Fucoxanthin-Slim Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Fucoxanthin-Slim against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Fucoxanthin-Slim is a dietary supplement by Life Extension with 1 active ingredient.Based on those ingredients, 922 medications have a known interaction with it, the most serious rated moderate. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Fucoxanthin-Slim by Life Extension
Ask about any prescription or over-the-counter medication and we check it for interactions with Fucoxanthin-Slim by Life Extension — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
Ask the Pharmacist
A licensed pharmacist will answer your question by email — free, usually within 24 hours.
Got it — thank you!
A licensed pharmacist will answer within 24 hours. Keep an eye on your email (worth checking spam, just in case).
HelloPharmacist Scorecard of Fucoxanthin-Slim by Life Extension
Four independent checks of what is known — a summary of the available information, not a grade of the product itself.
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
The stated purpose hasn't been mapped to our evidence data yet.
Why this rating?
- We haven't mapped this product's purpose to our evidence data yet — it'll be graded on the next content refresh.
Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.
Why this rating?
- The label discloses an exact amount for 0 of its 2 active ingredients.
- “Optimized Fucoxanthin-Slim Blend” is a proprietary blend — the label gives one combined amount (200 mg) without saying how much of each component you get.
- “Xanthigen” is listed as a grouped ingredient — the label doesn't break down how much of each component you get.
The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.
Why this rating?
- 1 of the 1 matched ingredient can interact with medications — Pomegranate.
- The most serious interaction on file is rated Moderate.
- Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
- For scale: 923 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.
Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.
Why this rating?
- We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
- Pregnancy & breastfeeding safety ratings cover 1 of 1.
- General safety write-ups exist for 1 of 1.
- Remember: this measures how much safety information exists. Thin data is not the same as being safe.
HelloPharmacist summaryFormula with limited ingredient disclosure with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
Assessment coverage: 1 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Sep 22, 2016.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Fucoxanthin-Slim, straight from the product label.
| Brand | Life Extension |
|---|---|
| Barcode (UPC) | 737870993094 |
| Net contents | 90 Softgel(s) |
| Market status | On market |
| Date entered into DSLD | Sep 22, 2016 |
| DSLD ID | 64368 |
| Product type | Other Combinations |
| Supplement form | Softgel Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Fucoxanthin-Slim by Life Extension, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Optimized Fucoxanthin-Slim Blend | 200 mg | -- |
| Xanthigen | 0 NP | -- |
| Wakame fucoxanthin extract | 0 NP | -- |
| Pomegranate Oil Punicic Acid extract | 0 NP | -- |
Other ingredients: Gelatin, Olive Oil, Glycerin, Beeswax, purified Water, Palm Oil, Lecithin, Caramel color
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements
Scan for product info
Results may vary.
Promotes Fat Burning and Weight Loss
To report a serious adverse event or obtain product information, contact 1-866-280-2852.
Suggested/Recommended/Usage/Directions
This supplement should be taken in conjunction with a healthy diet and regular exercise program.
Read the entire label and follow the directions carefully prior to use. DIRECTIONS: Take one (1) softgel three times daily, 15-30 minutes before meals, or as recommended by a healthcare practitioner.
Precautions
WARNINGS: KEEP OUT OF REACH OF CHILDREN.
~ Do not exceed recommended dose. ~ Do not purchase if outer seal is broken or damaged.
~ When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.
Contains soybeans.
Brand IP Statement(s)
Clinical research using Xanthigen indicates that it may take 6 weeks of consecutive use to experience significant thermogenic response.
Xanthigen is a registered trademark of Polifenoles Naturales. U.S. Patent No. 8,367,072.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Storage
Store tightly closed in a cool, dry place.
General
Q00993F
Formula
Optimized Fucoxanthin Extract Non-Stimulant Thermogenic
Contains soybeans.
FDA Statement of Identity
Dietary Supplement
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Fucoxanthin-Slim by Life Extension label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Fucoxanthin-Slim by Life Extension
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 Softgel(s) Dosage formSoftgel Capsule Amounts shown are per serving.
Optimized Fucoxanthin-Slim Blend
- › Xanthigen
Other (inactive) ingredients: Gelatin, Olive Oil, Glycerin, Beeswax, Purified Water, Palm Oil, Lecithin, Caramel color. These complete the product’s ingredient list but are not active constituents.
