Gua Lou Ingredients & Drug Interactions
by Herbal Terra
What is this page for?
First and foremost: checking Gua Lou against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Gua Lou is a dietary supplement by Herbal Terra with 1 active ingredient. Its ingredients are commonly taken for cough and chest congestion, constipation, diabetes (traditional use).Based on those ingredients, 86 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Trichosanthes kirilowii Fruit Extract, Dry. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Gua Lou by Herbal Terra
Ask about any prescription or over-the-counter medication and we check it for interactions with Gua Lou by Herbal Terra — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Gua Lou by Herbal Terra
Four independent checks of what is known — a summary of the available information, not a grade of the product itself.
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
The stated purpose hasn't been mapped to our evidence data yet.
Why this rating?
- We haven't mapped this product's purpose to our evidence data yet — it'll be graded on the next content refresh.
Every active ingredient lists its own amount on the label.
Why this rating?
- The label discloses an exact amount for 1 of its 1 active ingredient.
- No proprietary blends here — you can verify the dose of every single component.
The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.
Why this rating?
- 1 of the 1 matched ingredient can interact with medications — Chinese Cucumber.
- The most serious interaction on file is rated Moderate.
- Some involve high-stakes drug classes: diabetes medications.
- For scale: 86 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.
Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.
Why this rating?
- We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
- Pregnancy & breastfeeding safety ratings cover 1 of 1.
- General safety write-ups exist for 1 of 1.
- Remember: this measures how much safety information exists. Thin data is not the same as being safe.
HelloPharmacist summaryFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Mar 25, 2025.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Gua Lou, straight from the product label.
| Brand | Herbal Terra |
|---|---|
| Barcode (UPC) | 7238360205398 |
| Net contents | 2 Fluid Ounce(s); 60 mL |
| Market status | On market |
| Date entered into DSLD | Mar 25, 2025 |
| DSLD ID | 325074 |
| Product type | Botanical |
| Supplement form | Liquid |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free, Sugar Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Gua Lou by Herbal Terra, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Trichosanthes kirilowii Fruit Extract, Dry | 983 mg | -- |
Other ingredients: Alcohol, Water, Glycerin
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Shake well before use. Adults take up to 30 drops (1 mL, one full squeeze of the dropper bulb) in 3-4 fl. oz. of juice or water up to 4 times a day.
Precautions
We recommend to seek expert medical advice before taking. May have contraindications and cause adverse reaction.
Consult a physician before giving to children under 18, before using during pregnancy, if nursing, or if you are on any medications.
Consult a physician before giving to children under 18, before using during pregnancy, if nursing, or if you are on any medications. Keep out of the reach of children!
Do not use if you are allergic to any ingredients.
Storage
Store in a cool, dry, dark place.
FDA Disclaimer Statement
This product has not been evaluated by the FDA and is not intended to diagnose, treat, cure or prevent any disease.
Formulation
cGMP Made in compliance with cGMP 21 CFR 111 in an FDA registered and inspected facility.
Sugar free
Expertly extracted 100% natural Premium product
Organic alcohol
No artificial ingredients, color additives, fillers or binders.
Natural Gluten free
Formula
Trichosanthes kirilowii
Organic alcohol
FDA Statement of Identity
Herbal Supplement
Seals/Symbols
Made in USA
General Statements
Organic raw material.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Gua Lou by Herbal Terra label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Gua Lou by Herbal Terra
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 mL Dosage formLiquid Servings per container60 Amounts shown are per serving.
Trichosanthes kirilowii Fruit Extract, Dry
Interacts with86 drugs
Chinese cucumber (Trichosanthes kirilowii) is a plant used in traditional Chinese medicine, and a protein from its root called trichosanthin (Compound...
Trichosanthes kirilowii Fruit Extract, Dry monograph & interactionsOther (inactive) ingredients: Alcohol, Water, Glycerin. These complete the product’s ingredient list but are not active constituents.
Gua Lou by Herbal Terra Drug Interactions
Gua Lou contains a single active ingredient, and it has known interactions with 86 medications. Here’s the picture, then you can look up your own drug.
