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Dietary supplement

Glycine + Taurine & L-Proline Unflavored Ingredients & Drug Interactions

by Pure Power

Glycine + Taurine & L-Proline Unflavored label
See full label image
Powder Category: Amino Acid/protein
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Glycine + Taurine & L-Proline Unflavored against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Glycine + Taurine & L-Proline Unflavored is a dietary supplement by Pure Power with 3 active ingredients. Its ingredients are commonly taken for sleep quality and insomnia, relaxation, cognitive function.Based on those ingredients, 174 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Taurine, Glycine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Glycine + Taurine & L-Proline Unflavored by Pure Power

Ask about any prescription or over-the-counter medication and we check it for interactions with Glycine + Taurine & L-Proline Unflavored by Pure Power — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Glycine + Taurine & L-Proline Unflavored by Pure Power

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 3 of its 3 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This powder contains three active ingredients. Glycine is an amino acid that's been studied for schizophrenia and a few other conditions.

Taurine is another amino acid naturally found in meat and seafood; it's been researched for heart health and liver function. L-Proline is an amino acid involved in collagen and connective tissue.

The product has no inactive ingredients listed.

Does it work?

Insufficient evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Insufficient

There isn't enough reliable clinical evidence to rate this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: Support collagen, recovery and muscle performance.
  • We looked for evidence on: Athletic performance, Exercise-induced muscle soreness, Physical performance, Postoperative recovery, Wound healing, Fractures — and 4 related terms.
  • The closest evidence on file: Taurine is rated "Insufficient Reliable Evidence To Rate" for Athletic performance (Natural Medicines).
  • Also on file: Taurine is rated "Insufficient Reliable Evidence To Rate" for Exercise-induced muscle soreness, Fatigue, Physical performance, Postoperative recovery.
  • Also on file: Glycine is rated "Insufficient Reliable Evidence To Rate" for Wound healing, Physical performance.

Glycine is possibly effective for schizophrenia. For the other conditions listed—ADHD, benign prostatic hyperplasia, and a few others—the evidence isn't established enough to rate it.

Taurine is possibly effective for hepatitis and congestive heart failure (a weakened heart that can't pump blood well). It appears possibly ineffective for weight loss.

L-Proline's effectiveness for athletic performance, bone health, fracture healing, and wound healing isn't established in the data we hold.

The evidence, ingredient by ingredient Glycine Proline Taurine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Glycine is generally well tolerated at typical doses, but long-term safety data are limited. Rare side effects include mild sedation, and some people report soft stools, nausea, vomiting, or stomach discomfort—symptoms that resolve quickly if you stop.

Other reported effects like irritability, insomnia, fatigue, headache, and dry mouth may or may not be linked to glycine. Taurine is generally well tolerated short-term in healthy adults, though long-term safety is less clear.

The most common side effects are constipation, diarrhea, and indigestion. Rarely, hypersensitivity reactions have occurred, especially in people with a history of allergies to sulfonamides or sulfites.

Case reports in energy drinks raise concern for serious heart effects, but it's unclear whether taurine alone or other ingredients are responsible. L-Proline safety from supplements hasn't been well studied.

There's no pregnancy and lactation data on file for glycine or L-Proline; taurine is likely safe in pregnancy and lactation (it's naturally in breast milk), but supplement doses haven't been studied well, so use caution.

Side effects, ingredient by ingredient Glycine Proline Taurine

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 3 matched ingredients can interact with medications — Taurine, Glycine.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: lithium.
  • For scale: 174 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take clozapine (Clozaril) for schizophrenia, blood pressure medications (antihypertensives), or lithium for bipolar disorder, check with your pharmacist before starting this product. Glycine may reduce clozapine's effectiveness; taurine may lower blood pressure further or increase lithium levels.

No interactions are documented for L-Proline with the medications we could check.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with insufficient evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This product may help with schizophrenia or heart conditions, though the evidence varies. If you take clozapine, blood pressure medications, or lithium, check with us first—these interactions matter.

Even if you don't take those, run your full medication list through our checker. Talk to your pharmacist about whether it fits your needs.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Mar 25, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Glycine + Taurine & L-Proline Unflavored, straight from the product label.

Brand Pure Power
Barcode (UPC) 810094213756
Net contents 5.2 Ounce(s); 147 Gram(s)
Market status On market
Date entered into DSLD Mar 25, 2025
DSLD ID 327166
Product type Amino Acid/protein
Supplement form Powder
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Glycine + Taurine & L-Proline Unflavored by Pure Power, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
4.9 Gram(s)
Maximum serving Sizes:
4.9 Gram(s)
Servings per container
30
UPC/BARCODE
810094213756
IngredientAmount% DV
Glycine4 Gram(s)--
L-Proline250 mg--
Taurine500 mg--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Replenish for the strongest version of you

We believe in fueling your body with the right ingredients, so you have the power to become the strongest version of you.

Formula

This NSF Certified for Sport blend replenishes your body with a trio of key amino acids to support collagen building and cellular health, while also delaying muscle fatigue and helping aid your body's recovery and revitalization post exercise.

4 g Glycine | 500 mg Taurine | 250 mg L-Proline per serving

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Precautions

Keep out of reach of children.

Do not use if safety seal is torn or damaged.

If you are nursing, pregnant, taking medication or have a medical condition, consult your physician before taking this product.

Seals/Symbols

NSF Certified Sport

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Suggested use: Adults, as a dietary supplement, mix one (1) scoop (4.9g) with 8-12 fl. oz. of water or beverage of choice, before, during or after a workout.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Glycine + Taurine & L-Proline Unflavored by Pure Power label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Glycine + Taurine & L-Proline Unflavored label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Glycine + Taurine & L-Proline Unflavored by Pure Power

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size4.9 Gram(s) Dosage formPowder Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Glycine

Interacts with
1 drug
4 Gram(s) per serving

Glycine is a non-essential amino acid your body makes on its own and that also appears in protein-rich foods. It is most studied for improving sleep q...

Glycine monograph & interactions

L-Proline

No known
interactions
250 mg per serving

Proline is a non-essential amino acid that your body can make on its own and that you also get from protein-rich foods. It is a key building block of...

L-Proline monograph & interactions

Taurine

Interacts with
173 drugs
500 mg per serving

Taurine is an amino acid your body makes naturally and that you also get from animal foods. It is widely used in energy drinks and sports supplements,...

Taurine monograph & interactions
Interaction report

Glycine + Taurine & L-Proline Unflavored by Pure Power Drug Interactions

Want to check YOUR meds against Glycine + Taurine & L-Proline Unflavored?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
174Drugs
174 Moderate

Ingredients driving the most interactions

Taurine 173
Glycine 1

Individual Drug Interactions

The ingredients in Glycine + Taurine & L-Proline Unflavored interact with 174 drugs. Click any drug to see the details.

2 of the 3 ingredients in Glycine + Taurine & L-Proline Unflavored interact with drugs. Each result below shows which ingredient is responsible. Taurine Glycine

Each ingredient & the kinds of drugs it affects

For each ingredient in Glycine + Taurine & L-Proline Unflavored with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Taurine2 drug types · 173 drugs

Antihypertensive Drugs

Theoretically, taurine might increase the risk of hypotension when taken with antihypertensive drugs.
Some clinical evidence suggests that taurine can reduce both systolic and diastolic blood pressure.

Likelihood Probable Evidence D
Lithium

Theoretically, taurine might reduce excretion and increase plasma levels of lithium.
Taurine is thought to have diuretic properties, which might reduce the excretion of lithium.

Likelihood Probable Evidence D
Taurine full monograph & interactions

Glycine1 drug type · 1 drug

Clozapine (Clozaril)

Theoretically, glycine might decrease the effectiveness of clozapine.
One small clinical study in patients with schizophrenia shows that adding glycine to clozapine therapy worsens symptoms of schizophrenia when compared with clozapine alone. The mechanism of this interaction is unclear.

Likelihood Probable Evidence B
Glycine full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Glycine + Taurine & L-Proline Unflavored, from the product label.

Pure Power

See all Pure Power products
Name
NHP
Street Address
125 SW 3rd Place
City
Cape Coral
State
FL
ZipCode
33991
Phone Number
(877) 985-2696
Pharmacist Counseling Corner

