Interactions on record — worth a quick check against your medications. Based on 9 of 14 ingredients. Check your meds →
Dietary supplement

Quiet Digestion Ingredients & Drug Interactions

by Health Concerns

Quiet Digestion label
See full label image
Tablet Or Pill Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Quiet Digestion against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Quiet Digestion is a dietary supplement by Health Concerns with 14 active ingredients. Its ingredients are commonly taken for general wellness and longevity, antioxidant support, heart and cholesterol health.Based on those ingredients, 1,274 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Red Atractylodes, Pueraria, Poria sclerotium. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Quiet Digestion by Health Concerns

Ask about any prescription or over-the-counter medication and we check it for interactions with Quiet Digestion by Health Concerns — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Quiet Digestion by Health Concerns

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 14 active ingredients.
  • “Proprietary Blend” is a proprietary blend — the label gives one combined amount (1,500 mg) without saying how much of each component you get.

Quiet Digestion has 14 active and inactive ingredients, including a proprietary blend. The active components include Poria mushroom, Magnolia, Red Atractylodes, Coix (Job's tears), Pueraria (kudzu), Barley Shen Qu leaven, Chrysanthemum, and several other plant-derived ingredients — Vladimiria Souliei, Oryza, Angelica, Pogostemon, and Trichosanthes — whose specific roles we don't have data on.

The inactive ingredients are vegetable gum, silicon dioxide, stearic acid, and cellulose, which help bind and stabilize the tablet.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: digestive health and comfort support.
  • We looked for evidence on: Abdominal pain, Anxiety, Diarrhea, Gastritis, Headache, Insomnia — and 4 related terms.
  • The closest evidence on file: Magnolia is rated "Insufficient Reliable Evidence To Rate" for Anxiety (Natural Medicines).
  • Also on file: Magnolia is rated "Insufficient Reliable Evidence To Rate" for Headache, Stress.
  • Also on file: Poria Mushroom is rated "Insufficient Reliable Evidence To Rate" for Diarrhea, Insomnia.

The evidence for Quiet Digestion's ingredients varies. Barley has the strongest rating — it's Likely Effective for high cholesterol and heart-disease risk reduction.

Magnolia is Possibly Effective for gingivitis. For most other conditions listed — such as anxiety, dementia, diabetes, diarrhea, and common cold — the ingredients are rated Insufficient Reliable Evidence, meaning we don't have enough quality study data to know if they work.

Pueraria (kudzu) is Possibly Effective for alcohol-use disorder, but again, data on most of its other uses are insufficient.

The evidence, ingredient by ingredient Ashitaba Poria Mushroom Magnolia Atractylodes Job's Tears Chinese Cucumber Kudzu Chrysanthemum

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 7 of the 9 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 9 of 9.
  • General safety write-ups exist for 9 of 9.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Several ingredients carry important safety cautions. Magnolia is Unsafe in pregnancy and should be avoided while breastfeeding.

Poria mushroom and Red Atractylodes are best avoided during pregnancy due to insufficient safety data, and both lack reliable breastfeeding data. Pueraria (kudzu) is also best avoided in pregnancy and while breastfeeding.

Chrysanthemum is generally well tolerated as a tea but can trigger allergic reactions in sensitive people and is best avoided in pregnancy and breastfeeding unless a doctor approves. Barley is safe as a normal food but contains gluten.

Rare allergic reactions — including urticaria, contact dermatitis, and in isolated cases asthma — have been reported with some ingredients. A small number of people taking combination products containing magnolia reported sexual dysfunction, shaking, numbness, fatigue, and headache, though it's unclear if magnolia was responsible.

Side effects, ingredient by ingredient Ashitaba Poria Mushroom Magnolia Atractylodes Job's Tears Chinese Cucumber Kudzu Chrysanthemum

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 8 of the 9 matched ingredients can interact with medications — Chinese Cucumber, Magnolia, Poria Mushroom, Kudzu, Barley, among others.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications.
  • For scale: 1,275 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check your medications against this product before taking it if you use anticoagulants or antiplatelet drugs (blood thinners) — Magnolia, Pueraria, and Red Atractylodes may increase bleeding risk. Also ask about antidiabetes drugs, sedatives, heart medications like diltiazem, theophylline (for breathing), methotrexate, tamoxifen, estrogen therapy, and caffeine supplements.

A full list of the 1,253 affected medications is searchable with the tool below.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

Quiet Digestion is designed to support digestive comfort using traditional plant ingredients, but it carries documented interactions with multiple medication types — especially blood thinners, diabetes drugs, sedatives, and certain cancer medications. If you take any prescription medication, use the checker on this page to confirm your drugs aren't affected before you start.

Talk to your pharmacist or doctor if you're pregnant, breastfeeding, or have liver concerns.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 9 of 14 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2013.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Quiet Digestion, straight from the product label.

Brand Health Concerns
Net contents 270 Tablet(s)
Market status Off market
Date entered into DSLD Sep 25, 2013
DSLD ID 25709
Product type Other Combinations
Supplement form Tablet Or Pill
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Quiet Digestion by Health Concerns, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Tablet(s)
Maximum serving Sizes:
2 Tablet(s)
Servings per container
135
IngredientAmount% DV
Proprietary Blend1500 mg--
Vladimiria Souliei0 Not Present--
Oryza0 Not Present--
Angelica0 Not Present--
Poria sclerotium0 Not Present--
Magnolia0 Not Present--
Pogostemon0 Not Present--
Red Atractylodes0 Not Present--
Coix0 Not Present--
Trichosanthes0 Not Present--
Pueraria0 Not Present--
Chrysanthemum0 Not Present--
Halloysite mineral0 Not Present--
Red Citrus0 Not Present--
Barley Shen Qu leaven0 Not Present--

Other ingredients: Vegetable Gum, Silicon Dioxide, Stearic Acid, Cellulose

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested Use: Two tablets 3 times per day between meals or 2 tablets with meals.

Precautions

Notice: This product is not intended for use by pregnant women.

General Statements

Made in the U.S.A.

Pin Yin: Fu Ling, Yi Yi Ren, Shen Qu, Hou Po, Bai Zhi, Ge Gen, Cang Zhu, Mu Xiang, Huo Xiang, Gu Ya, Tian Hua Fen, Ju Hua, Chi Shi Zhi, Ju Hong.

Brand IP Statement(s)

CHINESE TRADITIONAL FORMULAS(TM)

COMBINING MODERN RESEARCH AND ANCIENT WISDOM(R)

FDA Statement of Identity

Curing Herbal Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Quiet Digestion by Health Concerns label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Quiet Digestion label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Quiet Digestion by Health Concerns

These are the 14 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Tablet(s) Dosage formTablet Or Pill Servings per container135 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Proprietary Blend

1500 mg per serving

Other (inactive) ingredients: Vegetable Gum, Silicon Dioxide, Stearic Acid, Cellulose. These complete the product’s ingredient list but are not active constituents.

Interaction report

Quiet Digestion by Health Concerns Drug Interactions

Want to check YOUR meds against Quiet Digestion?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
1,274Drugs
974 Moderate 300 Minor

Ingredients driving the most interactions

Red Atractylodes 801
Pueraria 584
Poria sclerotium 417
Magnolia 351
Angelica 186

Individual Drug Interactions

The ingredients in Quiet Digestion interact with 1,274 drugs. Click any drug to see the details.

8 of the 14 ingredients in Quiet Digestion interact with drugs. Each result below shows which ingredient is responsible. Red Atractylodes Pueraria Poria sclerotium Magnolia Angelica Coix Trichosanthes Barley Shen Qu leaven

Each ingredient & the kinds of drugs it affects

For each ingredient in Quiet Digestion with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Red Atractylodes5 drug types · 801 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, atractylodes might increase the risk of bleeding when used concomitantly with anticoagulant and antiplatelet drugs.
Laboratory research suggests that atractylenolides II and III, constituents of atractylodes, reduce platelet activation. So far, this has not been shown in humans.

Likelihood Possible Evidence D
Aromatase Inhibitors

Theoretically, atractylodes may have an additive effect when used with other aromatase inhibitors.
Laboratory research suggests that atractylodes and its constituents exhibit aromatase inhibitor effects.

