Interactions on record — worth a quick check against your medications. Based on 1 of 2 ingredients. Check your meds →
Dietary supplement

High Potency Elderberry Fruit Extract Supplement 600 mg Ingredients & Drug Interactions

by Vitals

Capsule Category: Botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

High Potency Elderberry Fruit Extract Supplement 600 mg is a dietary supplement by Vitals with 2 active ingredients. Its ingredients are commonly taken for colds, flu (influenza), other respiratory infections.Based on those ingredients, 121 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Elderberry Fruit Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of High Potency Elderberry Fruit Extract Supplement 600 mg by Vitals

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This supplement contains 2 active ingredients, both of which are Elderberry Fruit Extract — a concentrated form of the fruit from the elderberry plant. The extract is standardized to 600 mg per capsule.

The inactive ingredients (cellulose, rice flour, and magnesium stearate) are fillers and capsule materials that help deliver the active ingredient.

Does it work?

Insufficient evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Insufficient

There isn't enough reliable clinical evidence to rate this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: immune support and respiratory health.
  • We looked for evidence on: Upper respiratory tract infection (URTI), Lower respiratory tract infections, Respiratory tract infections, Rhinosinusitis, colds, influenza — and 1 related terms.
  • The closest evidence on file: Elderberry is rated "Insufficient Reliable Evidence To Rate" for Lower respiratory tract infections (Natural Medicines).
  • Also on file: Elderberry is rated "Insufficient Reliable Evidence To Rate" for Rhinosinusitis.

The evidence for what elderberry actually does isn't established in the data we hold. For allergic rhinitis (hay fever), cardiovascular disease, chronic fatigue syndrome, COPD, cognitive function, and respiratory tract infections, the safety and effectiveness data we have rates as insufficient to know whether it works.

That doesn't mean it doesn't — it means the research isn't solid enough yet to say.

The evidence, ingredient by ingredient Elderberry

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Properly prepared elderberry extracts from ripe fruit are generally well tolerated. However, raw or unripe berries, leaves, bark, and seeds can be toxic and cause nausea, vomiting, severe diarrhea, weakness, dizziness, numbness, and even stupor due to compounds called cyanogenic glycosides — cooking removes this toxin.

During pregnancy, there isn't enough reliable safety information, so it's best to avoid elderberry supplements. The same goes for breastfeeding.

If you're pregnant or nursing and interested in elderberry, talk with your doctor or pharmacist for personalized advice.

Side effects, ingredient by ingredient Elderberry

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Elderberry.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: immunosuppressants / transplant drugs.
  • For scale: 121 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take this, double-check if you're on immunosuppressants (drugs that quiet your immune system after transplant or for autoimmune conditions) or pazopanib (a cancer medication). Both have Moderate interactions with elderberry.

Run your exact medications through the checker below.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with insufficient evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Elderberry might be worth considering if you want to explore natural immune support, but it's not the right fit if you take immunosuppressants, pazopanib, or other transplant or cancer drugs. Pregnant and nursing people should avoid it.

Always check your medications with the tool on this page before you start.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Aug 22, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about High Potency Elderberry Fruit Extract Supplement 600 mg, straight from the product label.

Brand Vitals
Barcode (UPC) 722777723974
Net contents 60 Capsule(s)
Market status On market
Date entered into DSLD Aug 22, 2024
DSLD ID 316160
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for High Potency Elderberry Fruit Extract Supplement 600 mg by Vitals, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Veggie Capsule(s)
Maximum serving Sizes:
1 Veggie Capsule(s)
Servings per container
60
UPC/BARCODE
722777723974
IngredientAmount% DV
Elderberry Fruit Extract275 mg--
Elderberry Fruit Extract325 mg--

Other ingredients: Cellulose, Rice Flour, Magnesium Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested Use: As a dietary supplement, take two (2) veggie capsules twice a day. For best results take 20-30 min before meal with 8 oz. glass of water or as directed by your healthcare professional.

Precautions

Caution: Do not exceed recommended dose.

Pregnant or nursing mothers, children under the age of 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement.

Pregnant or nursing mothers, children under the age of 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement. Keep out of reach of children.

Do not use if safety seal is damaged or missing.

Storage

Store in a cool, dry place.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

General Statements

SKU 26162-825

Formula

High Potency Elderberry Fruit Extract Supplement Max Strength 600 mg

FDA Statement of Identity

Dietary Supplement

Formulation

FDA Registered Facility

GMO Free Gluten Free Lactose Free BPA Free

Manufactured & Tested in the USA FDA Registered Facility

Brand IP Statement(s)

Copyright Vitals All Rights Reserved

Seals/Symbols

Made in the USA

See for yourself

High Potency Elderberry Fruit Extract Supplement 600 mg by Vitals label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in High Potency Elderberry Fruit Extract Supplement 600 mg by Vitals

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Veggie Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Elderberry Fruit Extract

Interacts with
121 drugs
275 mg per serving

Elderberry is a popular herbal supplement, mainly taken to help with colds and flu. Some small studies suggest it may modestly shorten cold or flu sym...

Elderberry Fruit Extract monograph & interactions

Elderberry Fruit Extract

Interacts with
121 drugs
325 mg per serving Form: Flavonoid

Elderberry is a popular herbal supplement, mainly taken to help with colds and flu. Some small studies suggest it may modestly shorten cold or flu sym...