Fucoxanthin-Slim by Life Extension Drug Interactions
Fucoxanthin-Slim contains a single active ingredient, and it has known interactions with 922 medications. Here’s the picture, then you can look up your own drug.
Want to check YOUR meds against Fucoxanthin-Slim?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Fucoxanthin-Slim interact with 922 drugs. Click any drug to see the details.
0 of the 1 ingredient in Fucoxanthin-Slim interact with drugs. Each result below shows which ingredient is responsible.
Hydrochlorothiazide, PindololViskazide
How Hydrochlorothiazide, Pindolol interacts with Fucoxanthin-Slim — through 1 ingredient. Tap an ingredient for the detail:
Pomegranate Oil Punicic Acid ExtractAntihypertensive Drugs, Cytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, taking pomegranate with antihypertensive drugs might increase the risk of hypotension.
Read the full Pomegranate Oil Punicic Acid Extract + Hydrochlorothiazide, Pindolol interactionHydrochlorothiazide, PropranololInderide
How Hydrochlorothiazide, Propranolol interacts with Fucoxanthin-Slim — through 1 ingredient. Tap an ingredient for the detail:
Pomegranate Oil Punicic Acid ExtractCytochrome P450 2d6 (cyp2d6) Substrates, Antihypertensive Drugs Moderate
Interaction Summary
Theoretically, pomegranate might increase levels of drugs metabolized by CYP2D6.
Read the full Pomegranate Oil Punicic Acid Extract + Hydrochlorothiazide, Propranolol interactionHydrochlorothiazide, QuinaprilAccuretic
How Hydrochlorothiazide, Quinapril interacts with Fucoxanthin-Slim — through 1 ingredient. Tap an ingredient for the detail:
Pomegranate Oil Punicic Acid ExtractAntihypertensive Drugs, Ace Inhibitors (aceis) Moderate
Interaction Summary
Theoretically, taking pomegranate with antihypertensive drugs might increase the risk of hypotension.
Read the full Pomegranate Oil Punicic Acid Extract + Hydrochlorothiazide, Quinapril interactionHydrochlorothiazide, ReserpineHydropres, Serpasil-Esidrix, Serpasil-Esidrix #1, Serpasil-Esidrix #2
How Hydrochlorothiazide, Reserpine interacts with Fucoxanthin-Slim — through 1 ingredient. Tap an ingredient for the detail:
Pomegranate Oil Punicic Acid ExtractAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking pomegranate with antihypertensive drugs might increase the risk of hypotension.
Read the full Pomegranate Oil Punicic Acid Extract + Hydrochlorothiazide, Reserpine interactionHydrochlorothiazide, SpironolactoneAldactazide, Aldactide 25, Aldactide 50, Spirozine
How Hydrochlorothiazide, Spironolactone interacts with Fucoxanthin-Slim — through 1 ingredient. Tap an ingredient for the detail:
Pomegranate Oil Punicic Acid ExtractAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking pomegranate with antihypertensive drugs might increase the risk of hypotension.
Read the full Pomegranate Oil Punicic Acid Extract + Hydrochlorothiazide, Spironolactone interactionHydrochlorothiazide, TimololTimolide
How Hydrochlorothiazide, Timolol interacts with Fucoxanthin-Slim — through 1 ingredient. Tap an ingredient for the detail:
Pomegranate Oil Punicic Acid ExtractAntihypertensive Drugs, Cytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, taking pomegranate with antihypertensive drugs might increase the risk of hypotension.
Read the full Pomegranate Oil Punicic Acid Extract + Hydrochlorothiazide, Timolol interactionHydrochlorothiazide, TriamtereneDyazide, Maxzide, Maxzide-25, Triamzide, Triazide
How Hydrochlorothiazide, Triamterene interacts with Fucoxanthin-Slim — through 1 ingredient. Tap an ingredient for the detail:
Pomegranate Oil Punicic Acid ExtractAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking pomegranate with antihypertensive drugs might increase the risk of hypotension.
Read the full Pomegranate Oil Punicic Acid Extract + Hydrochlorothiazide, Triamterene interactionHydrochlorothiazide, ValsartanDiovan HCT
How Hydrochlorothiazide, Valsartan interacts with Fucoxanthin-Slim — through 1 ingredient. Tap an ingredient for the detail:
Pomegranate Oil Punicic Acid ExtractAntihypertensive Drugs, Cytochrome P450 2c9 (cyp2c9) Substrates Moderate
Interaction Summary
Theoretically, taking pomegranate with antihypertensive drugs might increase the risk of hypotension.