Likelihood Possible Evidence D
Hexobarbital

Theoretically, taking atractylodes may prolong the therapeutic and adverse effects of hexobarbital.
In animals, atractylodes has been shown to prolong the effects of hexobarbital. These effects have not been shown in humans.

Likelihood Possible Evidence D
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, atractylodes might decrease the levels of CYP1A2 substrates.
In animals, atractylodes administered at high doses has been shown to induce CYP1A2 activity. This effect has not been shown in humans.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, atractylodes might increase the levels of CYP3A4 substrates.
In animals, atractylodes administered at high doses has been shown to inhibit CYP3A1 activity, which is a homolog to the human CYP3A4 enzyme. This effect has not been shown in humans.

Likelihood Possible Evidence D
Red Atractylodes full monograph & interactions

Pueraria7 drug types · 584 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, kudzu may increase the risk of bleeding if used with antiplatelet or anticoagulant drugs.
Kudzu isoflavones are reported to have antiplatelet activity.

Likelihood Possible Evidence D
Caffeine

Theoretically, taking kudzu with caffeine might increase levels of caffeine.
In healthy males injected with the kudzu constituent puerarin, caffeine clearance and metabolism is inhibited. This effect has been attributed to inhibition of cytochrome P450 1A2 (CYP1A2) enzyme, which is involved in caffeine metabolism. It is unclear if taking kudzu orally would have this same effect.

Likelihood Probable Evidence D
Estrogens

Theoretically, kudzu might alter the effects of estrogen therapy.
Some research suggests that kudzu has estrogenic effects. This may enhance or inhibit the effects of estrogen therapy.

Likelihood Possible Evidence B
Hepatotoxic Drugs

Theoretically, concomitant use might have additive hepatotoxic effects.
There is some concern that kudzu can adversely affect the liver.

Likelihood Possible Evidence D
Methotrexate (Trexall, Others)

Theoretically, taking kudzu with methotrexate might increase the risk of methotrexate toxicity.
Preclinical research suggests that kudzu extract greatly reduces the elimination and increases the toxicity of methotrexate. Kudzu might inhibit organic anion transporters (OATs) that are responsible for hepatobiliary and renal excretion of anions, similar to the interaction between methotrexate and non-steroidal anti-inflammatory drugs (NSAIDs).

Likelihood Possible Evidence D
Tamoxifen (Nolvadex)

Theoretically, kudzu might interfere with tamoxifen activity.
Some research suggests that kudzu may have estrogenic effects.

Likelihood Possible Evidence B
Antidiabetes Drugs

Theoretically, taking kudzu with antidiabetes drugs might increase the risk of hypoglycemia.
Kudzu might lower blood glucose levels and have additive effects in patients treated with antidiabetic agents. The dose of diabetes medications might need to be adjusted.

Likelihood Unlikely Evidence D
Pueraria full monograph & interactions

Poria sclerotium3 drug types · 417 drugs

Anticholinergic Drugs

Theoretically, poria mushroom might decrease the clinical effects of anticholinergic drugs.
In animal research, poria mushroom essential oil reduces acetylcholinesterase activity. This interaction has not been shown in humans.

Likelihood Possible Evidence D
Cholinergic Drugs

Theoretically, poria mushroom might have additive effects when used with cholinergic drugs.
In animal research, poria mushroom essential oil reduces acetylcholinesterase activity. This interaction has not been shown in humans.

Likelihood Possible Evidence D
Cns Depressants

Theoretically, taking poria mushroom extract may enhance the therapeutic and adverse effects of sedatives.
Animal research shows that poria mushroom extract has sedative properties. This interaction has not been shown in humans.

Likelihood Possible Evidence D
Poria sclerotium full monograph & interactions

Magnolia2 drug types · 351 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, magnolia might have additive effects and increase the risk of bleeding when used with anticoagulant or antiplatelet drugs.
In vitro research shows that the chemicals magnolol and honokiol, isolated from magnolia bark, inhibit platelet aggregation that is experimentally induced by collagen and arachidonic acid. However, they do not inhibit platelet aggregation that is induced by adenosine diphosphate, platelet-activating factor, or thrombin. This interaction has not been reported in humans.

Likelihood Possible Evidence D
Cns Depressants

Theoretically, concomitant use of large doses of magnolia bark and CNS depressants might have additive effects.
In vitro and animal research shows that constituents extracted from magnolia bark, especially honokiol and magnolol, have sedative effects. These effects may be due to the inhibition of catecholamine release and modulation of gamma-aminobutyric acid-A (GABA-A) receptors.

Likelihood Possible Evidence D
Magnolia full monograph & interactions

Angelica1 drug type · 186 drugs

Cytochrome P450 1A2 (Cyp1A2) Substrates

In vitro research shows that ashitaba extract inhibits cytochrome P450 (CYP) 1A2. Theoretically, concomitant use of ashitaba with CYP1A2 substrates might decrease the clearance of these substrates and increase the risk for adverse effects. However, this interaction has yet to be reported in humans. Until more is known, use with caution.

Likelihood Possible Evidence D
Angelica full monograph & interactions

Coix5 drug types · 128 drugs

Antidiabetes Drugs

Preliminary evidence shows that constituents of Job's tears might have hypoglycemic effects. Theoretically, concomitant use with drugs that decrease blood glucose levels might increase the risk of hypoglycemia. Some antidiabetes drugs include glimepiride (Amaryl), glyburide (DiaBeta, Glynase PresTab, Micronase), insulin, pioglitazone (Actos), rosiglitazone (Avandia), chlorpropamide (Diabinese), glipizide (Glucotrol), tolbutamide (Orinase), and others.

Likelihood Possible Evidence D
Chlorzoxazone (Parafon Forte, Paraflex)

Animal research suggests that Job's tears might enhance absorption of chlorzoxazone in the small intestine. Single dose and short-term oral administration of Job's tears bran ethanolic extract along with oral administration of a five-drug cocktail containing chlorzoxazone increases chlorzoxazone peak plasma concentration and area under the plasma concentration-time curve (AUC) without altering major cytochrome P450 activities in the liver. This effect has not been reported in humans.

Likelihood Possible Evidence D
Dextromethorphan (Robitussin Dm, Others)

Animal research suggests that Job's tears might enhance absorption of dextromethorphan in the small intestine. Single dose oral administration of Job's tears bran ethanolic extract along with oral administration of a five-drug cocktail containing dextromethorphan increases dextromethorphan area under the plasma concentration-time curve (AUC) without altering major cytochrome P450 activities in the liver. This effect has not been reported in humans.

Likelihood Possible Evidence D
Diltiazem (Cardizem, Others)

Animal research suggests that Job's tears might enhance absorption of diltiazem in the small intestine. Single dose oral administration of Job's tears bran ethanolic extract along with oral administration of a five-drug cocktail containing diltiazem increases diltiazem peak plasma concentration and area under the plasma concentration-time curve (AUC) without altering major cytochrome P450 activities in the liver. This effect has not been reported in humans.

Likelihood Possible Evidence D
Theophylline

Animal research suggests that Job's tears might enhance absorption of theophylline in the small intestine. Single dose and short-term oral administration of Job's tears bran ethanolic extract along with oral administration of a five-drug cocktail containing theophylline increases theophylline peak plasma concentration and area under the plasma concentration-time curve (AUC) without altering major cytochrome P450 activities in the liver. This effect has not been reported in humans.

Likelihood Possible Evidence D
Coix full monograph & interactions

Trichosanthes1 drug type · 86 drugs

Antidiabetes Drugs

Theoretically, concomitant use of Chinese cucumber with antidiabetic drugs may have additive effects and adverse effects. Monitor blood glucose levels closely, dose adjustment may be needed.

Likelihood Possible Evidence D
Trichosanthes full monograph & interactions

Barley Shen Qu leaven1 drug type · 1 drug

Triclabendazole (Egaten)

Theoretically, barley might decrease the clinical effects of triclabendazole.
Animal research suggests that a diet supplemented with barley can reduce the bioavailability of triclabendazole when taken concomitantly. This effect has not been shown in humans.

Likelihood Possible Evidence D
Barley Shen Qu leaven full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Quiet Digestion, from the product label.

Health Concerns

See all Health Concerns products
Name
Health Concerns
Street Address
8001 Capwell Drive
City
Oakland
State
CA
ZipCode
94621
Pharmacist Counseling Corner

Quiet Digestion by Health Concerns: Common Questions

Does Quiet Digestion by Health Concerns interact with any medications?
Yes. Based on its ingredients, Quiet Digestion has a known interaction with 1,274 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Quiet Digestion contains 14 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is Quiet Digestion safe during pregnancy?
No. Magnolia is rated Unsafe, and Poria mushroom, Red Atractylodes, and Pueraria (kudzu) are best avoided because there isn't enough safety data. Chrysanthemum safety in pregnancy hasn't been established. Talk with your doctor or pharmacist before taking this product if you're pregnant or planning to become pregnant.
Can I take Quiet Digestion while breastfeeding?
We don't have enough reliable safety data for most of these ingredients while breastfeeding. Magnolia, Poria, Pueraria, and Chrysanthemum are all best avoided, and Red Atractylodes safety is unknown. Chat with your doctor or pharmacist to decide what's best for you and your baby.
Does Quiet Digestion actually help digestion?
The evidence varies by ingredient. We don't have strong study data showing that most of the herbs in this product improve digestion — the data are rated Insufficient. Barley does have good evidence for lowering cholesterol and heart-disease risk, but that's a different benefit.
What's in the proprietary blend, and why isn't it fully listed?
A proprietary blend lets the brand keep its exact recipe secret, so you see the ingredient names but not the individual amounts. The ingredients it contains are listed separately on the label.
Does Quiet Digestion contain gluten?
Barley is one of the active ingredients, and barley contains gluten. If you have celiac disease or gluten sensitivity, this product may not be right for you — check with your pharmacist or doctor.
Are there any common side effects?
Most ingredients are generally well tolerated. The main risks are rare allergic reactions — some people report urticaria, contact dermatitis, or asthma with chrysanthemum. Nausea, dry mouth, and bloating have been reported with a few ingredients in clinical trials, though these didn't happen more often than placebo.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Quiet Digestion label
Go deeper

The Full Monographs Behind Quiet Digestion’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Ashitaba

Interacts with 186 drugs

Ashitaba is a leafy plant from Japan that is eaten as a vegetable and taken as a supplement for general health, antioxidant, and heart benefits. Most of the supporting research comes from la...

Read the full Ashitaba monograph → Herb & supplement monograph

Poria Mushroom

Interacts with 417 drugs

Poria mushroom (Fu Ling) is a fungus long used in Traditional Chinese Medicine, mainly as a mild diuretic and digestive and calming aid. Modern scientific evidence in humans is very limited,...

Read the full Poria Mushroom monograph → Herb & supplement monograph

Magnolia

Interacts with 351 drugs

Magnolia bark and flower buds have a long history in traditional Chinese and Japanese medicine, often for stress, sleep, and digestion. Modern human research is still limited, so we can't be...

Read the full Magnolia monograph → Herb & supplement monograph

Atractylodes

Interacts with 801 drugs

Atractylodes is a root used for centuries in traditional Chinese, Japanese, and Thai medicine, mostly for digestive complaints and fatigue, often as part of multi-herb formulas. Modern resea...

Read the full Atractylodes monograph → Herb & supplement monograph

Job's Tears

Interacts with 128 drugs

Job's Tears is a grain-like seed long used as a food and in traditional medicine, especially in East Asia. While it is generally safe as a food and is being studied for possible effects on m...

Read the full Job's Tears monograph → Herb & supplement monograph

Chinese Cucumber

Interacts with 86 drugs

Chinese cucumber (Trichosanthes kirilowii) is a plant used in traditional Chinese medicine, and a protein from its root called trichosanthin (Compound Q) has been studied as an injectable dr...

Read the full Chinese Cucumber monograph → Herb & supplement monograph

Kudzu

Interacts with 584 drugs

Kudzu is a fast-growing vine whose root has long been used in traditional Chinese medicine and is now studied mostly for reducing alcohol intake. Early research is promising for cutting back...

