this product for any of those conditions, talk with your doctor or pharmacist about what the best-supported options are for you.

The evidence, ingredient by ingredient Poria Mushroom

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Poria mushroom extract is generally well tolerated in traditional use, but human safety data are limited. Allergic reactions have been reported rarely, including allergic rhinitis and allergic asthma—watch for signs like rash, itching, sneezing, or wheezing when you first start.

There isn't enough safety information to recommend this product during pregnancy, and no reliable data exist while breastfeeding, so avoidance is advised if you're pregnant or nursing.

Side effects, ingredient by ingredient Poria Mushroom

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Poria Mushroom.
  • The most serious interaction on file is rated Moderate.
  • For scale: 417 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take Fu Shen, double-check if you're using sedatives or CNS depressants (sleeping pills, anxiety medications, muscle relaxants), anticholinergic drugs (certain allergy and bladder medicines), or cholinergic drugs (some medications for memory or myasthenia gravis). All three categories carry a Moderate interaction rating with this product's poria mushroom extract.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Fu Shen is a traditional herbal liquid that may be appealing if you're drawn to mushroom-based preparations, but the evidence for what it actually does is sparse. More important: it can interact with sedatives and several other medication types at a Moderate level.

Check your medications below before taking this, and talk with your pharmacist, especially if you're pregnant, breastfeeding, or taking anything for sleep or nerve function.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Fu Shen, straight from the product label.

Brand Herbal Terra
Barcode (UPC) 7429523595559
Net contents 4 Fluid Ounce(s); 120 mL
Market status On market
Date entered into DSLD Sep 25, 2020
DSLD ID 233813
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Fu Shen by Herbal Terra, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 mL
Maximum serving Sizes:
1 mL
Servings per container
120
UPC/BARCODE
7429523595559
IngredientAmount% DV
wildcrafted Fu Shen dried sclerotia with hostwood liquid extract970 mg--

Other ingredients: Menstruum

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Direction Shake well before use. Adults take up to 30 drops (1 mL, one full squeeze of the dropper bulb) in 3-4 fl. oz of juice or water up to 4 times a day. We recommend to seek expert medical advice before taking this or any other herbal supplements.

FDA Disclaimer Statement

Notice This product has not been evaluated by the FDA and is not intended to diagnose, treat, cure, or prevent any disease.

Formulation

Manufactured in the USA in an FDA registered facility

Sugar free

Dried herb/menstruum ratio: 1:3 Expertly extracted Laboratory tested 330 mg/1 mL Premium product Super concentrated liquid herbal extract

Non GMO

No artificial ingredients, GMO, gluten, color additives, fillers, preservatives or binders. Natural Gluten Free

Precautions

Caution May have contraindications.

Do not use if you are allergic to any ingredients.

Consult a physician before using during pregnancy, if nursing, or if you are on any medications.

Keep out of the reach of children.

Storage

Store in a cool, dry, dark place.

Formula

Poria cocos

FDA Statement of Identity

Herbal Supplement

Seals/Symbols

Made in USA Made in an FDA registered facility Natural Gluten Free

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Fu Shen by Herbal Terra label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Fu Shen label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Fu Shen by Herbal Terra

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 mL Dosage formLiquid Servings per container120 Amounts shown are per serving.

Wildcrafted Fu Shen dried sclerotia with hostwood liquid extract

Interacts with
417 drugs
970 mg per serving

Poria mushroom (Fu Ling) is a fungus long used in Traditional Chinese Medicine, mainly as a mild diuretic and digestive and calming aid. Modern scient...

Wildcrafted Fu Shen dried sclerotia with hostwood liquid extract monograph & interactions

Other (inactive) ingredients: Menstruum. These complete the product’s ingredient list but are not active constituents.

Interaction report

Fu Shen by Herbal Terra Drug Interactions

Want to check YOUR meds against Fu Shen?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
417Drugs
417 Moderate

Ingredients driving the most interactions

wildcrafted Fu Shen dried sclerotia with hostwood liquid extract 417

Individual Drug Interactions

The ingredients in Fu Shen interact with 417 drugs. Click any drug to see the details.