Want to check YOUR meds against Gua Lou?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Gua Lou interact with 86 drugs. Click any drug to see the details.
1 of the 1 ingredient in Gua Lou interact with drugs. Each result below shows which ingredient is responsible. Trichosanthes kirilowii Fruit Extract, Dry
Metformin XrGlucophage XR
How Metformin Xr interacts with Gua Lou — through 1 ingredient. Tap an ingredient for the detail:
Trichosanthes Kirilowii Fruit Extract, DryAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, concomitant use of Chinese cucumber with antidiabetic drugs may have additive effects and adverse effects.
Read the full Trichosanthes Kirilowii Fruit Extract, Dry + Metformin Xr interactionMetformin, LinagliptinJentadueto
How Metformin, Linagliptin interacts with Gua Lou — through 1 ingredient. Tap an ingredient for the detail:
Trichosanthes Kirilowii Fruit Extract, DryAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, concomitant use of Chinese cucumber with antidiabetic drugs may have additive effects and adverse effects.
Read the full Trichosanthes Kirilowii Fruit Extract, Dry + Metformin, Linagliptin interactionMetformin, RosiglitazoneAvandamet
How Metformin, Rosiglitazone interacts with Gua Lou — through 1 ingredient. Tap an ingredient for the detail:
Trichosanthes Kirilowii Fruit Extract, DryAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, concomitant use of Chinese cucumber with antidiabetic drugs may have additive effects and adverse effects.
Read the full Trichosanthes Kirilowii Fruit Extract, Dry + Metformin, Rosiglitazone interactionMetformin, SitagliptinJanumet, Janumet XR
How Metformin, Sitagliptin interacts with Gua Lou — through 1 ingredient. Tap an ingredient for the detail:
Trichosanthes Kirilowii Fruit Extract, DryAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, concomitant use of Chinese cucumber with antidiabetic drugs may have additive effects and adverse effects.
Read the full Trichosanthes Kirilowii Fruit Extract, Dry + Metformin, Sitagliptin interactionMiglitolGlyset
How Miglitol interacts with Gua Lou — through 1 ingredient. Tap an ingredient for the detail:
Trichosanthes Kirilowii Fruit Extract, DryAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, concomitant use of Chinese cucumber with antidiabetic drugs may have additive effects and adverse effects.
Read the full Trichosanthes Kirilowii Fruit Extract, Dry + Miglitol interactionMuraglitazarPargluva
How Muraglitazar interacts with Gua Lou — through 1 ingredient. Tap an ingredient for the detail:
Trichosanthes Kirilowii Fruit Extract, DryAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, concomitant use of Chinese cucumber with antidiabetic drugs may have additive effects and adverse effects.
Read the full Trichosanthes Kirilowii Fruit Extract, Dry + Muraglitazar interactionNateglinideStarlix
How Nateglinide interacts with Gua Lou — through 1 ingredient. Tap an ingredient for the detail:
Trichosanthes Kirilowii Fruit Extract, DryAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, concomitant use of Chinese cucumber with antidiabetic drugs may have additive effects and adverse effects.
Read the full Trichosanthes Kirilowii Fruit Extract, Dry + Nateglinide interactionPioglitazoneActos
How Pioglitazone interacts with Gua Lou — through 1 ingredient. Tap an ingredient for the detail:
Trichosanthes Kirilowii Fruit Extract, DryAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, concomitant use of Chinese cucumber with antidiabetic drugs may have additive effects and adverse effects.
Read the full Trichosanthes Kirilowii Fruit Extract, Dry + Pioglitazone interactionPramlintideSymlin
How Pramlintide interacts with Gua Lou — through 1 ingredient. Tap an ingredient for the detail:
Trichosanthes Kirilowii Fruit Extract, DryAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, concomitant use of Chinese cucumber with antidiabetic drugs may have additive effects and adverse effects.
Read the full Trichosanthes Kirilowii Fruit Extract, Dry + Pramlintide interactionRepaglinideGlucoNorm, Prandin
How Repaglinide interacts with Gua Lou — through 1 ingredient. Tap an ingredient for the detail:
Trichosanthes Kirilowii Fruit Extract, DryAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, concomitant use of Chinese cucumber with antidiabetic drugs may have additive effects and adverse effects.
Read the full Trichosanthes Kirilowii Fruit Extract, Dry + Repaglinide interactionRosiglitazone MaleateAvandia
How Rosiglitazone Maleate interacts with Gua Lou — through 1 ingredient. Tap an ingredient for the detail:
Trichosanthes Kirilowii Fruit Extract, DryAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, concomitant use of Chinese cucumber with antidiabetic drugs may have additive effects and adverse effects.
Read the full Trichosanthes Kirilowii Fruit Extract, Dry + Rosiglitazone Maleate interactionSaxagliptinOnglyza
How Saxagliptin interacts with Gua Lou — through 1 ingredient. Tap an ingredient for the detail:
Trichosanthes Kirilowii Fruit Extract, DryAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, concomitant use of Chinese cucumber with antidiabetic drugs may have additive effects and adverse effects.
Read the full Trichosanthes Kirilowii Fruit Extract, Dry + Saxagliptin interactionSaxagliptin, Metformin XrKombiglyze
How Saxagliptin, Metformin Xr interacts with Gua Lou — through 1 ingredient. Tap an ingredient for the detail:
Trichosanthes Kirilowii Fruit Extract, DryAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, concomitant use of Chinese cucumber with antidiabetic drugs may have additive effects and adverse effects.
Read the full Trichosanthes Kirilowii Fruit Extract, Dry + Saxagliptin, Metformin Xr interactionSemaglutideOzempic, Rybelsus, Wegovy
How Semaglutide interacts with Gua Lou — through 1 ingredient. Tap an ingredient for the detail:
Trichosanthes Kirilowii Fruit Extract, DryAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, concomitant use of Chinese cucumber with antidiabetic drugs may have additive effects and adverse effects.
Read the full Trichosanthes Kirilowii Fruit Extract, Dry + Semaglutide interactionSimvastatin, SitagliptinJuvisync
How Simvastatin, Sitagliptin interacts with Gua Lou — through 1 ingredient. Tap an ingredient for the detail:
Trichosanthes Kirilowii Fruit Extract, DryAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, concomitant use of Chinese cucumber with antidiabetic drugs may have additive effects and adverse effects.
Read the full Trichosanthes Kirilowii Fruit Extract, Dry + Simvastatin, Sitagliptin interactionSitagliptinJanuvia, Zituvio
How Sitagliptin interacts with Gua Lou — through 1 ingredient. Tap an ingredient for the detail:
Trichosanthes Kirilowii Fruit Extract, DryAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, concomitant use of Chinese cucumber with antidiabetic drugs may have additive effects and adverse effects.
Read the full Trichosanthes Kirilowii Fruit Extract, Dry + Sitagliptin interactionSitagliptin, MetforminZituvimet
How Sitagliptin, Metformin interacts with Gua Lou — through 1 ingredient. Tap an ingredient for the detail:
Trichosanthes Kirilowii Fruit Extract, DryAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, concomitant use of Chinese cucumber with antidiabetic drugs may have additive effects and adverse effects.
Read the full Trichosanthes Kirilowii Fruit Extract, Dry + Sitagliptin, Metformin interactionSotagliflozinInpefa
How Sotagliflozin interacts with Gua Lou — through 1 ingredient. Tap an ingredient for the detail:
Trichosanthes Kirilowii Fruit Extract, DryAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, concomitant use of Chinese cucumber with antidiabetic drugs may have additive effects and adverse effects.
Read the full Trichosanthes Kirilowii Fruit Extract, Dry + Sotagliflozin interactionTirzepatideMounjaro, Zepbound
How Tirzepatide interacts with Gua Lou — through 1 ingredient. Tap an ingredient for the detail:
Trichosanthes Kirilowii Fruit Extract, DryAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, concomitant use of Chinese cucumber with antidiabetic drugs may have additive effects and adverse effects.
