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Dietary supplement

Hoodia Ingredients & Drug Interactions

by Desert Burn

Hoodia label
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Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Hoodia against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Hoodia is a dietary supplement by Desert Burn with 1 active ingredient. Its ingredients are commonly taken for appetite suppression, weight loss, reducing food cravings.Based on those ingredients, 262 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are South African Hoodia gordonii. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Hoodia by Desert Burn

Ask about any prescription or over-the-counter medication and we check it for interactions with Hoodia by Desert Burn — and tell you which ingredient is responsible.

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Computed from our clinical databases

HelloPharmacist Scorecard of Hoodia by Desert Burn

Four independent checks of what is known — a summary of the available information, not a grade of the product itself.

Evidence for Intended Use
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

The stated purpose hasn't been mapped to our evidence data yet.

Why this rating?
  • We haven't mapped this product's purpose to our evidence data yet — it'll be graded on the next content refresh.
Ingredient Transparency
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.
Known Interaction Concern
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Hoodia.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 262 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.
Safety Information
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

HelloPharmacist summaryFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Mar 23, 2012.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Hoodia, straight from the product label.

Brand Desert Burn
Net contents 180 Liquid Veggie Cap(s)
Market status Off market
Date entered into DSLD Mar 23, 2012
DSLD ID 7018
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Hoodia by Desert Burn, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
6 Vegetarian Capsule(s)
Maximum serving Sizes:
6 Vegetarian Capsule(s)
Servings per container
30
IngredientAmount% DV
South African Hoodia gordonii1500 mg--

Other ingredients: non-GMO Soy Lecithin, Modified Vegetable Cellulose

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

SUGGESTED USE: Take six (6) liquid filled Desert Burn(R) veggie caps in the morning with a glass of water as a dietary supplement. For best results repeat process one hour before lunch time and if needed an hour before supper until you finish the bottle or as directed by your healthcare professional. Combine Desert Burn(R) with a sensible diet low in carbs and consider light exercise such as walking 20 minutes or 1 mile per day.

Seals/Symbols

(DESERT BURN(R) STAMP OF AUTHENTICITY REAL-HOODIAGORDONI)

General Statements

LAB CERTIFIED AUTHENTIC SOUTH AFRICAN HOODIA GORDONII

THE GOLD STANDARD FOR HOODIA GORDONII WORLDWIDE

PROFESSIONAL GRADE NEW LIQUID TECHNOLOGY

Our Hoodia gordonii is imported from Africa and is quality tested by independent testing labs for Hoodia authentication and Hoodia steroidal glycoside content.

JOB 22:25 Yea, the Almighty shall by they defense, and thou shalt have plenty of silver.

To report an adverse event: 1-702-430-1970.

Formulation

100% VEGETARIAN

Contains no milk or milk by-products, gluten, sugar, yeast, artificial colors, dyes, flavors or preservatives.

FDA Statement of Identity

DIETARY SUPPLEMENT

Brand IP Statement(s)

(c)2004-2012 Copyright DESERT BURN(R)

Precautions

CAUTION: Do not exceed recommended dose.

This product is not to be taken by pregnant or nursing mothers, children under 18 or individuals with any known medical condition.

Do not purchase if seal is broken or missing.

Keep out of reach of children.

Storage

Store Desert Burn(R) in a cool, dry place.

FDA Disclaimer Statement

The statements on this label have not been evaluated by the Food and Drug Administration (FDA). This product is not intended to diagnose, treat, cure, or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Hoodia by Desert Burn label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Hoodia label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Hoodia by Desert Burn

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size6 Vegetarian Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

South African Hoodia gordonii

Interacts with
262 drugs
1500 mg per serving

Hoodia is a succulent plant from southern Africa that is marketed as an appetite suppressant for weight loss, but solid human evidence that it actuall...

South African Hoodia gordonii monograph & interactions

Other (inactive) ingredients: Non-GMO Soy Lecithin, Modified Vegetable Cellulose. These complete the product’s ingredient list but are not active constituents.

Interaction report

Hoodia by Desert Burn Drug Interactions

Hoodia contains a single active ingredient, and it has known interactions with 262 medications. Here’s the picture, then you can look up your own drug.