1 of the 1 ingredient in Fu Shen interact with drugs. Each result below shows which ingredient is responsible. wildcrafted Fu Shen dried sclerotia with hostwood liquid extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Fu Shen with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

wildcrafted Fu Shen dried sclerotia with hostwood liquid extract3 drug types · 417 drugs

Anticholinergic Drugs

Theoretically, poria mushroom might decrease the clinical effects of anticholinergic drugs.
In animal research, poria mushroom essential oil reduces acetylcholinesterase activity. This interaction has not been shown in humans.

Likelihood Possible Evidence D
Cholinergic Drugs

Theoretically, poria mushroom might have additive effects when used with cholinergic drugs.
In animal research, poria mushroom essential oil reduces acetylcholinesterase activity. This interaction has not been shown in humans.

Likelihood Possible Evidence D
Cns Depressants

Theoretically, taking poria mushroom extract may enhance the therapeutic and adverse effects of sedatives.
Animal research shows that poria mushroom extract has sedative properties. This interaction has not been shown in humans.

Likelihood Possible Evidence D
wildcrafted Fu Shen dried sclerotia with hostwood liquid extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Fu Shen, from the product label.

Herbal Terra

See all Herbal Terra products
Name
Herbal Terra
Pharmacist Counseling Corner

Fu Shen by Herbal Terra: Common Questions

Does Fu Shen by Herbal Terra interact with any medications?
Yes. Based on its ingredients, Fu Shen has a known interaction with 417 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Fu Shen contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is Fu Shen, and where does it come from?
Fu Shen is a liquid extract of poria mushroom sclerotia—the dense, hardened fruiting body of a fungus used in traditional Asian herbal medicine for centuries. This version is wildcrafted (harvested from nature) and extracted into a liquid form you can take by the drop.
Can I take this while pregnant or breastfeeding?
No, it's best to avoid Fu Shen during pregnancy because there isn't enough safety information. The same goes for breastfeeding—reliable safety data don't exist, so avoidance is recommended. Talk with your doctor or midwife if you're interested in herbal support during these times.
Does poria mushroom really help with fatigue, brain fog, or diabetes?
The evidence isn't established yet. Our data show insufficient reliable evidence to rate poria mushroom for chronic fatigue, dementia, diabetes, or several other conditions. If you're dealing with any of those, your doctor can point you toward options with stronger scientific backing.
Could I have an allergic reaction to this?
Allergic reactions are rare but have been reported, including allergic rhinitis (runny or stuffy nose from allergy) and allergic asthma. If you notice rash, itching, sneezing, or breathing trouble after starting, stop and contact your pharmacist or doctor right away.
Why do I need to check my medications before taking this?
Poria mushroom extract can interact with sedatives, anticholinergic drugs, and cholinergic drugs in ways that boost or dampen their effects. These interactions haven't been tested in humans, but animal research suggests they're possible. Your pharmacist can check whether any of your medications fall into those categories.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Fu Shen is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Fu Shen label
Go deeper

The Full Monographs Behind Fu Shen’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Poria Mushroom

Interacts with 417 drugs

Poria mushroom (Fu Ling) is a fungus long used in Traditional Chinese Medicine, mainly as a mild diuretic and digestive and calming aid. Modern scientific evidence in humans is very limited,...

Read the full Poria Mushroom monograph →
Sources

Sources & How We Checked

Fu Shen's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 3 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Poria Mushroom 3 references
  1. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  2. Kim H, Park I, Park K, Park S, Kim YI, Park BG. The positive effects of Poria cocos extract on quality of sleep in insomnia rat models. Int J Environ Res Public Health 2022;19(11):6629. PubMed
  3. Lv Q, Di X, Bian B, Li K, Guo J. Neuroprotective effects of Poria cocos (Agaricomycetes) essential oil on Aß1-40-induced learning and memory deficit in rats. Int J Med Mushrooms 2022;24(10):73-82.

See these in context on the Poria Mushroom monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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