Read the full Kudzu monograph → Herb & supplement monograph

Chrysanthemum

Chrysanthemum flowers are most often used as a soothing tea in traditional Chinese medicine and as a folk remedy for eye irritation, colds, and minor inflammation. Solid human evidence for t...

Read the full Chrysanthemum monograph → Herb & supplement monograph

Barley

Interacts with 1 drug

Barley is a nutritious whole grain that is a good source of soluble fiber called beta-glucan, which has solid evidence for modestly lowering LDL ('bad') cholesterol when eaten regularly. It...

Read the full Barley monograph →
Sources

Sources & How We Checked

Quiet Digestion's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 88 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Ashitaba 2 references
  1. Kwon D, Yoon S, Carter O, Bailey GS, Dashwood RH. Antioxidant and antigenotoxic activities of Angelica keiskei, Oenanthe javanica and Brassica oleracea in the Salmonella mutagenicity assay and in HCT116 human colon cancer cells. Biofactors. 2006;26(4):231
  2. Noh HM, Ahn EM, Yun JM, Cho BL, Paek YJ. Angelica keiskei Koidzumi extracts improve some markers of liver function in habitual alcohol drinkers: a randomized double-blind clinical trial. J Med Food. 2015;18(2):166-72.

See these in context on the Ashitaba monograph →

Poria Mushroom 3 references
  1. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  2. Kim H, Park I, Park K, Park S, Kim YI, Park BG. The positive effects of Poria cocos extract on quality of sleep in insomnia rat models. Int J Environ Res Public Health 2022;19(11):6629. PubMed
  3. Lv Q, Di X, Bian B, Li K, Guo J. Neuroprotective effects of Poria cocos (Agaricomycetes) essential oil on Aß1-40-induced learning and memory deficit in rats. Int J Med Mushrooms 2022;24(10):73-82.

See these in context on the Poria Mushroom monograph →

Magnolia 9 references
  1. Kuribara H, Kishi E, Hattori N, et al. The anxiolytic effect of two oriental herbal drugs in Japan attributed to honokiol from magnolia bark. J Pharm Pharmacol 2000;52:1425-9. PubMed
  2. Tachikawa E, Takahashi M, Kashimoto T. Effects of extract and ingredients isolated from Magnolia obovata thunberg on catecholamine secretion from bovine adrenal chromaffin cells. Biochem Pharmacol 2000;60:433-40. PubMed
  3. Jung KY, Kim DS, Oh SR, et al. Magnone A and B, novel anti-PAF tetrahydrofuran lignans from the flower buds of Magnolia fargesii. J Nat Prod 1998;61:808-11.
  4. Garrison R, Chambliss WG. Effect of a proprietary Magnolia and Phellodendron extract on weight management: a pilot, double-blind, placebo-controlled clinical trial. Altern Ther Health Med 2006;12:50-4.
  5. Teng CM, Chen CC, Ko FN, et al. Two antiplatelet agents from Magnolia officinalis. Thromb Res 1988;50:757-65. PubMed
  6. Ghys K, De Palma A, Vandevenne A, Werbrouck J, Goossens A. Magnolia officinalis bark extract, a recently identified contact allergen in 'anti-ageing' cosmetics. Contact Dermatitis. 2015 Aug;73(2):130-2.
  7. Raison-Peyron N, Césaire A, Du-Thanh A, Dereure O. Allergic contact dermatitis caused by Magnolia officinalis bark extract in a facial anti-ageing cream. Contact Dermatitis. 2015 Jun;72(6):416-7.
  8. Nilausen TD, Johansen JD, Thyssen JP. Allergic contact dermatitis of the face caused by Magnolia officinalis bark extract. Contact Dermatitis. 2016;75(6):385-87.
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See these in context on the Magnolia monograph →

Atractylodes 6 references
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Job's Tears 3 references
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Chinese Cucumber 4 references
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Kudzu 21 references
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See these in context on the Kudzu monograph →

Chrysanthemum 25 references
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Barley 15 references
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

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