Want to check YOUR meds against Hoodia?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
262Drugs
262 Moderate

Ingredients driving the most interactions

South African Hoodia gordonii 262

Individual Drug Interactions

The ingredients in Hoodia interact with 262 drugs. Click any drug to see the details.

1 of the 1 ingredient in Hoodia interact with drugs. Each result below shows which ingredient is responsible. South African Hoodia gordonii

Each ingredient & the kinds of drugs it affects

For each ingredient in Hoodia with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

South African Hoodia gordonii4 drug types · 262 drugs

Antidiabetes Drugs

Animal research shows that a steroid glycoside of hoodia, gordonoside F, increases glucose-stimulated insulin secretion by activating GPR119. This effect enhances glucose disposal. Theoretically, concomitant use of hoodia with antidiabetes medications may enhance blood glucose-lowering effects and increase the risk of hypoglycemia. Some antidiabetes medications include glimepiride (Amaryl), glyburide (DiaBeta, Glynase PresTab, Micronase), insulin, pioglitazone (Actos), rosiglitazone (Avandia), chlorpropamide (Diabinese), glipizide (Glucotrol), tolbutamide (Orinase), and others.

Likelihood Possible Evidence D
Antihypertensive Drugs

Clinical research shows that hoodia can increase blood pressure. Theoretically, concomitant use of hoodia with antihypertensive drugs might decrease the effectiveness of the antihypertensive drugs and increase the risk of hypertension. Some antihypertensive drugs include captopril (Capoten), enalapril (Vasotec), losartan (Cozaar), valsartan (Diovan), diltiazem (Cardizem), Amlodipine (Norvasc), hydrochlorothiazide (HydroDiuril), furosemide (Lasix), and many others.

Likelihood Possible Evidence D
Beta-Blockers

Evidence from in vitro research shows that hoodia may stimulate beta-adrenergic receptors. Also, clinical research shows that hoodia can increase blood pressure and heart rate. Theoretically, using hoodia with beta-blockers might decrease the effects of these medications. Some beta-blocker drugs include atenolol (Tenormin), metoprolol (Lopressor, Toprol XL), nadolol (Corgard), and propranolol (Inderal).

Likelihood Possible Evidence D
Insulin

Animal research shows that a steroid glycoside of hoodia, gordonoside F, increases glucose-stimulated insulin secretion by activating GPR119. Theoretically, concomitant use of hoodia with insulin may enhance the blood glucose-lowering effects of insulin. Blood glucose levels should be monitored.

Likelihood Possible Evidence D
South African Hoodia gordonii full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Hoodia, from the product label.

Desert Burn

See all Desert Burn products
Phone Number
1-702-430-1970
Pharmacist Counseling Corner

Hoodia by Desert Burn: Common Questions

Does Hoodia by Desert Burn interact with any medications?
Yes. Based on its ingredients, Hoodia has a known interaction with 262 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Hoodia contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Hoodia label
Go deeper

The Full Monographs Behind Hoodia’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Hoodia

Interacts with 262 drugs

Hoodia is a succulent plant from southern Africa that is marketed as an appetite suppressant for weight loss, but solid human evidence that it actually works is lacking. The few quality stud...

Read the full Hoodia monograph →
Sources

Sources & How We Checked

Hoodia's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 3 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Hoodia 3 references
  1. Blom WAM, Abrahamse SL, Bradford R, et al. Effects of 15-d repeated consumption of Hoodia gordonii purified extract on safety, ad libitum energy intake, and body weight in healthy, overweight women: a randomized controlled trial. Am J Clin Nutr 2011;94(5) PubMed
  2. Roza O, Lovász N, Zupkó I, Hohmann J, Csupor D. Sympathomimetic activity of a Hoodia gordonii product: a possible mechanism of cardiovascular side effects. Biomed Res Int. 2013;2013:171059.
  3. Zhang S, Ma Y, Li J, et al. Molecular matchmaking between the popular weight-loss herb Hoodia gordonii and GPR119, a potential drug target for metabolic disorder. Proc Natl Acad Sci U S A. 2014;111(40):14571-6.

See these in context on the Hoodia monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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