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Dietary supplement

Humic Fulvic Acid Complex Ingredients & Drug Interactions

by Dr. Mercola

Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Humic Fulvic Acid Complex is a dietary supplement by Dr. Mercola with 2 active ingredients. Its ingredients are commonly taken for general wellness and energy, gut health, antioxidant support.Based on those ingredients, 257 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Fulvic Acid. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Humic Fulvic Acid Complex by Dr. Mercola

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This product has 2 active ingredients: fulvic acid and humic acids. Fulvic acid is a compound derived from the breakdown of organic matter; humic acids are structurally similar compounds.

Both are marketed for various wellness purposes, though evidence for their effectiveness is limited. The capsules also contain rice bran and hydroxypropyl methylcellulose as inactive ingredients.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

The label doesn't state a purpose we can grade — see each ingredient's own graded uses on its monograph instead.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence for fulvic acid in this product is not established for the uses it's commonly promoted for. Our data show insufficient reliable evidence to rate its effectiveness for respiratory tract infections, lead toxicity, atopic dermatitis (eczema), fatigue, and allergic rhinitis (hay fever).

We hold no effectiveness information for humic acids.

The evidence, ingredient by ingredient Fulvic Acid Humic Acid

How safe is it?

Some data gaps
Safety Information · database check
Some gaps

Safety data exists for these ingredients, but with some important gaps.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 1 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Fulvic acid appears to be generally well tolerated in the short term, though high-quality human safety data are limited. In clinical trials, some people reported diarrhea, headache, and sore throat.

A rare serious effect called Kashin-Beck bone disease has been reported with oral use, though this is uncommon. There is not enough safety information to recommend this product during pregnancy or while breastfeeding — the facts advise against both.

Humic acids also lack sufficient safety data in pregnancy and lactation, and product purity varies, so use with caution.

Side effects, ingredient by ingredient Fulvic Acid Humic Acid

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 2 matched ingredients can interact with medications — Fulvic Acid.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs.
  • For scale: 257 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your pharmacist before using this product if you take blood thinners or antiplatelet drugs (such as warfarin or aspirin), thyroid hormone medication, or immunosuppressant drugs. Fulvic acid may reduce how well these work.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and some safety-information gaps remain.

This product may appeal to people looking for general wellness support, but the evidence for what it claims to do isn't established. If you take blood thinners, thyroid medication, or immunosuppressant drugs, you'll want to talk with your pharmacist before trying it.

Pregnant or breastfeeding? Skip it for now — the safety data just aren't there yet.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jan 23, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Humic Fulvic Acid Complex, straight from the product label.

Brand Dr. Mercola
Barcode (UPC) 810094213657
Net contents 30 Capsule(s)
Market status On market
Date entered into DSLD Jan 23, 2025
DSLD ID 327172
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Humic Fulvic Acid Complex by Dr. Mercola, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
30
UPC/BARCODE
810094213657
IngredientAmount% DV
Fulvic Acid33 mg--
Humic Acids90 mg--

Other ingredients: Rice Bran, Hydroxypropyl Methylcellulose

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested Use: Adults, as a dietary supplement, take one (1) capsule daily.

Precautions

Keep out of reach of children.

Do not use if safety seal is broken.

If you are nursing, pregnant, taking medication or have a medical condition, consult your physician before taking this product.

Formula

90 mg Humic Acid & 33 mg Fulvic Acid Per Serving

FDA Statement of Identity

Dietary Supplement

General Statements

Providing quality products since 2001.

See for yourself

Humic Fulvic Acid Complex by Dr. Mercola label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Humic Fulvic Acid Complex by Dr. Mercola

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Fulvic Acid

Interacts with
257 drugs
33 mg per serving

Fulvic acid is a natural compound formed when plants and microbes break down in soil, and it is sold as a supplement for energy, gut, and overall well...

Fulvic Acid monograph & interactions

Humic Acids

No known
interactions
90 mg per serving

Humic acid is a natural substance formed when plant and animal matter break down in soil, peat, and coal-like deposits, and it is sold as a supplement...