Elderberry Fruit Extract monograph & interactions

Other (inactive) ingredients: Cellulose, Rice Flour, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

High Potency Elderberry Fruit Extract Supplement 600 mg by Vitals Drug Interactions

Want to check YOUR meds against High Potency Elderberry Fruit Extract Supplement 600 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
121Drugs
121 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in High Potency Elderberry Fruit Extract Supplement 600 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Elderberry Fruit Extract2 drug types · 121 drugs

Immunosuppressants

Theoretically, elderberry might interfere with immunosuppressant therapy due to its immunostimulant activity.
Elderberry has immunostimulant activity, increasing the production of cytokines, including interleukin and tumor necrosis factor.

Likelihood Possible Evidence B
Pazopanib (Votrient)

Theoretically, elderberry might interact with pazopanib, potentially increasing the risk of adverse effects.
In one case, a 65-year-old patient taking pazopanib for 4 weeks for soft-tissue sarcoma developed severe nausea, loose stools, and elevated alanine transaminase and aspartate transaminase levels and was diagnosed with grade 3 liver injury. The patient reported taking elderberry supplements for 2 years, dose unspecified, and was also taking a multivitamin and a calcium supplement. The patient's symptoms and liver enzyme levels improved upon discontinuation of pazopanib and all supplements. Pazopanib treatment was re-initiated, at a lower dose, with no further evidence of liver injury. It was unclear in this case report if the elderberry supplements were derived from the berry, the flower, or the combination.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for High Potency Elderberry Fruit Extract Supplement 600 mg, from the product label.

Vitals

See all Vitals products
Name
Vitals
Street Address
5647 W. Wells Park Rd
City
West Jordan
State
UT
ZipCode
84081
Phone Number
+1 (628) 201-0240
Web Address
vitals-health.com
Pharmacist Counseling Corner

High Potency Elderberry Fruit Extract Supplement 600 mg by Vitals: Common Questions

Does High Potency Elderberry Fruit Extract Supplement 600 mg by Vitals interact with any medications?
Yes. Based on its ingredients, High Potency Elderberry Fruit Extract Supplement 600 mg has a known interaction with 121 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
High Potency Elderberry Fruit Extract Supplement 600 mg contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is this supplement safe if I'm pregnant?
The safety data for elderberry supplements in pregnancy isn't reliable enough to say it's safe. It's best to avoid it while pregnant. Talk with your doctor or pharmacist about whether elderberry makes sense for you.
What happens if I take elderberry when I'm breastfeeding?
There isn't enough safety information about elderberry during breastfeeding, so it's best to avoid supplements during this time. Chat with your doctor or pharmacist if you'd like to use elderberry while nursing.
I heard raw elderberries can make you sick — is this product safe?
Yes. This is an extract made from ripe fruit that's been properly prepared. Raw or unripe berries, seeds, leaves, and bark contain a toxic compound that can cause nausea, vomiting, and diarrhea — but cooking (which this product undergoes) eliminates that toxin. Properly prepared elderberry extracts are well tolerated.
Does elderberry actually help with colds or the flu?
The evidence we have for elderberry and respiratory tract infections doesn't tell us whether it works or not — the research isn't solid enough yet to say. You'd want to talk with your pharmacist about what the current science shows.
What side effects might I notice?
Elderberry extracts prepared from ripe fruit are generally well tolerated, and most people don't report side effects. If you do have symptoms like nausea or vomiting, they're usually linked to raw or unripe berries — not the cooked extract in this product. One case report described a woman who took elderberry for years and later developed liver inflammation, though she had an underlying autoimmune disease.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if High Potency Elderberry Fruit Extract Supplement 600 mg is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

High Potency Elderberry Fruit Extract Supplement 600 mg label
Go deeper

The Full Monographs Behind High Potency Elderberry Fruit Extract Supplement 600 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

High Potency Elderberry Fruit Extract Supplement 600 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 6 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Elderberry 6 references
  1. Barak V, Halperin T, Kalickman I. The effect of Sambucol, a black elderberry-based, natural product, on the production of human cytokines: I. Inflammatory cytokines. Eur Cytokine Netw 2001;12:290-6..
  2. Elderberry (Sambucus species). The Poison Plant Patch, Novia Scotia Museum, 2007. Available at: http://museum.gov.ns.ca/poison/?section=species&id=117 (Accessed 16 October 2009).
  3. European elder. Canadian Poisonous Plants Information System. Available at: http://www.cbif.gc.ca/pls/pp/ppack.jump?p_null=all&p_psn=121&p_type=all&p_sci=comm&p_x=px (Accessed 16 October 2009).
  4. Raus K, Pleschka S, Klein P, Schoop R, Fisher P. Effect of an echinacea-based hot drink versus oseltamivir in Influenza treatment: a randomized, double-blind, double-dummy, multicenter, noninferiority clinical trial. . Curr Ther Res Clin Exp. 2015;20;77:6 PubMed
  5. Ramachandran A, Antala D, Pudasainee P, Panginikkod S, Gupta H. A Plausible Association Between the Use of Elderberry and Autoimmune Hepatitis. Cureus 2022;14(4):e24250. PubMed
  6. Agarwal N, Mangla A. Elderberry interaction with pazopanib in a patient with soft-tissue sarcoma: A case report and literature review. Mol Clin Oncol 2024;20(5):36. PubMed

See these in context on the Elderberry monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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