Read the full Pomegranate Oil Punicic Acid Extract + Hydrochlorothiazide, Valsartan interactionHydrocodoneHydrocodone, Zohydro ER
How Hydrocodone interacts with Fucoxanthin-Slim — through 1 ingredient. Tap an ingredient for the detail:
Pomegranate Oil Punicic Acid ExtractCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, pomegranate might increase levels of drugs metabolized by CYP2D6.
Read the full Pomegranate Oil Punicic Acid Extract + Hydrocodone interactionHydrocodone BitartrateHysingla, Vantrela ER
How Hydrocodone Bitartrate interacts with Fucoxanthin-Slim — through 1 ingredient. Tap an ingredient for the detail:
Pomegranate Oil Punicic Acid ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, pomegranate might increase levels of drugs metabolized by CYP3A4, but most research suggests this interaction is unlikely to be clinically significant.
Read the full Pomegranate Oil Punicic Acid Extract + Hydrocodone Bitartrate interactionHydrocodone, IbuprofenVicoprofen
How Hydrocodone, Ibuprofen interacts with Fucoxanthin-Slim — through 1 ingredient. Tap an ingredient for the detail:
Pomegranate Oil Punicic Acid ExtractCytochrome P450 2c9 (cyp2c9) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates +1 Moderate
Interaction Summary
Theoretically, pomegranate might increase levels of drugs metabolized by CYP2C9.
Read the full Pomegranate Oil Punicic Acid Extract + Hydrocodone, Ibuprofen interactionHydrocodone, PseudoephedrineP-V-Tussin, Rezira
How Hydrocodone, Pseudoephedrine interacts with Fucoxanthin-Slim — through 1 ingredient. Tap an ingredient for the detail:
Pomegranate Oil Punicic Acid ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, pomegranate might increase levels of drugs metabolized by CYP3A4, but most research suggests this interaction is unlikely to be clinically significant.
Read the full Pomegranate Oil Punicic Acid Extract + Hydrocodone, Pseudoephedrine interactionHydrocodone, Pseudoephedrine, ChlorpheniramineZutripro
How Hydrocodone, Pseudoephedrine, Chlorpheniramine interacts with Fucoxanthin-Slim — through 1 ingredient. Tap an ingredient for the detail:
Pomegranate Oil Punicic Acid ExtractCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, pomegranate might increase levels of drugs metabolized by CYP2D6.
Read the full Pomegranate Oil Punicic Acid Extract + Hydrocodone, Pseudoephedrine, Chlorpheniramine interactionHydrocodone/chlorpheniramineTussionex
How Hydrocodone/chlorpheniramine interacts with Fucoxanthin-Slim — through 1 ingredient. Tap an ingredient for the detail:
Pomegranate Oil Punicic Acid ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, pomegranate might increase levels of drugs metabolized by CYP3A4, but most research suggests this interaction is unlikely to be clinically significant.
Read the full Pomegranate Oil Punicic Acid Extract + Hydrocodone/chlorpheniramine interactionHydroflumethiazideSaluron
How Hydroflumethiazide interacts with Fucoxanthin-Slim — through 1 ingredient. Tap an ingredient for the detail:
Pomegranate Oil Punicic Acid ExtractAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking pomegranate with antihypertensive drugs might increase the risk of hypotension.
Read the full Pomegranate Oil Punicic Acid Extract + Hydroflumethiazide interactionHydroflumethiazide, ReserpineSalutensin, Salutensin-Demi
How Hydroflumethiazide, Reserpine interacts with Fucoxanthin-Slim — through 1 ingredient. Tap an ingredient for the detail:
Pomegranate Oil Punicic Acid ExtractAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking pomegranate with antihypertensive drugs might increase the risk of hypotension.
Read the full Pomegranate Oil Punicic Acid Extract + Hydroflumethiazide, Reserpine interactionIbuprofen, HydrocodoneIbucodone
How Ibuprofen, Hydrocodone interacts with Fucoxanthin-Slim — through 1 ingredient. Tap an ingredient for the detail:
Pomegranate Oil Punicic Acid ExtractCytochrome P450 2d6 (cyp2d6) Substrates, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, pomegranate might increase levels of drugs metabolized by CYP2D6.