Read the full Trichosanthes Kirilowii Fruit Extract, Dry + Tirzepatide interactionTobutamideMobenol
How Tobutamide interacts with Gua Lou — through 1 ingredient. Tap an ingredient for the detail:
Trichosanthes Kirilowii Fruit Extract, DryAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, concomitant use of Chinese cucumber with antidiabetic drugs may have additive effects and adverse effects.
Read the full Trichosanthes Kirilowii Fruit Extract, Dry + Tobutamide interactionTolazamideTolinase
How Tolazamide interacts with Gua Lou — through 1 ingredient. Tap an ingredient for the detail:
Trichosanthes Kirilowii Fruit Extract, DryAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, concomitant use of Chinese cucumber with antidiabetic drugs may have additive effects and adverse effects.
Read the full Trichosanthes Kirilowii Fruit Extract, Dry + Tolazamide interactionTolbutamideOrinase
How Tolbutamide interacts with Gua Lou — through 1 ingredient. Tap an ingredient for the detail:
Trichosanthes Kirilowii Fruit Extract, DryAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, concomitant use of Chinese cucumber with antidiabetic drugs may have additive effects and adverse effects.
Read the full Trichosanthes Kirilowii Fruit Extract, Dry + Tolbutamide interactionTroglitazoneRezulin
How Troglitazone interacts with Gua Lou — through 1 ingredient. Tap an ingredient for the detail:
Trichosanthes Kirilowii Fruit Extract, DryAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, concomitant use of Chinese cucumber with antidiabetic drugs may have additive effects and adverse effects.
Read the full Trichosanthes Kirilowii Fruit Extract, Dry + Troglitazone interactionVildagliptinGalvus
How Vildagliptin interacts with Gua Lou — through 1 ingredient. Tap an ingredient for the detail:
Trichosanthes Kirilowii Fruit Extract, DryAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, concomitant use of Chinese cucumber with antidiabetic drugs may have additive effects and adverse effects.
Read the full Trichosanthes Kirilowii Fruit Extract, Dry + Vildagliptin interactionPioglitazone, MetforminActoPlus Met
How Pioglitazone, Metformin interacts with Gua Lou — through 1 ingredient. Tap an ingredient for the detail:
Trichosanthes Kirilowii Fruit Extract, DryAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, concomitant use of Chinese cucumber with antidiabetic drugs may have additive effects and adverse effects.
Read the full Trichosanthes Kirilowii Fruit Extract, Dry + Pioglitazone, Metformin interactionRosiglitazone, GlimepirideAvandaryl
How Rosiglitazone, Glimepiride interacts with Gua Lou — through 1 ingredient. Tap an ingredient for the detail:
Trichosanthes Kirilowii Fruit Extract, DryAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, concomitant use of Chinese cucumber with antidiabetic drugs may have additive effects and adverse effects.
Read the full Trichosanthes Kirilowii Fruit Extract, Dry + Rosiglitazone, Glimepiride interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Gua Lou with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Trichosanthes kirilowii Fruit Extract, Dry
Antidiabetes Drugs
Theoretically, concomitant use of Chinese cucumber with antidiabetic drugs may have additive effects and adverse effects. Monitor blood glucose levels closely, dose adjustment may be needed.
Brand information
Manufacturer and brand details for Gua Lou, from the product label.
Herbal Terra
See all Herbal Terra products- Name
- Herbal Terra LLC
- Phone Number
- +18083857868
- Web Address
- herbalterra.com
Gua Lou by Herbal Terra: Common Questions
Does Gua Lou by Herbal Terra interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Gua Lou is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Gua Lou’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Gua Lou's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 4 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Chinese Cucumber 4 references
- The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
- McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
- Hikino H, Yoshizawa M, Suzuki Y, et al. Isolation and hypoglycemic activity of trichosans A, B, C, D, and E: glycans of Trichosanthes kirilowii roots. Planta Med 1989;55:349-50.
- Jung YB, Roh KJ, Jung JA, et al. Effect of SKI 306X, a new herbal anti-arthritic agent, in patients with osteoarthritis of the knee: a double-blind placebo controlled study. Am J Chin Med. 2001;29(3-4):485-91. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC