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Dietary supplement

Gotu Kola 300 mg Ingredients & Drug Interactions

by Eclectic Herb

Gotu Kola 300 mg label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Gotu Kola 300 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Gotu Kola 300 mg is a dietary supplement by Eclectic Herb with 1 active ingredient. Its ingredients are commonly taken for wound healing, varicose veins and poor circulation, anxiety and stress.Based on those ingredients, 579 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Gotu Kola. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Gotu Kola 300 mg by Eclectic Herb

Ask about any prescription or over-the-counter medication and we check it for interactions with Gotu Kola 300 mg by Eclectic Herb — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Gotu Kola 300 mg by Eclectic Herb

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: gotu kola at 300 mg per capsule. Gotu kola is a plant traditionally used in Asian medicine, and modern research has looked at its effects on circulation and skin.

The capsule also contains hypromellose, an inactive ingredient used to form the capsule shell itself.

Does it work?

Leans against
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Leans against

The strongest graded evidence we hold for the stated purpose leans against a benefit.

Why this rating?
  • The label markets this product for: Supports cognitive function.
  • We looked for evidence on: Cognitive function, Alzheimer disease, Attention deficit-hyperactivity disorder (ADHD), Depression, Generalized anxiety disorder (GAD), Memory — and 2 related terms.
  • The closest evidence on file: Gotu Kola is rated "Possibly Ineffective" for Cognitive function (Natural Medicines).
  • Also on file: Gotu Kola is rated "Insufficient Reliable Evidence To Rate" for Alzheimer disease, Generalized anxiety disorder (GAD), Attention deficit-hyperactivity disorder (ADHD), Depression.

The evidence for gotu kola is mixed. It's rated possibly effective for venous insufficiency (poor circulation in the legs) and burns.

For radiation dermatitis, cognitive function, and Alzheimer disease, the evidence is either possibly ineffective or there isn't enough reliable data to say. If you're considering it for a specific condition, talk to your pharmacist or doctor about what the research actually shows for your situation.

The evidence, ingredient by ingredient Gotu Kola

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Gotu kola is generally well tolerated in the short term, but the quality of safety evidence is limited. The most common side effects taken by mouth are stomach irritation and nausea.

Liver toxicity is rare but has been reported in case studies — though whether gotu kola was truly responsible in those cases remains unclear. The safety data advises against use during pregnancy and breastfeeding because there isn't enough information to know it's safe.

Side effects, ingredient by ingredient Gotu Kola

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Gotu Kola.
  • The most serious interaction on file is rated Moderate.
  • For scale: 580 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you start, check with your pharmacist if you take CNS depressants (sedatives, sleep aids, anxiety medications) or hepatotoxic drugs (medications that can affect liver function) — both are rated Moderate severity. Altogether, these interactions span 563 individual medications.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with graded evidence leaning against its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Gotu Kola 300 mg may be worth considering if you're looking into support for circulation or minor burns and you don't take CNS depressants or hepatotoxic medications. If you're pregnant, breastfeeding, or take any prescription drugs, talk to your pharmacist first — especially if you're on sedatives or liver-metabolized medications.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Oct 24, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Gotu Kola 300 mg, straight from the product label.

Brand Eclectic Herb
Barcode (UPC) 023363309078
Net contents 90 Veg Cap(s)
Market status On market
Date entered into DSLD Oct 24, 2024
DSLD ID 316799
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Kosher, Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Gotu Kola 300 mg by Eclectic Herb, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Veg Cap(s)
Maximum serving Sizes:
3 Veg Cap(s)
Servings per container
90
UPC/BARCODE
023363309078
IngredientAmount% DV
Gotu Kola300 mg--

Other ingredients: Hypromellose

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Concentrated 2 1/2 X through freeze-drying Freeze dried fresh for peak plant power Grown in the United States Naturally concentrated

No fillers Non GMO Gluten free

Vegan

Freeze-drying keeps the plants nutrients in the same balance as found in nature by gently removing only the water.