Humic Acids monograph & interactions

Other (inactive) ingredients: Rice Bran, Hydroxypropyl Methylcellulose. These complete the product’s ingredient list but are not active constituents.

Interaction report

Humic Fulvic Acid Complex by Dr. Mercola Drug Interactions

Want to check YOUR meds against Humic Fulvic Acid Complex?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
257Drugs
257 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Humic Fulvic Acid Complex with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Fulvic Acid3 drug types · 257 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, taking fulvic acid may decrease the effectiveness of anticoagulant and antiplatelet drugs.
In vitro evidence shows that fulvic acid, formed from the oxidation and polymerization of protocatechuic acid, can shorten prothrombin time in human plasma, increasing the risk of clot formation.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, taking fulvic acid might decrease the effects of immunosuppressive therapy.
Animal research shows that fulvic acid stimulates immune function.

Likelihood Possible Evidence D
Thyroid Hormone

Theoretically, taking fulvic acid with thyroid hormone therapy might interfere with the ability to normalize thyroid function.
Animal research shows that fulvic acid increases the plasma level of thyroid-stimulating hormone (TSH) and decreases the thyroxine (T4):triiodothyronine (T3) ratio.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Humic Fulvic Acid Complex, from the product label.

Dr. Mercola

See all Dr. Mercola products
Name
NHP
Street Address
125 SW 3rd Place
City
Cape Coral
State
FL
ZipCode
33991
Phone Number
(877) 985-2696
Pharmacist Counseling Corner

Humic Fulvic Acid Complex by Dr. Mercola: Common Questions

Does Humic Fulvic Acid Complex by Dr. Mercola interact with any medications?
Yes. Based on its ingredients, Humic Fulvic Acid Complex has a known interaction with 257 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Humic Fulvic Acid Complex contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What are fulvic acid and humic acids?
Fulvic acid is a compound formed from the breakdown of organic matter in soil. Humic acids are related compounds with a similar source. Both are found naturally in soil and water, and they're marketed as dietary supplements for various health purposes.
Does this product actually work for anything?
Our data show insufficient reliable evidence to rate fulvic acid for common uses like respiratory infections, fatigue, eczema, hay fever, or lead toxicity. We have no effectiveness information for humic acids in this product.
What side effects should I watch for?
In clinical trials, some people experienced diarrhea, headache, and sore throat. Serious effects are rare but include a bone condition called Kashin-Beck disease. Overall, short-term use appears well tolerated, though long-term human safety data are limited.
Is it safe during pregnancy or breastfeeding?
No — there's not enough safety information for either. The safety data advise against use in both pregnancy and while breastfeeding. Talk with your doctor or pharmacist for personalized advice if you're considering it.
Can I take this with my blood thinner?
Not without checking with your pharmacist first. Fulvic acid may reduce how well blood thinners work, raising your clot risk. Your pharmacist can review your exact medication and help you decide.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Humic Fulvic Acid Complex is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Humic Fulvic Acid Complex label
Sources

Sources & How We Checked

Humic Fulvic Acid Complex's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 6 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Fulvic Acid 3 references
  1. Lu, FJ. Arsenic as a promoter in the effect of humic substances on plasma prothrombin time in vitro. Thromb Res 6-15-1990;58(6):537-541. PubMed
  2. Vucskits, AV, Hullar, I, Bersenyi, A, Andrasofszky, E, Kulcsar, M, Szabo, J. Effect of fulvic and humic acids on performance, immune response and thyroid function in rats. J Anim Physiol Anim Nutr (Berl) 2010;94(6):721-728. PubMed
  3. Gandy JJ, Meeding JP, Snyman JR, et al. Phase 1 clinical study of the acute and subacute safety and proof-of-concept efficacy of carbohydrate-derived fulvic acid. Clin Pharmacol. 2012;4:7-11. PubMed

See these in context on the Fulvic Acid monograph →

Humic Acid 3 references
  1. Dietary Supplements: What You Need to Know — NIH Office of Dietary Supplements Source
  2. Using Dietary Supplements Wisely — NIH NCCIH Source
  3. Dietary Supplements — MedlinePlus Source

See these in context on the Humic Acid monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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