Read the full Pomegranate Oil Punicic Acid Extract + Ibuprofen, Hydrocodone interactionIbuprofen, OxycodoneCombunox
How Ibuprofen, Oxycodone interacts with Fucoxanthin-Slim — through 1 ingredient. Tap an ingredient for the detail:
Pomegranate Oil Punicic Acid ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, pomegranate might increase levels of drugs metabolized by CYP3A4, but most research suggests this interaction is unlikely to be clinically significant.
Read the full Pomegranate Oil Punicic Acid Extract + Ibuprofen, Oxycodone interactionIloprostAurlumyn, Ventavis
How Iloprost interacts with Fucoxanthin-Slim — through 1 ingredient. Tap an ingredient for the detail:
Pomegranate Oil Punicic Acid ExtractAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking pomegranate with antihypertensive drugs might increase the risk of hypotension.
Read the full Pomegranate Oil Punicic Acid Extract + Iloprost interactionImipramineTofranil, Tofranil PM
How Imipramine interacts with Fucoxanthin-Slim — through 1 ingredient. Tap an ingredient for the detail:
Pomegranate Oil Punicic Acid ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates +1 Moderate
Interaction Summary
Theoretically, pomegranate might increase levels of drugs metabolized by CYP3A4, but most research suggests this interaction is unlikely to be clinically significant.
Read the full Pomegranate Oil Punicic Acid Extract + Imipramine interactionIndapamideLozide, Lozol
How Indapamide interacts with Fucoxanthin-Slim — through 1 ingredient. Tap an ingredient for the detail:
Pomegranate Oil Punicic Acid ExtractAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking pomegranate with antihypertensive drugs might increase the risk of hypotension.
Read the full Pomegranate Oil Punicic Acid Extract + Indapamide interactionIrbesartanAprovel, Avapro
How Irbesartan interacts with Fucoxanthin-Slim — through 1 ingredient. Tap an ingredient for the detail:
Pomegranate Oil Punicic Acid ExtractAntihypertensive Drugs, Cytochrome P450 2c9 (cyp2c9) Substrates Moderate
Interaction Summary
Theoretically, taking pomegranate with antihypertensive drugs might increase the risk of hypotension.
Read the full Pomegranate Oil Punicic Acid Extract + Irbesartan interactionIrbesartan, HydrochlorothiazideCoAprovel
How Irbesartan, Hydrochlorothiazide interacts with Fucoxanthin-Slim — through 1 ingredient. Tap an ingredient for the detail:
Pomegranate Oil Punicic Acid ExtractCytochrome P450 2c9 (cyp2c9) Substrates, Antihypertensive Drugs Moderate
Interaction Summary
Theoretically, pomegranate might increase levels of drugs metabolized by CYP2C9.
Read the full Pomegranate Oil Punicic Acid Extract + Irbesartan, Hydrochlorothiazide interactionIsosorbide Dinitrate, HydralazineBiDil
How Isosorbide Dinitrate, Hydralazine interacts with Fucoxanthin-Slim — through 1 ingredient. Tap an ingredient for the detail:
Pomegranate Oil Punicic Acid ExtractAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking pomegranate with antihypertensive drugs might increase the risk of hypotension.
Read the full Pomegranate Oil Punicic Acid Extract + Isosorbide Dinitrate, Hydralazine interactionIsradipineDynacirc CR
How Isradipine interacts with Fucoxanthin-Slim — through 1 ingredient. Tap an ingredient for the detail:
Pomegranate Oil Punicic Acid ExtractAntihypertensive Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, taking pomegranate with antihypertensive drugs might increase the risk of hypotension.
Read the full Pomegranate Oil Punicic Acid Extract + Isradipine interactionLabetalolNormodyne, Trandate
How Labetalol interacts with Fucoxanthin-Slim — through 1 ingredient. Tap an ingredient for the detail:
Pomegranate Oil Punicic Acid ExtractAntihypertensive Drugs Moderate
Interaction Summary
Theoretically, taking pomegranate with antihypertensive drugs might increase the risk of hypotension.
Read the full Pomegranate Oil Punicic Acid Extract + Labetalol interactionLercanidipine HydrochlorideZanidip
How Lercanidipine Hydrochloride interacts with Fucoxanthin-Slim — through 1 ingredient. Tap an ingredient for the detail:
Pomegranate Oil Punicic Acid ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Antihypertensive Drugs Moderate
Interaction Summary
Theoretically, pomegranate might increase levels of drugs metabolized by CYP3A4, but most research suggests this interaction is unlikely to be clinically significant.
Read the full Pomegranate Oil Punicic Acid Extract + Lercanidipine Hydrochloride interactionLevamlodipineConjupri
How Levamlodipine interacts with Fucoxanthin-Slim — through 1 ingredient. Tap an ingredient for the detail:
Pomegranate Oil Punicic Acid ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Antihypertensive Drugs Moderate
Interaction Summary
Theoretically, pomegranate might increase levels of drugs metabolized by CYP3A4, but most research suggests this interaction is unlikely to be clinically significant.
Read the full Pomegranate Oil Punicic Acid Extract + Levamlodipine interactionLidocaineDilocaine, Duo-Trach Kit, Lidoderm, Lidoject-1, Lidoject-2, Nervocaine +4 more
How Lidocaine interacts with Fucoxanthin-Slim — through 1 ingredient. Tap an ingredient for the detail:
Pomegranate Oil Punicic Acid ExtractCytochrome P450 3a4 (cyp3a4) Substrates, Cytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, pomegranate might increase levels of drugs metabolized by CYP3A4, but most research suggests this interaction is unlikely to be clinically significant.
Read the full Pomegranate Oil Punicic Acid Extract + Lidocaine interactionLisdexamfetamineVyvanse
How Lisdexamfetamine interacts with Fucoxanthin-Slim — through 1 ingredient. Tap an ingredient for the detail:
Pomegranate Oil Punicic Acid ExtractCytochrome P450 2d6 (cyp2d6) Substrates Moderate
Interaction Summary
Theoretically, pomegranate might increase levels of drugs metabolized by CYP2D6.
Read the full Pomegranate Oil Punicic Acid Extract + Lisdexamfetamine interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Fucoxanthin-Slim with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Brand information
Manufacturer and brand details for Fucoxanthin-Slim, from the product label.
Life Extension
See all Life Extension products- Name
- Quality Supplements and Vitamins, Inc.
- City
- Ft. Lauderdale
- State
- Florida
- ZipCode
- 33309
- Phone Number
- 1-866-280-2852
- Web Address
- www.lef.org
Fucoxanthin-Slim by Life Extension: Common Questions
Does Fucoxanthin-Slim by Life Extension interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Fucoxanthin-Slim is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
Sources & How We Checked
Fucoxanthin-Slim's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 27 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Pomegranate 27 references
- Igea JM, Cuesta J, Cuevas M, et al. Adverse reaction to pomegranate ingestion. Allergy 1991;46:472-4. DOI
- Gaig P, Bartolome B, Lleonart R, et al. Allergy to pomegranate (Punica granatum). Allergy 1999;54:287-8.
- Aviram M, Dornfeld L. Pomegranate juice consumption inhibits serum angiotensin converting enzyme activity and reduces systolic blood pressure. Atherosclerosis 2001;158:195-8. PubMed
- Valsecchi R, Reseghetti A, Leghissa P, et al. Immediate contact hypersensitivity to pomegranate. Contact Dermatitis 1998;38:44-5. PubMed
- Esmaillzadeh A, Tahbaz F, Gaieni I, et al. Concentrated pomegranate juice improves lipid profiles in diabetic patients with hyperlipidemia. J Med Food 2004;7:305-8. PubMed
- Aviram M, Rosenblat M, Gaitini D, et al. Pomegranate juice consumption for 3 years by patients with carotid artery stenosis reduces common carotid intima-media thickness, blood pressure and LDL oxidation. Clin Nutr 2004;23:423-33. DOI
- Hidaka M, Okumura M, Fujita K, et al. Effects of pomegranate juice on human cytochrome p450 3A (CYP3A) and carbamazepine pharmacokinetics in rats. Drug Metab Dispos 2005;33:644-8. PubMed
- Loren DJ, Seeram NP, Schulman RN, Holtzman DM. Maternal dietary supplementation with pomegranate juice is neuroprotective in an animal model of neonatal hypoxic-ischemic brain injury. Pediatr Res 2005;57:858-64. PubMed
- Kim ND, Mehta R, Yu W, et al. Chemopreventive and adjuvant therapeutic potential of pomegranate (Punica granatum) for human breast cancer. Breast Cancer Res Treat 2002;71:203-17. PubMed
- Sorokin AV, Duncan B, Panetta R, Thompson PD. Rhabdomyolysis associated with pomegranate juice consumption. Am J Cardiol 2006;98:705-6. PubMed
- Farkas D, Oleson LE, Zhao Y, et al. Pomegranate juice does not impair clearance of oral or intravenous midazolam, a probe for cytochrome P450-3A activity: comparison with grapefruit juice. J Clin Pharmacol 2007;47:286-94. PubMed
- Yeo C, Shon J, Liu K, et al. The effects of pomegranate juice on the pharmacokinetics of simvastatin in healthy Korean subjects (PI-63). Clin Pharmacol Ther 2006;79:23.
- Farkas D, Greenblatt DJ. Influence of fruit juices on drug disposition: discrepancies between in vitro and clinical studies. Expert Opin Drug Metab Toxicol 2008;4:381-93.
- Nagata M, Hidaka M, Sekiya H, et al. Effects of pomegranate juice on human cytochrome P450 2C9 and tolbutamide pharmacokinetics in rats. Drug Metab Dispos 2007;35:302-5. PubMed
- Komperda KE. Potential interaction between pomegranate juice and warfarin. Pharmacotherapy 2009;29:1002-6. PubMed
- Gangemi S, Mistrello G, Roncarolo D, et al. Pomegranate-dependent exercise-induced anaphylaxis. J Investig Allergol Clin Immunol 2008;18:491-2.
- Misaka S, Nakamura R, Uchida S, et al. Effect of 2 weeks' consumption of pomegranate juice on the pharmacokinetics of a single dose of midazolam: an open-label, randomized, single-center, 2-period crossover study in healthy Japanese volunteers. Clin Ther PubMed
- Jarvis S, Li C, Bogle RG. Possible interaction between pomegranate juice and warfarin. Emerg Med J 2010;27:74-5. PubMed
- Esmaillzadeh, A., Tahbaz, F., Gaieni, I., Alavi-Majd, H., and Azadbakht, L. Cholesterol-lowering effect of concentrated pomegranate juice consumption in type II diabetic patients with hyperlipidemia. Int J Vitam.Nutr Res 2006;76(3):147-151. PubMed
- Forest, C. P., Padma-Nathan, H., and Liker, H. R. Efficacy and safety of pomegranate juice on improvement of erectile dysfunction in male patients with mild to moderate erectile dysfunction: a randomized, placebo-controlled, double-blind, crossover study PubMed
- Wright, H. and Pipkin F. B. Pomegranates (Punica granatum), kiwifruit (Actinidia deliciosa) and blood pressure: a pilot study. Proceedings of the Nutrition Society 2008;67(8):1.
- Sohrab G, Sotoodeh G, Siasi F, et al. Effect of pomegranate juice consumption on blood pressure in type 2 diabetic patients. Iranian Journal of Endocrinology and Metabolism 2008;9:399-405, 470.
- Enrique E, Utz M, De Mateo JA, et al. Allergy to lipid transfer proteins: cross-reactivity among pomegranate, hazelnut, and peanut. Ann Allergy Asthma Immunol 2006;96(1):122-3. PubMed
- Hanley MJ, Masse G, Harmatz JS, et al. Pomegranate juice and pomegranate extract do not impair oral clearance of flurbiprofen in human volunteers: divergence from in vitro results. Clin Pharmacol Ther 2012;92(5):651-7. PubMed
- Paller CJ, Ye X, Wozniak PJ, et al. A randomized phase II study of pomegranate extract for men with rising PSA following initial therapy for localized prostate cancer. Prostate Cancer Prostatic Dis 2013;16(1):50-5. PubMed
- Park SJ, Yeo CW, Shim EJ, et al. Pomegranate juice does not affect the disposition of simvastatin in healthy subjects. Eur J Drug Metab Pharmacokinet 2016;41(4):339-44. PubMed
- Ross MM, Cherkerzian S, Mikulis ND, et al. A randomized controlled trial investigating the impact of maternal dietary supplementation with pomegranate juice on brain injury in infants with IUGR. Sci Rep. 2021;11(1):3569. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC