Interactions on record — worth a quick check against your medications. Check your meds →
Dietary supplement

Her Majesty's Royal Jelly Ingredients & Drug Interactions

by Cardiovascular Research

Her Majesty's Royal Jelly label
See full label image
Softgel Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Her Majesty's Royal Jelly against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Her Majesty's Royal Jelly is a dietary supplement by Cardiovascular Research with 1 active ingredient. Its ingredients are commonly taken for menopausal symptoms, skin health and wound care, immune support.Based on those ingredients, 174 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Royal Jelly. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Her Majesty's Royal Jelly by Cardiovascular Research

Ask about any prescription or over-the-counter medication and we check it for interactions with Her Majesty's Royal Jelly by Cardiovascular Research — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
Prefer a human? Send your question to our licensed pharmacists — free, answered by email within 24 hours.

HelloPharmacist Scorecard of Her Majesty's Royal Jelly by Cardiovascular Research

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 6, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • “Royal Jelly” is listed as a grouped ingredient — the label gives one combined amount (500 mg) without saying how much of each component you get.

This softgel contains one active ingredient: royal jelly concentrate (152 mg per capsule). Royal jelly is a creamy secretion made by honeybees to nourish their queen; it's rich in proteins, B vitamins, and other compounds.

The capsule itself is made from gelatin, soybean oil, glycerin, beeswax, and soy lecithin — all inactive ingredients that hold the royal jelly together.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Royal Jelly's overall clinical evidence instead.

Moderate

Some clinical evidence supports Royal Jelly for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Menopausal symptoms — rated "Possibly Effective" (Natural Medicines).

The evidence for royal jelly is mixed. It's rated possibly effective for menopausal symptoms, but possibly ineffective for hay fever, physical performance, and diabetes.

For hair loss (androgenic alopecia), there isn't enough reliable evidence to rate whether it works. If you're considering it for menopausal hot flashes or other symptoms tied to menopause, the data suggests it may help — but for the other conditions listed, the research doesn't support its use.

The evidence, ingredient by ingredient Royal Jelly

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Royal jelly is generally well tolerated in most people, but it carries a serious safety concern: it can trigger severe allergic reactions in anyone with a history of asthma or atopy (a tendency toward allergies). Common allergic symptoms include itching, hives, eczema, shortness of breath, and oral allergy syndrome.

In rare cases — especially in people prone to allergies — it can cause life-threatening anaphylaxis or severe asthma attacks. There's also one case report of bleeding in the colon after taking royal jelly.

During pregnancy, there isn't enough safety information, so it's best to avoid it. The same goes for breastfeeding — not enough data exists to know if it's safe for your baby.

Talk with your doctor or pharmacist before taking royal jelly if you're pregnant, nursing, or have a personal or family history of allergies or asthma.

Side effects, ingredient by ingredient Royal Jelly

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Royal Jelly.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 174 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, check with your doctor or pharmacist if you take warfarin or any other blood thinner — royal jelly can increase bleeding risk (Moderate severity). Also double-check any blood pressure medication you're on, as royal jelly may lower pressure further (Moderate severity).

If you have a history of asthma or allergies, that's another reason to talk to your pharmacist first.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

Royal jelly may help with menopausal symptoms, but it's a serious concern if you take blood pressure drugs or warfarin — both carry a moderate risk of harmful interactions. It's also risky if you have asthma or are prone to allergies.

Before you start, check your medications and your allergy history with your own doctor or pharmacist.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jul 25, 2013.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Her Majesty's Royal Jelly, straight from the product label.

Brand Cardiovascular Research
Net contents 60 Softgel(s)
Market status On market
Date entered into DSLD Jul 25, 2013
DSLD ID 22585
Product type Non-nutrient/non-botanical
Supplement form Softgel Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Her Majesty's Royal Jelly by Cardiovascular Research, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Softgel(s)
Maximum serving Sizes:
1 Softgel(s)
Servings per container
60
IngredientAmount% DV
Royal Jelly500 mg--
From 152 mg of Royal Jelly Concentrate152 mg--

Other ingredients: Soybean Oil, Gelatin, Glycerin, yellow Beeswax, Soy Lecithin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity

A DIETARY SUPPLEMENT

Dietary Supplement

General Statements

Her Majesty's Royal Jelly (the principle food of the Queen Bee) is a nutritional supplement containing a natural source of vitamins, amino acids, proteins and other nutrients.

11010389 EXP0114

Suggested/Recommended/Usage/Directions

DIRECTIONS Take one or two softgels daily, or as directed by a physician.

FDA Disclaimer Statement

This product has not been evaluated by the FDA. This product is not intended to diagnose, cure, treat or prevent any disease.

Seals/Symbols

ECOLOGICAL FORMULAS

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Her Majesty's Royal Jelly by Cardiovascular Research label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Her Majesty's Royal Jelly label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Her Majesty's Royal Jelly by Cardiovascular Research

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Softgel(s) Dosage formSoftgel Capsule Servings per container60 Amounts shown are per serving.

Royal Jelly

Interacts with
174 drugs
500 mg per serving

Royal jelly is a nutrient-rich substance made by worker bees to feed the queen bee. People take it for menopause symptoms, energy, skin, and immune su...

Royal Jelly monograph & interactions

Other (inactive) ingredients: Soybean Oil, Gelatin, Glycerin, Yellow Beeswax, Soy Lecithin. These complete the product’s ingredient list but are not active constituents.

Interaction report

Her Majesty's Royal Jelly by Cardiovascular Research Drug Interactions

Want to check YOUR meds against Her Majesty's Royal Jelly?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
174Drugs
174 Moderate

Ingredients driving the most interactions

Royal Jelly 174

Individual Drug Interactions

The ingredients in Her Majesty's Royal Jelly interact with 174 drugs. Click any drug to see the details.

1 of the 1 ingredient in Her Majesty's Royal Jelly interact with drugs. Each result below shows which ingredient is responsible. Royal Jelly

Each ingredient & the kinds of drugs it affects

For each ingredient in Her Majesty's Royal Jelly with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Royal Jelly2 drug types · 174 drugs

Antihypertensive Drugs

Theoretically, royal jelly might increase the risk of hypotension when taken with antihypertensive drugs.
Animal research suggests that royal jelly might lower blood pressure.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Royal jelly might increase the risk of bleeding when taken with warfarin.
In one case, an 87-year-old male who was previously stabilized on warfarin developed hematuria and was found to have an INR of 7.29 after taking a royal jelly supplement for one week.

Likelihood Possible Evidence D
Royal Jelly full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Her Majesty's Royal Jelly, from the product label.

Cardiovascular Research

See all Cardiovascular Research products
Name
CARDIOVASCULAR RESEARCH, LTD.
Street Address
1061-B SHARY CIRCLE
City
CONCORD
State
CA
ZipCode
94518
Pharmacist Counseling Corner

Her Majesty's Royal Jelly by Cardiovascular Research: Common Questions

Does Her Majesty's Royal Jelly by Cardiovascular Research interact with any medications?
Yes. Based on its ingredients, Her Majesty's Royal Jelly has a known interaction with 174 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Her Majesty's Royal Jelly contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is royal jelly safe if I have asthma or allergies?
No. People with a history of asthma or atopy (a tendency toward allergies) have a high rate of allergic reactions to royal jelly — ranging from itching and hives to, in rare cases, life-threatening anaphylaxis or severe asthma attacks. If you have either condition, talk with your doctor or pharmacist before taking this product.
Can I take this while pregnant or breastfeeding?
There isn't enough safety information to know, so it's best to avoid it during pregnancy and breastfeeding. Talk with your doctor or pharmacist for personalized advice if you're pregnant, planning to become pregnant, or nursing.
Does royal jelly actually help with hot flashes?
The evidence suggests it may — it's rated possibly effective for menopausal symptoms. However, for hay fever, physical performance, and diabetes, the evidence doesn't support its use.
What's royal jelly, exactly?
It's a creamy secretion made by honeybees to nourish their queen. It's rich in proteins, B vitamins, and other compounds that bees have relied on for centuries.
If I take warfarin, can I use this product?
Not without checking first. Royal jelly may increase your bleeding risk when combined with warfarin. One documented case involved a patient whose blood-thinning level spiked dangerously after one week on royal jelly. Talk with your doctor or pharmacist before starting.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Her Majesty's Royal Jelly is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Her Majesty's Royal Jelly label
Go deeper

