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Dietary supplement

Grapefruit Pectin 1,000 mg Ingredients & Drug Interactions

by Swanson Best Weight-Control Formulas

Grapefruit Pectin 1,000 mg label
See full label image
Tablet Or Pill Category: Fiber And Other Nutrients
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Grapefruit Pectin 1,000 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Grapefruit Pectin 1,000 mg is a dietary supplement by Swanson Best Weight-Control Formulas with 1 active ingredient. Its ingredients are commonly taken for diarrhea relief, constipation and digestive health, cholesterol support.Based on those ingredients, 23 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Grapefruit Pectin powder. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Grapefruit Pectin 1,000 mg by Swanson Best Weight-Control Formulas

Ask about any prescription or over-the-counter medication and we check it for interactions with Grapefruit Pectin 1,000 mg by Swanson Best Weight-Control Formulas — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Grapefruit Pectin 1,000 mg by Swanson Best Weight-Control Formulas

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 6, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: grapefruit pectin powder at 1,000 mg per tablet. Pectin is a natural soluble fiber extracted from citrus fruit that works by forming a gel-like substance in your digestive tract.

It's also combined with several inactive ingredients—microcrystalline cellulose, croscarmellose sodium, stearic acid, and others—that help form and stabilize the tablet.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

We hold no graded evidence for this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: weight management and appetite support.
  • We looked for evidence on: Obesity, Weight loss, Satiety.
  • Our graded evidence for these ingredients doesn't cover that particular purpose.

Grapefruit pectin is possibly effective for high cholesterol (hypercholesterolemia) based on the evidence we have on file. For prediabetes (impaired glucose tolerance) and radiation exposure, the evidence isn't established enough to rate it one way or the other.

If you're considering this for cholesterol, talk with your doctor about how it might fit into your full treatment plan.

The evidence, ingredient by ingredient Pectin

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Pectin from food and typical supplement doses is generally well tolerated. The most common side effects are mild—diarrhea, gas, loose stools, and gentle cramping.

Rare but serious allergic reactions, including anaphylaxis, can occur in people sensitive to pectin; occupational inhalation of pectin dust can also trigger asthma in susceptible individuals. For pregnancy and breastfeeding, the evidence is limited.

Pectin from food is fine, but concentrated supplements at this dose haven't been well studied in pregnancy or while nursing. Talk with your doctor or pharmacist about whether this is right for you in those situations.

Side effects, ingredient by ingredient Pectin

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Pectin.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: heart-rhythm medications.
  • For scale: 23 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, talk with your doctor or pharmacist if you take digoxin (a heart medication), lovastatin (for cholesterol), or tetracycline antibiotics. Pectin may reduce how much of these drugs your body absorbs, potentially making them less effective.

Even if your medication isn't listed, confirm it's safe to combine with this supplement.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Grapefruit pectin may help lower cholesterol, but it has Moderate-severity interactions with heart and antibiotic medications that could reduce how well they work. If you take digoxin, lovastatin, tetracycline, or any other prescription drugs, check them against this product first with your doctor or pharmacist.

Most people tolerate pectin well, though mild digestive side effects are common.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Feb 25, 2019.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Grapefruit Pectin 1,000 mg, straight from the product label.

Brand Swanson Best Weight-Control Formulas
Barcode (UPC) 087614040080
Net contents 240 Tablet(s)
Market status On market
Date entered into DSLD Feb 25, 2019
DSLD ID 188656
Product type Fiber And Other Nutrients
Supplement form Tablet Or Pill
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Grapefruit Pectin 1,000 mg by Swanson Best Weight-Control Formulas, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
3 Tablet(s)
Maximum serving Sizes:
3 Tablet(s)
Servings per container
80
UPC/BARCODE
087614040080
IngredientAmount% DV
Grapefruit Pectin powder3 Gram(s)--

Other ingredients: Microcrystalline Cellulose, Croscarmellose Sodium, Stearic Acid, Hydroxypropyl Methylcellulose, Magnesium Stearate, Pharmaceutical Glaze, Silica, Magnesium Silicate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Seals/Symbols

Guaranteed purity & potency

FDA Statement of Identity

Dietary Supplement

Precautions

Do not use if seal is broken.