Supports cognitive function Small batch whole herbs

Formula

100% Kosher

Whole herb Raw food

FDA Disclaimer Statement

These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.

Precautions

Warning: Cancer and reproductive harm. www.P65Warnings.ca.gov

Keep away from children. Consult your doctor about herbs with pregnancy, infants or prescription drugs.

Consult your doctor about herbs with pregnancy, infants or prescription drugs.

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Suggested use: Take 1-3 capsules per day.

General Statements

From farm to bottle, we use naturopathic wisdom and innovative processes to create exceptional products.

@eclecticherb

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Gotu Kola 300 mg by Eclectic Herb label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Gotu Kola 300 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Gotu Kola 300 mg by Eclectic Herb

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Veg Cap(s) Dosage formCapsule Servings per container90 Amounts shown are per serving.

Gotu Kola

Interacts with
579 drugs
300 mg per serving

Gotu kola is a traditional Ayurvedic and Asian herb that people use for wound healing, circulation, skin problems, and as a calming or memory-supporti...

Gotu Kola monograph & interactions

Other (inactive) ingredients: Hypromellose. These complete the product’s ingredient list but are not active constituents.

Interaction report

Gotu Kola 300 mg by Eclectic Herb Drug Interactions

Want to check YOUR meds against Gotu Kola 300 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
579Drugs
579 Moderate

Ingredients driving the most interactions

Gotu Kola 579

Individual Drug Interactions

The ingredients in Gotu Kola 300 mg interact with 579 drugs. Click any drug to see the details.

1 of the 1 ingredient in Gotu Kola 300 mg interact with drugs. Each result below shows which ingredient is responsible. Gotu Kola

Each ingredient & the kinds of drugs it affects

For each ingredient in Gotu Kola 300 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Gotu Kola2 drug types · 579 drugs

Cns Depressants

Theoretically, taking gotu kola might increase the sedative effects of CNS depressants.
In vitro research suggests that gotu kola may have sedative effects via binding of GABA receptors.

Likelihood Possible Evidence D
Hepatotoxic Drugs

Theoretically, taking gotu kola with hepatotoxic drugs might have additive adverse effects.
There are at least four case reports of hepatotoxicity associated with the use of gotu kola. However, more information is needed to determine if gotu kola was the causative factor in these cases.

Likelihood Possible Evidence D
Gotu Kola full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Gotu Kola 300 mg, from the product label.

Eclectic Herb

See all Eclectic Herb products
Name
Eclectic Herb
Street Address
755 NE 6th St.
City
Gresham
State
Oregon
ZipCode
97030
Phone Number
503.668.4120
Web Address
www.eclecticherb.com
Pharmacist Counseling Corner

Gotu Kola 300 mg by Eclectic Herb: Common Questions

Does Gotu Kola 300 mg by Eclectic Herb interact with any medications?
Yes. Based on its ingredients, Gotu Kola 300 mg has a known interaction with 579 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Gotu Kola 300 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is gotu kola safe to use while I'm pregnant or breastfeeding?
The safety data advises against use during pregnancy because there isn't enough information. Similarly, safety during breastfeeding is unknown, so it's best avoided. Talk to your doctor or pharmacist for personalized advice.
What are the side effects I might notice?
Most people taking gotu kola by mouth experience stomach irritation or nausea if they notice anything at all. Liver toxicity is rare. Topically, it can rarely cause allergic contact dermatitis (redness, itching, and burning).
Does gotu kola actually work for brain health or memory?
The evidence isn't there yet. For cognitive function and Alzheimer disease, there either isn't enough reliable data to say or the research suggests it's possibly ineffective. If that's why you're interested, the science doesn't support it.
What is gotu kola used for?
Research suggests it's possibly effective for venous insufficiency (poor leg circulation) and burns. For other uses, the evidence is weaker or not established.
Is there concern about liver damage from gotu kola?
There are four case reports of liver toxicity linked to gotu kola, but researchers couldn't confirm gotu kola caused the damage in those cases. One clinical trial monitoring liver function found no problems at 120 mg daily for 6 months. Still, it's worth knowing the concern exists.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Gotu Kola 300 mg is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Gotu Kola 300 mg label
Go deeper

The Full Monographs Behind Gotu Kola 300 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Gotu Kola

Interacts with 579 drugs

Gotu kola is a traditional Ayurvedic and Asian herb that people use for wound healing, circulation, skin problems, and as a calming or memory-supporting herb. Some early studies suggest poss...