Glycine + Taurine & L-Proline Unflavored by Pure Power: Common Questions

Does Glycine + Taurine & L-Proline Unflavored by Pure Power interact with any medications?
Yes. Based on its ingredients, Glycine + Taurine & L-Proline Unflavored has a known interaction with 174 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Glycine + Taurine & L-Proline Unflavored contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is this safe during pregnancy or while breastfeeding?
Taurine is likely safe during pregnancy and lactation—it's natural in breast milk. But we don't have enough safety data on glycine or L-Proline at supplemental doses during pregnancy or breastfeeding. Talk with your doctor or pharmacist for personalized advice if you're pregnant, planning pregnancy, or nursing.
What are the most common side effects?
Most people tolerate this product well. Taurine can occasionally cause constipation, diarrhea, or indigestion. Glycine rarely causes mild sedation or stomach upset. If you're sensitive to sulfites or sulfonamides, watch for allergic reactions.
Can this help with schizophrenia?
Glycine is possibly effective for schizophrenia according to the evidence we hold. However, one small study found that adding glycine to clozapine (a common antipsychotic) actually worsened symptoms. This product isn't a replacement for prescribed treatment—talk with your doctor if you're interested in it.
How long is it safe to use?
Taurine is well tolerated for up to one year, though long-term safety is less certain. Glycine's long-term safety data are limited. Work with your doctor or pharmacist on how long to use it.
What does each ingredient do?
Glycine and taurine are amino acids your body makes naturally. Glycine has been studied for schizophrenia. Taurine has been researched for heart and liver health. L-Proline is an amino acid involved in connective tissue, but evidence for it as a supplement isn't established.
Does it have fillers?
No inactive ingredients are listed for this product.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Glycine + Taurine & L-Proline Unflavored is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Glycine + Taurine & L-Proline Unflavored label
Go deeper

The Full Monographs Behind Glycine + Taurine & L-Proline Unflavored’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Glycine

Interacts with 1 drug

Glycine is a non-essential amino acid your body makes on its own and that also appears in protein-rich foods. It is most studied for improving sleep quality, where early research is promisin...

Read the full Glycine monograph → Herb & supplement monograph

Proline

Proline is a non-essential amino acid that your body can make on its own and that you also get from protein-rich foods. It is a key building block of collagen, but strong human evidence that...

Read the full Proline monograph → Herb & supplement monograph

Taurine

Interacts with 173 drugs

Taurine is an amino acid your body makes naturally and that you also get from animal foods. It is widely used in energy drinks and sports supplements, and short-term use appears generally sa...

Read the full Taurine monograph →
Sources

Sources & How We Checked

Glycine + Taurine & L-Proline Unflavored's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 30 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Glycine 5 references
  1. Heresco-Levy U, Javitt DC, Ermilov M, et al. Efficacy of high-dose glycine in the treatment of enduring negative symptoms of schizophrenia. Arch Gen Psychiatry 1999;56:29-36.. PubMed
  2. Potkin SG, Jin Y, Bunney BG, Costa J, Gulasekaram B. Effect of clozapine and adjunctive high-dose glycine in treatment-resistant schizophrenia. Am J Psychiatry 1999;156:145-7.. PubMed
  3. Gusev EI, Skvortsova VI, Dambinova SA, et al. Neuroprotective effects of glycine for therapy of acute ischaemic stroke. Cerebrovasc Dis 2000;10:49-60. PubMed
  4. Inagawa K, Kawai N, Ono K, Sukegawa E, Tsubuku S, Takahashi M. Assessment of acute adverse effects of glycine ingestion at a high dose in human volunteers. Seikatsu Eisei. 2006; 50:27-32.
  5. Woods SW, Walsh BC, Hawkins KA, Miller TJ, Saksa JR, D'Souza DC, Pearlson GD, Javitt DC, McGlashan TH, Krystal JH. Glycine treatment of the risk syndrome for psychosis: report of two pilot studies. Eur Neuropsychopharmacol. 2013 Aug;23(8):931-40. PubMed

See these in context on the Glycine monograph →

Proline 4 references
  1. Jennings A, MacGregor A, Spector T, Cassidy A. Amino acid intakes are associated with bone mineral density and prevalence of low bone mass in women: Evidence from discordant monozygotic twins. J Bone Miner Res. 2016;31(2):326-35. PubMed
  2. Gracia-Marco L, Bel-Serrat S, Cuenca-Garcia M, et al. Amino acids intake and physical fitness among adolescents. Amino Acids. 2017;49(6):1041-1052. PubMed
  3. Jamdar J, Rao B, Netke S, et al. Reduction in tibial shaft fracture healing time with essential nutrient supplementation containing ascorbic acid, lysine, and proline. J Altern Complement Med. 2004;10(6):915-6.
  4. Mehl AA, Damião AO, Viana SD, Andretta CP. Hard-to-heal wounds: a randomised trial of an oral proline-containing supplement to aid repair. J Wound Care 2021;30(1):26-31. PubMed