Keep out of reach of children.

Storage

Store in a cool, dry place.

Suggested/Recommended/Usage/Directions

Suggested use: As a dietary supplement, take one to three tablets 15 minutes before each meal with water.

General

SWD008 Rev 2 06 14 18

General Statements

To reorder, call toll free 1-800-437-4148 or visit our website at www.swansonvitamins.com

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Grapefruit Pectin 1,000 mg by Swanson Best Weight-Control Formulas label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Grapefruit Pectin 1,000 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Grapefruit Pectin 1,000 mg by Swanson Best Weight-Control Formulas

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size3 Tablet(s) Dosage formTablet Or Pill Servings per container80 Amounts shown are per serving.

Grapefruit Pectin powder

Interacts with
23 drugs
3 Gram(s) per serving

Pectin is a natural soluble fiber found in fruits like apples and citrus, and it is widely used in foods and as a fiber supplement. It may modestly he...

Grapefruit Pectin powder monograph & interactions

Other (inactive) ingredients: Microcrystalline Cellulose, Croscarmellose Sodium, Stearic Acid, Hydroxypropyl Methylcellulose, Magnesium Stearate, Pharmaceutical Glaze, Silica, Magnesium Silicate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Grapefruit Pectin 1,000 mg by Swanson Best Weight-Control Formulas Drug Interactions

Want to check YOUR meds against Grapefruit Pectin 1,000 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
23Drugs
23 Moderate

Ingredients driving the most interactions

Grapefruit Pectin powder 23

Individual Drug Interactions

The ingredients in Grapefruit Pectin 1,000 mg interact with 23 drugs. Click any drug to see the details.

1 of the 1 ingredient in Grapefruit Pectin 1,000 mg interact with drugs. Each result below shows which ingredient is responsible. Grapefruit Pectin powder

Each ingredient & the kinds of drugs it affects

For each ingredient in Grapefruit Pectin 1,000 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Grapefruit Pectin powder3 drug types · 23 drugs

Digoxin (Lanoxin)

Theoretically, pectin might reduce the absorption of digoxin, potentially decreasing its effectiveness.
A small clinical study shows that taking digoxin with a kaolin-pectin suspension reduces the absorption of digoxin by about 62%. It is unclear if these effects are due to pectin, kaolin, or the combination.

Likelihood Possible Evidence B
Lovastatin (Mevacor)

Theoretically, pectin might reduce the absorption of lovastatin, potentially decreasing its effectiveness.
Case reports suggest that concomitant use of pectin and lovastatin might reduce the cholesterol-lowering effect of lovastatin, possibly due to reduced intestinal absorption of lovastatin.

Likelihood Possible Evidence D
Tetracycline Antibiotics

Theoretically, pectin might reduce the absorption of tetracycline antibiotics, potentially decreasing their effectiveness.
A small clinical study shows that taking tetracycline with bismuth subsalicylate in a kaolin-pectin suspension reduces the absorption of tetracycline by about 34%. It is unclear if these effects are due to pectin, kaolin, bismuth subsalicylate, or the combination.

Likelihood Possible Evidence B
Grapefruit Pectin powder full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Grapefruit Pectin 1,000 mg, from the product label.

Swanson Best Weight-Control Formulas

See all Swanson Best Weight-Control Formulas products
Name
Swanson Health Products
City
Fargo
State
ND
ZipCode
58104
Phone Number
1-800-437-4148
Web Address
www.swansonvitamins.com
Pharmacist Counseling Corner

Grapefruit Pectin 1,000 mg by Swanson Best Weight-Control Formulas: Common Questions

Does Grapefruit Pectin 1,000 mg by Swanson Best Weight-Control Formulas interact with any medications?
Yes. Based on its ingredients, Grapefruit Pectin 1,000 mg has a known interaction with 23 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Grapefruit Pectin 1,000 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this help me lose weight?
The data we have on file rates grapefruit pectin as possibly effective for lowering cholesterol, not specifically for weight loss. If weight management is your goal, talk with your doctor about whether this supplement makes sense as part of your overall plan.
What side effects should I expect?
Most people tolerate pectin well. Mild digestive side effects—diarrhea, gas, loose stools, and light cramping—are the most common. Serious allergic reactions are rare but can happen in people sensitive to pectin.
Is this safe if I'm pregnant or breastfeeding?
Pectin from food is fine during pregnancy and breastfeeding, but safety data for concentrated supplements at this dose is limited. Talk with your doctor or pharmacist about whether to take this supplement while pregnant or nursing.
Can I take this with my heart or antibiotic medications?
Pectin may reduce how much digoxin (a heart medication), lovastatin (for cholesterol), or tetracycline antibiotics your body absorbs, potentially weakening their effect. Before combining this supplement with any prescription medication, check with your doctor or pharmacist.
What is grapefruit pectin and what does it do?
Pectin is a natural soluble fiber from citrus fruit that forms a gel-like substance in your digestive tract. Research suggests it may help lower cholesterol, though evidence for other uses like blood sugar control is not yet established.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Grapefruit Pectin 1,000 mg is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Grapefruit Pectin 1,000 mg label
Go deeper

The Full Monographs Behind Grapefruit Pectin 1,000 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Pectin

Interacts with 23 drugs

Pectin is a natural soluble fiber found in fruits like apples and citrus, and it is widely used in foods and as a fiber supplement. It may modestly help with cholesterol, blood sugar, and di...

Read the full Pectin monograph →
Sources

Sources & How We Checked

Grapefruit Pectin 1,000 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 11 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Pectin 11 references
  1. Jaakkola MS, et al. Asthma caused by occupational exposure to pectin. J Allergy Clin Immunol 1997;100:575-6. PubMed
  2. Westphal W, et al. [Exogenous allergic asthma following pectin exposure-a new occupational allergen]. Pneumologie 1990;44(Suppl 1):337-8.
  3. Baldwin JL, et al. Pectin-induced occupational asthma. Chest 1993;104:1936-7. PubMed
  4. Cohen AJ, Forse MS, Tarlo SM. Occupational asthma caused by pectin inhalation during the manufacture of jam. Chest 1993;103:309-11.
  5. Kraut A, et al. Christmas candy maker's asthma. IgG4-mediated pectin allergy. Chest 1992;102:1605-7. PubMed
  6. Richter WO, Jacob BG, Schwandt P. Interaction between fibre and lovastatin. Lancet 1991;338:706.
  7. Albert KS, Ayres JW, DiSanto AR, et al. Influence of kaolin-pectin suspension on digoxin bioavailability. J Pharm Sci 1978;67:1582-6. PubMed
  8. Albert KS, Welch RD, DeSante KA, et al. Decreased tetracycline bioavailability caused by a bismuth subsalicylate antidiarrheal mixture. J Pharm Sci 1979;68:586-8. PubMed
  9. Electronic Code of Federal Regulations. Title 21. Part 182 -- Substances Generally Recognized As Safe. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182
  10. Federal Register April 17,2003. Anti-Diarrheal Products for over-the-counter human use; final monograph. Available at: http://www.fda.gov/OHRMS/DOCKETS/98fr/03-9380.pdf (Accessed 27 December 2004).
  11. Washio K, Nakamura M, Sato N, et al. Anaphylaxis in a pectin- and cashew nut-allergic child caused by a citrus bath. Allergol Int 2022;71(1):155-157. PubMed

See these in context on the Pectin monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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