Read the full Gotu Kola monograph →
Sources

Sources & How We Checked

Gotu Kola 300 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 18 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Gotu Kola 18 references
  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  2. Pointel JP, Boccalon H, Cloarec M, et al. Titrated extract of Centella asiatica (TECA) in the treatment of venous insufficiency of the lower limbs. Angiol 1987;38:46-50. PubMed
  3. Brinkhaus B, Lindner M, Schuppan D, Hahn EG. Chemical, pharmacological and clinical profile of the east Asian medical plant Centella asiatica. Phytomedicine 2000;7:427-48.
  4. Eun HC, Lee AY. Contact dermatitis due to madecassol. Contact Dermatitis 1985;13:310-3.. PubMed
  5. Hausen BM. Centella asiatica (Indian pennywort), an effective therapeutic but a weak sensitizer. Contact Dermatitis 1993;29:175-9..
  6. Bilbao I, Aguirre A, Zabala R, et al. Allergic contact dermatitis from butoxyethyl nicotinic acid and Centella asiatica extract. Contact Dermatitis 1995;33:435-6.
  7. Cesarone MR, Incandela L, De Sanctis MT, et al. Evaluation of treatment of diabetic microangiopathy with total triterpenic fraction of Centella asiatica: a clinical prospective randomized trial with a microcirculatory model. Angiology 2001;52 Suppl 2 DOI
  8. Bradwejn J, Zhou Y, Koszycki D, Shlik J. A double-blind, placebo-controlled study on the effects of Gotu Kola (Centella asiatica) on acoustic startle response in healthy subjects. J Clin Psychopharmacol 2000;20:680-4. PubMed
  9. Young GL, Jewell D. Creams for preventing stretch marks in pregnancy. Cochrane Database Syst Rev 2000;(2):CD000066. PubMed
  10. Jorge OA, Jorge AD. Hepatotoxicity associated with the ingestion of Centella asiatica. Rev Esp Enferm Dig 2005;97:115-24. PubMed
  11. Mallol J, Belda MA, Costa D, et al. Prophylaxis of striae gravidarum with a topical formulation. A double blind trial. Int J Cosmet Sci 1991;3:51-7.
  12. Izu, R., Aguirre, A., Gil, N., and Diaz-Perez, J. L. Allergic contact dermatitis from a cream containing Centella asiatica extract. Contact Dermatitis 1992;26(3):192-193.
  13. Santucci, B., Picardo, M., and Cristaudo, A. Contact dermatitis due to Centelase. Contact Dermatitis 1985;13(1):39. PubMed
  14. Vena, G. A. and Angelini, G. Contact allergy to Centelase. Contact Dermatitis 1986;15(2):108-109. PubMed
  15. Marastoni, F., Baldo, A., Redaelli, G., and Ghiringhelli, L. [Centella asiatica extract in venous pathology of the lower limbs and its evaluation as compared with tribenoside]. Minerva Cardioangiol. 1982;30(4):201-207.
  16. Danese, P., Carnevali, C., and Bertazzoni, M. G. Allergic contact dermatitis due to Centella asiatica extract. Contact Dermatitis 1994;31(3):201.
  17. Bilbao, I., Aguirre, A., Zabala, R., Gonzalez, R., Raton, J., and Diaz Perez, J. L. Allergic contact dermatitis from butoxyethyl nicotinic acid and Centella asiatica extract. Contact Dermatitis 1995;33(6):435-436.
  18. Dantuluri S, North-lewis P, Karthik SV. Gotu Kola induced hepatotoxicity in a child - need for caution with alternative remedies. Dig Liver Dis. 2011;43(6):500. PubMed

See these in context on the Gotu Kola monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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