The Full Monographs Behind Her Majesty's Royal Jelly’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Royal Jelly

Interacts with 174 drugs

Royal jelly is a nutrient-rich substance made by worker bees to feed the queen bee. People take it for menopause symptoms, energy, skin, and immune support, but solid human evidence is limit...

Read the full Royal Jelly monograph →
Sources

Sources & How We Checked

Her Majesty's Royal Jelly's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 14 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Royal Jelly 14 references
  1. Takahashi M, Matsuo I, Ohkido M. Contact dermatitis due to honeybee royal jelly. Contact Dermatitis 1983;9:452-5.
  2. Bullock RJ, et al. Fatal royal jelly-induced asthma. Med J Aust 1994;160:44. DOI
  3. Thien FC, Leung R, Baldo BA, et al. Asthma and anaphylaxis induced by royal jelly. Clin Exp Allergy 1996;26:216-22. PubMed
  4. Yonei Y, Shibagaki K, Tsukada N, et al. Case report: haemorrhagic colitis associated with royal jelly intake. J Gastroenterol Hepatol 1997;12:495-9.
  5. Harwood M, Harding S, Beasley R, Frankish PD. Asthma following royal jelly. N Z Med J 1996;109:325.
  6. Laporte JR, Ibaanez L, Vendrell L, Ballarin E. Bronchospasm induced by royal jelly. Allergy 1996;51:440. DOI
  7. Leung R, Thien FC, Baldo B, et al. Royal jelly-induced asthma and anaphylaxis: clinical characteristics and immunologic correlations. J Allergy Clin Immunol 1995;96:1004-7. PubMed
  8. Peacock S, Murray V, Turton C. Respiratory distress and royal jelly. BMJ 1995;311:1472. DOI
  9. Winther K, Hedman C. Assessment of the Effects of the Herbal Remedy Femal on the Symptoms of Premenstrual Syndrome: A Randomized, Double-Blind, Placebo-Controlled Study. Curr Ther Res Clin Exp 2002;63:344-53. DOI
  10. Lee NJ, Fermo JD. Warfarin and royal jelly interaction. Pharmacotherapy 2006;26:583-6. PubMed
  11. Tokunaga, K. H., Yoshida, C., Suzuki, K. M., Maruyama, H., Futamura, Y., Araki, Y., and Mishima, S. Antihypertensive effect of peptides from royal jelly in spontaneously hypertensive rats. Biol.Pharm.Bull. 2004;27(2):189-192. PubMed
  12. Sultana, A., Nabi, A. H., Nasir, U. M., Maruyama, H., Suzuki, K. M., Mishima, S., and Suzuki, F. A dipeptide YY derived from royal jelly proteins inhibits renin activity. Int.J.Mol.Med. 2008;21(6):677-681. DOI
  13. Gómez Torrijos E, Méndez Diaz Y, Borja Segade JM, et al. Occupational allergic respiratory disease due to royal jelly. Ann Allergy Asthma Immunol. 2016;117(1):102-3. PubMed
  14. Li JD, Cui L, Xu YY, Guan K. A case of anaphylaxis caused by major royal jelly protein 3 of royal jelly and its cross-reactivity with honeycomb. J Asthma Allergy 2021;14:1555-7. PubMed

See these in context on the Royal Jelly monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring
Supplement interaction checker › Check any supplement or product against your medications Drug–drug interactions › Check two or more of your medications against each other Browse medications A–Z › Every drug we've checked against herbs & supplements NDC & pricing lookup › Find a drug’s NDCs, packaging and costs Ask a pharmacist › Free, personal answer from our licensed team