See these in context on the Proline monograph →

Taurine 21 references
  1. Ahmad S, Robertson HT, Golper TA, et al. Multicenter trial of L-carnitine in maintenance hemodialysis patients. II. Clinical and biochemical effects. Kidney Int 1990;38:912-8. PubMed
  2. Machado-Vieira R, Viale CI, Kapczinski F. Mania associated with an energy drink: the possible role of caffeine, taurine, and inositol. Can J Psychiatry 2001;46:454-5. PubMed
  3. Obermann M, Schorn CF, Mummel P, et al. Taurine induced toxic encephalopathy? Clin Neurol Neurosurg 2006;108:812-3. PubMed
  4. Bichler, A., Swenson, A., and Harris, M. A. A combination of caffeine and taurine has no effect on short term memory but induces changes in heart rate and mean arterial blood pressure. Amino Acids 2006;31(4):471-476. PubMed
  5. Iyadurai, S. J. and Chung, S. S. New-onset seizures in adults: possible association with consumption of popular energy drinks. Epilepsy Behav 2007;10(3):504-508. PubMed
  6. Berger, A. J. and Alford, K. Cardiac arrest in a young man following excess consumption of caffeinated "energy drinks". Med J Aust. 1-5-2009;190(1):41-43. PubMed
  7. Worthley, M. I., Prabhu, A., De, Sciscio P., Schultz, C., Sanders, P., and Willoughby, S. R. Detrimental effects of energy drink consumption on platelet and endothelial function. Am J Med 2010;123(2):184-187. PubMed
  8. Morchon, Simon D. and Perez Castrillon, J. L. [Hypoglycemia by intake of taurine]. Rev.Clin Esp. 2010;210(1):49.
  9. Livshits, Z., Hoffman, R. S., Hymes, K. B., and Nelson, L. S. If vitamins could kill: massive hemolysis following naturopathic vitamin infusion. J Med Toxicol. 2011;7(3):224-226. PubMed
  10. Schoffl, I., Kothmann, J. F., Schoffl, V., Rupprecht, H. D., and Rupprecht, T. "Vodka energy": too much for the adolescent nephron? Pediatrics 2011;128(1):e227-e231. PubMed
  11. Calabro, R. S., Italiano, D., Gervasi, G., and Bramanti, P. Single tonic-clonic seizure after energy drink abuse. Epilepsy Behav 2012;23(3):384-385. PubMed
  12. Fujita, T., Ando, K., Noda, H., Ito, Y., and Sato, Y. Effects of increased adrenomedullary activity and taurine in young patients with borderline hypertension. Circulation 1987;75(3):525-532. PubMed
  13. Darling, P. B., Lepage, G., Leroy, C., Masson, P., and Roy, C. C. Effect of taurine supplements on fat absorption in cystic fibrosis. Pediatr Res 1985;19(6):578-582. PubMed
  14. Fukuyama, Y. and Ochiai, Y. Therapeutic trial by taurine for intractable childhood epilepsies. Brain Dev. 1982;4(1):63-69. PubMed
  15. Franconi, F., Bennardini, F., Mattana, A., Miceli, M., Ciuti, M., Mian, M., Gironi, A., Anichini, R., and Seghieri, G. Plasma and platelet taurine are reduced in subjects with insulin-dependent diabetes mellitus: effects of taurine supplementation. Am.J. DOI
  16. Stohs SJ, Miller M. A case study involving allergic reactions to sulfur-containing compounds including, sulfite, taurine, acesulfame potassium and sulfonamides. Food Chem Toxicol. 2014 Jan;63:240-3. PubMed
  17. Sun Q, Wang B, Li Y, Sun F, et al. Taurine supplementation lowers blood pressure and improves vascular function in prehypertension: randomized, double-blind, placebo-controlled study. Hypertension 2016 Mar;67(3):541-9. PubMed
  18. Jang ES, Hwang SH, Kim JW, Jeong SH. Effectiveness of 4-week oral taurine treatment for muscle cramps in patients with liver cirrhosis: a single-arm pilot study. Yonsei Med J 2021;62(1):21-8. PubMed
  19. Guan L, Miao P. The effects of taurine supplementation on obesity, blood pressure and lipid profile: A meta-analysis of randomized controlled trials. Eur J Pharmacol 2020;885:173533. PubMed
  20. Higgins JP, Liras GN, Liras IN, et al. Energy Drink Effects on Hemodynamics and Endothelial Function in Young Adults. Cardiology. 2021;146(2):258-262. PubMed
  21. Pallangyo P, Bhalia SV, Komba M, et al. Acute Myocardial Infarction Following the Consumption of Energy Drink in a 28-Year-Old Male: A Case Report. J Investig Med High Impact Case Rep. 2023 Jan-Dec;11:23247096231168811. PubMed

See these in context on the Taurine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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